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Botulinum toxin and neuromotor rehabilitation : An integrated approach to idiopathic cervical dystonia

Identifieur interne : 004D03 ( Main/Merge ); précédent : 004D02; suivant : 004D04

Botulinum toxin and neuromotor rehabilitation : An integrated approach to idiopathic cervical dystonia

Auteurs : Cristina Tassorelli [Italie] ; Francesca Mancini [Italie] ; Laura Balloni [Italie] ; Claudio Pacchetti [Italie] ; Giorgio Sandrini [Italie] ; Giuseppe Nappi [Italie] ; Emilia Martignoni [Italie]

Source :

Movement disorders [ 0885-3185 ] ; 2006.

RBID : Pascal:07-0090890

Descripteurs français

Pascal (Inist)
- Système nerveux pathologie, Dystonie, Bontoxilysin, Réhabilitation, Voie abord, Idiopathique, Physiothérapie, Biofeedback.

English descriptors

KwdEn :
- Biofeedback, Bontoxilysin, Dystonia, Idiopathic, Nervous system diseases, Physiotherapy, Rehabilitation, Surgical approach.

Abstract

Currently, the best treatment option for idiopathic cervical dystonia (ICD) is injection of botulinum toxin (BTX) into the affected muscles, whereas rehabilitative approaches have given disappointing results. We evaluated whether the association of an ad hoc rehabilitative program may improve the clinical efficacy of BTX treatment in a single-center, cross-over, controlled study. Forty patients with ICD were randomly assigned to two different treatment groups: (1) BTX type A (BTX-A) plus a specific program of physical therapy (BTX-PT) or (2) BTX-A alone (BTX-0). Patients in the BTX-PT group showed a longer duration of the clinical benefit (118.8 vs. 99.1 days) and needed a lower dose of BTX at reinjection (284.5 vs. 325.5 units). In addition, they showed more marked reductions in their disability in activities of daily living (-9.7 vs. -4.85 points) and subjective pain (-13.35 vs. 6.95 points) scores. Association of BTX-A therapy with a specific program of physical therapy may improve ICD treatment outcome.

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Le document en format XML

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<front><div type="abstract" xml:lang="en">Currently, the best treatment option for idiopathic cervical dystonia (ICD) is injection of botulinum toxin (BTX) into the affected muscles, whereas rehabilitative approaches have given disappointing results. We evaluated whether the association of an ad hoc rehabilitative program may improve the clinical efficacy of BTX treatment in a single-center, cross-over, controlled study. Forty patients with ICD were randomly assigned to two different treatment groups: (1) BTX type A (BTX-A) plus a specific program of physical therapy (BTX-PT) or (2) BTX-A alone (BTX-0). Patients in the BTX-PT group showed a longer duration of the clinical benefit (118.8 vs. 99.1 days) and needed a lower dose of BTX at reinjection (284.5 vs. 325.5 units). In addition, they showed more marked reductions in their disability in activities of daily living (-9.7 vs. -4.85 points) and subjective pain (-13.35 vs. 6.95 points) scores. Association of BTX-A therapy with a specific program of physical therapy may improve ICD treatment outcome.</div>
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	Movement Disorders (revue)
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Movement Disorders (revue)

Botulinum toxin and neuromotor rehabilitation : An integrated approach to idiopathic cervical dystonia

Botulinum toxin and neuromotor rehabilitation : An integrated approach to idiopathic cervical dystonia

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri