Antero‐ventral internal pallidum stimulation improves behavioral disorders in Lesch–Nyhan disease
Identifieur interne : 003F42 ( Main/Merge ); précédent : 003F41; suivant : 003F43Antero‐ventral internal pallidum stimulation improves behavioral disorders in Lesch–Nyhan disease
Auteurs : Laura Cif [France] ; Brigitte Biolsi [France] ; Sophie Gavarini [France] ; Aude Saux [France] ; Santiago Gil Robles [France] ; Cornel Tancu [France] ; Xavier Vasques [France] ; Philippe Coubes [France]Source :
- Movement Disorders [ 0885-3185 ] ; 2007-10-31.
English descriptors
- KwdEn :
- Adolescent, Behavioral Symptoms (etiology), Behavioral Symptoms (therapy), DBS, Electric Stimulation Therapy (methods), Globus Pallidus (physiopathology), Globus Pallidus (radiation effects), Humans, Lesch-Nyhan Syndrome (complications), Lesch–Nyhan disease, Male, dystonia, internal pallidum, self injury.
- MESH :
- complications : Lesch-Nyhan Syndrome.
- etiology : Behavioral Symptoms.
- methods : Electric Stimulation Therapy.
- physiopathology : Globus Pallidus.
- radiation effects : Globus Pallidus.
- therapy : Behavioral Symptoms.
- Adolescent, Humans, Male.
Abstract
The Lesch–Nyhan syndrome is an X‐linked recessive disorder caused by a deficiency in hypoxanthine–guanine phosphoribosyl transferase, a purine salvage enzyme. Affected individuals exhibit a characteristic neurobehavioral disorder with delayed acquisition of motor skills, dystonia, severe self‐mutilations, and aggressive behavior. Deep brain stimulation has been previously proposed for controlling isolated involuntary movements and psychiatric disorders. We applied a double bilateral simultaneous stimulation to limbic and motor internal pallidum in one patient for controlling both behavioral and movement disorders, respectively. The injurious compulsions disappeared; dystonia and dyskinesia were decreased at 28 months follow‐up. © 2007 Movement Disorder Society
Url:
DOI: 10.1002/mds.21723
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Affected individuals exhibit a characteristic neurobehavioral disorder with delayed acquisition of motor skills, dystonia, severe self‐mutilations, and aggressive behavior. Deep brain stimulation has been previously proposed for controlling isolated involuntary movements and psychiatric disorders. We applied a double bilateral simultaneous stimulation to limbic and motor internal pallidum in one patient for controlling both behavioral and movement disorders, respectively. The injurious compulsions disappeared; dystonia and dyskinesia were decreased at 28 months follow‐up. © 2007 Movement Disorder Society</div></front></TEI><double doi="10.1002/mds.21723"><ISTEX><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Antero‐ventral internal pallidum stimulation improves behavioral disorders in Lesch–Nyhan disease</title><author><name sortKey="Cif, Laura" sort="Cif, Laura" uniqKey="Cif L" first="Laura" last="Cif">Laura Cif</name></author><author><name sortKey="Biolsi, Brigitte" sort="Biolsi, Brigitte" uniqKey="Biolsi B" first="Brigitte" last="Biolsi">Brigitte Biolsi</name></author><author><name sortKey="Gavarini, Sophie" sort="Gavarini, Sophie" uniqKey="Gavarini S" first="Sophie" last="Gavarini">Sophie Gavarini</name></author><author><name sortKey="Saux, Aude" sort="Saux, Aude" uniqKey="Saux A" first="Aude" last="Saux">Aude Saux</name></author><author><name sortKey="Robles, Santiago Gil" sort="Robles, Santiago Gil" 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Fonctionnelle, Montpellier</wicri:regionArea><placeName><settlement type="city">Montpellier</settlement></placeName></affiliation></author><author><name sortKey="Biolsi, Brigitte" sort="Biolsi, Brigitte" uniqKey="Biolsi B" first="Brigitte" last="Biolsi">Brigitte Biolsi</name><affiliation wicri:level="1"><country xml:lang="fr">France</country><wicri:regionArea>CHRU Montpellier, Service de Neurochirurgie, Montpellier</wicri:regionArea><placeName><settlement type="city">Montpellier</settlement></placeName></affiliation></author><author><name sortKey="Gavarini, Sophie" sort="Gavarini, Sophie" uniqKey="Gavarini S" first="Sophie" last="Gavarini">Sophie Gavarini</name><affiliation wicri:level="1"><country xml:lang="fr">France</country><wicri:regionArea>INSERM, U661, Montpellier</wicri:regionArea><placeName><settlement type="city">Montpellier</settlement></placeName></affiliation><affiliation wicri:level="1"><country xml:lang="fr">France</country><wicri:regionArea>Université de Montpellier I, 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type="city">Montpellier</settlement></placeName></affiliation></author><author><name sortKey="Vasques, Xavier" sort="Vasques, Xavier" uniqKey="Vasques X" first="Xavier" last="Vasques">Xavier Vasques</name><affiliation wicri:level="1"><country xml:lang="fr">France</country><wicri:regionArea>INSERM, U661, Montpellier</wicri:regionArea><placeName><settlement type="city">Montpellier</settlement></placeName></affiliation><affiliation wicri:level="1"><country xml:lang="fr">France</country><wicri:regionArea>Université de Montpellier I, CNRS UMR5203, Institut de Génomique Fonctionnelle, Montpellier</wicri:regionArea><placeName><settlement type="city">Montpellier</settlement></placeName></affiliation></author><author><name sortKey="Coubes, Philippe" sort="Coubes, Philippe" uniqKey="Coubes P" first="Philippe" last="Coubes">Philippe Coubes</name><affiliation wicri:level="1"><country xml:lang="fr">France</country><wicri:regionArea>CHRU Montpellier, Service de Neurochirurgie, 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Disord.</title><idno type="ISSN">0885-3185</idno><idno type="eISSN">1531-8257</idno><imprint><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><pubPlace>Hoboken</pubPlace><date type="published" when="2007-10-31">2007-10-31</date><biblScope unit="vol">22</biblScope><biblScope unit="issue">14</biblScope><biblScope unit="page" from="2126">2126</biblScope><biblScope unit="page" to="2129">2129</biblScope></imprint><idno type="ISSN">0885-3185</idno></series><idno type="istex">FAB3446595192B831E717048AC9CE33BB3E6A43A</idno><idno type="DOI">10.1002/mds.21723</idno><idno type="ArticleID">MDS21723</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0885-3185</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>DBS</term><term>Lesch–Nyhan disease</term><term>dystonia</term><term>internal pallidum</term><term>self injury</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">The Lesch–Nyhan syndrome is an X‐linked recessive disorder caused by a deficiency in hypoxanthine–guanine phosphoribosyl transferase, a purine salvage enzyme. Affected individuals exhibit a characteristic neurobehavioral disorder with delayed acquisition of motor skills, dystonia, severe self‐mutilations, and aggressive behavior. Deep brain stimulation has been previously proposed for controlling isolated involuntary movements and psychiatric disorders. We applied a double bilateral simultaneous stimulation to limbic and motor internal pallidum in one patient for controlling both behavioral and movement disorders, respectively. The injurious compulsions disappeared; dystonia and dyskinesia were decreased at 28 months follow‐up. © 2007 Movement Disorder Society</div></front></TEI></ISTEX><PubMed><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Antero-ventral internal pallidum stimulation improves behavioral disorders in Lesch-Nyhan disease.</title><author><name sortKey="Cif, Laura" sort="Cif, Laura" uniqKey="Cif L" first="Laura" last="Cif">Laura Cif</name><affiliation wicri:level="1"><nlm:affiliation>CHRU Montpellier, Service de Neurochirurgie, Montpellier, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>CHRU Montpellier, Service de Neurochirurgie, Montpellier</wicri:regionArea><placeName><settlement type="city">Montpellier</settlement></placeName></affiliation></author><author><name sortKey="Biolsi, Brigitte" sort="Biolsi, Brigitte" uniqKey="Biolsi B" first="Brigitte" last="Biolsi">Brigitte Biolsi</name></author><author><name sortKey="Gavarini, Sophie" sort="Gavarini, Sophie" uniqKey="Gavarini S" first="Sophie" last="Gavarini">Sophie Gavarini</name></author><author><name sortKey="Saux, Aude" sort="Saux, Aude" uniqKey="Saux A" first="Aude" last="Saux">Aude Saux</name></author><author><name sortKey="Robles, Santiago Gil" sort="Robles, Santiago Gil" uniqKey="Robles S" first="Santiago Gil" last="Robles">Santiago Gil Robles</name></author><author><name sortKey="Tancu, Cornel" sort="Tancu, Cornel" uniqKey="Tancu C" first="Cornel" last="Tancu">Cornel Tancu</name></author><author><name sortKey="Vasques, Xavier" sort="Vasques, Xavier" uniqKey="Vasques X" first="Xavier" last="Vasques">Xavier Vasques</name></author><author><name sortKey="Coubes, Philippe" sort="Coubes, Philippe" uniqKey="Coubes P" first="Philippe" last="Coubes">Philippe Coubes</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2007">2007</date><idno type="doi">10.1002/mds.21723</idno><idno type="RBID">pubmed:17853483</idno><idno type="pmid">17853483</idno><idno type="wicri:Area/PubMed/Corpus">002528</idno><idno type="wicri:Area/PubMed/Curation">002528</idno><idno type="wicri:Area/PubMed/Checkpoint">002977</idno><idno type="wicri:Area/Ncbi/Merge">001E31</idno><idno type="wicri:Area/Ncbi/Curation">001E31</idno><idno type="wicri:Area/Ncbi/Checkpoint">001E31</idno><idno type="wicri:doubleKey">0885-3185:2007:Cif L:antero:ventral:internal</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Antero-ventral internal pallidum stimulation improves behavioral disorders in Lesch-Nyhan disease.</title><author><name sortKey="Cif, Laura" sort="Cif, Laura" uniqKey="Cif L" first="Laura" last="Cif">Laura Cif</name><affiliation wicri:level="1"><nlm:affiliation>CHRU Montpellier, Service de Neurochirurgie, Montpellier, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>CHRU Montpellier, Service de Neurochirurgie, Montpellier</wicri:regionArea><placeName><settlement type="city">Montpellier</settlement></placeName></affiliation></author><author><name sortKey="Biolsi, Brigitte" sort="Biolsi, Brigitte" uniqKey="Biolsi B" first="Brigitte" last="Biolsi">Brigitte Biolsi</name></author><author><name sortKey="Gavarini, Sophie" sort="Gavarini, Sophie" uniqKey="Gavarini S" first="Sophie" last="Gavarini">Sophie Gavarini</name></author><author><name sortKey="Saux, Aude" sort="Saux, Aude" uniqKey="Saux A" first="Aude" last="Saux">Aude Saux</name></author><author><name sortKey="Robles, Santiago Gil" sort="Robles, Santiago Gil" uniqKey="Robles S" first="Santiago Gil" last="Robles">Santiago Gil Robles</name></author><author><name sortKey="Tancu, Cornel" sort="Tancu, Cornel" uniqKey="Tancu C" first="Cornel" last="Tancu">Cornel Tancu</name></author><author><name sortKey="Vasques, Xavier" sort="Vasques, Xavier" uniqKey="Vasques X" first="Xavier" last="Vasques">Xavier Vasques</name></author><author><name sortKey="Coubes, Philippe" sort="Coubes, Philippe" uniqKey="Coubes P" first="Philippe" last="Coubes">Philippe Coubes</name></author></analytic><series><title level="j">Movement disorders : official journal of the Movement Disorder Society</title><idno type="ISSN">0885-3185</idno><imprint><date when="2007" type="published">2007</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adolescent</term><term>Behavioral Symptoms (etiology)</term><term>Behavioral Symptoms (therapy)</term><term>Electric Stimulation Therapy (methods)</term><term>Globus Pallidus (physiopathology)</term><term>Globus Pallidus (radiation effects)</term><term>Humans</term><term>Lesch-Nyhan Syndrome (complications)</term><term>Male</term></keywords><keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Lesch-Nyhan Syndrome</term></keywords><keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Behavioral Symptoms</term></keywords><keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Electric Stimulation Therapy</term></keywords><keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Globus Pallidus</term></keywords><keywords scheme="MESH" qualifier="radiation effects" xml:lang="en"><term>Globus Pallidus</term></keywords><keywords scheme="MESH" qualifier="therapy" xml:lang="en"><term>Behavioral Symptoms</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adolescent</term><term>Humans</term><term>Male</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">The Lesch-Nyhan syndrome is an X-linked recessive disorder caused by a deficiency in hypoxanthine-guanine phosphoribosyl transferase, a purine salvage enzyme. Affected individuals exhibit a characteristic neurobehavioral disorder with delayed acquisition of motor skills, dystonia, severe self-mutilations, and aggressive behavior. Deep brain stimulation has been previously proposed for controlling isolated involuntary movements and psychiatric disorders. We applied a double bilateral simultaneous stimulation to limbic and motor internal pallidum in one patient for controlling both behavioral and movement disorders, respectively. The injurious compulsions disappeared; dystonia and dyskinesia were decreased at 28 months follow-up.</div></front></TEI></PubMed></double></record>Pour manipuler ce document sous Unix (Dilib)
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