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Botulinum toxin A may be efficacious as treatment for jaw tremor in Parkinson's disease

Identifieur interne : 004D04 ( Main/Merge ); précédent : 004D03; suivant : 004D05

Botulinum toxin A may be efficacious as treatment for jaw tremor in Parkinson's disease

Auteurs : Susanne A. Schneider [Royaume-Uni] ; Mark J. Edwards [Royaume-Uni] ; Carla Cordivari [Royaume-Uni] ; William N. Macleod [Royaume-Uni] ; Kailash P. Bhatia [Royaume-Uni]

Source :

Movement disorders [ 0885-3185 ] ; 2006.

RBID : Pascal:06-0538593

Descripteurs français

Pascal (Inist)
- Système nerveux pathologie, Tremblement, Parkinson maladie, Bontoxilysin, Traitement, Mâchoire, Muscle masseter.

English descriptors

KwdEn :
- Bontoxilysin, Jaw, Masseter muscle, Nervous system diseases, Parkinson disease, Treatment, Tremor.

Abstract

Jaw tremor in Parkinson's disease (PD) may not respond well to conventional treatment. It causes embarrassment and social handicap. We piloted the use of botulinum toxin (BTX) injections in three patients with PD jaw tremor. BTX A (Dysport; mean, 53 U; range, 30-100 U) was given into each masseter muscle. Outcome was assessed by subjective and clinical improvement and by video recording before and 4 to 9 weeks after injections. There was an excellent response in all without side effects. BTX injections into the masseter may effectively improve jaw tremor and be useful in PD and other conditions.

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Pascal:06-0538593

Le document en format XML

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<author><name sortKey="Schneider, Susanne A" sort="Schneider, Susanne A" uniqKey="Schneider S" first="Susanne A." last="Schneider">Susanne A. Schneider</name>
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<author><name sortKey="Bhatia, Kailash P" sort="Bhatia, Kailash P" uniqKey="Bhatia K" first="Kailash P." last="Bhatia">Kailash P. Bhatia</name>
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<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a">Botulinum toxin A may be efficacious as treatment for jaw tremor in Parkinson's disease</title>
<author><name sortKey="Schneider, Susanne A" sort="Schneider, Susanne A" uniqKey="Schneider S" first="Susanne A." last="Schneider">Susanne A. Schneider</name>
<affiliation wicri:level="3"><inist:fA14 i1="01"><s1>Sobell Department of Motorneuron Disease and Movement Disorders, Institute of Neurology</s1>
<s2>London</s2>
<s3>GBR</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>5 aut.</sZ>
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<country>Royaume-Uni</country>
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<author><name sortKey="Edwards, Mark J" sort="Edwards, Mark J" uniqKey="Edwards M" first="Mark J." last="Edwards">Mark J. Edwards</name>
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</affiliation>
</author>
<author><name sortKey="Cordivari, Carla" sort="Cordivari, Carla" uniqKey="Cordivari C" first="Carla" last="Cordivari">Carla Cordivari</name>
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<s2>London</s2>
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<region type="région" nuts="1">Grand Londres</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Macleod, William N" sort="Macleod, William N" uniqKey="Macleod W" first="William N." last="Macleod">William N. Macleod</name>
<affiliation wicri:level="1"><inist:fA14 i1="03"><s1>District General Hospital</s1>
<s2>Eastbourne</s2>
<s3>GBR</s3>
<sZ>4 aut.</sZ>
</inist:fA14>
<country>Royaume-Uni</country>
<wicri:noRegion>District General Hospital</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Bhatia, Kailash P" sort="Bhatia, Kailash P" uniqKey="Bhatia K" first="Kailash P." last="Bhatia">Kailash P. Bhatia</name>
<affiliation wicri:level="3"><inist:fA14 i1="01"><s1>Sobell Department of Motorneuron Disease and Movement Disorders, Institute of Neurology</s1>
<s2>London</s2>
<s3>GBR</s3>
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<sZ>2 aut.</sZ>
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<region type="country">Angleterre</region>
<region type="région" nuts="1">Grand Londres</region>
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<series><title level="j" type="main">Movement disorders</title>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Bontoxilysin</term>
<term>Jaw</term>
<term>Masseter muscle</term>
<term>Nervous system diseases</term>
<term>Parkinson disease</term>
<term>Treatment</term>
<term>Tremor</term>
</keywords>
<keywords scheme="Pascal" xml:lang="fr"><term>Système nerveux pathologie</term>
<term>Tremblement</term>
<term>Parkinson maladie</term>
<term>Bontoxilysin</term>
<term>Traitement</term>
<term>Mâchoire</term>
<term>Muscle masseter</term>
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<front><div type="abstract" xml:lang="en">Jaw tremor in Parkinson's disease (PD) may not respond well to conventional treatment. It causes embarrassment and social handicap. We piloted the use of botulinum toxin (BTX) injections in three patients with PD jaw tremor. BTX A (Dysport; mean, 53 U; range, 30-100 U) was given into each masseter muscle. Outcome was assessed by subjective and clinical improvement and by video recording before and 4 to 9 weeks after injections. There was an excellent response in all without side effects. BTX injections into the masseter may effectively improve jaw tremor and be useful in PD and other conditions.</div>
</front>
</TEI>
<affiliations><list><country><li>Royaume-Uni</li>
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<region><li>Angleterre</li>
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<settlement><li>Londres</li>
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<tree><country name="Royaume-Uni"><region name="Angleterre"><name sortKey="Schneider, Susanne A" sort="Schneider, Susanne A" uniqKey="Schneider S" first="Susanne A." last="Schneider">Susanne A. Schneider</name>
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<name sortKey="Bhatia, Kailash P" sort="Bhatia, Kailash P" uniqKey="Bhatia K" first="Kailash P." last="Bhatia">Kailash P. Bhatia</name>
<name sortKey="Cordivari, Carla" sort="Cordivari, Carla" uniqKey="Cordivari C" first="Carla" last="Cordivari">Carla Cordivari</name>
<name sortKey="Edwards, Mark J" sort="Edwards, Mark J" uniqKey="Edwards M" first="Mark J." last="Edwards">Mark J. Edwards</name>
<name sortKey="Macleod, William N" sort="Macleod, William N" uniqKey="Macleod W" first="William N." last="Macleod">William N. Macleod</name>
</country>
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</record>

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	Movement Disorders (revue)
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Movement Disorders (revue)

Botulinum toxin A may be efficacious as treatment for jaw tremor in Parkinson's disease

Botulinum toxin A may be efficacious as treatment for jaw tremor in Parkinson's disease

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri