Onset latency of segmental dystonia after deep brain stimulation cessation: a randomized, double-blind crossover trial.
Identifieur interne : 000491 ( Main/Merge ); précédent : 000490; suivant : 000492Onset latency of segmental dystonia after deep brain stimulation cessation: a randomized, double-blind crossover trial.
Auteurs : Johannes Levin [Allemagne] ; Arun Singh ; Berend Feddersen ; Jan-Hinnerk Mehrkens ; Kai BötzelSource :
- Movement disorders : official journal of the Movement Disorder Society [ 1531-8257 ] ; 2014.
English descriptors
- KwdEn :
- MESH :
- adverse effects : Deep Brain Stimulation.
- etiology : Dystonia.
- physiology : Globus Pallidus.
- physiopathology : Dystonia.
- Cross-Over Studies, Double-Blind Method, Electrodes, Implanted, Humans, Treatment Outcome.
Abstract
Deep brain stimulation (DBS) of the globus pallidus internus is an effective treatment for cervical dystonia (CD). Interestingly, the onset of initial DBS effects is significantly prolonged compared with that in other diseases, such as Parkinson's disease. The return of symptoms after cessation of DBS could be delayed as well, but this has not been studied systematically.
DOI: 10.1002/mds.25780
PubMed: 24375720
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pubmed:24375720Le document en format XML
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<country xml:lang="fr">Allemagne</country>
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<author><name sortKey="Singh, Arun" sort="Singh, Arun" uniqKey="Singh A" first="Arun" last="Singh">Arun Singh</name>
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<author><name sortKey="Feddersen, Berend" sort="Feddersen, Berend" uniqKey="Feddersen B" first="Berend" last="Feddersen">Berend Feddersen</name>
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<author><name sortKey="Mehrkens, Jan Hinnerk" sort="Mehrkens, Jan Hinnerk" uniqKey="Mehrkens J" first="Jan-Hinnerk" last="Mehrkens">Jan-Hinnerk Mehrkens</name>
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<term>Dystonia (physiopathology)</term>
<term>Electrodes, Implanted</term>
<term>Globus Pallidus (physiology)</term>
<term>Humans</term>
<term>Treatment Outcome</term>
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<front><div type="abstract" xml:lang="en">Deep brain stimulation (DBS) of the globus pallidus internus is an effective treatment for cervical dystonia (CD). Interestingly, the onset of initial DBS effects is significantly prolonged compared with that in other diseases, such as Parkinson's disease. The return of symptoms after cessation of DBS could be delayed as well, but this has not been studied systematically.</div>
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