MovDisordV3, Main, Merge, bibRecord, 004A07

Reversible parkinsonism and T1W pallidal hyperintensities in acute liver failure

Identifieur interne : 004A07 ( Main/Merge ); précédent : 004A06; suivant : 004A08

Reversible parkinsonism and T1W pallidal hyperintensities in acute liver failure

Auteurs : Annu Aggarwal [Inde] ; Sachin Vaidya [Inde] ; Samir Shah [Inde] ; Joshita Singh [Inde] ; Shrinivas Desai [Inde] ; Mohit Bhatt [Inde]

Source :

Movement disorders [ 0885-3185 ] ; 2006.

RBID : Pascal:07-0021732

Descripteurs français

Pascal (Inist)
- Système nerveux pathologie, Parkinsonisme, Insuffisance hépatique, Hyperintensité, Manganèse.
Wicri :
- topic : Manganèse.

English descriptors

KwdEn :
- Hyperintensity, Liver failure, Manganese, Nervous system diseases, Parkinsonism.

Abstract

We report on a young woman who survived acute liver failure (ALF) without liver transplant. During the ALF, she developed a disabling, levodopa-unresponsive, symmetrical Parkinsonism. This was characterized by severe bradykinesia, mild rigidity, mutism, and prominent gait impairment. Magnetic resonance imaging (MRI) showed bilateral T1W pallidal hyperintensities. Parkinsonism and MRI changes remitted in parallel with normalization of hepatic function. We implicate excessive pallidal manganese deposition secondary to ALF in the pathogenesis of this neuroradiological syndrome. Though hitherto unreported, we propose that Parkinsonism with T1W pallidal hyperintensities may not be uncommon in ALF.

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Pascal:07-0021732

Le document en format XML

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<author><name sortKey="Aggarwal, Annu" sort="Aggarwal, Annu" uniqKey="Aggarwal A" first="Annu" last="Aggarwal">Annu Aggarwal</name>
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<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a">Reversible parkinsonism and T1W pallidal hyperintensities in acute liver failure</title>
<author><name sortKey="Aggarwal, Annu" sort="Aggarwal, Annu" uniqKey="Aggarwal A" first="Annu" last="Aggarwal">Annu Aggarwal</name>
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<s2>Mumbai</s2>
<s3>IND</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
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<author><name sortKey="Vaidya, Sachin" sort="Vaidya, Sachin" uniqKey="Vaidya S" first="Sachin" last="Vaidya">Sachin Vaidya</name>
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<author><name sortKey="Bhatt, Mohit" sort="Bhatt, Mohit" uniqKey="Bhatt M" first="Mohit" last="Bhatt">Mohit Bhatt</name>
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<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
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<series><title level="j" type="main">Movement disorders</title>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Hyperintensity</term>
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<keywords scheme="Pascal" xml:lang="fr"><term>Système nerveux pathologie</term>
<term>Parkinsonisme</term>
<term>Insuffisance hépatique</term>
<term>Hyperintensité</term>
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<front><div type="abstract" xml:lang="en">We report on a young woman who survived acute liver failure (ALF) without liver transplant. During the ALF, she developed a disabling, levodopa-unresponsive, symmetrical Parkinsonism. This was characterized by severe bradykinesia, mild rigidity, mutism, and prominent gait impairment. Magnetic resonance imaging (MRI) showed bilateral T1W pallidal hyperintensities. Parkinsonism and MRI changes remitted in parallel with normalization of hepatic function. We implicate excessive pallidal manganese deposition secondary to ALF in the pathogenesis of this neuroradiological syndrome. Though hitherto unreported, we propose that Parkinsonism with T1W pallidal hyperintensities may not be uncommon in ALF.</div>
</front>
</TEI>
<affiliations><list><country><li>Inde</li>
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<tree><country name="Inde"><noRegion><name sortKey="Aggarwal, Annu" sort="Aggarwal, Annu" uniqKey="Aggarwal A" first="Annu" last="Aggarwal">Annu Aggarwal</name>
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<name sortKey="Bhatt, Mohit" sort="Bhatt, Mohit" uniqKey="Bhatt M" first="Mohit" last="Bhatt">Mohit Bhatt</name>
<name sortKey="Desai, Shrinivas" sort="Desai, Shrinivas" uniqKey="Desai S" first="Shrinivas" last="Desai">Shrinivas Desai</name>
<name sortKey="Shah, Samir" sort="Shah, Samir" uniqKey="Shah S" first="Samir" last="Shah">Samir Shah</name>
<name sortKey="Singh, Joshita" sort="Singh, Joshita" uniqKey="Singh J" first="Joshita" last="Singh">Joshita Singh</name>
<name sortKey="Vaidya, Sachin" sort="Vaidya, Sachin" uniqKey="Vaidya S" first="Sachin" last="Vaidya">Sachin Vaidya</name>
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</record>

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	Movement Disorders (revue)
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Movement Disorders (revue)

Reversible parkinsonism and T1W pallidal hyperintensities in acute liver failure

Reversible parkinsonism and T1W pallidal hyperintensities in acute liver failure

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri