Treatment of Sydenham chorea with corticosteroids
Identifieur interne : 005B30 ( Main/Merge ); précédent : 005B29; suivant : 005B31Treatment of Sydenham chorea with corticosteroids
Auteurs : Francisco Cardoso [Brésil] ; Débora Maia [Brésil] ; Mauro César Q. S. Cunningham [Brésil] ; Guilherme Valença [Brésil]Source :
- Movement Disorders [ 0885-3185 ] ; 2003-11.
English descriptors
- KwdEn :
- Adolescent, Adult, Anti-Inflammatory Agents (administration & dosage), Anti-Inflammatory Agents (therapeutic use), Child, Chorea (drug therapy), Drug Administration Schedule, Female, Follow-Up Studies, Humans, Injections, Intravenous, Male, Methylprednisolone (administration & dosage), Methylprednisolone (therapeutic use), Middle Aged, Sydenham chorea, Treatment Outcome, anti‐basal ganglia antibody, chorea, methyl‐prednisolone, prednisone, rheumatic fever, steroids.
- MESH :
- chemical , administration & dosage : Anti-Inflammatory Agents, Methylprednisolone.
- chemical , therapeutic use : Anti-Inflammatory Agents, Methylprednisolone.
- drug therapy : Chorea.
- Adolescent, Adult, Child, Drug Administration Schedule, Female, Follow-Up Studies, Humans, Injections, Intravenous, Male, Middle Aged, Treatment Outcome.
Abstract
Despite treatment with valproic acid and neuroleptics, a significant proportion of patients with Sydenham chorea (SC) remain with chorea. We evaluated the effect of intravenous methyl‐prednisolone followed by oral prednisone in patients with SC refractory to conventional treatment. Patients were enrolled in the study if they failed to improve with conventional treatment, despite the development of side effects. Chorea was rated on a 0 to 4 score. Five patients, 3 of them women, were included in the study. The median pretreatment rating score of the chorea was 3 (range, 3–4) and dropped to 1 (range, 0–2) after a median follow‐up of 7 months (range, 3–7 months). Two patients developed Cushing syndrome. Our data suggest that intravenous methyl‐prednisolone followed by oral prednisone is an effective and well‐tolerated treatment of refractory SC. © 2003 Movement Disorder Society
Url:
DOI: 10.1002/mds.10521
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ISTEX:D67A21717E49D74965DBEE2DD81CB0DF71E70486Le document en format XML
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Cunningham</name></author><author><name sortKey="Valenca, Guilherme" sort="Valenca, Guilherme" uniqKey="Valenca G" first="Guilherme" last="Valença">Guilherme Valença</name></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:D67A21717E49D74965DBEE2DD81CB0DF71E70486</idno><date when="2003" year="2003">2003</date><idno type="doi">10.1002/mds.10521</idno><idno type="url">https://api.istex.fr/document/D67A21717E49D74965DBEE2DD81CB0DF71E70486/fulltext/pdf</idno><idno type="wicri:Area/Istex/Corpus">003034</idno><idno type="wicri:Area/Istex/Curation">003034</idno><idno type="wicri:Area/Istex/Checkpoint">002837</idno><idno type="wicri:doubleKey">0885-3185:2003:Cardoso F:treatment:of:sydenham</idno><idno type="wicri:source">PubMed</idno><idno type="RBID">pubmed:14639684</idno><idno type="wicri:Area/PubMed/Corpus">003625</idno><idno type="wicri:Area/PubMed/Curation">003625</idno><idno type="wicri:Area/PubMed/Checkpoint">003604</idno><idno type="wicri:Area/Ncbi/Merge">000C39</idno><idno type="wicri:Area/Ncbi/Curation">000C39</idno><idno type="wicri:Area/Ncbi/Checkpoint">000C39</idno><idno type="wicri:doubleKey">0885-3185:2003:Cardoso F:treatment:of:sydenham</idno><idno type="wicri:Area/Main/Merge">005B30</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Treatment of Sydenham chorea with corticosteroids</title><author><name sortKey="Cardoso, Francisco" sort="Cardoso, Francisco" uniqKey="Cardoso F" first="Francisco" last="Cardoso">Francisco Cardoso</name><affiliation wicri:level="4"><country xml:lang="fr">Brésil</country><wicri:regionArea>Movement Disorders Clinic, Hospital das Clínicas, Universidade Federal de Minas Gerais, Belo Horizonte, MG</wicri:regionArea><placeName><region type="state">Minas Gerais</region><settlement type="city">Belo Horizonte</settlement></placeName><orgName type="university">Université fédérale du Minas Gerais</orgName></affiliation></author><author><name sortKey="Maia, Debora" sort="Maia, Debora" uniqKey="Maia D" first="Débora" last="Maia">Débora Maia</name><affiliation wicri:level="4"><country xml:lang="fr">Brésil</country><wicri:regionArea>Movement Disorders Clinic, Hospital das Clínicas, Universidade Federal de Minas Gerais, Belo Horizonte, MG</wicri:regionArea><placeName><region type="state">Minas Gerais</region><settlement type="city">Belo Horizonte</settlement></placeName><orgName type="university">Université fédérale du Minas Gerais</orgName></affiliation></author><author><name sortKey="Cunningham, Mauro Cesar Q S" sort="Cunningham, Mauro Cesar Q S" uniqKey="Cunningham M" first="Mauro César Q. 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Cunningham</name><affiliation wicri:level="4"><country xml:lang="fr">Brésil</country><wicri:regionArea>Movement Disorders Clinic, Hospital das Clínicas, Universidade Federal de Minas Gerais, Belo Horizonte, MG</wicri:regionArea><placeName><region type="state">Minas Gerais</region><settlement type="city">Belo Horizonte</settlement></placeName><orgName type="university">Université fédérale du Minas Gerais</orgName></affiliation></author><author><name sortKey="Valenca, Guilherme" sort="Valenca, Guilherme" uniqKey="Valenca G" first="Guilherme" last="Valença">Guilherme Valença</name><affiliation wicri:level="4"><country xml:lang="fr">Brésil</country><wicri:regionArea>Movement Disorders Clinic, Hospital das Clínicas, Universidade Federal de Minas Gerais, Belo Horizonte, MG</wicri:regionArea><placeName><region type="state">Minas Gerais</region><settlement type="city">Belo Horizonte</settlement></placeName><orgName type="university">Université fédérale du Minas Gerais</orgName></affiliation></author></analytic><monogr></monogr><series><title level="j">Movement Disorders</title><title level="j" type="sub">Official Journal of the Movement Disorder Society</title><title level="j" type="abbrev">Mov. Disord.</title><idno type="ISSN">0885-3185</idno><idno type="eISSN">1531-8257</idno><imprint><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><pubPlace>Hoboken</pubPlace><date type="published" when="2003-11">2003-11</date><biblScope unit="vol">18</biblScope><biblScope unit="issue">11</biblScope><biblScope unit="page" from="1374">1374</biblScope><biblScope unit="page" to="1377">1377</biblScope></imprint><idno type="ISSN">0885-3185</idno></series><idno type="istex">D67A21717E49D74965DBEE2DD81CB0DF71E70486</idno><idno type="DOI">10.1002/mds.10521</idno><idno type="ArticleID">MDS10521</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0885-3185</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adolescent</term><term>Adult</term><term>Anti-Inflammatory Agents (administration & dosage)</term><term>Anti-Inflammatory Agents (therapeutic use)</term><term>Child</term><term>Chorea (drug therapy)</term><term>Drug Administration Schedule</term><term>Female</term><term>Follow-Up Studies</term><term>Humans</term><term>Injections, Intravenous</term><term>Male</term><term>Methylprednisolone (administration & dosage)</term><term>Methylprednisolone (therapeutic use)</term><term>Middle Aged</term><term>Sydenham chorea</term><term>Treatment Outcome</term><term>anti‐basal ganglia antibody</term><term>chorea</term><term>methyl‐prednisolone</term><term>prednisone</term><term>rheumatic fever</term><term>steroids</term></keywords><keywords scheme="MESH" type="chemical" qualifier="administration & dosage" xml:lang="en"><term>Anti-Inflammatory Agents</term><term>Methylprednisolone</term></keywords><keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Anti-Inflammatory Agents</term><term>Methylprednisolone</term></keywords><keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Chorea</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adolescent</term><term>Adult</term><term>Child</term><term>Drug Administration Schedule</term><term>Female</term><term>Follow-Up Studies</term><term>Humans</term><term>Injections, Intravenous</term><term>Male</term><term>Middle Aged</term><term>Treatment Outcome</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Despite treatment with valproic acid and neuroleptics, a significant proportion of patients with Sydenham chorea (SC) remain with chorea. We evaluated the effect of intravenous methyl‐prednisolone followed by oral prednisone in patients with SC refractory to conventional treatment. Patients were enrolled in the study if they failed to improve with conventional treatment, despite the development of side effects. Chorea was rated on a 0 to 4 score. Five patients, 3 of them women, were included in the study. The median pretreatment rating score of the chorea was 3 (range, 3–4) and dropped to 1 (range, 0–2) after a median follow‐up of 7 months (range, 3–7 months). Two patients developed Cushing syndrome. Our data suggest that intravenous methyl‐prednisolone followed by oral prednisone is an effective and well‐tolerated treatment of refractory SC. © 2003 Movement Disorder Society</div></front></TEI><double doi="10.1002/mds.10521"><ISTEX><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Treatment of Sydenham chorea with corticosteroids</title><author><name sortKey="Cardoso, Francisco" sort="Cardoso, Francisco" uniqKey="Cardoso F" first="Francisco" last="Cardoso">Francisco Cardoso</name></author><author><name sortKey="Maia, Debora" sort="Maia, Debora" uniqKey="Maia D" first="Débora" last="Maia">Débora Maia</name></author><author><name sortKey="Cunningham, Mauro Cesar Q S" sort="Cunningham, Mauro Cesar Q S" uniqKey="Cunningham M" first="Mauro César Q. S." last="Cunningham">Mauro César Q. S. Cunningham</name></author><author><name sortKey="Valenca, Guilherme" sort="Valenca, Guilherme" uniqKey="Valenca G" first="Guilherme" last="Valença">Guilherme Valença</name></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:D67A21717E49D74965DBEE2DD81CB0DF71E70486</idno><date when="2003" year="2003">2003</date><idno type="doi">10.1002/mds.10521</idno><idno type="url">https://api.istex.fr/document/D67A21717E49D74965DBEE2DD81CB0DF71E70486/fulltext/pdf</idno><idno type="wicri:Area/Istex/Corpus">003034</idno><idno type="wicri:Area/Istex/Curation">003034</idno><idno type="wicri:Area/Istex/Checkpoint">002837</idno><idno type="wicri:doubleKey">0885-3185:2003:Cardoso F:treatment:of:sydenham</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Treatment of Sydenham chorea with corticosteroids</title><author><name sortKey="Cardoso, Francisco" sort="Cardoso, Francisco" uniqKey="Cardoso F" first="Francisco" last="Cardoso">Francisco Cardoso</name><affiliation wicri:level="4"><country xml:lang="fr">Brésil</country><wicri:regionArea>Movement Disorders Clinic, Hospital das Clínicas, Universidade Federal de Minas Gerais, Belo Horizonte, MG</wicri:regionArea><placeName><region type="state">Minas Gerais</region><settlement type="city">Belo Horizonte</settlement></placeName><orgName type="university">Université fédérale du Minas Gerais</orgName></affiliation></author><author><name sortKey="Maia, Debora" sort="Maia, Debora" uniqKey="Maia D" first="Débora" last="Maia">Débora Maia</name><affiliation wicri:level="4"><country xml:lang="fr">Brésil</country><wicri:regionArea>Movement Disorders Clinic, Hospital das Clínicas, Universidade Federal de Minas Gerais, Belo Horizonte, MG</wicri:regionArea><placeName><region type="state">Minas Gerais</region><settlement type="city">Belo Horizonte</settlement></placeName><orgName type="university">Université fédérale du Minas Gerais</orgName></affiliation></author><author><name sortKey="Cunningham, Mauro Cesar Q S" sort="Cunningham, Mauro Cesar Q S" uniqKey="Cunningham M" first="Mauro César Q. S." last="Cunningham">Mauro César Q. S. Cunningham</name><affiliation wicri:level="4"><country xml:lang="fr">Brésil</country><wicri:regionArea>Movement Disorders Clinic, Hospital das Clínicas, Universidade Federal de Minas Gerais, Belo Horizonte, MG</wicri:regionArea><placeName><region type="state">Minas Gerais</region><settlement type="city">Belo Horizonte</settlement></placeName><orgName type="university">Université fédérale du Minas Gerais</orgName></affiliation></author><author><name sortKey="Valenca, Guilherme" sort="Valenca, Guilherme" uniqKey="Valenca G" first="Guilherme" last="Valença">Guilherme Valença</name><affiliation wicri:level="4"><country xml:lang="fr">Brésil</country><wicri:regionArea>Movement Disorders Clinic, Hospital das Clínicas, Universidade Federal de Minas Gerais, Belo Horizonte, MG</wicri:regionArea><placeName><region type="state">Minas Gerais</region><settlement type="city">Belo Horizonte</settlement></placeName><orgName type="university">Université fédérale du Minas Gerais</orgName></affiliation></author></analytic><monogr></monogr><series><title level="j">Movement Disorders</title><title level="j" type="sub">Official Journal of the Movement Disorder Society</title><title level="j" type="abbrev">Mov. Disord.</title><idno type="ISSN">0885-3185</idno><idno type="eISSN">1531-8257</idno><imprint><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><pubPlace>Hoboken</pubPlace><date type="published" when="2003-11">2003-11</date><biblScope unit="vol">18</biblScope><biblScope unit="issue">11</biblScope><biblScope unit="page" from="1374">1374</biblScope><biblScope unit="page" to="1377">1377</biblScope></imprint><idno type="ISSN">0885-3185</idno></series><idno type="istex">D67A21717E49D74965DBEE2DD81CB0DF71E70486</idno><idno type="DOI">10.1002/mds.10521</idno><idno type="ArticleID">MDS10521</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0885-3185</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Sydenham chorea</term><term>anti‐basal ganglia antibody</term><term>chorea</term><term>methyl‐prednisolone</term><term>prednisone</term><term>rheumatic fever</term><term>steroids</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Despite treatment with valproic acid and neuroleptics, a significant proportion of patients with Sydenham chorea (SC) remain with chorea. We evaluated the effect of intravenous methyl‐prednisolone followed by oral prednisone in patients with SC refractory to conventional treatment. Patients were enrolled in the study if they failed to improve with conventional treatment, despite the development of side effects. Chorea was rated on a 0 to 4 score. Five patients, 3 of them women, were included in the study. The median pretreatment rating score of the chorea was 3 (range, 3–4) and dropped to 1 (range, 0–2) after a median follow‐up of 7 months (range, 3–7 months). Two patients developed Cushing syndrome. Our data suggest that intravenous methyl‐prednisolone followed by oral prednisone is an effective and well‐tolerated treatment of refractory SC. © 2003 Movement Disorder Society</div></front></TEI></ISTEX><PubMed><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Treatment of Sydenham chorea with corticosteroids.</title><author><name sortKey="Cardoso, Francisco" sort="Cardoso, Francisco" uniqKey="Cardoso F" first="Francisco" last="Cardoso">Francisco Cardoso</name><affiliation wicri:level="4"><nlm:affiliation>Movement Disorders Clinic, Hospital das Clínicas, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil. cardosof@metalink.com.br</nlm:affiliation><country xml:lang="fr">Brésil</country><wicri:regionArea>Movement Disorders Clinic, Hospital das Clínicas, Universidade Federal de Minas Gerais, Belo Horizonte, MG</wicri:regionArea><placeName><region type="state">Minas Gerais</region><settlement type="city">Belo Horizonte</settlement></placeName><orgName type="university">Université fédérale du Minas Gerais</orgName></affiliation></author><author><name sortKey="Maia, Debora" sort="Maia, Debora" uniqKey="Maia D" first="Débora" last="Maia">Débora Maia</name></author><author><name sortKey="Cunningham, Mauro Cesar Q S" sort="Cunningham, Mauro Cesar Q S" uniqKey="Cunningham M" first="Mauro César Q S" last="Cunningham">Mauro César Q S. Cunningham</name></author><author><name sortKey="Valenca, Guilherme" sort="Valenca, Guilherme" uniqKey="Valenca G" first="Guilherme" last="Valença">Guilherme Valença</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2003">2003</date><idno type="RBID">pubmed:14639684</idno><idno type="pmid">14639684</idno><idno type="doi">10.1002/mds.10521</idno><idno type="wicri:Area/PubMed/Corpus">003625</idno><idno type="wicri:Area/PubMed/Curation">003625</idno><idno type="wicri:Area/PubMed/Checkpoint">003604</idno><idno type="wicri:Area/Ncbi/Merge">000C39</idno><idno type="wicri:Area/Ncbi/Curation">000C39</idno><idno type="wicri:Area/Ncbi/Checkpoint">000C39</idno><idno type="wicri:doubleKey">0885-3185:2003:Cardoso F:treatment:of:sydenham</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Treatment of Sydenham chorea with corticosteroids.</title><author><name sortKey="Cardoso, Francisco" sort="Cardoso, Francisco" uniqKey="Cardoso F" first="Francisco" last="Cardoso">Francisco Cardoso</name><affiliation wicri:level="4"><nlm:affiliation>Movement Disorders Clinic, Hospital das Clínicas, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil. cardosof@metalink.com.br</nlm:affiliation><country xml:lang="fr">Brésil</country><wicri:regionArea>Movement Disorders Clinic, Hospital das Clínicas, Universidade Federal de Minas Gerais, Belo Horizonte, MG</wicri:regionArea><placeName><region type="state">Minas Gerais</region><settlement type="city">Belo Horizonte</settlement></placeName><orgName type="university">Université fédérale du Minas Gerais</orgName></affiliation></author><author><name sortKey="Maia, Debora" sort="Maia, Debora" uniqKey="Maia D" first="Débora" last="Maia">Débora Maia</name></author><author><name sortKey="Cunningham, Mauro Cesar Q S" sort="Cunningham, Mauro Cesar Q S" uniqKey="Cunningham M" first="Mauro César Q S" last="Cunningham">Mauro César Q S. Cunningham</name></author><author><name sortKey="Valenca, Guilherme" sort="Valenca, Guilherme" uniqKey="Valenca G" first="Guilherme" last="Valença">Guilherme Valença</name></author></analytic><series><title level="j">Movement disorders : official journal of the Movement Disorder Society</title><idno type="ISSN">0885-3185</idno><imprint><date when="2003" type="published">2003</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adolescent</term><term>Adult</term><term>Anti-Inflammatory Agents (administration & dosage)</term><term>Anti-Inflammatory Agents (therapeutic use)</term><term>Child</term><term>Chorea (drug therapy)</term><term>Drug Administration Schedule</term><term>Female</term><term>Follow-Up Studies</term><term>Humans</term><term>Injections, Intravenous</term><term>Male</term><term>Methylprednisolone (administration & dosage)</term><term>Methylprednisolone (therapeutic use)</term><term>Middle Aged</term><term>Treatment Outcome</term></keywords><keywords scheme="MESH" type="chemical" qualifier="administration & dosage" xml:lang="en"><term>Anti-Inflammatory Agents</term><term>Methylprednisolone</term></keywords><keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Anti-Inflammatory Agents</term><term>Methylprednisolone</term></keywords><keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Chorea</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adolescent</term><term>Adult</term><term>Child</term><term>Drug Administration Schedule</term><term>Female</term><term>Follow-Up Studies</term><term>Humans</term><term>Injections, Intravenous</term><term>Male</term><term>Middle Aged</term><term>Treatment Outcome</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Despite treatment with valproic acid and neuroleptics, a significant proportion of patients with Sydenham chorea (SC) remain with chorea. We evaluated the effect of intravenous methyl-prednisolone followed by oral prednisone in patients with SC refractory to conventional treatment. Patients were enrolled in the study if they failed to improve with conventional treatment, despite the development of side effects. Chorea was rated on a 0 to 4 score. Five patients, 3 of them women, were included in the study. The median pretreatment rating score of the chorea was 3 (range, 3-4) and dropped to 1 (range, 0-2) after a median follow-up of 7 months (range, 3-7 months). Two patients developed Cushing syndrome. Our data suggest that intravenous methyl-prednisolone followed by oral prednisone is an effective and well-tolerated treatment of refractory SC.</div></front></TEI></PubMed></double></record>Pour manipuler ce document sous Unix (Dilib)
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