The Association between Mediterranean Diet Adherence and Parkinson’s Disease
Identifieur interne : 000B93 ( Main/Merge ); précédent : 000B92; suivant : 000B94The Association between Mediterranean Diet Adherence and Parkinson’s Disease
Auteurs : Rn Alcalay [États-Unis] ; Y. Gu [États-Unis] ; H. Mejia-Santana [États-Unis] ; L. Cote [États-Unis] ; Ks Marder [États-Unis] ; N. Scarmeas [États-Unis]Source :
- Movement Disorders [ 0885-3185 ] ; 2012.
English descriptors
- KwdEn :
- MESH :
- etiology : Parkinson Disease.
- statistics & numerical data : Patient Compliance.
- Aged, Aged, 80 and over, Body Mass Index, Case-Control Studies, Diet, Mediterranean, Energy Intake, Female, Humans, Male, Middle Aged, Questionnaires, Risk, Risk Factors.
Abstract
Recent studies demonstrated an association between a Mediterranean-type diet and Alzheimer’s risk. We assessed the association between Mediterranean-type diet adherence and PD status.
257 PD participants and 198 controls completed the Willett semi-quantitative questionnaire that quantifies diet during the past year. Scores were calculated using a 9-point scale; higher scores indicated greater adherence to the Mediterranean-type diet. Logistic regression models were used to assess the association between PD status and Mediterranean-type diet, adjusting for caloric intake, age, gender, education and ethnicity. Adjusted linear regression models were used to examine the association between Mediterranean-type diet adherence and PD age-at-onset.
Higher Mediterranean-type diet adherence was associated with reduced odds for PD after adjustment for all covariates (OR=0.86, 95%CI=0.77–0.97, p=0.010). Lower Mediterranean-type diet score was associated with earlier PD age-at-onset (β=1.09, p=0.010).
PD patients adhere less than controls to the Mediterranean-type diet. Dietary behavior may be associated with age-at-onset.
Url:
DOI: 10.1002/mds.24918
PubMed: 22314772
PubMed Central: 3349773
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PMC:3349773Le document en format XML
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<series><title level="j">Movement Disorders</title>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Aged</term>
<term>Aged, 80 and over</term>
<term>Body Mass Index</term>
<term>Case-Control Studies</term>
<term>Diet, Mediterranean</term>
<term>Energy Intake</term>
<term>Female</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Parkinson Disease (etiology)</term>
<term>Patient Compliance (statistics & numerical data)</term>
<term>Questionnaires</term>
<term>Risk</term>
<term>Risk Factors</term>
</keywords>
<keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Parkinson Disease</term>
</keywords>
<keywords scheme="MESH" qualifier="statistics & numerical data" xml:lang="en"><term>Patient Compliance</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Aged</term>
<term>Aged, 80 and over</term>
<term>Body Mass Index</term>
<term>Case-Control Studies</term>
<term>Diet, Mediterranean</term>
<term>Energy Intake</term>
<term>Female</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Questionnaires</term>
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<front><div type="abstract" xml:lang="en"><sec id="S1"><title>Objective</title>
<p id="P1">Recent studies demonstrated an association between a Mediterranean-type diet and Alzheimer’s risk. We assessed the association between Mediterranean-type diet adherence and PD status.</p>
</sec>
<sec id="S2"><title>Methods</title>
<p id="P2">257 PD participants and 198 controls completed the Willett semi-quantitative questionnaire that quantifies diet during the past year. Scores were calculated using a 9-point scale; higher scores indicated greater adherence to the Mediterranean-type diet. Logistic regression models were used to assess the association between PD status and Mediterranean-type diet, adjusting for caloric intake, age, gender, education and ethnicity. Adjusted linear regression models were used to examine the association between Mediterranean-type diet adherence and PD age-at-onset.</p>
</sec>
<sec id="S3"><title>Results</title>
<p id="P3">Higher Mediterranean-type diet adherence was associated with reduced odds for PD after adjustment for all covariates (OR=0.86, 95%CI=0.77–0.97, p=0.010). Lower Mediterranean-type diet score was associated with earlier PD age-at-onset (β=1.09, p=0.010).</p>
</sec>
<sec id="S4"><title>Conclusions</title>
<p id="P4">PD patients adhere less than controls to the Mediterranean-type diet. Dietary behavior may be associated with age-at-onset.</p>
</sec>
</div>
</front>
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