Movement Disorders (revue)

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Treatment of hypophonia with collagen vocal cord augmentation in patients with parkinsonism.

Identifieur interne : 000C04 ( Ncbi/Curation ); précédent : 000C03; suivant : 000C05

Treatment of hypophonia with collagen vocal cord augmentation in patients with parkinsonism.

Auteurs : Amy N. Hill [États-Unis] ; Joseph Jankovic [États-Unis] ; Kevin D A T. Vuong ; Don Donovan

Source :

RBID : pubmed:14534926

English descriptors

Abstract

We conducted structured interviews of patients with Parkinson's disease (PD) and other parkinsonian disorders and their caregivers after augmentation of vocal folds with collagen injections. A total of 12 patients (mean age, 73.7 +/- 8.6 years) completed the questionnaire after an average of 3.0 +/- 1.7 collagen injections, with an average of 13.8 +/- 7.4 weeks between each injection. In addition to improvement in all six voice quality questions, there was significant improvement (P < 0.05) in the Glascow Benefit Inventory (GBI) score. The injection procedure was tolerated well by patients with an average duration of benefit lasting 7.8 +/- 8.5 weeks. Augmentation of vocal folds with collagen provides temporary improvement in voice in patients with parkinsonian hypophonia.

DOI: 10.1002/mds.10554
PubMed: 14534926

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pubmed:14534926

Le document en format XML

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<nlm:affiliation>Department of Neurology, Baylor College of Medicine, Houston, Texas 77030, USA.</nlm:affiliation>
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<name sortKey="Jankovic, Joseph" sort="Jankovic, Joseph" uniqKey="Jankovic J" first="Joseph" last="Jankovic">Joseph Jankovic</name>
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<term>Aged</term>
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<term>Collagen (therapeutic use)</term>
<term>Drug Administration Schedule</term>
<term>Female</term>
<term>Humans</term>
<term>Male</term>
<term>Parkinsonian Disorders (complications)</term>
<term>Parkinsonian Disorders (physiopathology)</term>
<term>Patient Satisfaction</term>
<term>Questionnaires</term>
<term>Time Factors</term>
<term>Treatment Outcome</term>
<term>Vocal Cords (drug effects)</term>
<term>Voice Disorders (drug therapy)</term>
<term>Voice Disorders (etiology)</term>
<term>Voice Disorders (physiopathology)</term>
<term>Voice Quality</term>
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<term>Collagen</term>
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<keywords scheme="MESH" qualifier="complications" xml:lang="en">
<term>Parkinsonian Disorders</term>
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<keywords scheme="MESH" qualifier="drug effects" xml:lang="en">
<term>Vocal Cords</term>
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<keywords scheme="MESH" qualifier="drug therapy" xml:lang="en">
<term>Voice Disorders</term>
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<keywords scheme="MESH" qualifier="etiology" xml:lang="en">
<term>Voice Disorders</term>
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<keywords scheme="MESH" qualifier="physiopathology" xml:lang="en">
<term>Parkinsonian Disorders</term>
<term>Voice Disorders</term>
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