Onset latency of segmental dystonia after deep brain stimulation cessation: a randomized, double-blind crossover trial.
Identifieur interne : 000630 ( PubMed/Corpus ); précédent : 000629; suivant : 000631Onset latency of segmental dystonia after deep brain stimulation cessation: a randomized, double-blind crossover trial.
Auteurs : Johannes Levin ; Arun Singh ; Berend Feddersen ; Jan-Hinnerk Mehrkens ; Kai BötzelSource :
- Movement disorders : official journal of the Movement Disorder Society [ 1531-8257 ] ; 2014.
English descriptors
- KwdEn :
- MESH :
- adverse effects : Deep Brain Stimulation.
- etiology : Dystonia.
- physiology : Globus Pallidus.
- physiopathology : Dystonia.
- Cross-Over Studies, Double-Blind Method, Electrodes, Implanted, Humans, Treatment Outcome.
Abstract
Deep brain stimulation (DBS) of the globus pallidus internus is an effective treatment for cervical dystonia (CD). Interestingly, the onset of initial DBS effects is significantly prolonged compared with that in other diseases, such as Parkinson's disease. The return of symptoms after cessation of DBS could be delayed as well, but this has not been studied systematically.
DOI: 10.1002/mds.25780
PubMed: 24375720
Links to Exploration step
pubmed:24375720Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Onset latency of segmental dystonia after deep brain stimulation cessation: a randomized, double-blind crossover trial.</title><author><name sortKey="Levin, Johannes" sort="Levin, Johannes" uniqKey="Levin J" first="Johannes" last="Levin">Johannes Levin</name><affiliation><nlm:affiliation>Department of Neurology, Ludwig-Maximilians University Munich, Munich, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Singh, Arun" sort="Singh, Arun" uniqKey="Singh A" first="Arun" last="Singh">Arun Singh</name></author><author><name sortKey="Feddersen, Berend" sort="Feddersen, Berend" uniqKey="Feddersen B" first="Berend" last="Feddersen">Berend Feddersen</name></author><author><name sortKey="Mehrkens, Jan Hinnerk" sort="Mehrkens, Jan Hinnerk" uniqKey="Mehrkens J" first="Jan-Hinnerk" last="Mehrkens">Jan-Hinnerk Mehrkens</name></author><author><name sortKey="Botzel, Kai" sort="Botzel, Kai" uniqKey="Botzel K" first="Kai" last="Bötzel">Kai Bötzel</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2014">2014</date><idno type="RBID">pubmed:24375720</idno><idno type="pmid">24375720</idno><idno type="doi">10.1002/mds.25780</idno><idno type="wicri:Area/PubMed/Corpus">000630</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Onset latency of segmental dystonia after deep brain stimulation cessation: a randomized, double-blind crossover trial.</title><author><name sortKey="Levin, Johannes" sort="Levin, Johannes" uniqKey="Levin J" first="Johannes" last="Levin">Johannes Levin</name><affiliation><nlm:affiliation>Department of Neurology, Ludwig-Maximilians University Munich, Munich, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Singh, Arun" sort="Singh, Arun" uniqKey="Singh A" first="Arun" last="Singh">Arun Singh</name></author><author><name sortKey="Feddersen, Berend" sort="Feddersen, Berend" uniqKey="Feddersen B" first="Berend" last="Feddersen">Berend Feddersen</name></author><author><name sortKey="Mehrkens, Jan Hinnerk" sort="Mehrkens, Jan Hinnerk" uniqKey="Mehrkens J" first="Jan-Hinnerk" last="Mehrkens">Jan-Hinnerk Mehrkens</name></author><author><name sortKey="Botzel, Kai" sort="Botzel, Kai" uniqKey="Botzel K" first="Kai" last="Bötzel">Kai Bötzel</name></author></analytic><series><title level="j">Movement disorders : official journal of the Movement Disorder Society</title><idno type="eISSN">1531-8257</idno><imprint><date when="2014" type="published">2014</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Cross-Over Studies</term><term>Deep Brain Stimulation (adverse effects)</term><term>Double-Blind Method</term><term>Dystonia (etiology)</term><term>Dystonia (physiopathology)</term><term>Electrodes, Implanted</term><term>Globus Pallidus (physiology)</term><term>Humans</term><term>Treatment Outcome</term></keywords><keywords scheme="MESH" qualifier="adverse effects" xml:lang="en"><term>Deep Brain Stimulation</term></keywords><keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Dystonia</term></keywords><keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Globus Pallidus</term></keywords><keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Dystonia</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Cross-Over Studies</term><term>Double-Blind Method</term><term>Electrodes, Implanted</term><term>Humans</term><term>Treatment Outcome</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Deep brain stimulation (DBS) of the globus pallidus internus is an effective treatment for cervical dystonia (CD). Interestingly, the onset of initial DBS effects is significantly prolonged compared with that in other diseases, such as Parkinson's disease. The return of symptoms after cessation of DBS could be delayed as well, but this has not been studied systematically.</div></front></TEI><pubmed><MedlineCitation Owner="NLM" Status="MEDLINE"><PMID Version="1">24375720</PMID><DateCreated><Year>2014</Year><Month>06</Month><Day>13</Day></DateCreated><DateCompleted><Year>2015</Year><Month>02</Month><Day>26</Day></DateCompleted><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1531-8257</ISSN><JournalIssue CitedMedium="Internet"><Volume>29</Volume><Issue>7</Issue><PubDate><Year>2014</Year><Month>Jun</Month></PubDate></JournalIssue><Title>Movement disorders : official journal of the Movement Disorder Society</Title><ISOAbbreviation>Mov. Disord.</ISOAbbreviation></Journal><ArticleTitle>Onset latency of segmental dystonia after deep brain stimulation cessation: a randomized, double-blind crossover trial.</ArticleTitle><Pagination><MedlinePgn>944-9</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1002/mds.25780</ELocationID><Abstract><AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">Deep brain stimulation (DBS) of the globus pallidus internus is an effective treatment for cervical dystonia (CD). Interestingly, the onset of initial DBS effects is significantly prolonged compared with that in other diseases, such as Parkinson's disease. The return of symptoms after cessation of DBS could be delayed as well, but this has not been studied systematically.</AbstractText><AbstractText Label="METHODS" NlmCategory="METHODS">In patients who were treated for CD using DBS and had a good treatment effect, we compared interruption of DBS with sham-OFF in a randomized, double-blind crossover trial.</AbstractText><AbstractText Label="RESULTS" NlmCategory="RESULTS">We observed that dystonic features appeared within a few minutes at almost full intensity in all patients after the cessation of DBS.</AbstractText><AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">The almost immediate onset of dystonic features in our sample seems to exclude mechanisms with long time constants from the pathophysiology of dystonia. Thus, it is likely that, in these patients, an aberrant pattern of neural activity representing an inappropriate set point value for the position of the head is responsible for dystonia.</AbstractText><CopyrightInformation>© 2013 International Parkinson and Movement Disorder Society.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Levin</LastName><ForeName>Johannes</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Department of Neurology, Ludwig-Maximilians University Munich, Munich, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Singh</LastName><ForeName>Arun</ForeName><Initials>A</Initials></Author><Author ValidYN="Y"><LastName>Feddersen</LastName><ForeName>Berend</ForeName><Initials>B</Initials></Author><Author ValidYN="Y"><LastName>Mehrkens</LastName><ForeName>Jan-Hinnerk</ForeName><Initials>JH</Initials></Author><Author ValidYN="Y"><LastName>Bötzel</LastName><ForeName>Kai</ForeName><Initials>K</Initials></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D016449">Randomized Controlled Trial</PublicationType><PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2013</Year><Month>12</Month><Day>20</Day></ArticleDate></Article><MedlineJournalInfo><Country>United States</Country><MedlineTA>Mov Disord</MedlineTA><NlmUniqueID>8610688</NlmUniqueID><ISSNLinking>0885-3185</ISSNLinking></MedlineJournalInfo><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName MajorTopicYN="N" UI="D018592">Cross-Over Studies</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="Y" UI="D046690">Deep Brain Stimulation</DescriptorName><QualifierName MajorTopicYN="N" UI="Q000009">adverse effects</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D004311">Double-Blind Method</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D004421">Dystonia</DescriptorName><QualifierName MajorTopicYN="Y" UI="Q000209">etiology</QualifierName><QualifierName MajorTopicYN="N" UI="Q000503">physiopathology</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D004567">Electrodes, Implanted</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D005917">Globus Pallidus</DescriptorName><QualifierName MajorTopicYN="Y" UI="Q000502">physiology</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D006801">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D016896">Treatment Outcome</DescriptorName></MeshHeading></MeshHeadingList><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">Toronto Western Spasmodic Torticollis Rating Scale</Keyword><Keyword MajorTopicYN="N">deep brain stimulation</Keyword><Keyword MajorTopicYN="N">globus pallidus</Keyword><Keyword MajorTopicYN="N">segmental dystonia</Keyword></KeywordList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2013</Year><Month>1</Month><Day>7</Day></PubMedPubDate><PubMedPubDate PubStatus="revised"><Year>2013</Year><Month>10</Month><Day>6</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2013</Year><Month>10</Month><Day>28</Day></PubMedPubDate><PubMedPubDate PubStatus="aheadofprint"><Year>2013</Year><Month>12</Month><Day>20</Day></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2013</Year><Month>12</Month><Day>31</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2014</Year><Month>1</Month><Day>1</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2015</Year><Month>2</Month><Day>27</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">24375720</ArticleId><ArticleId IdType="doi">10.1002/mds.25780</ArticleId></ArticleIdList></PubmedData></pubmed></record>Pour manipuler ce document sous Unix (Dilib)
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