Movement Disorders (revue)

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Meige syndrome: Neuropathology of a case

Identifieur interne : 009909 ( Main/Merge ); précédent : 009908; suivant : 009910

Meige syndrome: Neuropathology of a case

Auteurs : J. Kulisevsky [Espagne] ; M. J. Marti [Espagne] ; I. Ferrer [Espagne] ; Tolosa [Espagne]

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RBID : ISTEX:040C60953C1AE3B2A58BB8215A542C5C0FB34E89

English descriptors

Abstract

Primary Meige syndrome is a form of cranial dystonia of unknown cause. Only three postmortem studies have been reported, and the results of these studies have not been consistent. We have examined the brain of a 72‐year‐old man with typical primary Meige syndrome and found mild to moderate cell loss in the zona compacta of the substanita nigra, locus ceuleus, midbrain tectum, and dentate nucleus of the cerebellum. Also frequent lewy bodies were present in pigmented nuclei of the brainstem. No abnormalities were detected elsewhere. These pathological findings support the notion that brainstem pathology is important in the pathophysiology of cranial dystonia.

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DOI: 10.1002/mds.870030209

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ISTEX:040C60953C1AE3B2A58BB8215A542C5C0FB34E89

Le document en format XML

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