Treatment of hypophonia with collagen vocal cord augmentation in patients with parkinsonism.
Identifieur interne : 000C04 ( Ncbi/Checkpoint ); précédent : 000C03; suivant : 000C05Treatment of hypophonia with collagen vocal cord augmentation in patients with parkinsonism.
Auteurs : Amy N. Hill [États-Unis] ; Joseph Jankovic [États-Unis] ; Kevin D A T. Vuong ; Don DonovanSource :
- Movement disorders : official journal of the Movement Disorder Society [ 0885-3185 ] ; 2003.
English descriptors
- KwdEn :
- Aged, Aged, 80 and over, Collagen (therapeutic use), Drug Administration Schedule, Female, Humans, Male, Parkinsonian Disorders (complications), Parkinsonian Disorders (physiopathology), Patient Satisfaction, Questionnaires, Time Factors, Treatment Outcome, Vocal Cords (drug effects), Voice Disorders (drug therapy), Voice Disorders (etiology), Voice Disorders (physiopathology), Voice Quality.
- MESH :
- chemical , therapeutic use : Collagen.
- complications : Parkinsonian Disorders.
- drug effects : Vocal Cords.
- drug therapy : Voice Disorders.
- etiology : Voice Disorders.
- physiopathology : Parkinsonian Disorders, Voice Disorders.
- Aged, Aged, 80 and over, Drug Administration Schedule, Female, Humans, Male, Patient Satisfaction, Questionnaires, Time Factors, Treatment Outcome, Voice Quality.
Abstract
We conducted structured interviews of patients with Parkinson's disease (PD) and other parkinsonian disorders and their caregivers after augmentation of vocal folds with collagen injections. A total of 12 patients (mean age, 73.7 +/- 8.6 years) completed the questionnaire after an average of 3.0 +/- 1.7 collagen injections, with an average of 13.8 +/- 7.4 weeks between each injection. In addition to improvement in all six voice quality questions, there was significant improvement (P < 0.05) in the Glascow Benefit Inventory (GBI) score. The injection procedure was tolerated well by patients with an average duration of benefit lasting 7.8 +/- 8.5 weeks. Augmentation of vocal folds with collagen provides temporary improvement in voice in patients with parkinsonian hypophonia.
DOI: 10.1002/mds.10554
PubMed: 14534926
Affiliations:
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pubmed:14534926Le document en format XML
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<author><name sortKey="Hill, Amy N" sort="Hill, Amy N" uniqKey="Hill A" first="Amy N" last="Hill">Amy N. Hill</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Neurology, Baylor College of Medicine, Houston, Texas 77030, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Neurology, Baylor College of Medicine, Houston, Texas 77030</wicri:regionArea>
<wicri:noRegion>Texas 77030</wicri:noRegion>
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<author><name sortKey="Jankovic, Joseph" sort="Jankovic, Joseph" uniqKey="Jankovic J" first="Joseph" last="Jankovic">Joseph Jankovic</name>
<affiliation><country>États-Unis</country>
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<author><name sortKey="Jankovic, Joseph" sort="Jankovic, Joseph" uniqKey="Jankovic J" first="Joseph" last="Jankovic">Joseph Jankovic</name>
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<series><title level="j">Movement disorders : official journal of the Movement Disorder Society</title>
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<term>Drug Administration Schedule</term>
<term>Female</term>
<term>Humans</term>
<term>Male</term>
<term>Parkinsonian Disorders (complications)</term>
<term>Parkinsonian Disorders (physiopathology)</term>
<term>Patient Satisfaction</term>
<term>Questionnaires</term>
<term>Time Factors</term>
<term>Treatment Outcome</term>
<term>Vocal Cords (drug effects)</term>
<term>Voice Disorders (drug therapy)</term>
<term>Voice Disorders (etiology)</term>
<term>Voice Disorders (physiopathology)</term>
<term>Voice Quality</term>
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<keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Collagen</term>
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</keywords>
<keywords scheme="MESH" qualifier="drug effects" xml:lang="en"><term>Vocal Cords</term>
</keywords>
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<term>Aged, 80 and over</term>
<term>Drug Administration Schedule</term>
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<term>Male</term>
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<front><div type="abstract" xml:lang="en">We conducted structured interviews of patients with Parkinson's disease (PD) and other parkinsonian disorders and their caregivers after augmentation of vocal folds with collagen injections. A total of 12 patients (mean age, 73.7 +/- 8.6 years) completed the questionnaire after an average of 3.0 +/- 1.7 collagen injections, with an average of 13.8 +/- 7.4 weeks between each injection. In addition to improvement in all six voice quality questions, there was significant improvement (P < 0.05) in the Glascow Benefit Inventory (GBI) score. The injection procedure was tolerated well by patients with an average duration of benefit lasting 7.8 +/- 8.5 weeks. Augmentation of vocal folds with collagen provides temporary improvement in voice in patients with parkinsonian hypophonia.</div>
</front>
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<region><li>Texas</li>
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<settlement><li>Houston</li>
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<orgName><li>Baylor College of Medicine</li>
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<tree><noCountry><name sortKey="Donovan, Don" sort="Donovan, Don" uniqKey="Donovan D" first="Don" last="Donovan">Don Donovan</name>
<name sortKey="Vuong, Kevin D A T" sort="Vuong, Kevin D A T" uniqKey="Vuong K" first="Kevin D A T" last="Vuong">Kevin D A T. Vuong</name>
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<country name="États-Unis"><noRegion><name sortKey="Hill, Amy N" sort="Hill, Amy N" uniqKey="Hill A" first="Amy N" last="Hill">Amy N. Hill</name>
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<name sortKey="Jankovic, Joseph" sort="Jankovic, Joseph" uniqKey="Jankovic J" first="Joseph" last="Jankovic">Joseph Jankovic</name>
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