CSF dopamine, serotonin, and biopterin metabolites in patients with restless legs syndrome.
Identifieur interne : 000432 ( Ncbi/Checkpoint ); précédent : 000431; suivant : 000433CSF dopamine, serotonin, and biopterin metabolites in patients with restless legs syndrome.
Auteurs : C J Earley [États-Unis] ; K. Hyland ; R P AllenSource :
- Movement disorders : official journal of the Movement Disorder Society [ 0885-3185 ] ; 2001.
English descriptors
- KwdEn :
- Age Factors, Biopterin (analogs & derivatives), Biopterin (cerebrospinal fluid), Brain (metabolism), Dopamine (cerebrospinal fluid), Female, Homovanillic Acid (cerebrospinal fluid), Humans, Hydroxyindoleacetic Acid (cerebrospinal fluid), Male, Middle Aged, Neopterin (cerebrospinal fluid), Restless Legs Syndrome (cerebrospinal fluid), Serotonin (cerebrospinal fluid), Spinal Cord (metabolism).
- MESH :
- chemical , analogs & derivatives : Biopterin.
- chemical , cerebrospinal fluid : Biopterin, Dopamine, Homovanillic Acid, Hydroxyindoleacetic Acid, Neopterin, Serotonin.
- cerebrospinal fluid : Restless Legs Syndrome.
- metabolism : Brain, Spinal Cord.
- Age Factors, Female, Humans, Male, Middle Aged.
Abstract
To evaluate the role of CNS dopaminergic systems in Restless Legs Syndrome (RLS), homovanillic acid (HVA), tetrahydrobiopterin (BH4), and neopterin (NEOP), were assayed in CSF from RLS patients. The serotonin metabolite, 5-hydroxyindoleacetic acid (5-HIAA), was also measured.
PubMed: 11215576
Affiliations:
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- to stream Ncbi, to step Curation: 000432
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pubmed:11215576Le document en format XML
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<author><name sortKey="Earley, C J" sort="Earley, C J" uniqKey="Earley C" first="C J" last="Earley">C J Earley</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Neurology, Johns Hopkins Bayview Medical Center, Baltimore, Maryland 21224, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Neurology, Johns Hopkins Bayview Medical Center, Baltimore, Maryland 21224</wicri:regionArea>
<wicri:noRegion>Maryland 21224</wicri:noRegion>
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<author><name sortKey="Hyland, K" sort="Hyland, K" uniqKey="Hyland K" first="K" last="Hyland">K. Hyland</name>
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<author><name sortKey="Allen, R P" sort="Allen, R P" uniqKey="Allen R" first="R P" last="Allen">R P Allen</name>
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<sourceDesc><biblStruct><analytic><title xml:lang="en">CSF dopamine, serotonin, and biopterin metabolites in patients with restless legs syndrome.</title>
<author><name sortKey="Earley, C J" sort="Earley, C J" uniqKey="Earley C" first="C J" last="Earley">C J Earley</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Neurology, Johns Hopkins Bayview Medical Center, Baltimore, Maryland 21224, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Neurology, Johns Hopkins Bayview Medical Center, Baltimore, Maryland 21224</wicri:regionArea>
<wicri:noRegion>Maryland 21224</wicri:noRegion>
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<author><name sortKey="Hyland, K" sort="Hyland, K" uniqKey="Hyland K" first="K" last="Hyland">K. Hyland</name>
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<author><name sortKey="Allen, R P" sort="Allen, R P" uniqKey="Allen R" first="R P" last="Allen">R P Allen</name>
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<series><title level="j">Movement disorders : official journal of the Movement Disorder Society</title>
<idno type="ISSN">0885-3185</idno>
<imprint><date when="2001" type="published">2001</date>
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<term>Biopterin (analogs & derivatives)</term>
<term>Biopterin (cerebrospinal fluid)</term>
<term>Brain (metabolism)</term>
<term>Dopamine (cerebrospinal fluid)</term>
<term>Female</term>
<term>Homovanillic Acid (cerebrospinal fluid)</term>
<term>Humans</term>
<term>Hydroxyindoleacetic Acid (cerebrospinal fluid)</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Neopterin (cerebrospinal fluid)</term>
<term>Restless Legs Syndrome (cerebrospinal fluid)</term>
<term>Serotonin (cerebrospinal fluid)</term>
<term>Spinal Cord (metabolism)</term>
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<keywords scheme="MESH" type="chemical" qualifier="analogs & derivatives" xml:lang="en"><term>Biopterin</term>
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<keywords scheme="MESH" type="chemical" qualifier="cerebrospinal fluid" xml:lang="en"><term>Biopterin</term>
<term>Dopamine</term>
<term>Homovanillic Acid</term>
<term>Hydroxyindoleacetic Acid</term>
<term>Neopterin</term>
<term>Serotonin</term>
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<keywords scheme="MESH" qualifier="cerebrospinal fluid" xml:lang="en"><term>Restless Legs Syndrome</term>
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<keywords scheme="MESH" qualifier="metabolism" xml:lang="en"><term>Brain</term>
<term>Spinal Cord</term>
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<keywords scheme="MESH" xml:lang="en"><term>Age Factors</term>
<term>Female</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
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<front><div type="abstract" xml:lang="en">To evaluate the role of CNS dopaminergic systems in Restless Legs Syndrome (RLS), homovanillic acid (HVA), tetrahydrobiopterin (BH4), and neopterin (NEOP), were assayed in CSF from RLS patients. The serotonin metabolite, 5-hydroxyindoleacetic acid (5-HIAA), was also measured.</div>
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<affiliations><list><country><li>États-Unis</li>
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<name sortKey="Hyland, K" sort="Hyland, K" uniqKey="Hyland K" first="K" last="Hyland">K. Hyland</name>
</noCountry>
<country name="États-Unis"><noRegion><name sortKey="Earley, C J" sort="Earley, C J" uniqKey="Earley C" first="C J" last="Earley">C J Earley</name>
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