Bradykinesia, Muscle Weakness and Reduced Muscle Power in Parkinson's Disease
Identifieur interne : 003060 ( Main/Merge ); précédent : 003059; suivant : 003061Bradykinesia, Muscle Weakness and Reduced Muscle Power in Parkinson's Disease
Auteurs : Natalie E. Allen [Australie] ; Colleen G. Canning [Australie] ; Catherine Sherrington [Australie] ; Victor S. C. Fung [Australie]Source :
- Movement disorders [ 0885-3185 ] ; 2009.
Descripteurs français
- Pascal (Inist)
English descriptors
- KwdEn :
Abstract
Muscle power (force velocity) could clarify the relationship between weakness and bradykinesia in Parkinson's disease (PD). The aims of this study were to determine if patients with PD were weaker and/or less powerful in their leg extensor muscles than a neurologically normal control group and to determine the relative contributions of force and movement velocity/bradykinesia to muscle power in PD. Forty patients with PD and 40 controls were assessed. Strength in Newtons (N) was measured as the heaviest load the participant could lift. Power in Watts (W) was measured by having the participant perform lifts as fast as possible. The PD group were 172 N weaker (95% CI 28-315) and 124 W less powerful at peak power (95% CI 32-216) than controls. However, velocity at maximal power was only reduced compared with controls when lifting light to medium loads. When lifting heavy loads bradykinesia was no longer apparent in the PD group. These results suggest that reduced muscle power in PD at lighter loads arises from weakness and bradykinesia combined, but at heavier loads arises only from weakness. The absence of bradykinesia in the PD group when lifting heavy loads warrants further investigation.
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Canning</name><affiliation wicri:level="3"><inist:fA14 i1="01"><s1>Neurological Rehabilitation Research Group, Faculty of Health Sciences, The University of Sydney</s1><s2>Sydney</s2><s3>AUS</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ></inist:fA14><country>Australie</country><placeName><settlement type="city">Sydney</settlement></placeName></affiliation></author><author><name sortKey="Sherrington, Catherine" sort="Sherrington, Catherine" uniqKey="Sherrington C" first="Catherine" last="Sherrington">Catherine Sherrington</name><affiliation wicri:level="3"><inist:fA14 i1="02"><s1>The George Institute for International Health, The University of Sydney</s1><s2>Sydney</s2><s3>AUS</s3><sZ>3 aut.</sZ></inist:fA14><country>Australie</country><placeName><settlement type="city">Sydney</settlement></placeName></affiliation></author><author><name sortKey="Fung, Victor S C" sort="Fung, Victor S C" uniqKey="Fung V" first="Victor S. C." last="Fung">Victor S. C. 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Allen</name><affiliation wicri:level="3"><inist:fA14 i1="01"><s1>Neurological Rehabilitation Research Group, Faculty of Health Sciences, The University of Sydney</s1><s2>Sydney</s2><s3>AUS</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ></inist:fA14><country>Australie</country><placeName><settlement type="city">Sydney</settlement></placeName></affiliation></author><author><name sortKey="Canning, Colleen G" sort="Canning, Colleen G" uniqKey="Canning C" first="Colleen G." last="Canning">Colleen G. Canning</name><affiliation wicri:level="3"><inist:fA14 i1="01"><s1>Neurological Rehabilitation Research Group, Faculty of Health Sciences, The University of Sydney</s1><s2>Sydney</s2><s3>AUS</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ></inist:fA14><country>Australie</country><placeName><settlement type="city">Sydney</settlement></placeName></affiliation></author><author><name sortKey="Sherrington, Catherine" sort="Sherrington, Catherine" uniqKey="Sherrington C" first="Catherine" last="Sherrington">Catherine Sherrington</name><affiliation wicri:level="3"><inist:fA14 i1="02"><s1>The George Institute for International Health, The University of Sydney</s1><s2>Sydney</s2><s3>AUS</s3><sZ>3 aut.</sZ></inist:fA14><country>Australie</country><placeName><settlement type="city">Sydney</settlement></placeName></affiliation></author><author><name sortKey="Fung, Victor S C" sort="Fung, Victor S C" uniqKey="Fung V" first="Victor S. C." last="Fung">Victor S. C. Fung</name><affiliation wicri:level="3"><inist:fA14 i1="03"><s1>Movement Disorder Unit, Department of Neurology, Westmead Hospital</s1><s2>Sydney</s2><s3>AUS</s3><sZ>4 aut.</sZ></inist:fA14><country>Australie</country><placeName><settlement type="city">Sydney</settlement></placeName></affiliation></author></analytic><series><title level="j" type="main">Movement disorders</title><title level="j" type="abbreviated">Mov. disord.</title><idno type="ISSN">0885-3185</idno><imprint><date when="2009">2009</date></imprint></series></biblStruct></sourceDesc><seriesStmt><title level="j" type="main">Movement disorders</title><title level="j" type="abbreviated">Mov. disord.</title><idno type="ISSN">0885-3185</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Nervous system diseases</term><term>Parkinson disease</term></keywords><keywords scheme="Pascal" xml:lang="fr"><term>Maladie de Parkinson</term><term>Pathologie du système nerveux</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Muscle power (force velocity) could clarify the relationship between weakness and bradykinesia in Parkinson's disease (PD). The aims of this study were to determine if patients with PD were weaker and/or less powerful in their leg extensor muscles than a neurologically normal control group and to determine the relative contributions of force and movement velocity/bradykinesia to muscle power in PD. Forty patients with PD and 40 controls were assessed. Strength in Newtons (N) was measured as the heaviest load the participant could lift. Power in Watts (W) was measured by having the participant perform lifts as fast as possible. The PD group were 172 N weaker (95% CI 28-315) and 124 W less powerful at peak power (95% CI 32-216) than controls. However, velocity at maximal power was only reduced compared with controls when lifting light to medium loads. When lifting heavy loads bradykinesia was no longer apparent in the PD group. These results suggest that reduced muscle power in PD at lighter loads arises from weakness and bradykinesia combined, but at heavier loads arises only from weakness. The absence of bradykinesia in the PD group when lifting heavy loads warrants further investigation.</div></front></TEI><affiliations><list><country><li>Australie</li></country><settlement><li>Sydney</li></settlement></list><tree><country name="Australie"><noRegion><name sortKey="Allen, Natalie E" sort="Allen, Natalie E" uniqKey="Allen N" first="Natalie E." last="Allen">Natalie E. Allen</name></noRegion><name sortKey="Canning, Colleen G" sort="Canning, Colleen G" uniqKey="Canning C" first="Colleen G." last="Canning">Colleen G. Canning</name><name sortKey="Fung, Victor S C" sort="Fung, Victor S C" uniqKey="Fung V" first="Victor S. C." last="Fung">Victor S. C. Fung</name><name sortKey="Sherrington, Catherine" sort="Sherrington, Catherine" uniqKey="Sherrington C" first="Catherine" last="Sherrington">Catherine Sherrington</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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