MovDisordV3, Main, Merge, bibRecord, 002F19

Levosulpiride-Induced Movement Disorders

Identifieur interne : 002F19 ( Main/Merge ); précédent : 002F18; suivant : 002F20

Levosulpiride-Induced Movement Disorders

Auteurs : Hae-Won Shin [Corée du Sud] ; Mi J. Kim [Corée du Sud] ; Jong S. Kim [Corée du Sud] ; Myoung C. Lee [Corée du Sud] ; Sun J. Chung [Corée du Sud]

Source :

Movement disorders [ 0885-3185 ] ; 2009.

RBID : Pascal:10-0036284

Descripteurs français

Pascal (Inist)
- Abus de substance, Parkinsonisme, Dyskinésie, Tremblement, Pathologie du système nerveux, Lévosulpiride.

English descriptors

KwdEn :
- Dyskinesia, Levosulpiride, Nervous system diseases, Parkinsonism, Substance abuse, Tremor.

Abstract

Levosulpiride is a substituted benzamide that is widely used for the management of dyspepsia and emesis. However, little is known about levosulpiride-induced movement disorders (LIM). The aim of this study was to investigate the clinical characteristics of patients with LIM. Among 1 32 consecutive patients who were diagnosed with drug-induced movement disorders between January 2002 and March 2008, 91 patients with LIM were identified and their medical records reviewed. Seventy-eight (85.7%) patients were aged more than 60 years. The most common LIM was parkinsonism (LIP) (n = 85, 93.4%), followed by tardive dyskinesia (n = 9, 9.9%) and isolated tremor (n = 3, 3.3%). Twenty-one (24.7%) of the 85 patients with LIP were rated as Hoehn and Yahr stage III-V. The oro-lingual area was the only body part that was involved by tardive dyskinesia. LIM persisted after withdrawal of levosulpiride in 48.1 % of patients with LIP, 66.7% with dyskinesia, and none with isolated tremor. None of clinical and MRI features predicted the reversibility of LIP. Levosulpiride frequently causes drug-induced movement disorders, presenting mainly with LIP followed by lower face dyskinesia. The symptoms are often severe, and irreversible even after the withdrawal of levosulpiride. Physicians should be cautious in using levosulpiride, especially in elderly patients.

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Pascal:10-0036284

Le document en format XML

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<author><name sortKey="Shin, Hae Won" sort="Shin, Hae Won" uniqKey="Shin H" first="Hae-Won" last="Shin">Hae-Won Shin</name>
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<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a">Levosulpiride-Induced Movement Disorders</title>
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<author><name sortKey="Kim, Jong S" sort="Kim, Jong S" uniqKey="Kim J" first="Jong S." last="Kim">Jong S. Kim</name>
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<front><div type="abstract" xml:lang="en">Levosulpiride is a substituted benzamide that is widely used for the management of dyspepsia and emesis. However, little is known about levosulpiride-induced movement disorders (LIM). The aim of this study was to investigate the clinical characteristics of patients with LIM. Among 1 32 consecutive patients who were diagnosed with drug-induced movement disorders between January 2002 and March 2008, 91 patients with LIM were identified and their medical records reviewed. Seventy-eight (85.7%) patients were aged more than 60 years. The most common LIM was parkinsonism (LIP) (n = 85, 93.4%), followed by tardive dyskinesia (n = 9, 9.9%) and isolated tremor (n = 3, 3.3%). Twenty-one (24.7%) of the 85 patients with LIP were rated as Hoehn and Yahr stage III-V. The oro-lingual area was the only body part that was involved by tardive dyskinesia. LIM persisted after withdrawal of levosulpiride in 48.1 % of patients with LIP, 66.7% with dyskinesia, and none with isolated tremor. None of clinical and MRI features predicted the reversibility of LIP. Levosulpiride frequently causes drug-induced movement disorders, presenting mainly with LIP followed by lower face dyskinesia. The symptoms are often severe, and irreversible even after the withdrawal of levosulpiride. Physicians should be cautious in using levosulpiride, especially in elderly patients.</div>
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<tree><country name="Corée du Sud"><noRegion><name sortKey="Shin, Hae Won" sort="Shin, Hae Won" uniqKey="Shin H" first="Hae-Won" last="Shin">Hae-Won Shin</name>
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<name sortKey="Chung, Sun J" sort="Chung, Sun J" uniqKey="Chung S" first="Sun J." last="Chung">Sun J. Chung</name>
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<name sortKey="Kim, Mi J" sort="Kim, Mi J" uniqKey="Kim M" first="Mi J." last="Kim">Mi J. Kim</name>
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	Movement Disorders (revue)
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Movement Disorders (revue)

Levosulpiride-Induced Movement Disorders

Levosulpiride-Induced Movement Disorders

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri