MovDisordV3, Main, Merge, bibRecord, 006E78

Impact of Huntington's Disease on quality of life

Identifieur interne : 006E78 ( Main/Merge ); précédent : 006E77; suivant : 006E79

Impact of Huntington's Disease on quality of life

Auteurs : D. I. Helder [Pays-Bas] ; A. A. Kaptein [Pays-Bas] ; G. M. J. Van Kempen [Pays-Bas] ; J. C. Van Houwelingen [Pays-Bas] ; R. A. C. Roos [Pays-Bas]

Source :

Movement disorders [ 0885-3185 ] ; 2001.

RBID : Pascal:01-0335232

Descripteurs français

Pascal (Inist)
- Chorée Huntington, Qualité vie, Sickness Impact Profile Gilson, Bien être psychologique, Effet psychologique, Psychométrie, Adulte.
Wicri :
- topic : Adulte.

English descriptors

KwdEn :
- Adult, Huntington disease, Psychological effect, Psychological well being, Psychometrics, Quality of life, Sickness Impact Profile Gilson.

Abstract

The purpose of this study was to systematically assess the impact of Huntington's disease (HD) on patients' health-related quality of life (QOL). Seventy-seven patients with a clinically confirmed diagnosis of HD were interviewed by means of the Sickness Impact Profile (SIP), Additional data were gathered on patients' motor performance by means of the motor section of the Unified Huntington Disease Rating Scale (UHDRS), and cognitive performance by means of the Mini-Mental State (MMS). Patients had high scores on the SIP subscales, indicating moderate to severe functional impairment. Total Motor Score (TMS), MMS scores, and the duration of HD were significantly correlated with patients' scores on the SIP, and predicted a significant amount of variance of the Physical Dimension of the SIP, hut not of the Psychosocial Dimension. We conclude that HD has a great impact on patients' physical and psychosocial well-being, the latter being more severely affected. Implications for further research and clinical practice are discussed.

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Pascal:01-0335232

Le document en format XML

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<front><div type="abstract" xml:lang="en">The purpose of this study was to systematically assess the impact of Huntington's disease (HD) on patients' health-related quality of life (QOL). Seventy-seven patients with a clinically confirmed diagnosis of HD were interviewed by means of the Sickness Impact Profile (SIP), Additional data were gathered on patients' motor performance by means of the motor section of the Unified Huntington Disease Rating Scale (UHDRS), and cognitive performance by means of the Mini-Mental State (MMS). Patients had high scores on the SIP subscales, indicating moderate to severe functional impairment. Total Motor Score (TMS), MMS scores, and the duration of HD were significantly correlated with patients' scores on the SIP, and predicted a significant amount of variance of the Physical Dimension of the SIP, hut not of the Psychosocial Dimension. We conclude that HD has a great impact on patients' physical and psychosocial well-being, the latter being more severely affected. Implications for further research and clinical practice are discussed.</div>
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	Movement Disorders (revue)
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Movement Disorders (revue)

Impact of Huntington's Disease on quality of life

Impact of Huntington's Disease on quality of life

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri