A novel automatic method for monitoring Tourette motor tics through a wearable device
Identifieur interne : 002318 ( Main/Merge ); précédent : 002317; suivant : 002319A novel automatic method for monitoring Tourette motor tics through a wearable device
Auteurs : Michel Bernabei [Italie] ; Ezio Preatoni [Italie] ; Martin Mendez [Italie, Mexique] ; Luca Piccini [Italie] ; Mauro Porta [Italie] ; Giuseppe Andreoni [Italie]Source :
- Movement Disorders [ 0885-3185 ] ; 2010-09-15.
English descriptors
- KwdEn :
- Adolescent, Adult, Female, Humans, Male, Middle Aged, Monitoring, Ambulatory (instrumentation), Monitoring, Ambulatory (methods), Sensitivity and Specificity, Severity of Illness Index, Tics (diagnosis), Tics (physiopathology), Tourette Syndrome (diagnosis), Tourette Syndrome (physiopathology), Tourette syndrome, Video Recording, accelerometers, automatic tic detection, wearable monitoring.
- MESH :
- diagnosis : Tics, Tourette Syndrome.
- instrumentation : Monitoring, Ambulatory.
- methods : Monitoring, Ambulatory.
- physiopathology : Tics, Tourette Syndrome.
- Adolescent, Adult, Female, Humans, Male, Middle Aged, Sensitivity and Specificity, Severity of Illness Index, Video Recording.
Abstract
The aim of this study was to propose a novel automatic method for quantifying motor‐tics caused by the Tourette Syndrome (TS). In this preliminary report, the feasibility of the monitoring process was tested over a series of standard clinical trials in a population of 12 subjects affected by TS. A wearable instrument with an embedded three‐axial accelerometer was used to detect and classify motor tics during standing and walking activities. An algorithm was devised to analyze acceleration data by: eliminating noise; detecting peaks connected to pathological events; and classifying intensity and frequency of motor tics into quantitative scores. These indexes were compared with the video‐based ones provided by expert clinicians, which were taken as the gold‐standard. Sensitivity, specificity, and accuracy of tic detection were estimated, and an agreement analysis was performed through the least square regression and the Bland‐Altman test. The tic recognition algorithm showed sensitivity = 80.8% ± 8.5% (mean ± SD), specificity = 75.8% ± 17.3%, and accuracy = 80.5% ± 12.2%. The agreement study showed that automatic detection tended to overestimate the number of tics occurred. Although, it appeared this may be a systematic error due to the different recognition principles of the wearable and video‐based systems. Furthermore, there was substantial concurrency with the gold‐standard in estimating the severity indexes. The proposed methodology gave promising performances in terms of automatic motor‐tics detection and classification in a standard clinical context. The system may provide physicians with a quantitative aid for TS assessment. Further developments will focus on the extension of its application to everyday long‐term monitoring out of clinical environments. © 2010 Movement Disorder Society
Url:
DOI: 10.1002/mds.23188
Links toward previous steps (curation, corpus...)
- to stream Istex, to step Corpus: 000F99
- to stream Istex, to step Curation: 000F99
- to stream Istex, to step Checkpoint: 000B61
- to stream PubMed, to step Corpus: 001673
- to stream PubMed, to step Curation: 001673
- to stream PubMed, to step Checkpoint: 001A73
- to stream Ncbi, to step Merge: 002D44
- to stream Ncbi, to step Curation: 002D44
- to stream Ncbi, to step Checkpoint: 002D44
Links to Exploration step
ISTEX:7EAADFFB3158F886B533F63379B80328F29653CDLe document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">A novel automatic method for monitoring Tourette motor tics through a wearable device</title><author><name sortKey="Bernabei, Michel" sort="Bernabei, Michel" uniqKey="Bernabei M" first="Michel" last="Bernabei">Michel Bernabei</name></author><author><name sortKey="Preatoni, Ezio" sort="Preatoni, Ezio" uniqKey="Preatoni E" first="Ezio" last="Preatoni">Ezio Preatoni</name></author><author><name sortKey="Mendez, Martin" sort="Mendez, Martin" uniqKey="Mendez M" first="Martin" last="Mendez">Martin Mendez</name></author><author><name sortKey="Piccini, Luca" sort="Piccini, Luca" uniqKey="Piccini L" first="Luca" last="Piccini">Luca Piccini</name></author><author><name sortKey="Porta, Mauro" sort="Porta, Mauro" uniqKey="Porta M" first="Mauro" last="Porta">Mauro Porta</name></author><author><name sortKey="Andreoni, Giuseppe" sort="Andreoni, Giuseppe" uniqKey="Andreoni G" first="Giuseppe" last="Andreoni">Giuseppe Andreoni</name></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:7EAADFFB3158F886B533F63379B80328F29653CD</idno><date when="2010" year="2010">2010</date><idno type="doi">10.1002/mds.23188</idno><idno type="url">https://api.istex.fr/document/7EAADFFB3158F886B533F63379B80328F29653CD/fulltext/pdf</idno><idno type="wicri:Area/Istex/Corpus">000F99</idno><idno type="wicri:Area/Istex/Curation">000F99</idno><idno type="wicri:Area/Istex/Checkpoint">000B61</idno><idno type="wicri:doubleKey">0885-3185:2010:Bernabei M:a:novel:automatic</idno><idno type="wicri:source">PubMed</idno><idno type="RBID">pubmed:20669298</idno><idno type="wicri:Area/PubMed/Corpus">001673</idno><idno type="wicri:Area/PubMed/Curation">001673</idno><idno type="wicri:Area/PubMed/Checkpoint">001A73</idno><idno type="wicri:Area/Ncbi/Merge">002D44</idno><idno type="wicri:Area/Ncbi/Curation">002D44</idno><idno type="wicri:Area/Ncbi/Checkpoint">002D44</idno><idno type="wicri:Area/Main/Merge">002318</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">A novel automatic method for monitoring Tourette motor tics through a wearable device</title><author><name sortKey="Bernabei, Michel" sort="Bernabei, Michel" uniqKey="Bernabei M" first="Michel" last="Bernabei">Michel Bernabei</name><affiliation wicri:level="3"><country xml:lang="fr">Italie</country><wicri:regionArea>Dipartimento di Bioingegneria, Politecnico di Milano, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation><affiliation wicri:level="3"><country xml:lang="fr">Italie</country><wicri:regionArea>Dipartimento di Industrial Design, Arti, Comunicazione e Moda (INDACO), Politecnico di Milano, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="Preatoni, Ezio" sort="Preatoni, Ezio" uniqKey="Preatoni E" first="Ezio" last="Preatoni">Ezio Preatoni</name><affiliation wicri:level="3"><country xml:lang="fr">Italie</country><wicri:regionArea>Dipartimento di Bioingegneria, Politecnico di Milano, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation><affiliation wicri:level="3"><country xml:lang="fr">Italie</country><wicri:regionArea>Dipartimento di Industrial Design, Arti, Comunicazione e Moda (INDACO), Politecnico di Milano, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="Mendez, Martin" sort="Mendez, Martin" uniqKey="Mendez M" first="Martin" last="Mendez">Martin Mendez</name><affiliation wicri:level="3"><country xml:lang="fr">Italie</country><wicri:regionArea>Dipartimento di Bioingegneria, Politecnico di Milano, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation><affiliation wicri:level="1"><country xml:lang="fr">Mexique</country><wicri:regionArea>Facultad de Ciencias, Universidad Autónoma de San Luis Potosí, San Luis Potosí</wicri:regionArea><wicri:noRegion>San Luis Potosí</wicri:noRegion></affiliation></author><author><name sortKey="Piccini, Luca" sort="Piccini, Luca" uniqKey="Piccini L" first="Luca" last="Piccini">Luca Piccini</name><affiliation wicri:level="3"><country xml:lang="fr">Italie</country><wicri:regionArea>Dipartimento di Industrial Design, Arti, Comunicazione e Moda (INDACO), Politecnico di Milano, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="Porta, Mauro" sort="Porta, Mauro" uniqKey="Porta M" first="Mauro" last="Porta">Mauro Porta</name><affiliation wicri:level="1"><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Neurology, Tourette Centre, IRCCS “Galeazzi,” Milan</wicri:regionArea><wicri:noRegion>” Milan</wicri:noRegion></affiliation></author><author><name sortKey="Andreoni, Giuseppe" sort="Andreoni, Giuseppe" uniqKey="Andreoni G" first="Giuseppe" last="Andreoni">Giuseppe Andreoni</name><affiliation wicri:level="3"><country xml:lang="fr">Italie</country><wicri:regionArea>Dipartimento di Industrial Design, Arti, Comunicazione e Moda (INDACO), Politecnico di Milano, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author></analytic><monogr></monogr><series><title level="j">Movement Disorders</title><title level="j" type="abbrev">Mov. Disord.</title><idno type="ISSN">0885-3185</idno><idno type="eISSN">1531-8257</idno><imprint><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><pubPlace>Hoboken</pubPlace><date type="published" when="2010-09-15">2010-09-15</date><biblScope unit="vol">25</biblScope><biblScope unit="issue">12</biblScope><biblScope unit="page" from="1967">1967</biblScope><biblScope unit="page" to="1972">1972</biblScope></imprint><idno type="ISSN">0885-3185</idno></series><idno type="istex">7EAADFFB3158F886B533F63379B80328F29653CD</idno><idno type="DOI">10.1002/mds.23188</idno><idno type="ArticleID">MDS23188</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0885-3185</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adolescent</term><term>Adult</term><term>Female</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Monitoring, Ambulatory (instrumentation)</term><term>Monitoring, Ambulatory (methods)</term><term>Sensitivity and Specificity</term><term>Severity of Illness Index</term><term>Tics (diagnosis)</term><term>Tics (physiopathology)</term><term>Tourette Syndrome (diagnosis)</term><term>Tourette Syndrome (physiopathology)</term><term>Tourette syndrome</term><term>Video Recording</term><term>accelerometers</term><term>automatic tic detection</term><term>wearable monitoring</term></keywords><keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Tics</term><term>Tourette Syndrome</term></keywords><keywords scheme="MESH" qualifier="instrumentation" xml:lang="en"><term>Monitoring, Ambulatory</term></keywords><keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Monitoring, Ambulatory</term></keywords><keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Tics</term><term>Tourette Syndrome</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adolescent</term><term>Adult</term><term>Female</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Sensitivity and Specificity</term><term>Severity of Illness Index</term><term>Video Recording</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">The aim of this study was to propose a novel automatic method for quantifying motor‐tics caused by the Tourette Syndrome (TS). In this preliminary report, the feasibility of the monitoring process was tested over a series of standard clinical trials in a population of 12 subjects affected by TS. A wearable instrument with an embedded three‐axial accelerometer was used to detect and classify motor tics during standing and walking activities. An algorithm was devised to analyze acceleration data by: eliminating noise; detecting peaks connected to pathological events; and classifying intensity and frequency of motor tics into quantitative scores. These indexes were compared with the video‐based ones provided by expert clinicians, which were taken as the gold‐standard. Sensitivity, specificity, and accuracy of tic detection were estimated, and an agreement analysis was performed through the least square regression and the Bland‐Altman test. The tic recognition algorithm showed sensitivity = 80.8% ± 8.5% (mean ± SD), specificity = 75.8% ± 17.3%, and accuracy = 80.5% ± 12.2%. The agreement study showed that automatic detection tended to overestimate the number of tics occurred. Although, it appeared this may be a systematic error due to the different recognition principles of the wearable and video‐based systems. Furthermore, there was substantial concurrency with the gold‐standard in estimating the severity indexes. The proposed methodology gave promising performances in terms of automatic motor‐tics detection and classification in a standard clinical context. The system may provide physicians with a quantitative aid for TS assessment. Further developments will focus on the extension of its application to everyday long‐term monitoring out of clinical environments. © 2010 Movement Disorder Society</div></front></TEI><double doi="10.1002/mds.23188"><ISTEX><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">A novel automatic method for monitoring Tourette motor tics through a wearable device</title><author><name sortKey="Bernabei, Michel" sort="Bernabei, Michel" uniqKey="Bernabei M" first="Michel" last="Bernabei">Michel Bernabei</name></author><author><name sortKey="Preatoni, Ezio" sort="Preatoni, Ezio" uniqKey="Preatoni E" first="Ezio" last="Preatoni">Ezio Preatoni</name></author><author><name sortKey="Mendez, Martin" sort="Mendez, Martin" uniqKey="Mendez M" first="Martin" last="Mendez">Martin Mendez</name></author><author><name sortKey="Piccini, Luca" sort="Piccini, Luca" uniqKey="Piccini L" first="Luca" last="Piccini">Luca Piccini</name></author><author><name sortKey="Porta, Mauro" sort="Porta, Mauro" uniqKey="Porta M" first="Mauro" last="Porta">Mauro Porta</name></author><author><name sortKey="Andreoni, Giuseppe" sort="Andreoni, Giuseppe" uniqKey="Andreoni G" first="Giuseppe" last="Andreoni">Giuseppe Andreoni</name></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:7EAADFFB3158F886B533F63379B80328F29653CD</idno><date when="2010" year="2010">2010</date><idno type="doi">10.1002/mds.23188</idno><idno type="url">https://api.istex.fr/document/7EAADFFB3158F886B533F63379B80328F29653CD/fulltext/pdf</idno><idno type="wicri:Area/Istex/Corpus">000F99</idno><idno type="wicri:Area/Istex/Curation">000F99</idno><idno type="wicri:Area/Istex/Checkpoint">000B61</idno><idno type="wicri:doubleKey">0885-3185:2010:Bernabei M:a:novel:automatic</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">A novel automatic method for monitoring Tourette motor tics through a wearable device</title><author><name sortKey="Bernabei, Michel" sort="Bernabei, Michel" uniqKey="Bernabei M" first="Michel" last="Bernabei">Michel Bernabei</name><affiliation wicri:level="3"><country xml:lang="fr">Italie</country><wicri:regionArea>Dipartimento di Bioingegneria, Politecnico di Milano, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation><affiliation wicri:level="3"><country xml:lang="fr">Italie</country><wicri:regionArea>Dipartimento di Industrial Design, Arti, Comunicazione e Moda (INDACO), Politecnico di Milano, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="Preatoni, Ezio" sort="Preatoni, Ezio" uniqKey="Preatoni E" first="Ezio" last="Preatoni">Ezio Preatoni</name><affiliation wicri:level="3"><country xml:lang="fr">Italie</country><wicri:regionArea>Dipartimento di Bioingegneria, Politecnico di Milano, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation><affiliation wicri:level="3"><country xml:lang="fr">Italie</country><wicri:regionArea>Dipartimento di Industrial Design, Arti, Comunicazione e Moda (INDACO), Politecnico di Milano, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="Mendez, Martin" sort="Mendez, Martin" uniqKey="Mendez M" first="Martin" last="Mendez">Martin Mendez</name><affiliation wicri:level="3"><country xml:lang="fr">Italie</country><wicri:regionArea>Dipartimento di Bioingegneria, Politecnico di Milano, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation><affiliation wicri:level="1"><country xml:lang="fr">Mexique</country><wicri:regionArea>Facultad de Ciencias, Universidad Autónoma de San Luis Potosí, San Luis Potosí</wicri:regionArea><wicri:noRegion>San Luis Potosí</wicri:noRegion></affiliation></author><author><name sortKey="Piccini, Luca" sort="Piccini, Luca" uniqKey="Piccini L" first="Luca" last="Piccini">Luca Piccini</name><affiliation wicri:level="3"><country xml:lang="fr">Italie</country><wicri:regionArea>Dipartimento di Industrial Design, Arti, Comunicazione e Moda (INDACO), Politecnico di Milano, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="Porta, Mauro" sort="Porta, Mauro" uniqKey="Porta M" first="Mauro" last="Porta">Mauro Porta</name><affiliation wicri:level="1"><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Neurology, Tourette Centre, IRCCS “Galeazzi,” Milan</wicri:regionArea><wicri:noRegion>” Milan</wicri:noRegion></affiliation></author><author><name sortKey="Andreoni, Giuseppe" sort="Andreoni, Giuseppe" uniqKey="Andreoni G" first="Giuseppe" last="Andreoni">Giuseppe Andreoni</name><affiliation wicri:level="3"><country xml:lang="fr">Italie</country><wicri:regionArea>Dipartimento di Industrial Design, Arti, Comunicazione e Moda (INDACO), Politecnico di Milano, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author></analytic><monogr></monogr><series><title level="j">Movement Disorders</title><title level="j" type="abbrev">Mov. Disord.</title><idno type="ISSN">0885-3185</idno><idno type="eISSN">1531-8257</idno><imprint><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><pubPlace>Hoboken</pubPlace><date type="published" when="2010-09-15">2010-09-15</date><biblScope unit="vol">25</biblScope><biblScope unit="issue">12</biblScope><biblScope unit="page" from="1967">1967</biblScope><biblScope unit="page" to="1972">1972</biblScope></imprint><idno type="ISSN">0885-3185</idno></series><idno type="istex">7EAADFFB3158F886B533F63379B80328F29653CD</idno><idno type="DOI">10.1002/mds.23188</idno><idno type="ArticleID">MDS23188</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0885-3185</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Tourette syndrome</term><term>accelerometers</term><term>automatic tic detection</term><term>wearable monitoring</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">The aim of this study was to propose a novel automatic method for quantifying motor‐tics caused by the Tourette Syndrome (TS). In this preliminary report, the feasibility of the monitoring process was tested over a series of standard clinical trials in a population of 12 subjects affected by TS. A wearable instrument with an embedded three‐axial accelerometer was used to detect and classify motor tics during standing and walking activities. An algorithm was devised to analyze acceleration data by: eliminating noise; detecting peaks connected to pathological events; and classifying intensity and frequency of motor tics into quantitative scores. These indexes were compared with the video‐based ones provided by expert clinicians, which were taken as the gold‐standard. Sensitivity, specificity, and accuracy of tic detection were estimated, and an agreement analysis was performed through the least square regression and the Bland‐Altman test. The tic recognition algorithm showed sensitivity = 80.8% ± 8.5% (mean ± SD), specificity = 75.8% ± 17.3%, and accuracy = 80.5% ± 12.2%. The agreement study showed that automatic detection tended to overestimate the number of tics occurred. Although, it appeared this may be a systematic error due to the different recognition principles of the wearable and video‐based systems. Furthermore, there was substantial concurrency with the gold‐standard in estimating the severity indexes. The proposed methodology gave promising performances in terms of automatic motor‐tics detection and classification in a standard clinical context. The system may provide physicians with a quantitative aid for TS assessment. Further developments will focus on the extension of its application to everyday long‐term monitoring out of clinical environments. © 2010 Movement Disorder Society</div></front></TEI></ISTEX><PubMed><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">A novel automatic method for monitoring Tourette motor tics through a wearable device.</title><author><name sortKey="Bernabei, Michel" sort="Bernabei, Michel" uniqKey="Bernabei M" first="Michel" last="Bernabei">Michel Bernabei</name><affiliation wicri:level="3"><nlm:affiliation>Dipartimento di Bioingegneria, Politecnico di Milano, Milan, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Dipartimento di Bioingegneria, Politecnico di Milano, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="Preatoni, Ezio" sort="Preatoni, Ezio" uniqKey="Preatoni E" first="Ezio" last="Preatoni">Ezio Preatoni</name></author><author><name sortKey="Mendez, Martin" sort="Mendez, Martin" uniqKey="Mendez M" first="Martin" last="Mendez">Martin Mendez</name></author><author><name sortKey="Piccini, Luca" sort="Piccini, Luca" uniqKey="Piccini L" first="Luca" last="Piccini">Luca Piccini</name></author><author><name sortKey="Porta, Mauro" sort="Porta, Mauro" uniqKey="Porta M" first="Mauro" last="Porta">Mauro Porta</name></author><author><name sortKey="Andreoni, Giuseppe" sort="Andreoni, Giuseppe" uniqKey="Andreoni G" first="Giuseppe" last="Andreoni">Giuseppe Andreoni</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2010">2010</date><idno type="doi">10.1002/mds.23188</idno><idno type="RBID">pubmed:20669298</idno><idno type="pmid">20669298</idno><idno type="wicri:Area/PubMed/Corpus">001673</idno><idno type="wicri:Area/PubMed/Curation">001673</idno><idno type="wicri:Area/PubMed/Checkpoint">001A73</idno><idno type="wicri:Area/Ncbi/Merge">002D44</idno><idno type="wicri:Area/Ncbi/Curation">002D44</idno><idno type="wicri:Area/Ncbi/Checkpoint">002D44</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">A novel automatic method for monitoring Tourette motor tics through a wearable device.</title><author><name sortKey="Bernabei, Michel" sort="Bernabei, Michel" uniqKey="Bernabei M" first="Michel" last="Bernabei">Michel Bernabei</name><affiliation wicri:level="3"><nlm:affiliation>Dipartimento di Bioingegneria, Politecnico di Milano, Milan, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Dipartimento di Bioingegneria, Politecnico di Milano, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="Preatoni, Ezio" sort="Preatoni, Ezio" uniqKey="Preatoni E" first="Ezio" last="Preatoni">Ezio Preatoni</name></author><author><name sortKey="Mendez, Martin" sort="Mendez, Martin" uniqKey="Mendez M" first="Martin" last="Mendez">Martin Mendez</name></author><author><name sortKey="Piccini, Luca" sort="Piccini, Luca" uniqKey="Piccini L" first="Luca" last="Piccini">Luca Piccini</name></author><author><name sortKey="Porta, Mauro" sort="Porta, Mauro" uniqKey="Porta M" first="Mauro" last="Porta">Mauro Porta</name></author><author><name sortKey="Andreoni, Giuseppe" sort="Andreoni, Giuseppe" uniqKey="Andreoni G" first="Giuseppe" last="Andreoni">Giuseppe Andreoni</name></author></analytic><series><title level="j">Movement disorders : official journal of the Movement Disorder Society</title><idno type="eISSN">1531-8257</idno><imprint><date when="2010" type="published">2010</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adolescent</term><term>Adult</term><term>Female</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Monitoring, Ambulatory (instrumentation)</term><term>Monitoring, Ambulatory (methods)</term><term>Sensitivity and Specificity</term><term>Severity of Illness Index</term><term>Tics (diagnosis)</term><term>Tics (physiopathology)</term><term>Tourette Syndrome (diagnosis)</term><term>Tourette Syndrome (physiopathology)</term><term>Video Recording</term></keywords><keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Tics</term><term>Tourette Syndrome</term></keywords><keywords scheme="MESH" qualifier="instrumentation" xml:lang="en"><term>Monitoring, Ambulatory</term></keywords><keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Monitoring, Ambulatory</term></keywords><keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Tics</term><term>Tourette Syndrome</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adolescent</term><term>Adult</term><term>Female</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Sensitivity and Specificity</term><term>Severity of Illness Index</term><term>Video Recording</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">The aim of this study was to propose a novel automatic method for quantifying motor-tics caused by the Tourette Syndrome (TS). In this preliminary report, the feasibility of the monitoring process was tested over a series of standard clinical trials in a population of 12 subjects affected by TS. A wearable instrument with an embedded three-axial accelerometer was used to detect and classify motor tics during standing and walking activities. An algorithm was devised to analyze acceleration data by: eliminating noise; detecting peaks connected to pathological events; and classifying intensity and frequency of motor tics into quantitative scores. These indexes were compared with the video-based ones provided by expert clinicians, which were taken as the gold-standard. Sensitivity, specificity, and accuracy of tic detection were estimated, and an agreement analysis was performed through the least square regression and the Bland-Altman test. The tic recognition algorithm showed sensitivity = 80.8% ± 8.5% (mean ± SD), specificity = 75.8% ± 17.3%, and accuracy = 80.5% ± 12.2%. The agreement study showed that automatic detection tended to overestimate the number of tics occurred. Although, it appeared this may be a systematic error due to the different recognition principles of the wearable and video-based systems. Furthermore, there was substantial concurrency with the gold-standard in estimating the severity indexes. The proposed methodology gave promising performances in terms of automatic motor-tics detection and classification in a standard clinical context. The system may provide physicians with a quantitative aid for TS assessment. Further developments will focus on the extension of its application to everyday long-term monitoring out of clinical environments.</div></front></TEI></PubMed></double></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Santé/explor/MovDisordV3/Data/Main/Merge
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 002318 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Merge/biblio.hfd -nk 002318 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Santé
|area= MovDisordV3
|flux= Main
|étape= Merge
|type= RBID
|clé= ISTEX:7EAADFFB3158F886B533F63379B80328F29653CD
|texte= A novel automatic method for monitoring Tourette motor tics through a wearable device
}}
| This area was generated with Dilib version V0.6.23. |  |