Visual hallucinations and altered visual information processing in Parkinson disease and dementia with Lewy bodies
Identifieur interne : 001D51 ( Main/Merge ); précédent : 001D50; suivant : 001D52Visual hallucinations and altered visual information processing in Parkinson disease and dementia with Lewy bodies
Auteurs : Akira Kurita [Japon] ; Maiko Murakami [Japon] ; Satoshi Takagi [Japon] ; Masato Matsushima [Japon] ; Masahiko Suzuki [Japon]Source :
- Movement Disorders [ 0885-3185 ] ; 2010-01-30.
English descriptors
- KwdEn :
- Aged, Aged, 80 and over, Alzheimer Disease (physiopathology), Alzheimer Disease (psychology), Auditory Perception, Brain (physiopathology), Brain Mapping, Cognition, Dementia (diagnosis), Dementia (physiopathology), Dementia (psychology), Discrimination (Psychology), Electroencephalography, Evoked Potentials, Female, Hallucinations (physiopathology), Hallucinations (psychology), Humans, Lewy Body Disease (physiopathology), Lewy Body Disease (psychology), Male, Middle Aged, Neuropsychological Tests, Parkinson Disease (physiopathology), Parkinson Disease (psychology), Parkinson's disease, Psychiatric Status Rating Scales, Psychomotor Performance, Reaction Time, Visual Perception, dementia with Lewy bodies, event‐related potentials, information processing, visual hallucinations.
- MESH :
- diagnosis : Dementia.
- physiopathology : Alzheimer Disease, Brain, Dementia, Hallucinations, Lewy Body Disease, Parkinson Disease.
- psychology : Alzheimer Disease, Dementia, Hallucinations, Lewy Body Disease, Parkinson Disease.
- Aged, Aged, 80 and over, Auditory Perception, Brain Mapping, Cognition, Discrimination (Psychology), Electroencephalography, Evoked Potentials, Female, Humans, Male, Middle Aged, Neuropsychological Tests, Psychiatric Status Rating Scales, Psychomotor Performance, Reaction Time, Visual Perception.
Abstract
Visual hallucinations (VHs) are common in dementia with Lewy bodies (DLB) and Parkinson's disease with dementia (PDD), while auditory hallucinations are rare. To neurophysiologically investigate the pathophysiology of VHs in these disorders, we studied event‐related potentials (ERPs) of DLB, PDD, and Alzheimer's disease (AD) patients. We compared visual and auditory ERP latencies among PDD patients with and without VHs (PDD‐H: 11, PDD‐N: 6), DLB patients (24), and AD patients (21). To elicit visual and auditory ERPs, a facial discrimination paradigm and a conventional auditory odd‐ball paradigm, respectively, were used. The mean visual P3 latencies in the PDD‐H and DLB groups were significantly longer than that in the AD group, while the mean auditory P3 latencies in all four patient groups were comparable. The mean visual P2 latencies in the PDD‐N, PDD‐H, and DLB groups were significantly longer than that in the control group. Our findings suggest that visual cognitive functions are selectively impaired in hallucinatory patients with DLB and PDD. VHs may be associated in part with predominant visual cognitive impairments attributable to PDD and DLB pathologies. Our findings also suggest that the impairments occur at the early stage of facial information processing. © 2010 Movement Disorder Society
Url:
DOI: 10.1002/mds.22919
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Disord.</title><idno type="ISSN">0885-3185</idno><idno type="eISSN">1531-8257</idno><imprint><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><pubPlace>Hoboken</pubPlace><date type="published" when="2010-01-30">2010-01-30</date><biblScope unit="vol">25</biblScope><biblScope unit="issue">2</biblScope><biblScope unit="page" from="167">167</biblScope><biblScope unit="page" to="171">171</biblScope></imprint><idno type="ISSN">0885-3185</idno></series><idno type="istex">6B2FE442E197690874AEB929627976162552F55F</idno><idno type="DOI">10.1002/mds.22919</idno><idno type="ArticleID">MDS22919</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0885-3185</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Aged</term><term>Aged, 80 and over</term><term>Alzheimer Disease (physiopathology)</term><term>Alzheimer Disease (psychology)</term><term>Auditory Perception</term><term>Brain (physiopathology)</term><term>Brain Mapping</term><term>Cognition</term><term>Dementia (diagnosis)</term><term>Dementia (physiopathology)</term><term>Dementia (psychology)</term><term>Discrimination (Psychology)</term><term>Electroencephalography</term><term>Evoked Potentials</term><term>Female</term><term>Hallucinations (physiopathology)</term><term>Hallucinations (psychology)</term><term>Humans</term><term>Lewy Body Disease (physiopathology)</term><term>Lewy Body Disease (psychology)</term><term>Male</term><term>Middle Aged</term><term>Neuropsychological Tests</term><term>Parkinson Disease (physiopathology)</term><term>Parkinson Disease (psychology)</term><term>Parkinson's disease</term><term>Psychiatric Status Rating Scales</term><term>Psychomotor Performance</term><term>Reaction Time</term><term>Visual Perception</term><term>dementia with Lewy bodies</term><term>event‐related potentials</term><term>information processing</term><term>visual hallucinations</term></keywords><keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Dementia</term></keywords><keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Alzheimer Disease</term><term>Brain</term><term>Dementia</term><term>Hallucinations</term><term>Lewy Body Disease</term><term>Parkinson Disease</term></keywords><keywords scheme="MESH" qualifier="psychology" xml:lang="en"><term>Alzheimer Disease</term><term>Dementia</term><term>Hallucinations</term><term>Lewy Body Disease</term><term>Parkinson Disease</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Aged</term><term>Aged, 80 and over</term><term>Auditory Perception</term><term>Brain Mapping</term><term>Cognition</term><term>Discrimination (Psychology)</term><term>Electroencephalography</term><term>Evoked Potentials</term><term>Female</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Neuropsychological Tests</term><term>Psychiatric Status Rating Scales</term><term>Psychomotor Performance</term><term>Reaction Time</term><term>Visual Perception</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Visual hallucinations (VHs) are common in dementia with Lewy bodies (DLB) and Parkinson's disease with dementia (PDD), while auditory hallucinations are rare. To neurophysiologically investigate the pathophysiology of VHs in these disorders, we studied event‐related potentials (ERPs) of DLB, PDD, and Alzheimer's disease (AD) patients. We compared visual and auditory ERP latencies among PDD patients with and without VHs (PDD‐H: 11, PDD‐N: 6), DLB patients (24), and AD patients (21). To elicit visual and auditory ERPs, a facial discrimination paradigm and a conventional auditory odd‐ball paradigm, respectively, were used. The mean visual P3 latencies in the PDD‐H and DLB groups were significantly longer than that in the AD group, while the mean auditory P3 latencies in all four patient groups were comparable. The mean visual P2 latencies in the PDD‐N, PDD‐H, and DLB groups were significantly longer than that in the control group. Our findings suggest that visual cognitive functions are selectively impaired in hallucinatory patients with DLB and PDD. VHs may be associated in part with predominant visual cognitive impairments attributable to PDD and DLB pathologies. Our findings also suggest that the impairments occur at the early stage of facial information processing. © 2010 Movement Disorder Society</div></front></TEI><double doi="10.1002/mds.22919"><ISTEX><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Visual hallucinations and altered visual information processing in Parkinson disease and dementia with Lewy bodies</title><author><name sortKey="Kurita, Akira" sort="Kurita, Akira" uniqKey="Kurita A" first="Akira" last="Kurita">Akira Kurita</name></author><author><name sortKey="Murakami, Maiko" sort="Murakami, Maiko" uniqKey="Murakami M" first="Maiko" last="Murakami">Maiko Murakami</name></author><author><name sortKey="Takagi, Satoshi" sort="Takagi, Satoshi" uniqKey="Takagi S" first="Satoshi" last="Takagi">Satoshi Takagi</name></author><author><name sortKey="Matsushima, Masato" sort="Matsushima, Masato" uniqKey="Matsushima M" first="Masato" last="Matsushima">Masato Matsushima</name></author><author><name sortKey="Suzuki, Masahiko" sort="Suzuki, Masahiko" uniqKey="Suzuki M" first="Masahiko" last="Suzuki">Masahiko Suzuki</name></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:6B2FE442E197690874AEB929627976162552F55F</idno><date when="2010" year="2010">2010</date><idno type="doi">10.1002/mds.22919</idno><idno type="url">https://api.istex.fr/document/6B2FE442E197690874AEB929627976162552F55F/fulltext/pdf</idno><idno type="wicri:Area/Istex/Corpus">002121</idno><idno type="wicri:Area/Istex/Curation">002121</idno><idno type="wicri:Area/Istex/Checkpoint">000594</idno><idno type="wicri:doubleKey">0885-3185:2010:Kurita A:visual:hallucinations:and</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Visual hallucinations and altered visual information processing in Parkinson disease and dementia with Lewy bodies</title><author><name sortKey="Kurita, Akira" sort="Kurita, Akira" uniqKey="Kurita A" first="Akira" last="Kurita">Akira Kurita</name><affiliation wicri:level="3"><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Neurology, Jikei University School of Medicine, Tokyo</wicri:regionArea><placeName><settlement type="city">Tokyo</settlement></placeName></affiliation></author><author><name sortKey="Murakami, Maiko" sort="Murakami, Maiko" uniqKey="Murakami M" first="Maiko" last="Murakami">Maiko Murakami</name><affiliation wicri:level="3"><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Neurology, Jikei University School of Medicine, Tokyo</wicri:regionArea><placeName><settlement type="city">Tokyo</settlement></placeName></affiliation></author><author><name sortKey="Takagi, Satoshi" sort="Takagi, Satoshi" uniqKey="Takagi S" first="Satoshi" last="Takagi">Satoshi Takagi</name><affiliation wicri:level="3"><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Neurology, Jikei University School of Medicine, Tokyo</wicri:regionArea><placeName><settlement type="city">Tokyo</settlement></placeName></affiliation></author><author><name sortKey="Matsushima, Masato" sort="Matsushima, Masato" uniqKey="Matsushima M" first="Masato" last="Matsushima">Masato Matsushima</name><affiliation wicri:level="3"><country xml:lang="fr">Japon</country><wicri:regionArea>Division of Clinical Epidemiology, Jikei University School of Medicine, Tokyo</wicri:regionArea><placeName><settlement type="city">Tokyo</settlement></placeName></affiliation></author><author><name sortKey="Suzuki, Masahiko" sort="Suzuki, Masahiko" uniqKey="Suzuki M" first="Masahiko" last="Suzuki">Masahiko Suzuki</name><affiliation wicri:level="3"><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Neurology, Jikei University School of Medicine, Tokyo</wicri:regionArea><placeName><settlement type="city">Tokyo</settlement></placeName></affiliation></author></analytic><monogr></monogr><series><title level="j">Movement Disorders</title><title level="j" type="abbrev">Mov. Disord.</title><idno type="ISSN">0885-3185</idno><idno type="eISSN">1531-8257</idno><imprint><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><pubPlace>Hoboken</pubPlace><date type="published" when="2010-01-30">2010-01-30</date><biblScope unit="vol">25</biblScope><biblScope unit="issue">2</biblScope><biblScope unit="page" from="167">167</biblScope><biblScope unit="page" to="171">171</biblScope></imprint><idno type="ISSN">0885-3185</idno></series><idno type="istex">6B2FE442E197690874AEB929627976162552F55F</idno><idno type="DOI">10.1002/mds.22919</idno><idno type="ArticleID">MDS22919</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0885-3185</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Parkinson's disease</term><term>dementia with Lewy bodies</term><term>event‐related potentials</term><term>information processing</term><term>visual hallucinations</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Visual hallucinations (VHs) are common in dementia with Lewy bodies (DLB) and Parkinson's disease with dementia (PDD), while auditory hallucinations are rare. To neurophysiologically investigate the pathophysiology of VHs in these disorders, we studied event‐related potentials (ERPs) of DLB, PDD, and Alzheimer's disease (AD) patients. We compared visual and auditory ERP latencies among PDD patients with and without VHs (PDD‐H: 11, PDD‐N: 6), DLB patients (24), and AD patients (21). To elicit visual and auditory ERPs, a facial discrimination paradigm and a conventional auditory odd‐ball paradigm, respectively, were used. The mean visual P3 latencies in the PDD‐H and DLB groups were significantly longer than that in the AD group, while the mean auditory P3 latencies in all four patient groups were comparable. The mean visual P2 latencies in the PDD‐N, PDD‐H, and DLB groups were significantly longer than that in the control group. Our findings suggest that visual cognitive functions are selectively impaired in hallucinatory patients with DLB and PDD. VHs may be associated in part with predominant visual cognitive impairments attributable to PDD and DLB pathologies. Our findings also suggest that the impairments occur at the early stage of facial information processing. © 2010 Movement Disorder Society</div></front></TEI></ISTEX><PubMed><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Visual hallucinations and altered visual information processing in Parkinson disease and dementia with Lewy bodies.</title><author><name sortKey="Kurita, Akira" sort="Kurita, Akira" uniqKey="Kurita A" first="Akira" last="Kurita">Akira Kurita</name><affiliation wicri:level="3"><nlm:affiliation>Department of Neurology, Jikei University School of Medicine, Kashiwa Hospital, Tokyo, Japan. a-kurita@jikei.ac.jp</nlm:affiliation><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Neurology, Jikei University School of Medicine, Kashiwa Hospital, Tokyo</wicri:regionArea><placeName><settlement type="city">Tokyo</settlement></placeName></affiliation></author><author><name sortKey="Murakami, Maiko" sort="Murakami, Maiko" uniqKey="Murakami M" first="Maiko" last="Murakami">Maiko Murakami</name></author><author><name sortKey="Takagi, Satoshi" sort="Takagi, Satoshi" uniqKey="Takagi S" first="Satoshi" last="Takagi">Satoshi Takagi</name></author><author><name sortKey="Matsushima, Masato" sort="Matsushima, Masato" uniqKey="Matsushima M" first="Masato" last="Matsushima">Masato Matsushima</name></author><author><name sortKey="Suzuki, Masahiko" sort="Suzuki, Masahiko" uniqKey="Suzuki M" first="Masahiko" last="Suzuki">Masahiko Suzuki</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2010">2010</date><idno type="doi">10.1002/mds.22919</idno><idno type="RBID">pubmed:20063433</idno><idno type="pmid">20063433</idno><idno type="wicri:Area/PubMed/Corpus">001A32</idno><idno type="wicri:Area/PubMed/Curation">001A32</idno><idno type="wicri:Area/PubMed/Checkpoint">001522</idno><idno type="wicri:Area/Ncbi/Merge">002970</idno><idno type="wicri:Area/Ncbi/Curation">002970</idno><idno type="wicri:Area/Ncbi/Checkpoint">002970</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Visual hallucinations and altered visual information processing in Parkinson disease and dementia with Lewy bodies.</title><author><name sortKey="Kurita, Akira" sort="Kurita, Akira" uniqKey="Kurita A" first="Akira" last="Kurita">Akira Kurita</name><affiliation wicri:level="3"><nlm:affiliation>Department of Neurology, Jikei University School of Medicine, Kashiwa Hospital, Tokyo, Japan. a-kurita@jikei.ac.jp</nlm:affiliation><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Neurology, Jikei University School of Medicine, Kashiwa Hospital, Tokyo</wicri:regionArea><placeName><settlement type="city">Tokyo</settlement></placeName></affiliation></author><author><name sortKey="Murakami, Maiko" sort="Murakami, Maiko" uniqKey="Murakami M" first="Maiko" last="Murakami">Maiko Murakami</name></author><author><name sortKey="Takagi, Satoshi" sort="Takagi, Satoshi" uniqKey="Takagi S" first="Satoshi" last="Takagi">Satoshi Takagi</name></author><author><name sortKey="Matsushima, Masato" sort="Matsushima, Masato" uniqKey="Matsushima M" first="Masato" last="Matsushima">Masato Matsushima</name></author><author><name sortKey="Suzuki, Masahiko" sort="Suzuki, Masahiko" uniqKey="Suzuki M" first="Masahiko" last="Suzuki">Masahiko Suzuki</name></author></analytic><series><title level="j">Movement disorders : official journal of the Movement Disorder Society</title><idno type="eISSN">1531-8257</idno><imprint><date when="2010" type="published">2010</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Aged</term><term>Aged, 80 and over</term><term>Alzheimer Disease (physiopathology)</term><term>Alzheimer Disease (psychology)</term><term>Auditory Perception</term><term>Brain (physiopathology)</term><term>Brain Mapping</term><term>Cognition</term><term>Dementia (diagnosis)</term><term>Dementia (physiopathology)</term><term>Dementia (psychology)</term><term>Discrimination (Psychology)</term><term>Electroencephalography</term><term>Evoked Potentials</term><term>Female</term><term>Hallucinations (physiopathology)</term><term>Hallucinations (psychology)</term><term>Humans</term><term>Lewy Body Disease (physiopathology)</term><term>Lewy Body Disease (psychology)</term><term>Male</term><term>Middle Aged</term><term>Neuropsychological Tests</term><term>Parkinson Disease (physiopathology)</term><term>Parkinson Disease (psychology)</term><term>Psychiatric Status Rating Scales</term><term>Psychomotor Performance</term><term>Reaction Time</term><term>Visual Perception</term></keywords><keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Dementia</term></keywords><keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Alzheimer Disease</term><term>Brain</term><term>Dementia</term><term>Hallucinations</term><term>Lewy Body Disease</term><term>Parkinson Disease</term></keywords><keywords scheme="MESH" qualifier="psychology" xml:lang="en"><term>Alzheimer Disease</term><term>Dementia</term><term>Hallucinations</term><term>Lewy Body Disease</term><term>Parkinson Disease</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Aged</term><term>Aged, 80 and over</term><term>Auditory Perception</term><term>Brain Mapping</term><term>Cognition</term><term>Discrimination (Psychology)</term><term>Electroencephalography</term><term>Evoked Potentials</term><term>Female</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Neuropsychological Tests</term><term>Psychiatric Status Rating Scales</term><term>Psychomotor Performance</term><term>Reaction Time</term><term>Visual Perception</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Visual hallucinations (VHs) are common in dementia with Lewy bodies (DLB) and Parkinson's disease with dementia (PDD), while auditory hallucinations are rare. To neurophysiologically investigate the pathophysiology of VHs in these disorders, we studied event-related potentials (ERPs) of DLB, PDD, and Alzheimer's disease (AD) patients. We compared visual and auditory ERP latencies among PDD patients with and without VHs (PDD-H: 11, PDD-N: 6), DLB patients (24), and AD patients (21). To elicit visual and auditory ERPs, a facial discrimination paradigm and a conventional auditory odd-ball paradigm, respectively, were used. The mean visual P3 latencies in the PDD-H and DLB groups were significantly longer than that in the AD group, while the mean auditory P3 latencies in all four patient groups were comparable. The mean visual P2 latencies in the PDD-N, PDD-H, and DLB groups were significantly longer than that in the control group. Our findings suggest that visual cognitive functions are selectively impaired in hallucinatory patients with DLB and PDD. VHs may be associated in part with predominant visual cognitive impairments attributable to PDD and DLB pathologies. Our findings also suggest that the impairments occur at the early stage of facial information processing.</div></front></TEI></PubMed></double></record>Pour manipuler ce document sous Unix (Dilib)
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