MovDisordV3, Main, Merge, bibRecord, 006672

Quality of life outcomes following surgical treatment of Parkinson's disease

Identifieur interne : 006672 ( Main/Merge ); précédent : 006671; suivant : 006673

Quality of life outcomes following surgical treatment of Parkinson's disease

Auteurs : Alastair Gray [Royaume-Uni] ; Lain Mcnamara [Royaume-Uni] ; Tipu Aziz [Royaume-Uni] ; Ralph Gregory [Royaume-Uni] ; Peter Bain [Royaume-Uni] ; Joanna Wilson [Royaume-Uni] ; Richard Scott [Royaume-Uni]

Source :

Movement disorders [ 0885-3185 ] ; 2002.

RBID : Pascal:02-0204554

Descripteurs français

Pascal (Inist)
- Parkinson maladie, Qualité vie, Exérèse, Thalamus, Pallidum, Noyau sousthalamique, Stimulus électrique, Evolution, Traitement, Pronostic, Psychométrie, Adulte.
Wicri :
- topic : Adulte.

English descriptors

KwdEn :
- Adult, Electrical stimulus, Evolution, Exeresis, Pallidum, Parkinson disease, Prognosis, Psychometrics, Quality of life, Subthalamic nucleus, Thalamus, Treatment.

Abstract

We assessed the impact of surgical treatment of Parkinson's disease on quality of life using generic quality of life instruments and utility scores. The Medical Outcomes Study short form health survey SF-36 and Parkinson's Disease Questionnaire PDQ-39 were used before and 3-6 months after surgery to assess quality of life, and the results were converted into utility valuations. Ninety-seven patients were studied; 33 underwent unilateral thalamotomy, 33 unilateral pallidotomy, 20 bilateral pallidotomy, six subthalamic nucleus (STN) lesions, four mixed lesions and in one case bilateral STN stimulation. All dimensions of the SF-36 except role mental and mental health showed statistically significant improvement following surgery. The PDQ-39 recorded significant improvements in the mobility, stigma, and bodily discomfort dimensions. The rating scale and time trade-off scales showed statistically significant gains in utility of 8% and 3%, respectively. Gains were particularly marked in the bilateral pallidotomy group. Differences in patient characteristics and selection made direct comparisons between procedures unreliable. Quality of life in patients with advanced Parkinson's disease is amenable to measurement; such measurement provides tentative evidence of significant gains in quality of life following some neurosurgical procedures.

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Pascal:02-0204554

Le document en format XML

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<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a">Quality of life outcomes following surgical treatment of Parkinson's disease</title>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term>
<term>Electrical stimulus</term>
<term>Evolution</term>
<term>Exeresis</term>
<term>Pallidum</term>
<term>Parkinson disease</term>
<term>Prognosis</term>
<term>Psychometrics</term>
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<term>Noyau sousthalamique</term>
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<front><div type="abstract" xml:lang="en">We assessed the impact of surgical treatment of Parkinson's disease on quality of life using generic quality of life instruments and utility scores. The Medical Outcomes Study short form health survey SF-36 and Parkinson's Disease Questionnaire PDQ-39 were used before and 3-6 months after surgery to assess quality of life, and the results were converted into utility valuations. Ninety-seven patients were studied; 33 underwent unilateral thalamotomy, 33 unilateral pallidotomy, 20 bilateral pallidotomy, six subthalamic nucleus (STN) lesions, four mixed lesions and in one case bilateral STN stimulation. All dimensions of the SF-36 except role mental and mental health showed statistically significant improvement following surgery. The PDQ-39 recorded significant improvements in the mobility, stigma, and bodily discomfort dimensions. The rating scale and time trade-off scales showed statistically significant gains in utility of 8% and 3%, respectively. Gains were particularly marked in the bilateral pallidotomy group. Differences in patient characteristics and selection made direct comparisons between procedures unreliable. Quality of life in patients with advanced Parkinson's disease is amenable to measurement; such measurement provides tentative evidence of significant gains in quality of life following some neurosurgical procedures.</div>
</front>
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<tree><country name="Royaume-Uni"><region name="Angleterre"><name sortKey="Gray, Alastair" sort="Gray, Alastair" uniqKey="Gray A" first="Alastair" last="Gray">Alastair Gray</name>
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<name sortKey="Aziz, Tipu" sort="Aziz, Tipu" uniqKey="Aziz T" first="Tipu" last="Aziz">Tipu Aziz</name>
<name sortKey="Bain, Peter" sort="Bain, Peter" uniqKey="Bain P" first="Peter" last="Bain">Peter Bain</name>
<name sortKey="Gregory, Ralph" sort="Gregory, Ralph" uniqKey="Gregory R" first="Ralph" last="Gregory">Ralph Gregory</name>
<name sortKey="Mcnamara, Lain" sort="Mcnamara, Lain" uniqKey="Mcnamara L" first="Lain" last="Mcnamara">Lain Mcnamara</name>
<name sortKey="Scott, Richard" sort="Scott, Richard" uniqKey="Scott R" first="Richard" last="Scott">Richard Scott</name>
<name sortKey="Scott, Richard" sort="Scott, Richard" uniqKey="Scott R" first="Richard" last="Scott">Richard Scott</name>
<name sortKey="Wilson, Joanna" sort="Wilson, Joanna" uniqKey="Wilson J" first="Joanna" last="Wilson">Joanna Wilson</name>
<name sortKey="Wilson, Joanna" sort="Wilson, Joanna" uniqKey="Wilson J" first="Joanna" last="Wilson">Joanna Wilson</name>
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</record>

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	Movement Disorders (revue)
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Movement Disorders (revue)

Quality of life outcomes following surgical treatment of Parkinson's disease

Quality of life outcomes following surgical treatment of Parkinson's disease

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri