Glutathione‐S‐transferase‐1 and interleukin‐1β gene polymorphisms in Japanese patients with Parkinson's disease
Identifieur interne : 004F91 ( Main/Merge ); précédent : 004F90; suivant : 004F92Glutathione‐S‐transferase‐1 and interleukin‐1β gene polymorphisms in Japanese patients with Parkinson's disease
Auteurs : Masataka Nishimura [Japon] ; Sadako Kuno [Japon] ; Ryuji Kaji [Japon] ; Katsuhito Yasuno [Japon] ; Hideshi Kawakami [Japon]Source :
- Movement Disorders [ 0885-3185 ] ; 2005-07.
Descripteurs français
- Wicri :
- geographic : Japon.
English descriptors
- KwdEn :
- Adult, Aged, Aged, 80 and over, Analysis of Variance, Chi-Square Distribution, Female, Genotype, Glutathione Transferase (genetics), Humans, Interleukin-1 (genetics), Japan (epidemiology), Japan (ethnology), Linkage Disequilibrium, Male, Middle Aged, Parkinson Disease (genetics), Parkinson's disease (PD), Polymorphism, Genetic, Polymorphism, Restriction Fragment Length, RNA, Messenger (biosynthesis), Reverse Transcriptase Polymerase Chain Reaction (methods), age at onset, glutathione‐S‐transferase‐1 (GST‐1), interleukin‐1β (IL‐1β), polymorphism.
- MESH :
- chemical , biosynthesis : RNA, Messenger.
- chemical , genetics : Glutathione Transferase, Interleukin-1.
- geographic , epidemiology : Japan.
- geographic , ethnology : Japan.
- genetics : Parkinson Disease.
- methods : Reverse Transcriptase Polymerase Chain Reaction.
- Adult, Aged, Aged, 80 and over, Analysis of Variance, Chi-Square Distribution, Female, Genotype, Humans, Linkage Disequilibrium, Male, Middle Aged, Polymorphism, Genetic, Polymorphism, Restriction Fragment Length.
Abstract
We studied genetic polymorphisms in the glutathione‐S‐transferase‐1 (GST‐1) gene region and the interleukin‐1β (IL‐1β) promoter region in patients with Parkinson's disease (PD, n = 361), as well as controls (n = 257). Although we have confirmed the previous results, in a larger sample, that the IL‐1β genotype has affected the age at onset of PD patients, no contribution of the GST‐1 gene polymorphism was observed in the allele frequency or the onset age of the disease in Japanese persons. © 2005 Movement Disorder Society
Url:
DOI: 10.1002/mds.20477
Links toward previous steps (curation, corpus...)
- to stream Istex, to step Corpus: 003833
- to stream Istex, to step Curation: 003833
- to stream Istex, to step Checkpoint: 002314
- to stream PubMed, to step Corpus: 003072
- to stream PubMed, to step Curation: 003072
- to stream PubMed, to step Checkpoint: 003117
- to stream Ncbi, to step Merge: 001229
- to stream Ncbi, to step Curation: 001229
- to stream Ncbi, to step Checkpoint: 001229
Links to Exploration step
ISTEX:4103B303C7D2D8EBB3BBBCFAA1FB16C95AC9AEC9Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Glutathione‐S‐transferase‐1 and interleukin‐1β gene polymorphisms in Japanese patients with Parkinson's disease</title><author><name sortKey="Nishimura, Masataka" sort="Nishimura, Masataka" uniqKey="Nishimura M" first="Masataka" last="Nishimura">Masataka Nishimura</name></author><author><name sortKey="Kuno, Sadako" sort="Kuno, Sadako" uniqKey="Kuno S" first="Sadako" last="Kuno">Sadako Kuno</name></author><author><name sortKey="Kaji, Ryuji" sort="Kaji, Ryuji" uniqKey="Kaji R" first="Ryuji" last="Kaji">Ryuji Kaji</name></author><author><name sortKey="Yasuno, Katsuhito" sort="Yasuno, Katsuhito" uniqKey="Yasuno K" first="Katsuhito" last="Yasuno">Katsuhito Yasuno</name></author><author><name sortKey="Kawakami, Hideshi" sort="Kawakami, Hideshi" uniqKey="Kawakami H" first="Hideshi" last="Kawakami">Hideshi Kawakami</name></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:4103B303C7D2D8EBB3BBBCFAA1FB16C95AC9AEC9</idno><date when="2005" year="2005">2005</date><idno type="doi">10.1002/mds.20477</idno><idno type="url">https://api.istex.fr/document/4103B303C7D2D8EBB3BBBCFAA1FB16C95AC9AEC9/fulltext/pdf</idno><idno type="wicri:Area/Istex/Corpus">003833</idno><idno type="wicri:Area/Istex/Curation">003833</idno><idno type="wicri:Area/Istex/Checkpoint">002314</idno><idno type="wicri:doubleKey">0885-3185:2005:Nishimura M:glutathione:s:transferase</idno><idno type="wicri:source">PubMed</idno><idno type="RBID">pubmed:15834859</idno><idno type="wicri:Area/PubMed/Corpus">003072</idno><idno type="wicri:Area/PubMed/Curation">003072</idno><idno type="wicri:Area/PubMed/Checkpoint">003117</idno><idno type="wicri:Area/Ncbi/Merge">001229</idno><idno type="wicri:Area/Ncbi/Curation">001229</idno><idno type="wicri:Area/Ncbi/Checkpoint">001229</idno><idno type="wicri:doubleKey">0885-3185:2005:Nishimura M:glutathione:s:transferase</idno><idno type="wicri:Area/Main/Merge">004F91</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Glutathione‐S‐transferase‐1 and interleukin‐1β gene polymorphisms in Japanese patients with Parkinson's disease</title><author><name sortKey="Nishimura, Masataka" sort="Nishimura, Masataka" uniqKey="Nishimura M" first="Masataka" last="Nishimura">Masataka Nishimura</name><affiliation wicri:level="1"><country xml:lang="fr">Japon</country><wicri:regionArea>Clinical Research Center, Konan Hospital, Shiga</wicri:regionArea><wicri:noRegion>Shiga</wicri:noRegion></affiliation></author><author><name sortKey="Kuno, Sadako" sort="Kuno, Sadako" uniqKey="Kuno S" first="Sadako" last="Kuno">Sadako Kuno</name><affiliation wicri:level="3"><country xml:lang="fr">Japon</country><wicri:regionArea>Musashi Hospital, National Center of Neurology and Psychiatry, Kodaira, Tokyo</wicri:regionArea><placeName><settlement type="city">Tokyo</settlement></placeName></affiliation></author><author><name sortKey="Kaji, Ryuji" sort="Kaji, Ryuji" uniqKey="Kaji R" first="Ryuji" last="Kaji">Ryuji Kaji</name><affiliation wicri:level="1"><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Neurology, Tokushima University School of Medicine, Tokushima</wicri:regionArea><wicri:noRegion>Tokushima</wicri:noRegion></affiliation></author><author><name sortKey="Yasuno, Katsuhito" sort="Yasuno, Katsuhito" uniqKey="Yasuno K" first="Katsuhito" last="Yasuno">Katsuhito Yasuno</name><affiliation wicri:level="3"><country xml:lang="fr">Japon</country><wicri:regionArea>Genome Diversity Team, Japan Biological Information Research Center, Japan Biological Informatics Consortium, AIST Tokyo Waterfront, Tokyo</wicri:regionArea><placeName><settlement type="city">Tokyo</settlement></placeName></affiliation></author><author><name sortKey="Kawakami, Hideshi" sort="Kawakami, Hideshi" uniqKey="Kawakami H" first="Hideshi" last="Kawakami">Hideshi Kawakami</name><affiliation wicri:level="1"><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Clinical Neuroscience and Therapeutics, Hiroshima University Graduate School of Biomedical Science, Hiroshima</wicri:regionArea><wicri:noRegion>Hiroshima</wicri:noRegion></affiliation></author></analytic><monogr></monogr><series><title level="j">Movement Disorders</title><title level="j" type="sub">Official Journal of the Movement Disorder Society</title><title level="j" type="abbrev">Mov. Disord.</title><idno type="ISSN">0885-3185</idno><idno type="eISSN">1531-8257</idno><imprint><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><pubPlace>Hoboken</pubPlace><date type="published" when="2005-07">2005-07</date><biblScope unit="vol">20</biblScope><biblScope unit="issue">7</biblScope><biblScope unit="page" from="901">901</biblScope><biblScope unit="page" to="902">902</biblScope></imprint><idno type="ISSN">0885-3185</idno></series><idno type="istex">4103B303C7D2D8EBB3BBBCFAA1FB16C95AC9AEC9</idno><idno type="DOI">10.1002/mds.20477</idno><idno type="ArticleID">MDS20477</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0885-3185</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term><term>Aged</term><term>Aged, 80 and over</term><term>Analysis of Variance</term><term>Chi-Square Distribution</term><term>Female</term><term>Genotype</term><term>Glutathione Transferase (genetics)</term><term>Humans</term><term>Interleukin-1 (genetics)</term><term>Japan (epidemiology)</term><term>Japan (ethnology)</term><term>Linkage Disequilibrium</term><term>Male</term><term>Middle Aged</term><term>Parkinson Disease (genetics)</term><term>Parkinson's disease (PD)</term><term>Polymorphism, Genetic</term><term>Polymorphism, Restriction Fragment Length</term><term>RNA, Messenger (biosynthesis)</term><term>Reverse Transcriptase Polymerase Chain Reaction (methods)</term><term>age at onset</term><term>glutathione‐S‐transferase‐1 (GST‐1)</term><term>interleukin‐1β (IL‐1β)</term><term>polymorphism</term></keywords><keywords scheme="MESH" type="chemical" qualifier="biosynthesis" xml:lang="en"><term>RNA, Messenger</term></keywords><keywords scheme="MESH" type="chemical" qualifier="genetics" xml:lang="en"><term>Glutathione Transferase</term><term>Interleukin-1</term></keywords><keywords scheme="MESH" type="geographic" qualifier="epidemiology" xml:lang="en"><term>Japan</term></keywords><keywords scheme="MESH" type="geographic" qualifier="ethnology" xml:lang="en"><term>Japan</term></keywords><keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Parkinson Disease</term></keywords><keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Reverse Transcriptase Polymerase Chain Reaction</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adult</term><term>Aged</term><term>Aged, 80 and over</term><term>Analysis of Variance</term><term>Chi-Square Distribution</term><term>Female</term><term>Genotype</term><term>Humans</term><term>Linkage Disequilibrium</term><term>Male</term><term>Middle Aged</term><term>Polymorphism, Genetic</term><term>Polymorphism, Restriction Fragment Length</term></keywords><keywords scheme="Wicri" type="geographic" xml:lang="fr"><term>Japon</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">We studied genetic polymorphisms in the glutathione‐S‐transferase‐1 (GST‐1) gene region and the interleukin‐1β (IL‐1β) promoter region in patients with Parkinson's disease (PD, n = 361), as well as controls (n = 257). Although we have confirmed the previous results, in a larger sample, that the IL‐1β genotype has affected the age at onset of PD patients, no contribution of the GST‐1 gene polymorphism was observed in the allele frequency or the onset age of the disease in Japanese persons. © 2005 Movement Disorder Society</div></front></TEI><double doi="10.1002/mds.20477"><ISTEX><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Glutathione‐S‐transferase‐1 and interleukin‐1β gene polymorphisms in Japanese patients with Parkinson's disease</title><author><name sortKey="Nishimura, Masataka" sort="Nishimura, Masataka" uniqKey="Nishimura M" first="Masataka" last="Nishimura">Masataka Nishimura</name></author><author><name sortKey="Kuno, Sadako" sort="Kuno, Sadako" uniqKey="Kuno S" first="Sadako" last="Kuno">Sadako Kuno</name></author><author><name sortKey="Kaji, Ryuji" sort="Kaji, Ryuji" uniqKey="Kaji R" first="Ryuji" last="Kaji">Ryuji Kaji</name></author><author><name sortKey="Yasuno, Katsuhito" sort="Yasuno, Katsuhito" uniqKey="Yasuno K" first="Katsuhito" last="Yasuno">Katsuhito Yasuno</name></author><author><name sortKey="Kawakami, Hideshi" sort="Kawakami, Hideshi" uniqKey="Kawakami H" first="Hideshi" last="Kawakami">Hideshi Kawakami</name></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:4103B303C7D2D8EBB3BBBCFAA1FB16C95AC9AEC9</idno><date when="2005" year="2005">2005</date><idno type="doi">10.1002/mds.20477</idno><idno type="url">https://api.istex.fr/document/4103B303C7D2D8EBB3BBBCFAA1FB16C95AC9AEC9/fulltext/pdf</idno><idno type="wicri:Area/Istex/Corpus">003833</idno><idno type="wicri:Area/Istex/Curation">003833</idno><idno type="wicri:Area/Istex/Checkpoint">002314</idno><idno type="wicri:doubleKey">0885-3185:2005:Nishimura M:glutathione:s:transferase</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Glutathione‐S‐transferase‐1 and interleukin‐1β gene polymorphisms in Japanese patients with Parkinson's disease</title><author><name sortKey="Nishimura, Masataka" sort="Nishimura, Masataka" uniqKey="Nishimura M" first="Masataka" last="Nishimura">Masataka Nishimura</name><affiliation wicri:level="1"><country xml:lang="fr">Japon</country><wicri:regionArea>Clinical Research Center, Konan Hospital, Shiga</wicri:regionArea><wicri:noRegion>Shiga</wicri:noRegion></affiliation></author><author><name sortKey="Kuno, Sadako" sort="Kuno, Sadako" uniqKey="Kuno S" first="Sadako" last="Kuno">Sadako Kuno</name><affiliation wicri:level="3"><country xml:lang="fr">Japon</country><wicri:regionArea>Musashi Hospital, National Center of Neurology and Psychiatry, Kodaira, Tokyo</wicri:regionArea><placeName><settlement type="city">Tokyo</settlement></placeName></affiliation></author><author><name sortKey="Kaji, Ryuji" sort="Kaji, Ryuji" uniqKey="Kaji R" first="Ryuji" last="Kaji">Ryuji Kaji</name><affiliation wicri:level="1"><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Neurology, Tokushima University School of Medicine, Tokushima</wicri:regionArea><wicri:noRegion>Tokushima</wicri:noRegion></affiliation></author><author><name sortKey="Yasuno, Katsuhito" sort="Yasuno, Katsuhito" uniqKey="Yasuno K" first="Katsuhito" last="Yasuno">Katsuhito Yasuno</name><affiliation wicri:level="3"><country xml:lang="fr">Japon</country><wicri:regionArea>Genome Diversity Team, Japan Biological Information Research Center, Japan Biological Informatics Consortium, AIST Tokyo Waterfront, Tokyo</wicri:regionArea><placeName><settlement type="city">Tokyo</settlement></placeName></affiliation></author><author><name sortKey="Kawakami, Hideshi" sort="Kawakami, Hideshi" uniqKey="Kawakami H" first="Hideshi" last="Kawakami">Hideshi Kawakami</name><affiliation wicri:level="1"><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Clinical Neuroscience and Therapeutics, Hiroshima University Graduate School of Biomedical Science, Hiroshima</wicri:regionArea><wicri:noRegion>Hiroshima</wicri:noRegion></affiliation></author></analytic><monogr></monogr><series><title level="j">Movement Disorders</title><title level="j" type="sub">Official Journal of the Movement Disorder Society</title><title level="j" type="abbrev">Mov. Disord.</title><idno type="ISSN">0885-3185</idno><idno type="eISSN">1531-8257</idno><imprint><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><pubPlace>Hoboken</pubPlace><date type="published" when="2005-07">2005-07</date><biblScope unit="vol">20</biblScope><biblScope unit="issue">7</biblScope><biblScope unit="page" from="901">901</biblScope><biblScope unit="page" to="902">902</biblScope></imprint><idno type="ISSN">0885-3185</idno></series><idno type="istex">4103B303C7D2D8EBB3BBBCFAA1FB16C95AC9AEC9</idno><idno type="DOI">10.1002/mds.20477</idno><idno type="ArticleID">MDS20477</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0885-3185</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Parkinson's disease (PD)</term><term>age at onset</term><term>glutathione‐S‐transferase‐1 (GST‐1)</term><term>interleukin‐1β (IL‐1β)</term><term>polymorphism</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">We studied genetic polymorphisms in the glutathione‐S‐transferase‐1 (GST‐1) gene region and the interleukin‐1β (IL‐1β) promoter region in patients with Parkinson's disease (PD, n = 361), as well as controls (n = 257). Although we have confirmed the previous results, in a larger sample, that the IL‐1β genotype has affected the age at onset of PD patients, no contribution of the GST‐1 gene polymorphism was observed in the allele frequency or the onset age of the disease in Japanese persons. © 2005 Movement Disorder Society</div></front></TEI></ISTEX><PubMed><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Glutathione-S-transferase-1 and interleukin-1beta gene polymorphisms in Japanese patients with Parkinson's disease.</title><author><name sortKey="Nishimura, Masataka" sort="Nishimura, Masataka" uniqKey="Nishimura M" first="Masataka" last="Nishimura">Masataka Nishimura</name><affiliation wicri:level="1"><nlm:affiliation>Clinical Research Center, Konan Hospital, Shiga, Japan. ma-nishi@vmail.plala.or.jp</nlm:affiliation><country xml:lang="fr">Japon</country><wicri:regionArea>Clinical Research Center, Konan Hospital, Shiga</wicri:regionArea><wicri:noRegion>Shiga</wicri:noRegion></affiliation></author><author><name sortKey="Kuno, Sadako" sort="Kuno, Sadako" uniqKey="Kuno S" first="Sadako" last="Kuno">Sadako Kuno</name></author><author><name sortKey="Kaji, Ryuji" sort="Kaji, Ryuji" uniqKey="Kaji R" first="Ryuji" last="Kaji">Ryuji Kaji</name></author><author><name sortKey="Yasuno, Katsuhito" sort="Yasuno, Katsuhito" uniqKey="Yasuno K" first="Katsuhito" last="Yasuno">Katsuhito Yasuno</name></author><author><name sortKey="Kawakami, Hideshi" sort="Kawakami, Hideshi" uniqKey="Kawakami H" first="Hideshi" last="Kawakami">Hideshi Kawakami</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2005">2005</date><idno type="doi">10.1002/mds.20477</idno><idno type="RBID">pubmed:15834859</idno><idno type="pmid">15834859</idno><idno type="wicri:Area/PubMed/Corpus">003072</idno><idno type="wicri:Area/PubMed/Curation">003072</idno><idno type="wicri:Area/PubMed/Checkpoint">003117</idno><idno type="wicri:Area/Ncbi/Merge">001229</idno><idno type="wicri:Area/Ncbi/Curation">001229</idno><idno type="wicri:Area/Ncbi/Checkpoint">001229</idno><idno type="wicri:doubleKey">0885-3185:2005:Nishimura M:glutathione:s:transferase</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Glutathione-S-transferase-1 and interleukin-1beta gene polymorphisms in Japanese patients with Parkinson's disease.</title><author><name sortKey="Nishimura, Masataka" sort="Nishimura, Masataka" uniqKey="Nishimura M" first="Masataka" last="Nishimura">Masataka Nishimura</name><affiliation wicri:level="1"><nlm:affiliation>Clinical Research Center, Konan Hospital, Shiga, Japan. ma-nishi@vmail.plala.or.jp</nlm:affiliation><country xml:lang="fr">Japon</country><wicri:regionArea>Clinical Research Center, Konan Hospital, Shiga</wicri:regionArea><wicri:noRegion>Shiga</wicri:noRegion></affiliation></author><author><name sortKey="Kuno, Sadako" sort="Kuno, Sadako" uniqKey="Kuno S" first="Sadako" last="Kuno">Sadako Kuno</name></author><author><name sortKey="Kaji, Ryuji" sort="Kaji, Ryuji" uniqKey="Kaji R" first="Ryuji" last="Kaji">Ryuji Kaji</name></author><author><name sortKey="Yasuno, Katsuhito" sort="Yasuno, Katsuhito" uniqKey="Yasuno K" first="Katsuhito" last="Yasuno">Katsuhito Yasuno</name></author><author><name sortKey="Kawakami, Hideshi" sort="Kawakami, Hideshi" uniqKey="Kawakami H" first="Hideshi" last="Kawakami">Hideshi Kawakami</name></author></analytic><series><title level="j">Movement disorders : official journal of the Movement Disorder Society</title><idno type="ISSN">0885-3185</idno><imprint><date when="2005" type="published">2005</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term><term>Aged</term><term>Aged, 80 and over</term><term>Analysis of Variance</term><term>Chi-Square Distribution</term><term>Female</term><term>Genotype</term><term>Glutathione Transferase (genetics)</term><term>Humans</term><term>Interleukin-1 (genetics)</term><term>Japan (epidemiology)</term><term>Japan (ethnology)</term><term>Linkage Disequilibrium</term><term>Male</term><term>Middle Aged</term><term>Parkinson Disease (genetics)</term><term>Polymorphism, Genetic</term><term>Polymorphism, Restriction Fragment Length</term><term>RNA, Messenger (biosynthesis)</term><term>Reverse Transcriptase Polymerase Chain Reaction (methods)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="biosynthesis" xml:lang="en"><term>RNA, Messenger</term></keywords><keywords scheme="MESH" type="chemical" qualifier="genetics" xml:lang="en"><term>Glutathione Transferase</term><term>Interleukin-1</term></keywords><keywords scheme="MESH" type="geographic" qualifier="epidemiology" xml:lang="en"><term>Japan</term></keywords><keywords scheme="MESH" type="geographic" qualifier="ethnology" xml:lang="en"><term>Japan</term></keywords><keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Parkinson Disease</term></keywords><keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Reverse Transcriptase Polymerase Chain Reaction</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adult</term><term>Aged</term><term>Aged, 80 and over</term><term>Analysis of Variance</term><term>Chi-Square Distribution</term><term>Female</term><term>Genotype</term><term>Humans</term><term>Linkage Disequilibrium</term><term>Male</term><term>Middle Aged</term><term>Polymorphism, Genetic</term><term>Polymorphism, Restriction Fragment Length</term></keywords><keywords scheme="Wicri" type="geographic" xml:lang="fr"><term>Japon</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">We studied genetic polymorphisms in the glutathione-S-transferase-1 (GST-1) gene region and the interleukin-1beta (IL-1beta) promoter region in patients with Parkinson's disease (PD, n = 361), as well as controls (n = 257). Although we have confirmed the previous results, in a larger sample, that the IL-1beta genotype has affected the age at onset of PD patients, no contribution of the GST-1 gene polymorphism was observed in the allele frequency or the onset age of the disease in Japanese persons.</div></front></TEI></PubMed></double></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Santé/explor/MovDisordV3/Data/Main/Merge
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 004F91 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Merge/biblio.hfd -nk 004F91 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Santé
|area= MovDisordV3
|flux= Main
|étape= Merge
|type= RBID
|clé= ISTEX:4103B303C7D2D8EBB3BBBCFAA1FB16C95AC9AEC9
|texte= Glutathione‐S‐transferase‐1 and interleukin‐1β gene polymorphisms in Japanese patients with Parkinson's disease
}}
| This area was generated with Dilib version V0.6.23. |  |