Meige syndrome: neuropathology of a case.
Identifieur interne : 004620 ( Ncbi/Checkpoint ); précédent : 004619; suivant : 004621Meige syndrome: neuropathology of a case.
Auteurs : J. Kulisevsky [Espagne] ; M J Marti ; I. Ferrer ; E. TolosaSource :
- Movement disorders : official journal of the Movement Disorder Society [ 0885-3185 ] ; 1988.
English descriptors
- KwdEn :
- MESH :
- etiology : Meige Syndrome.
- pathology : Basal Ganglia Diseases, Brain Stem, Meige Syndrome.
- physiopathology : Meige Syndrome.
- Aged, Humans, Male, Movement, Muscle Contraction.
Abstract
Primary Meige syndrome is a form of cranial dystonia of unknown cause. Only three postmortem studies have been reported, and the results of these studies have not been consistent. We have examined the brain of a 72-year-old man with typical primary Meige syndrome and found mild to moderate cell loss in the zona compacta of the substantia nigra, locus ceruleus, midbrain tectum, and dentate nucleus of the cerebellum. Also frequent Lewy bodies were present in pigmented nuclei of the brainstem. No abnormalities were detected elsewhere. These pathological findings support the notion that brainstem pathology is important in the pathophysiology of cranial dystonia.
DOI: 10.1002/mds.870030209
PubMed: 3221903
Affiliations:
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Ferrer</name></author><author><name sortKey="Tolosa, E" sort="Tolosa, E" uniqKey="Tolosa E" first="E" last="Tolosa">E. Tolosa</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="1988">1988</date><idno type="RBID">pubmed:3221903</idno><idno type="pmid">3221903</idno><idno type="doi">10.1002/mds.870030209</idno><idno type="wicri:Area/PubMed/Corpus">005011</idno><idno type="wicri:Area/PubMed/Curation">005011</idno><idno type="wicri:Area/PubMed/Checkpoint">005029</idno><idno type="wicri:Area/Ncbi/Merge">004620</idno><idno type="wicri:Area/Ncbi/Curation">004620</idno><idno type="wicri:Area/Ncbi/Checkpoint">004620</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Meige syndrome: neuropathology of a case.</title><author><name sortKey="Kulisevsky, J" sort="Kulisevsky, J" uniqKey="Kulisevsky J" first="J" last="Kulisevsky">J. Kulisevsky</name><affiliation wicri:level="3"><nlm:affiliation>Neurology Service, Hospital Clinic i Provincial, Faculty of Medicine, Barcelona, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Neurology Service, Hospital Clinic i Provincial, Faculty of Medicine, Barcelona</wicri:regionArea><placeName><settlement type="city">Barcelone</settlement><region nuts="2" type="region">Catalogne</region></placeName></affiliation></author><author><name sortKey="Marti, M J" sort="Marti, M J" uniqKey="Marti M" first="M J" last="Marti">M J Marti</name></author><author><name sortKey="Ferrer, I" sort="Ferrer, I" uniqKey="Ferrer I" first="I" last="Ferrer">I. Ferrer</name></author><author><name sortKey="Tolosa, E" sort="Tolosa, E" uniqKey="Tolosa E" first="E" last="Tolosa">E. Tolosa</name></author></analytic><series><title level="j">Movement disorders : official journal of the Movement Disorder Society</title><idno type="ISSN">0885-3185</idno><imprint><date when="1988" type="published">1988</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Aged</term><term>Basal Ganglia Diseases (pathology)</term><term>Brain Stem (pathology)</term><term>Humans</term><term>Male</term><term>Meige Syndrome (etiology)</term><term>Meige Syndrome (pathology)</term><term>Meige Syndrome (physiopathology)</term><term>Movement</term><term>Muscle Contraction</term></keywords><keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Meige Syndrome</term></keywords><keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Basal Ganglia Diseases</term><term>Brain Stem</term><term>Meige Syndrome</term></keywords><keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Meige Syndrome</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Aged</term><term>Humans</term><term>Male</term><term>Movement</term><term>Muscle Contraction</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Primary Meige syndrome is a form of cranial dystonia of unknown cause. Only three postmortem studies have been reported, and the results of these studies have not been consistent. We have examined the brain of a 72-year-old man with typical primary Meige syndrome and found mild to moderate cell loss in the zona compacta of the substantia nigra, locus ceruleus, midbrain tectum, and dentate nucleus of the cerebellum. Also frequent Lewy bodies were present in pigmented nuclei of the brainstem. No abnormalities were detected elsewhere. These pathological findings support the notion that brainstem pathology is important in the pathophysiology of cranial dystonia.</div></front></TEI><affiliations><list><country><li>Espagne</li></country><region><li>Catalogne</li></region><settlement><li>Barcelone</li></settlement></list><tree><noCountry><name sortKey="Ferrer, I" sort="Ferrer, I" uniqKey="Ferrer I" first="I" last="Ferrer">I. Ferrer</name><name sortKey="Marti, M J" sort="Marti, M J" uniqKey="Marti M" first="M J" last="Marti">M J Marti</name><name sortKey="Tolosa, E" sort="Tolosa, E" uniqKey="Tolosa E" first="E" last="Tolosa">E. Tolosa</name></noCountry><country name="Espagne"><region name="Catalogne"><name sortKey="Kulisevsky, J" sort="Kulisevsky, J" uniqKey="Kulisevsky J" first="J" last="Kulisevsky">J. Kulisevsky</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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