MovDisordV3, Main, Merge, bibRecord, 006673

Quality of life in stiff-person syndrome

Identifieur interne : 006673 ( Main/Merge ); précédent : 006672; suivant : 006674

Quality of life in stiff-person syndrome

Auteurs : Willibald Gerschlager [Royaume-Uni, Autriche] ; Anette Schrag [Royaume-Uni] ; Peter Brown [Royaume-Uni]

Source :

Movement disorders [ 0885-3185 ] ; 2002.

RBID : Pascal:02-0584506

Descripteurs français

Pascal (Inist)
- Homme raide syndrome, Qualité vie, Exploration, Homme.
Wicri :
- topic : Homme.

English descriptors

KwdEn :
- Exploration, Human, Quality of life, Stiff man syndrome.

Abstract

Stiff-person syndrome (SPS) is a rare, chronic disorder characterized by painful spasm and stiffness. We investigated the quality of life (QoL) in SPS patients, and identified factors associated with impairment in patients' QoL. Twenty-four SPS patients (10 men, 14 women; mean age ± S.D., 52.6 ± 9.5 years) completed the medical outcomes study Short Form health survey (SF-36), the Beck Depression Inventory (BDI), and a questionnaire asking for sociodemographic and clinical details. Extent of the disease was assessed using a distribution of stiffness score. SPS patients showed markedly reduced mean scores for all dimensions of the SF-36 when compared to norms from the general population of the United Kingdom. QoL scores showed a strong correlation with the extent of the disease. Depression was a common finding; 14 of 24 patients had depressive symptoms as evidenced by the BDI. There was a significant and strong correlation between the BDI score and several SF-36 subscores. This is the first study to address QoL in patients with SPS. We have shown that SPS has a significant impact on patients' reported QoL. The association between depression and QoL highlights the importance of recognizing and treating depression in SPS.

Links toward previous steps (curation, corpus...)

to stream PascalFrancis, to step Corpus: 002615
to stream PascalFrancis, to step Curation: 000706
to stream PascalFrancis, to step Checkpoint: 002634

Links to Exploration step

Pascal:02-0584506

Le document en format XML

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<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a">Quality of life in stiff-person syndrome</title>
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<front><div type="abstract" xml:lang="en">Stiff-person syndrome (SPS) is a rare, chronic disorder characterized by painful spasm and stiffness. We investigated the quality of life (QoL) in SPS patients, and identified factors associated with impairment in patients' QoL. Twenty-four SPS patients (10 men, 14 women; mean age ± S.D., 52.6 ± 9.5 years) completed the medical outcomes study Short Form health survey (SF-36), the Beck Depression Inventory (BDI), and a questionnaire asking for sociodemographic and clinical details. Extent of the disease was assessed using a distribution of stiffness score. SPS patients showed markedly reduced mean scores for all dimensions of the SF-36 when compared to norms from the general population of the United Kingdom. QoL scores showed a strong correlation with the extent of the disease. Depression was a common finding; 14 of 24 patients had depressive symptoms as evidenced by the BDI. There was a significant and strong correlation between the BDI score and several SF-36 subscores. This is the first study to address QoL in patients with SPS. We have shown that SPS has a significant impact on patients' reported QoL. The association between depression and QoL highlights the importance of recognizing and treating depression in SPS.</div>
</front>
</TEI>
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	Movement Disorders (revue)
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Movement Disorders (revue)

Quality of life in stiff-person syndrome

Quality of life in stiff-person syndrome

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri