Cataplexy Features in Childhood Narcolepsy
Identifieur interne : 003941 ( Main/Merge ); précédent : 003940; suivant : 003942Cataplexy Features in Childhood Narcolepsy
Auteurs : Leonardo Serra [Italie, Chili] ; Pasquale Montagna [Italie] ; Emmanuel Mignot [États-Unis] ; Elio Lugaresi [Italie] ; Giuseppe Plazzi [Italie]Source :
- Movement disorders [ 0885-3185 ] ; 2008.
Descripteurs français
- Pascal (Inist)
- Wicri :
- topic : Enfant.
English descriptors
- KwdEn :
Abstract
Cataplexy, the hallmark of narcolepsy, has been well characterized in adults but not in children. This study systematically used structured clinical assessments and video-recordings (49 episodes in eight cases) to evaluate cataplexy in 23 patients diagnosed before the age of 18 years. Forty-three percent of patients had falls as part of their attacks. During cataplexy knees, head, and jaw were the most frequently compromised body segments; eyelids, arms, and trunk being less commonly involved. More rarely, blurred vision, slurred speech, irregular breathing, or a sudden loss of smiling mimics were reported. One-third of the sample presented with a previously unrecognized description of cataplexy that we coined "cataplectic facies," consisting of a state of semipermanent eyelid and jaw weakness, on which partial or complete cataplectic attacks were superimposed. The usual triggering emotions, such as laughter, joking, or anger, were not always present, especially when close to an abrupt onset, hampering diagnosis. Video-recordings of cataplectic attacks may be useful to document the attack, allowing a comparison with archived presentations.
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Pascal:08-0251869Le document en format XML
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Disorders Center, Department of Neurological Sciences, University of Bologna</wicri:noRegion></affiliation><affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Sleep Medicine Center, Pontifice Catholic University of Chile</s1><s2>Santiago</s2><s3>CHL</s3><sZ>1 aut.</sZ></inist:fA14><country>Chili</country><wicri:noRegion>Santiago</wicri:noRegion></affiliation></author><author><name sortKey="Montagna, Pasquale" sort="Montagna, Pasquale" uniqKey="Montagna P" first="Pasquale" last="Montagna">Pasquale Montagna</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Sleep Disorders Center, Department of Neurological Sciences, University of Bologna</s1><s3>ITA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ></inist:fA14><country>Italie</country><wicri:noRegion>Sleep Disorders Center, Department of Neurological Sciences, University of Bologna</wicri:noRegion></affiliation></author><author><name sortKey="Mignot, Emmanuel" sort="Mignot, Emmanuel" uniqKey="Mignot E" first="Emmanuel" last="Mignot">Emmanuel Mignot</name><affiliation wicri:level="2"><inist:fA14 i1="03"><s1>Center for Narcolepsy, Stanford University</s1><s2>California</s2><s3>USA</s3><sZ>3 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Lugaresi, Elio" sort="Lugaresi, Elio" uniqKey="Lugaresi E" first="Elio" last="Lugaresi">Elio Lugaresi</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Sleep Disorders Center, Department of Neurological Sciences, University of Bologna</s1><s3>ITA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ></inist:fA14><country>Italie</country><wicri:noRegion>Sleep Disorders Center, Department of Neurological Sciences, University of Bologna</wicri:noRegion></affiliation></author><author><name sortKey="Plazzi, Giuseppe" sort="Plazzi, Giuseppe" uniqKey="Plazzi G" first="Giuseppe" last="Plazzi">Giuseppe Plazzi</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Sleep Disorders Center, Department of Neurological Sciences, University of Bologna</s1><s3>ITA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ></inist:fA14><country>Italie</country><wicri:noRegion>Sleep Disorders Center, Department of Neurological Sciences, University of Bologna</wicri:noRegion></affiliation></author></analytic><series><title level="j" type="main">Movement disorders</title><title level="j" type="abbreviated">Mov. disord.</title><idno type="ISSN">0885-3185</idno><imprint><date when="2008">2008</date></imprint></series></biblStruct></sourceDesc><seriesStmt><title level="j" type="main">Movement disorders</title><title level="j" type="abbreviated">Mov. disord.</title><idno type="ISSN">0885-3185</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Cataplexy</term><term>Child</term><term>Narcolepsy</term><term>Nervous system diseases</term><term>Sleep</term></keywords><keywords scheme="Pascal" xml:lang="fr"><term>Narcolepsie</term><term>Pathologie du système nerveux</term><term>Cataplexie</term><term>Enfant</term><term>Sommeil</term></keywords><keywords scheme="Wicri" type="topic" xml:lang="fr"><term>Enfant</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Cataplexy, the hallmark of narcolepsy, has been well characterized in adults but not in children. This study systematically used structured clinical assessments and video-recordings (49 episodes in eight cases) to evaluate cataplexy in 23 patients diagnosed before the age of 18 years. Forty-three percent of patients had falls as part of their attacks. During cataplexy knees, head, and jaw were the most frequently compromised body segments; eyelids, arms, and trunk being less commonly involved. More rarely, blurred vision, slurred speech, irregular breathing, or a sudden loss of smiling mimics were reported. One-third of the sample presented with a previously unrecognized description of cataplexy that we coined "cataplectic facies," consisting of a state of semipermanent eyelid and jaw weakness, on which partial or complete cataplectic attacks were superimposed. The usual triggering emotions, such as laughter, joking, or anger, were not always present, especially when close to an abrupt onset, hampering diagnosis. Video-recordings of cataplectic attacks may be useful to document the attack, allowing a comparison with archived presentations.</div></front></TEI><affiliations><list><country><li>Chili</li><li>Italie</li><li>États-Unis</li></country><region><li>Californie</li></region></list><tree><country name="Italie"><noRegion><name sortKey="Serra, Leonardo" sort="Serra, Leonardo" uniqKey="Serra L" first="Leonardo" last="Serra">Leonardo Serra</name></noRegion><name sortKey="Lugaresi, Elio" sort="Lugaresi, Elio" uniqKey="Lugaresi E" first="Elio" last="Lugaresi">Elio Lugaresi</name><name sortKey="Montagna, Pasquale" sort="Montagna, Pasquale" uniqKey="Montagna P" first="Pasquale" last="Montagna">Pasquale Montagna</name><name sortKey="Plazzi, Giuseppe" sort="Plazzi, Giuseppe" uniqKey="Plazzi G" first="Giuseppe" last="Plazzi">Giuseppe Plazzi</name></country><country name="Chili"><noRegion><name sortKey="Serra, Leonardo" sort="Serra, Leonardo" uniqKey="Serra L" first="Leonardo" last="Serra">Leonardo Serra</name></noRegion></country><country name="États-Unis"><region name="Californie"><name sortKey="Mignot, Emmanuel" sort="Mignot, Emmanuel" uniqKey="Mignot E" first="Emmanuel" last="Mignot">Emmanuel Mignot</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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