Further case of paroxysmal exercise-induced dystonia and some insights into pathogenesis.
Identifieur interne : 000963 ( Ncbi/Checkpoint ); précédent : 000962; suivant : 000964Further case of paroxysmal exercise-induced dystonia and some insights into pathogenesis.
Auteurs : Michael H. Barnett [Royaume-Uni] ; Paul R. Jarman ; Simon J R. Heales ; Kailash P. BhatiaSource :
- Movement disorders : official journal of the Movement Disorder Society [ 0885-3185 ] ; 2002.
English descriptors
- KwdEn :
- MESH :
- chemical , cerebrospinal fluid : Homovanillic Acid, Hydroxyindoleacetic Acid.
- chemical , physiology : Dopamine.
- diagnosis : Dystonia.
- physiology : Exercise, Synaptic Transmission.
- physiopathology : Dystonia.
- Adult, Humans, Male, Neurologic Examination.
Abstract
Cerebrospinal fluid (CSF) analysis of pterin and monamine metabolites was performed before and after an attack in a patient with paroxysmal exercise-induced dystonia. A twofold increase in CSF homovanillic acid and 5-hydroxyindoleacetic acid after an attack was measured. This finding lends support to the hypothesis that increased dopaminergic transmission contributes to the clinical features of the hyperkinetic movement disorders.
DOI: 10.1002/mds.10291
PubMed: 12465091
Affiliations:
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pubmed:12465091Le document en format XML
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Jarman</name></author><author><name sortKey="Heales, Simon J R" sort="Heales, Simon J R" uniqKey="Heales S" first="Simon J R" last="Heales">Simon J R. Heales</name></author><author><name sortKey="Bhatia, Kailash P" sort="Bhatia, Kailash P" uniqKey="Bhatia K" first="Kailash P" last="Bhatia">Kailash P. Bhatia</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2002">2002</date><idno type="RBID">pubmed:12465091</idno><idno type="pmid">12465091</idno><idno type="doi">10.1002/mds.10291</idno><idno type="wicri:Area/PubMed/Corpus">003888</idno><idno type="wicri:Area/PubMed/Curation">003888</idno><idno type="wicri:Area/PubMed/Checkpoint">003A78</idno><idno type="wicri:Area/Ncbi/Merge">000963</idno><idno type="wicri:Area/Ncbi/Curation">000963</idno><idno type="wicri:Area/Ncbi/Checkpoint">000963</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Further case of paroxysmal exercise-induced dystonia and some insights into pathogenesis.</title><author><name sortKey="Barnett, Michael H" sort="Barnett, Michael H" uniqKey="Barnett M" first="Michael H" last="Barnett">Michael H. Barnett</name><affiliation wicri:level="3"><nlm:affiliation>National Hospital for Neurology and Neurosurgery, Institute of Neurology, Queen Square, London, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>National Hospital for Neurology and Neurosurgery, Institute of Neurology, Queen Square, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Jarman, Paul R" sort="Jarman, Paul R" uniqKey="Jarman P" first="Paul R" last="Jarman">Paul R. Jarman</name></author><author><name sortKey="Heales, Simon J R" sort="Heales, Simon J R" uniqKey="Heales S" first="Simon J R" last="Heales">Simon J R. Heales</name></author><author><name sortKey="Bhatia, Kailash P" sort="Bhatia, Kailash P" uniqKey="Bhatia K" first="Kailash P" last="Bhatia">Kailash P. Bhatia</name></author></analytic><series><title level="j">Movement disorders : official journal of the Movement Disorder Society</title><idno type="ISSN">0885-3185</idno><imprint><date when="2002" type="published">2002</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term><term>Dopamine (physiology)</term><term>Dystonia (diagnosis)</term><term>Dystonia (physiopathology)</term><term>Exercise (physiology)</term><term>Homovanillic Acid (cerebrospinal fluid)</term><term>Humans</term><term>Hydroxyindoleacetic Acid (cerebrospinal fluid)</term><term>Male</term><term>Neurologic Examination</term><term>Synaptic Transmission (physiology)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="cerebrospinal fluid" xml:lang="en"><term>Homovanillic Acid</term><term>Hydroxyindoleacetic Acid</term></keywords><keywords scheme="MESH" type="chemical" qualifier="physiology" xml:lang="en"><term>Dopamine</term></keywords><keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Dystonia</term></keywords><keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Exercise</term><term>Synaptic Transmission</term></keywords><keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Dystonia</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adult</term><term>Humans</term><term>Male</term><term>Neurologic Examination</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Cerebrospinal fluid (CSF) analysis of pterin and monamine metabolites was performed before and after an attack in a patient with paroxysmal exercise-induced dystonia. A twofold increase in CSF homovanillic acid and 5-hydroxyindoleacetic acid after an attack was measured. This finding lends support to the hypothesis that increased dopaminergic transmission contributes to the clinical features of the hyperkinetic movement disorders.</div></front></TEI><affiliations><list><country><li>Royaume-Uni</li></country><region><li>Angleterre</li><li>Grand Londres</li></region><settlement><li>Londres</li></settlement></list><tree><noCountry><name sortKey="Bhatia, Kailash P" sort="Bhatia, Kailash P" uniqKey="Bhatia K" first="Kailash P" last="Bhatia">Kailash P. Bhatia</name><name sortKey="Heales, Simon J R" sort="Heales, Simon J R" uniqKey="Heales S" first="Simon J R" last="Heales">Simon J R. Heales</name><name sortKey="Jarman, Paul R" sort="Jarman, Paul R" uniqKey="Jarman P" first="Paul R" last="Jarman">Paul R. Jarman</name></noCountry><country name="Royaume-Uni"><region name="Angleterre"><name sortKey="Barnett, Michael H" sort="Barnett, Michael H" uniqKey="Barnett M" first="Michael H" last="Barnett">Michael H. Barnett</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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