Lewy Pathology and Neurodegeneration in Premotor Parkinson's Disease
Identifieur interne : 001125 ( Main/Merge ); précédent : 001124; suivant : 001126Lewy Pathology and Neurodegeneration in Premotor Parkinson's Disease
Auteurs : Kelly Del Tredici [Allemagne] ; Heiko Braak [Allemagne]Source :
- Movement disorders [ 0885-3185 ] ; 2012.
Descripteurs français
- Pascal (Inist)
English descriptors
- KwdEn :
Abstract
The foremost motor manifestations of Parkinson's disease are resting tremor, cogwheel rigidity, hypokinesia/bradykinesia, and postural instability. Epidemiological and clinical data reveal that a wide variety of additional complaints (nonmotor symptoms), also considerably impar patients' quality of life parallel to the chronic-progressive neurodegenerative disorder. This article reviews the neuropathology and anatomy of Lewy pathology-related neurodegeneration in relation to selected nonmotro and prodromal dysfunctions.
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Pascal:12-0223364Le document en format XML
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<term>Lewy body disease</term>
<term>Nervous system</term>
<term>Nervous system diseases</term>
<term>Neurite</term>
<term>Neuron</term>
<term>Parkinson disease</term>
<term>Spinal cord</term>
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<term>Système nerveux autonome</term>
<term>Système nerveux</term>
<term>Neurone</term>
<term>Corps Lewy</term>
<term>Neurite</term>
<term>Sporadique</term>
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<front><div type="abstract" xml:lang="en">The foremost motor manifestations of Parkinson's disease are resting tremor, cogwheel rigidity, hypokinesia/bradykinesia, and postural instability. Epidemiological and clinical data reveal that a wide variety of additional complaints (nonmotor symptoms), also considerably impar patients' quality of life parallel to the chronic-progressive neurodegenerative disorder. This article reviews the neuropathology and anatomy of Lewy pathology-related neurodegeneration in relation to selected nonmotro and prodromal dysfunctions.</div>
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