Health‐related quality of life in sporadic adult‐onset ataxia
Identifieur interne : 003D44 ( Main/Merge ); précédent : 003D43; suivant : 003D45Health‐related quality of life in sporadic adult‐onset ataxia
Auteurs : Michael Abele [Allemagne] ; Thomas Klockgether [Allemagne]Source :
- Movement Disorders [ 0885-3185 ] ; 2007-02-15.
English descriptors
- KwdEn :
- MESH :
- etiology : Depression.
- physiopathology : Ataxia.
- psychology : Ataxia.
- Adult, Aged, Disability Evaluation, Female, Health Status, Humans, Male, Middle Aged, Quality of Life, Questionnaires, Sickness Impact Profile.
Abstract
Despite progressive disability in sporadic adult‐onset ataxia (SAOA), little is known about patients' assessment of their ataxic disorder and its impact on health‐related quality of life (Hr‐QoL). This study investigated Hr‐QoL by means of the following self‐administered scales: Pittsburgh Sleep Quality Index, Epworth Sleepiness Scale, Beck Depression Inventory (BDI), and the Medical Outcome Study Short Form (SF‐36). Twenty‐two unselected ataxia patients were included. Sleep‐related complaints were found in 9 (41%) of 22 and symptoms of depression in 6 (38%) of 16 patients. Compared to a large german control group, SAOA patients had lower scores in all SF‐36 dimensions except for bodily pain. The greatest impairment was found in the domain physical functioning, followed by the domains social functioning and role limitations (emotional problems). There was a significant negative correlation of all nonmotor SF‐36 dimensions with the BDI score. Walking aid dependency was significantly correlated with poorer health status perception in several motor and nonmotor domains. In addition, impaired sleep quality was correlated with an impaired general health perception and with bodily pain. The study demonstrates a great impact of SAOA on Hr‐QoL. Adequate treatment of depression, motor disability, and impaired sleep quality is essential to improve Hr‐QoL in ataxic patients. © 2006 Movement Disorder Society
Url:
DOI: 10.1002/mds.21265
Links toward previous steps (curation, corpus...)
- to stream Istex, to step Corpus: 001D71
- to stream Istex, to step Curation: 001D71
- to stream Istex, to step Checkpoint: 001930
- to stream PubMed, to step Corpus: 002953
- to stream PubMed, to step Curation: 002953
- to stream PubMed, to step Checkpoint: 002794
- to stream Ncbi, to step Merge: 001986
- to stream Ncbi, to step Curation: 001986
- to stream Ncbi, to step Checkpoint: 001986
Links to Exploration step
ISTEX:6A41070E6819C3DBAAA543053EDBC57F7A5024E8Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Health‐related quality of life in sporadic adult‐onset ataxia</title>
<author><name sortKey="Abele, Michael" sort="Abele, Michael" uniqKey="Abele M" first="Michael" last="Abele">Michael Abele</name>
</author>
<author><name sortKey="Klockgether, Thomas" sort="Klockgether, Thomas" uniqKey="Klockgether T" first="Thomas" last="Klockgether">Thomas Klockgether</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">ISTEX</idno>
<idno type="RBID">ISTEX:6A41070E6819C3DBAAA543053EDBC57F7A5024E8</idno>
<date when="2007" year="2007">2007</date>
<idno type="doi">10.1002/mds.21265</idno>
<idno type="url">https://api.istex.fr/document/6A41070E6819C3DBAAA543053EDBC57F7A5024E8/fulltext/pdf</idno>
<idno type="wicri:Area/Istex/Corpus">001D71</idno>
<idno type="wicri:Area/Istex/Curation">001D71</idno>
<idno type="wicri:Area/Istex/Checkpoint">001930</idno>
<idno type="wicri:doubleKey">0885-3185:2007:Abele M:health:related:quality</idno>
<idno type="wicri:source">PubMed</idno>
<idno type="RBID">pubmed:17149704</idno>
<idno type="wicri:Area/PubMed/Corpus">002953</idno>
<idno type="wicri:Area/PubMed/Curation">002953</idno>
<idno type="wicri:Area/PubMed/Checkpoint">002794</idno>
<idno type="wicri:Area/Ncbi/Merge">001986</idno>
<idno type="wicri:Area/Ncbi/Curation">001986</idno>
<idno type="wicri:Area/Ncbi/Checkpoint">001986</idno>
<idno type="wicri:doubleKey">0885-3185:2007:Abele M:health:related:quality</idno>
<idno type="wicri:Area/Main/Merge">003D44</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Health‐related quality of life in sporadic adult‐onset ataxia</title>
<author><name sortKey="Abele, Michael" sort="Abele, Michael" uniqKey="Abele M" first="Michael" last="Abele">Michael Abele</name>
<affiliation wicri:level="1"><country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Department of Neurology, University of Bonn</wicri:regionArea>
<wicri:noRegion>University of Bonn</wicri:noRegion>
<wicri:noRegion>University of Bonn</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Klockgether, Thomas" sort="Klockgether, Thomas" uniqKey="Klockgether T" first="Thomas" last="Klockgether">Thomas Klockgether</name>
<affiliation wicri:level="1"><country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Department of Neurology, University of Bonn</wicri:regionArea>
<wicri:noRegion>University of Bonn</wicri:noRegion>
<wicri:noRegion>University of Bonn</wicri:noRegion>
</affiliation>
</author>
</analytic>
<monogr></monogr>
<series><title level="j">Movement Disorders</title>
<title level="j" type="sub">Official Journal of the Movement Disorder Society</title>
<title level="j" type="abbrev">Mov. Disord.</title>
<idno type="ISSN">0885-3185</idno>
<idno type="eISSN">1531-8257</idno>
<imprint><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher>
<pubPlace>Hoboken</pubPlace>
<date type="published" when="2007-02-15">2007-02-15</date>
<biblScope unit="vol">22</biblScope>
<biblScope unit="issue">3</biblScope>
<biblScope unit="page" from="348">348</biblScope>
<biblScope unit="page" to="352">352</biblScope>
</imprint>
<idno type="ISSN">0885-3185</idno>
</series>
<idno type="istex">6A41070E6819C3DBAAA543053EDBC57F7A5024E8</idno>
<idno type="DOI">10.1002/mds.21265</idno>
<idno type="ArticleID">MDS21265</idno>
</biblStruct>
</sourceDesc>
<seriesStmt><idno type="ISSN">0885-3185</idno>
</seriesStmt>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term>
<term>Aged</term>
<term>Ataxia (physiopathology)</term>
<term>Ataxia (psychology)</term>
<term>Depression (etiology)</term>
<term>Disability Evaluation</term>
<term>Female</term>
<term>Health Status</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Quality of Life</term>
<term>Questionnaires</term>
<term>Sickness Impact Profile</term>
<term>depression</term>
<term>health‐related quality of life</term>
<term>sleep</term>
<term>sporadic ataxia</term>
</keywords>
<keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Depression</term>
</keywords>
<keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Ataxia</term>
</keywords>
<keywords scheme="MESH" qualifier="psychology" xml:lang="en"><term>Ataxia</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Adult</term>
<term>Aged</term>
<term>Disability Evaluation</term>
<term>Female</term>
<term>Health Status</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Quality of Life</term>
<term>Questionnaires</term>
<term>Sickness Impact Profile</term>
</keywords>
</textClass>
<langUsage><language ident="en">en</language>
</langUsage>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">Despite progressive disability in sporadic adult‐onset ataxia (SAOA), little is known about patients' assessment of their ataxic disorder and its impact on health‐related quality of life (Hr‐QoL). This study investigated Hr‐QoL by means of the following self‐administered scales: Pittsburgh Sleep Quality Index, Epworth Sleepiness Scale, Beck Depression Inventory (BDI), and the Medical Outcome Study Short Form (SF‐36). Twenty‐two unselected ataxia patients were included. Sleep‐related complaints were found in 9 (41%) of 22 and symptoms of depression in 6 (38%) of 16 patients. Compared to a large german control group, SAOA patients had lower scores in all SF‐36 dimensions except for bodily pain. The greatest impairment was found in the domain physical functioning, followed by the domains social functioning and role limitations (emotional problems). There was a significant negative correlation of all nonmotor SF‐36 dimensions with the BDI score. Walking aid dependency was significantly correlated with poorer health status perception in several motor and nonmotor domains. In addition, impaired sleep quality was correlated with an impaired general health perception and with bodily pain. The study demonstrates a great impact of SAOA on Hr‐QoL. Adequate treatment of depression, motor disability, and impaired sleep quality is essential to improve Hr‐QoL in ataxic patients. © 2006 Movement Disorder Society</div>
</front>
</TEI>
<double doi="10.1002/mds.21265"><ISTEX><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Health‐related quality of life in sporadic adult‐onset ataxia</title>
<author><name sortKey="Abele, Michael" sort="Abele, Michael" uniqKey="Abele M" first="Michael" last="Abele">Michael Abele</name>
</author>
<author><name sortKey="Klockgether, Thomas" sort="Klockgether, Thomas" uniqKey="Klockgether T" first="Thomas" last="Klockgether">Thomas Klockgether</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">ISTEX</idno>
<idno type="RBID">ISTEX:6A41070E6819C3DBAAA543053EDBC57F7A5024E8</idno>
<date when="2007" year="2007">2007</date>
<idno type="doi">10.1002/mds.21265</idno>
<idno type="url">https://api.istex.fr/document/6A41070E6819C3DBAAA543053EDBC57F7A5024E8/fulltext/pdf</idno>
<idno type="wicri:Area/Istex/Corpus">001D71</idno>
<idno type="wicri:Area/Istex/Curation">001D71</idno>
<idno type="wicri:Area/Istex/Checkpoint">001930</idno>
<idno type="wicri:doubleKey">0885-3185:2007:Abele M:health:related:quality</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Health‐related quality of life in sporadic adult‐onset ataxia</title>
<author><name sortKey="Abele, Michael" sort="Abele, Michael" uniqKey="Abele M" first="Michael" last="Abele">Michael Abele</name>
<affiliation wicri:level="1"><country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Department of Neurology, University of Bonn</wicri:regionArea>
<wicri:noRegion>University of Bonn</wicri:noRegion>
<wicri:noRegion>University of Bonn</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Klockgether, Thomas" sort="Klockgether, Thomas" uniqKey="Klockgether T" first="Thomas" last="Klockgether">Thomas Klockgether</name>
<affiliation wicri:level="1"><country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Department of Neurology, University of Bonn</wicri:regionArea>
<wicri:noRegion>University of Bonn</wicri:noRegion>
<wicri:noRegion>University of Bonn</wicri:noRegion>
</affiliation>
</author>
</analytic>
<monogr></monogr>
<series><title level="j">Movement Disorders</title>
<title level="j" type="sub">Official Journal of the Movement Disorder Society</title>
<title level="j" type="abbrev">Mov. Disord.</title>
<idno type="ISSN">0885-3185</idno>
<idno type="eISSN">1531-8257</idno>
<imprint><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher>
<pubPlace>Hoboken</pubPlace>
<date type="published" when="2007-02-15">2007-02-15</date>
<biblScope unit="vol">22</biblScope>
<biblScope unit="issue">3</biblScope>
<biblScope unit="page" from="348">348</biblScope>
<biblScope unit="page" to="352">352</biblScope>
</imprint>
<idno type="ISSN">0885-3185</idno>
</series>
<idno type="istex">6A41070E6819C3DBAAA543053EDBC57F7A5024E8</idno>
<idno type="DOI">10.1002/mds.21265</idno>
<idno type="ArticleID">MDS21265</idno>
</biblStruct>
</sourceDesc>
<seriesStmt><idno type="ISSN">0885-3185</idno>
</seriesStmt>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>depression</term>
<term>health‐related quality of life</term>
<term>sleep</term>
<term>sporadic ataxia</term>
</keywords>
</textClass>
<langUsage><language ident="en">en</language>
</langUsage>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">Despite progressive disability in sporadic adult‐onset ataxia (SAOA), little is known about patients' assessment of their ataxic disorder and its impact on health‐related quality of life (Hr‐QoL). This study investigated Hr‐QoL by means of the following self‐administered scales: Pittsburgh Sleep Quality Index, Epworth Sleepiness Scale, Beck Depression Inventory (BDI), and the Medical Outcome Study Short Form (SF‐36). Twenty‐two unselected ataxia patients were included. Sleep‐related complaints were found in 9 (41%) of 22 and symptoms of depression in 6 (38%) of 16 patients. Compared to a large german control group, SAOA patients had lower scores in all SF‐36 dimensions except for bodily pain. The greatest impairment was found in the domain physical functioning, followed by the domains social functioning and role limitations (emotional problems). There was a significant negative correlation of all nonmotor SF‐36 dimensions with the BDI score. Walking aid dependency was significantly correlated with poorer health status perception in several motor and nonmotor domains. In addition, impaired sleep quality was correlated with an impaired general health perception and with bodily pain. The study demonstrates a great impact of SAOA on Hr‐QoL. Adequate treatment of depression, motor disability, and impaired sleep quality is essential to improve Hr‐QoL in ataxic patients. © 2006 Movement Disorder Society</div>
</front>
</TEI>
</ISTEX>
<PubMed><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Health-related quality of life in sporadic adult-onset ataxia.</title>
<author><name sortKey="Abele, Michael" sort="Abele, Michael" uniqKey="Abele M" first="Michael" last="Abele">Michael Abele</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Neurology, University of Bonn, Germany. michael.abele@uni-bonn.de</nlm:affiliation>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Department of Neurology, University of Bonn</wicri:regionArea>
<wicri:noRegion>University of Bonn</wicri:noRegion>
<wicri:noRegion>University of Bonn</wicri:noRegion>
<wicri:noRegion>University of Bonn</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Klockgether, Thomas" sort="Klockgether, Thomas" uniqKey="Klockgether T" first="Thomas" last="Klockgether">Thomas Klockgether</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PubMed</idno>
<date when="2007">2007</date>
<idno type="doi">10.1002/mds.21265</idno>
<idno type="RBID">pubmed:17149704</idno>
<idno type="pmid">17149704</idno>
<idno type="wicri:Area/PubMed/Corpus">002953</idno>
<idno type="wicri:Area/PubMed/Curation">002953</idno>
<idno type="wicri:Area/PubMed/Checkpoint">002794</idno>
<idno type="wicri:Area/Ncbi/Merge">001986</idno>
<idno type="wicri:Area/Ncbi/Curation">001986</idno>
<idno type="wicri:Area/Ncbi/Checkpoint">001986</idno>
<idno type="wicri:doubleKey">0885-3185:2007:Abele M:health:related:quality</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en">Health-related quality of life in sporadic adult-onset ataxia.</title>
<author><name sortKey="Abele, Michael" sort="Abele, Michael" uniqKey="Abele M" first="Michael" last="Abele">Michael Abele</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Neurology, University of Bonn, Germany. michael.abele@uni-bonn.de</nlm:affiliation>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Department of Neurology, University of Bonn</wicri:regionArea>
<wicri:noRegion>University of Bonn</wicri:noRegion>
<wicri:noRegion>University of Bonn</wicri:noRegion>
<wicri:noRegion>University of Bonn</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Klockgether, Thomas" sort="Klockgether, Thomas" uniqKey="Klockgether T" first="Thomas" last="Klockgether">Thomas Klockgether</name>
</author>
</analytic>
<series><title level="j">Movement disorders : official journal of the Movement Disorder Society</title>
<idno type="ISSN">0885-3185</idno>
<imprint><date when="2007" type="published">2007</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term>
<term>Aged</term>
<term>Ataxia (physiopathology)</term>
<term>Ataxia (psychology)</term>
<term>Depression (etiology)</term>
<term>Disability Evaluation</term>
<term>Female</term>
<term>Health Status</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Quality of Life</term>
<term>Questionnaires</term>
<term>Sickness Impact Profile</term>
</keywords>
<keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Depression</term>
</keywords>
<keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Ataxia</term>
</keywords>
<keywords scheme="MESH" qualifier="psychology" xml:lang="en"><term>Ataxia</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Adult</term>
<term>Aged</term>
<term>Disability Evaluation</term>
<term>Female</term>
<term>Health Status</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Quality of Life</term>
<term>Questionnaires</term>
<term>Sickness Impact Profile</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">Despite progressive disability in sporadic adult-onset ataxia (SAOA), little is known about patients' assessment of their ataxic disorder and its impact on health-related quality of life (Hr-QoL). This study investigated Hr-QoL by means of the following self-administered scales: Pittsburgh Sleep Quality Index, Epworth Sleepiness Scale, Beck Depression Inventory (BDI), and the Medical Outcome Study Short Form (SF-36). Twenty-two unselected ataxia patients were included. Sleep-related complaints were found in 9 (41%) of 22 and symptoms of depression in 6 (38%) of 16 patients. Compared to a large german control group, SAOA patients had lower scores in all SF-36 dimensions except for bodily pain. The greatest impairment was found in the domain physical functioning, followed by the domains social functioning and role limitations (emotional problems). There was a significant negative correlation of all nonmotor SF-36 dimensions with the BDI score. Walking aid dependency was significantly correlated with poorer health status perception in several motor and nonmotor domains. In addition, impaired sleep quality was correlated with an impaired general health perception and with bodily pain. The study demonstrates a great impact of SAOA on Hr-QoL. Adequate treatment of depression, motor disability, and impaired sleep quality is essential to improve Hr-QoL in ataxic patients.</div>
</front>
</TEI>
</PubMed>
</double>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Santé/explor/MovDisordV3/Data/Main/Merge
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 003D44 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Merge/biblio.hfd -nk 003D44 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Wicri/Santé |area= MovDisordV3 |flux= Main |étape= Merge |type= RBID |clé= ISTEX:6A41070E6819C3DBAAA543053EDBC57F7A5024E8 |texte= Health‐related quality of life in sporadic adult‐onset ataxia }}
This area was generated with Dilib version V0.6.23. |