Impact of the motor complications of Parkinson's disease on the quality of life
Identifieur interne : 005302 ( Main/Merge ); précédent : 005301; suivant : 005303Impact of the motor complications of Parkinson's disease on the quality of life
Auteurs : Stéphane Chapuis [France] ; Lemlih Ouchchane [France] ; Olivier Metz [France] ; Laurent Gerbaud [France] ; Franck Durif [France]Source :
- Movement disorders [ 0885-3185 ] ; 2005.
Descripteurs français
- Pascal (Inist)
English descriptors
Abstract
The impact of motor complications of Parkinson's disease (PD), especially levodopa-induced dyskinesias, on quality of life (QL) was studied in 143 patients with PD. All were evaluated on the Hoehn and Yahr (H&Y) scale, and the Motor part of the Unified Parkinson's Disease Rating Scale (UPDRS). Motor complications were analyzed using the UPDRS Parts IVA and IVB and the Abnormal Involuntary Movement Scale. A specific Parkinson's disease quality of life questionnaire (39-item version, PDQ-39) was used. Motor complications significantly worsened the PDQ-39 Summary Index (PDQ-SI) of patients with PD. The dimensions of Mobility, Activities of Daily Living, Stigma, and Communication were the most strongly affected. "Peak dose" dyskinesia decreased Mobility, Emotional Well-Being, and Cognition, whereas biphasic dyskinesia affected Mobility, Stigma, Communication, and Activities of Daily Living. Morning akinesia, end-of-dose fluctuations, and "unpredictable offs" decreased QL on the dimensions of Mobility, Activities of Daily Living, Stigma, and Communication. Nocturnal akinesia led to a deterioration of all dimensions of the PDQ-39. Thus, motor complications and especially nocturnal akinesia and biphasic dyskinesias worsened the QL of PD patients.
Links toward previous steps (curation, corpus...)
- to stream PascalFrancis, to step Corpus: 001F58
- to stream PascalFrancis, to step Curation: 000D63
- to stream PascalFrancis, to step Checkpoint: 001E24
Links to Exploration step
Pascal:05-0151002Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en" level="a">Impact of the motor complications of Parkinson's disease on the quality of life</title><author><name sortKey="Chapuis, Stephane" sort="Chapuis, Stephane" uniqKey="Chapuis S" first="Stéphane" last="Chapuis">Stéphane Chapuis</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Service de Neurologie, Centre Hospitalier</s1><s2>Vichy</s2><s3>FRA</s3><sZ>1 aut.</sZ></inist:fA14><country>France</country><placeName><settlement type="city">Vichy</settlement></placeName></affiliation></author><author><name sortKey="Ouchchane, Lemlih" sort="Ouchchane, Lemlih" uniqKey="Ouchchane L" first="Lemlih" last="Ouchchane">Lemlih Ouchchane</name><affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Service d'épidémiologie et d'économie de la santé</s1><s2>Clermont-Ferrand</s2><s3>FRA</s3><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ></inist:fA14><country>France</country><placeName><settlement type="city">Clermont-Ferrand</settlement></placeName></affiliation></author><author><name sortKey="Metz, Olivier" sort="Metz, Olivier" uniqKey="Metz O" first="Olivier" last="Metz">Olivier Metz</name><affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Service d'épidémiologie et d'économie de la santé</s1><s2>Clermont-Ferrand</s2><s3>FRA</s3><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ></inist:fA14><country>France</country><placeName><settlement type="city">Clermont-Ferrand</settlement></placeName></affiliation></author><author><name sortKey="Gerbaud, Laurent" sort="Gerbaud, Laurent" uniqKey="Gerbaud L" first="Laurent" last="Gerbaud">Laurent Gerbaud</name><affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Service d'épidémiologie et d'économie de la santé</s1><s2>Clermont-Ferrand</s2><s3>FRA</s3><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ></inist:fA14><country>France</country><placeName><settlement type="city">Clermont-Ferrand</settlement></placeName></affiliation></author><author><name sortKey="Durif, Franck" sort="Durif, Franck" uniqKey="Durif F" first="Franck" last="Durif">Franck Durif</name><affiliation wicri:level="1"><inist:fA14 i1="03"><s1>Service de Neurologie A, Centre Hospitalier Universitaire</s1><s2>Clermont-Ferrand</s2><s3>FRA</s3><sZ>5 aut.</sZ></inist:fA14><country>France</country><placeName><settlement type="city">Clermont-Ferrand</settlement></placeName></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">INIST</idno><idno type="inist">05-0151002</idno><date when="2005">2005</date><idno type="stanalyst">PASCAL 05-0151002 INIST</idno><idno type="RBID">Pascal:05-0151002</idno><idno type="wicri:Area/PascalFrancis/Corpus">001F58</idno><idno type="wicri:Area/PascalFrancis/Curation">000D63</idno><idno type="wicri:Area/PascalFrancis/Checkpoint">001E24</idno><idno type="wicri:doubleKey">0885-3185:2005:Chapuis S:impact:of:the</idno><idno type="wicri:Area/Main/Merge">005302</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a">Impact of the motor complications of Parkinson's disease on the quality of life</title><author><name sortKey="Chapuis, Stephane" sort="Chapuis, Stephane" uniqKey="Chapuis S" first="Stéphane" last="Chapuis">Stéphane Chapuis</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Service de Neurologie, Centre Hospitalier</s1><s2>Vichy</s2><s3>FRA</s3><sZ>1 aut.</sZ></inist:fA14><country>France</country><placeName><settlement type="city">Vichy</settlement></placeName></affiliation></author><author><name sortKey="Ouchchane, Lemlih" sort="Ouchchane, Lemlih" uniqKey="Ouchchane L" first="Lemlih" last="Ouchchane">Lemlih Ouchchane</name><affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Service d'épidémiologie et d'économie de la santé</s1><s2>Clermont-Ferrand</s2><s3>FRA</s3><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ></inist:fA14><country>France</country><placeName><settlement type="city">Clermont-Ferrand</settlement></placeName></affiliation></author><author><name sortKey="Metz, Olivier" sort="Metz, Olivier" uniqKey="Metz O" first="Olivier" last="Metz">Olivier Metz</name><affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Service d'épidémiologie et d'économie de la santé</s1><s2>Clermont-Ferrand</s2><s3>FRA</s3><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ></inist:fA14><country>France</country><placeName><settlement type="city">Clermont-Ferrand</settlement></placeName></affiliation></author><author><name sortKey="Gerbaud, Laurent" sort="Gerbaud, Laurent" uniqKey="Gerbaud L" first="Laurent" last="Gerbaud">Laurent Gerbaud</name><affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Service d'épidémiologie et d'économie de la santé</s1><s2>Clermont-Ferrand</s2><s3>FRA</s3><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ></inist:fA14><country>France</country><placeName><settlement type="city">Clermont-Ferrand</settlement></placeName></affiliation></author><author><name sortKey="Durif, Franck" sort="Durif, Franck" uniqKey="Durif F" first="Franck" last="Durif">Franck Durif</name><affiliation wicri:level="1"><inist:fA14 i1="03"><s1>Service de Neurologie A, Centre Hospitalier Universitaire</s1><s2>Clermont-Ferrand</s2><s3>FRA</s3><sZ>5 aut.</sZ></inist:fA14><country>France</country><placeName><settlement type="city">Clermont-Ferrand</settlement></placeName></affiliation></author></analytic><series><title level="j" type="main">Movement disorders</title><title level="j" type="abbreviated">Mov. disord.</title><idno type="ISSN">0885-3185</idno><imprint><date when="2005">2005</date></imprint></series></biblStruct></sourceDesc><seriesStmt><title level="j" type="main">Movement disorders</title><title level="j" type="abbreviated">Mov. disord.</title><idno type="ISSN">0885-3185</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Complication</term><term>Nervous system diseases</term><term>Parkinson disease</term><term>Quality of life</term></keywords><keywords scheme="Pascal" xml:lang="fr"><term>Système nerveux pathologie</term><term>Complication</term><term>Qualité vie</term><term>Parkinson maladie</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">The impact of motor complications of Parkinson's disease (PD), especially levodopa-induced dyskinesias, on quality of life (QL) was studied in 143 patients with PD. All were evaluated on the Hoehn and Yahr (H&Y) scale, and the Motor part of the Unified Parkinson's Disease Rating Scale (UPDRS). Motor complications were analyzed using the UPDRS Parts IV<sub>A</sub> and IV<sub>B</sub> and the Abnormal Involuntary Movement Scale. A specific Parkinson's disease quality of life questionnaire (39-item version, PDQ-39) was used. Motor complications significantly worsened the PDQ-39 Summary Index (PDQ-SI) of patients with PD. The dimensions of Mobility, Activities of Daily Living, Stigma, and Communication were the most strongly affected. "Peak dose" dyskinesia decreased Mobility, Emotional Well-Being, and Cognition, whereas biphasic dyskinesia affected Mobility, Stigma, Communication, and Activities of Daily Living. Morning akinesia, end-of-dose fluctuations, and "unpredictable offs" decreased QL on the dimensions of Mobility, Activities of Daily Living, Stigma, and Communication. Nocturnal akinesia led to a deterioration of all dimensions of the PDQ-39. Thus, motor complications and especially nocturnal akinesia and biphasic dyskinesias worsened the QL of PD patients.</div></front></TEI><affiliations><list><country><li>France</li></country><settlement><li>Clermont-Ferrand</li><li>Vichy</li></settlement></list><tree><country name="France"><noRegion><name sortKey="Chapuis, Stephane" sort="Chapuis, Stephane" uniqKey="Chapuis S" first="Stéphane" last="Chapuis">Stéphane Chapuis</name></noRegion><name sortKey="Durif, Franck" sort="Durif, Franck" uniqKey="Durif F" first="Franck" last="Durif">Franck Durif</name><name sortKey="Gerbaud, Laurent" sort="Gerbaud, Laurent" uniqKey="Gerbaud L" first="Laurent" last="Gerbaud">Laurent Gerbaud</name><name sortKey="Metz, Olivier" sort="Metz, Olivier" uniqKey="Metz O" first="Olivier" last="Metz">Olivier Metz</name><name sortKey="Ouchchane, Lemlih" sort="Ouchchane, Lemlih" uniqKey="Ouchchane L" first="Lemlih" last="Ouchchane">Lemlih Ouchchane</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Santé/explor/MovDisordV3/Data/Main/Merge
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 005302 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Merge/biblio.hfd -nk 005302 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Santé
|area= MovDisordV3
|flux= Main
|étape= Merge
|type= RBID
|clé= Pascal:05-0151002
|texte= Impact of the motor complications of Parkinson's disease on the quality of life
}}
| This area was generated with Dilib version V0.6.23. |  |