Lewy Pathology and Neurodegeneration in Premotor Parkinson's Disease
Identifieur interne : 000146 ( PascalFrancis/Checkpoint ); précédent : 000145; suivant : 000147Lewy Pathology and Neurodegeneration in Premotor Parkinson's Disease
Auteurs : Kelly Del Tredici [Allemagne] ; Heiko Braak [Allemagne]Source :
- Movement disorders [ 0885-3185 ] ; 2012.
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- Pascal (Inist)
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Abstract
The foremost motor manifestations of Parkinson's disease are resting tremor, cogwheel rigidity, hypokinesia/bradykinesia, and postural instability. Epidemiological and clinical data reveal that a wide variety of additional complaints (nonmotor symptoms), also considerably impar patients' quality of life parallel to the chronic-progressive neurodegenerative disorder. This article reviews the neuropathology and anatomy of Lewy pathology-related neurodegeneration in relation to selected nonmotro and prodromal dysfunctions.
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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en" level="a">Lewy Pathology and Neurodegeneration in Premotor Parkinson's Disease</title><author><name sortKey="Del Tredici, Kelly" sort="Del Tredici, Kelly" uniqKey="Del Tredici K" first="Kelly" last="Del Tredici">Kelly Del Tredici</name><affiliation wicri:level="4"><inist:fA14 i1="01"><s1>Clinical Neuroanatomy Section, Department of Neurology, Center for Biomedical Research, University of Ulm</s1><s2>Ulm</s2><s3>DEU</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ></inist:fA14><country>Allemagne</country><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Tübingen</region><settlement type="city">Ulm</settlement></placeName><orgName type="university">Université d'Ulm</orgName></affiliation></author><author><name sortKey="Braak, Heiko" sort="Braak, Heiko" uniqKey="Braak H" first="Heiko" last="Braak">Heiko Braak</name><affiliation wicri:level="4"><inist:fA14 i1="01"><s1>Clinical Neuroanatomy Section, Department of Neurology, Center for Biomedical Research, University of Ulm</s1><s2>Ulm</s2><s3>DEU</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ></inist:fA14><country>Allemagne</country><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Tübingen</region><settlement type="city">Ulm</settlement></placeName><orgName type="university">Université d'Ulm</orgName></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">INIST</idno><idno type="inist">12-0223364</idno><date when="2012">2012</date><idno type="stanalyst">PASCAL 12-0223364 INIST</idno><idno type="RBID">Pascal:12-0223364</idno><idno type="wicri:Area/PascalFrancis/Corpus">000203</idno><idno type="wicri:Area/PascalFrancis/Curation">002B11</idno><idno type="wicri:Area/PascalFrancis/Checkpoint">000146</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a">Lewy Pathology and Neurodegeneration in Premotor Parkinson's Disease</title><author><name sortKey="Del Tredici, Kelly" sort="Del Tredici, Kelly" uniqKey="Del Tredici K" first="Kelly" last="Del Tredici">Kelly Del Tredici</name><affiliation wicri:level="4"><inist:fA14 i1="01"><s1>Clinical Neuroanatomy Section, Department of Neurology, Center for Biomedical Research, University of Ulm</s1><s2>Ulm</s2><s3>DEU</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ></inist:fA14><country>Allemagne</country><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Tübingen</region><settlement type="city">Ulm</settlement></placeName><orgName type="university">Université d'Ulm</orgName></affiliation></author><author><name sortKey="Braak, Heiko" sort="Braak, Heiko" uniqKey="Braak H" first="Heiko" last="Braak">Heiko Braak</name><affiliation wicri:level="4"><inist:fA14 i1="01"><s1>Clinical Neuroanatomy Section, Department of Neurology, Center for Biomedical Research, University of Ulm</s1><s2>Ulm</s2><s3>DEU</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ></inist:fA14><country>Allemagne</country><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Tübingen</region><settlement type="city">Ulm</settlement></placeName><orgName type="university">Université d'Ulm</orgName></affiliation></author></analytic><series><title level="j" type="main">Movement disorders</title><title level="j" type="abbreviated">Mov. disord.</title><idno type="ISSN">0885-3185</idno><imprint><date when="2012">2012</date></imprint></series></biblStruct></sourceDesc><seriesStmt><title level="j" type="main">Movement disorders</title><title level="j" type="abbreviated">Mov. disord.</title><idno type="ISSN">0885-3185</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Anatomic pathology</term><term>Autonomic nervous system</term><term>Lewy body</term><term>Lewy body dementia</term><term>Lewy body disease</term><term>Nervous system</term><term>Nervous system diseases</term><term>Neurite</term><term>Neuron</term><term>Parkinson disease</term><term>Spinal cord</term><term>Sporadic</term><term>Superior cervical ganglion</term></keywords><keywords scheme="Pascal" xml:lang="fr"><term>Maladie de Parkinson</term><term>Démence à corps de Lewy</term><term>Pathologie du système nerveux</term><term>Anatomopathologie</term><term>Système nerveux autonome</term><term>Système nerveux</term><term>Neurone</term><term>Corps Lewy</term><term>Neurite</term><term>Sporadique</term><term>Moelle épinière</term><term>Ganglion cervical supérieur</term><term>Corps Lewy maladie</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">The foremost motor manifestations of Parkinson's disease are resting tremor, cogwheel rigidity, hypokinesia/bradykinesia, and postural instability. Epidemiological and clinical data reveal that a wide variety of additional complaints (nonmotor symptoms), also considerably impar patients' quality of life parallel to the chronic-progressive neurodegenerative disorder. This article reviews the neuropathology and anatomy of Lewy pathology-related neurodegeneration in relation to selected nonmotro and prodromal dysfunctions.</div></front></TEI><inist><standard h6="B"><pA><fA01 i1="01" i2="1"><s0>0885-3185</s0></fA01><fA03 i2="1"><s0>Mov. disord.</s0></fA03><fA05><s2>27</s2></fA05><fA06><s2>5</s2></fA06><fA08 i1="01" i2="1" l="ENG"><s1>Lewy Pathology and Neurodegeneration in Premotor Parkinson's Disease</s1></fA08><fA09 i1="01" i2="1" l="ENG"><s1>Prodromal Parkinson's Disease</s1></fA09><fA11 i1="01" i2="1"><s1>DEL TREDICI (Kelly)</s1></fA11><fA11 i1="02" i2="1"><s1>BRAAK (Heiko)</s1></fA11><fA12 i1="01" i2="1"><s1>BERG (Daniela)</s1><s9>ed.</s9></fA12><fA12 i1="02" i2="1"><s1>POEWE (Werner)</s1><s9>ed.</s9></fA12><fA14 i1="01"><s1>Clinical Neuroanatomy Section, Department of Neurology, Center for Biomedical Research, University of Ulm</s1><s2>Ulm</s2><s3>DEU</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ></fA14><fA15 i1="01"><s1>Department of Neurodegeneration, Hertie Institute of Clinical Brain Research and German Center of Neurodegenerative Diseases (DZNE), University of Tübingen</s1><s2>Tübingen</s2><s3>DEU</s3><sZ>1 aut.</sZ></fA15><fA15 i1="02"><s1>Department of Neurology, University of Innsbruck</s1><s2>Innsbruck</s2><s3>AUT</s3><sZ>2 aut.</sZ></fA15><fA20><s1>597-607</s1></fA20><fA21><s1>2012</s1></fA21><fA23 i1="01"><s0>ENG</s0></fA23><fA43 i1="01"><s1>INIST</s1><s2>20953</s2><s5>354000506918320010</s5></fA43><fA44><s0>0000</s0><s1>© 2012 INIST-CNRS. 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sortKey="Del Tredici, Kelly" sort="Del Tredici, Kelly" uniqKey="Del Tredici K" first="Kelly" last="Del Tredici">Kelly Del Tredici</name></region><name sortKey="Braak, Heiko" sort="Braak, Heiko" uniqKey="Braak H" first="Heiko" last="Braak">Heiko Braak</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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