Electrophysiological evaluation of pharyngeal phase of swallowing in patients with Parkinson's disease
Identifieur interne : 004478 ( Main/Exploration ); précédent : 004477; suivant : 004479Electrophysiological evaluation of pharyngeal phase of swallowing in patients with Parkinson's disease
Auteurs : Cumhur Ertekin [Turquie] ; Sultan Tarlaci [Turquie] ; Ibrahim Aydogdu [Turquie] ; Nefati Kiylioglu [Turquie] ; Nur Yuceyar [Turquie] ; A. Bulent Turman [Australie] ; Yaprak Secil [Turquie] ; Figen Esmeli [Turquie]Source :
- Movement Disorders [ 0885-3185 ] ; 2002-09.
Descripteurs français
- Pascal (Inist)
- Wicri :
- topic : Homme.
English descriptors
- KwdEn :
- Adult, Aged, Aged, 80 and over, Cricoid Cartilage (physiopathology), Cricopharingeus muscle, Deglutition Disorders (diagnosis), Deglutition Disorders (etiology), Deglutition Disorders (physiopathology), Dysphagia, Electromyography, Exploration, Female, Human, Humans, Larynx (physiopathology), Male, Middle Aged, Parkinson Disease (complications), Parkinson disease, Parkinson's disease, Pharynx (physiopathology), Swallowing, Time Factors, cricopharyngeal muscle, electromyography, oropharyngeal dysphagia.
- MESH :
- complications : Parkinson Disease.
- diagnosis : Deglutition Disorders.
- etiology : Deglutition Disorders.
- physiopathology : Cricoid Cartilage, Deglutition Disorders, Larynx, Pharynx.
- Adult, Aged, Aged, 80 and over, Female, Humans, Male, Middle Aged, Time Factors.
Abstract
We studied the various physiological aspects of oropharyngeal swallowing in Parkinson's disease (PD). Fifty‐eight patients with PD were investigated by clinical and electrophysiological methods that measured the oropharyngeal phase of swallowing. All patients except 1 had mild to moderate degree of disability score. Dysphagia was demonstrated in 53% of all patients in whom the test of dysphagia limit was abnormal. All PD patients with or without dysphagia displayed the following abnormalities: (1) the triggering of the swallowing reflex was prolonged probably due to inadequate bolus control in the mouth and tongue and/or a specific delay in the execution of the swallowing reflex; (2) the duration of the pharyngeal reflex time was extremely prolonged due to slowness of the sequential muscle movements, especially those of the suprahyoid‐submental muscles; (3) cricopharyngeal muscle of the upper oesophageal sphincter was found to be electrophysiologically normal; and (4) the electrophysiological phenomena in PD patients could not be strongly correlated with the degree of the disability and clinical score of the PD. It was concluded that various motor disorders of PD have considerable influence on oropharyngeal swallowing: hypokinesia, reduced rate of spontaneous swallowing, and the slowness of segmented but coordinated sequential movements rather than any abnormalities in the central pattern generator of the bulbar center. Some compensatory mechanisms in the course of PD may explain the benign nature of swallowing disorder until the terminal stage of the disease. Similarly, the swallowing problems of PD are not only related with the dopamine deficiency; some other nondopaminergic mechanisms may also be involved. © 2002 Movement Disorder Society
Url:
DOI: 10.1002/mds.10240
Affiliations:
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Le document en format XML
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Bulent Turman</name><affiliation wicri:level="1"><country xml:lang="fr">Australie</country><wicri:regionArea>Department of Biomedical Sciences, University of Sydney</wicri:regionArea><wicri:noRegion>University of Sydney</wicri:noRegion></affiliation></author><author><name sortKey="Secil, Yaprak" sort="Secil, Yaprak" uniqKey="Secil Y" first="Yaprak" last="Secil">Yaprak Secil</name><affiliation wicri:level="1"><country xml:lang="fr">Turquie</country><wicri:regionArea>Department of Neurology, Ege University Medical School Hospital, Bornova, Izmir</wicri:regionArea><wicri:noRegion>Izmir</wicri:noRegion></affiliation></author><author><name sortKey="Esmeli, Figen" sort="Esmeli, Figen" uniqKey="Esmeli F" first="Figen" last="Esmeli">Figen Esmeli</name><affiliation wicri:level="1"><country xml:lang="fr">Turquie</country><wicri:regionArea>Department of Clinical Neurophysiology, Ege University Medical School Hospital, Bornova, Izmir</wicri:regionArea><wicri:noRegion>Izmir</wicri:noRegion></affiliation></author></analytic><monogr></monogr><series><title level="j">Movement Disorders</title><title level="j" type="sub">Official Journal of the Movement Disorder Society</title><title level="j" type="abbrev">Mov. Disord.</title><idno type="ISSN">0885-3185</idno><idno type="eISSN">1531-8257</idno><imprint><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><pubPlace>New York</pubPlace><date type="published" when="2002-09">2002-09</date><biblScope unit="vol">17</biblScope><biblScope unit="issue">5</biblScope><biblScope unit="page" from="942">942</biblScope><biblScope unit="page" to="949">949</biblScope></imprint><idno type="ISSN">0885-3185</idno></series><idno type="istex">442C89B4E4F1421B3051AD3379B4621B830F65B7</idno><idno type="DOI">10.1002/mds.10240</idno><idno type="ArticleID">MDS10240</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0885-3185</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term><term>Aged</term><term>Aged, 80 and over</term><term>Cricoid Cartilage (physiopathology)</term><term>Cricopharingeus muscle</term><term>Deglutition Disorders (diagnosis)</term><term>Deglutition Disorders (etiology)</term><term>Deglutition Disorders (physiopathology)</term><term>Dysphagia</term><term>Electromyography</term><term>Exploration</term><term>Female</term><term>Human</term><term>Humans</term><term>Larynx (physiopathology)</term><term>Male</term><term>Middle Aged</term><term>Parkinson Disease (complications)</term><term>Parkinson disease</term><term>Parkinson's disease</term><term>Pharynx (physiopathology)</term><term>Swallowing</term><term>Time Factors</term><term>cricopharyngeal muscle</term><term>electromyography</term><term>oropharyngeal dysphagia</term></keywords><keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Parkinson Disease</term></keywords><keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Deglutition Disorders</term></keywords><keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Deglutition Disorders</term></keywords><keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Cricoid Cartilage</term><term>Deglutition Disorders</term><term>Larynx</term><term>Pharynx</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adult</term><term>Aged</term><term>Aged, 80 and over</term><term>Female</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Time Factors</term></keywords><keywords scheme="Pascal" xml:lang="fr"><term>Dysphagie</term><term>Déglutition</term><term>Electromyographie</term><term>Exploration</term><term>Homme</term><term>Muscle cricopharyngien</term><term>Parkinson maladie</term></keywords><keywords scheme="Wicri" type="topic" xml:lang="fr"><term>Homme</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">We studied the various physiological aspects of oropharyngeal swallowing in Parkinson's disease (PD). Fifty‐eight patients with PD were investigated by clinical and electrophysiological methods that measured the oropharyngeal phase of swallowing. All patients except 1 had mild to moderate degree of disability score. Dysphagia was demonstrated in 53% of all patients in whom the test of dysphagia limit was abnormal. All PD patients with or without dysphagia displayed the following abnormalities: (1) the triggering of the swallowing reflex was prolonged probably due to inadequate bolus control in the mouth and tongue and/or a specific delay in the execution of the swallowing reflex; (2) the duration of the pharyngeal reflex time was extremely prolonged due to slowness of the sequential muscle movements, especially those of the suprahyoid‐submental muscles; (3) cricopharyngeal muscle of the upper oesophageal sphincter was found to be electrophysiologically normal; and (4) the electrophysiological phenomena in PD patients could not be strongly correlated with the degree of the disability and clinical score of the PD. It was concluded that various motor disorders of PD have considerable influence on oropharyngeal swallowing: hypokinesia, reduced rate of spontaneous swallowing, and the slowness of segmented but coordinated sequential movements rather than any abnormalities in the central pattern generator of the bulbar center. Some compensatory mechanisms in the course of PD may explain the benign nature of swallowing disorder until the terminal stage of the disease. Similarly, the swallowing problems of PD are not only related with the dopamine deficiency; some other nondopaminergic mechanisms may also be involved. © 2002 Movement Disorder Society</div></front></TEI><affiliations><list><country><li>Australie</li><li>Turquie</li></country></list><tree><country name="Turquie"><noRegion><name sortKey="Ertekin, Cumhur" sort="Ertekin, Cumhur" uniqKey="Ertekin C" first="Cumhur" last="Ertekin">Cumhur Ertekin</name></noRegion><name sortKey="Aydogdu, Ibrahim" sort="Aydogdu, Ibrahim" uniqKey="Aydogdu I" first="Ibrahim" last="Aydogdu">Ibrahim Aydogdu</name><name sortKey="Aydogdu, Ibrahim" sort="Aydogdu, Ibrahim" uniqKey="Aydogdu I" first="Ibrahim" last="Aydogdu">Ibrahim Aydogdu</name><name sortKey="Ertekin, Cumhur" sort="Ertekin, Cumhur" uniqKey="Ertekin C" first="Cumhur" last="Ertekin">Cumhur Ertekin</name><name sortKey="Esmeli, Figen" sort="Esmeli, Figen" uniqKey="Esmeli F" first="Figen" last="Esmeli">Figen Esmeli</name><name sortKey="Kiylioglu, Nefati" sort="Kiylioglu, Nefati" uniqKey="Kiylioglu N" first="Nefati" last="Kiylioglu">Nefati Kiylioglu</name><name sortKey="Secil, Yaprak" sort="Secil, Yaprak" uniqKey="Secil Y" first="Yaprak" last="Secil">Yaprak Secil</name><name sortKey="Tarlaci, Sultan" sort="Tarlaci, Sultan" uniqKey="Tarlaci S" first="Sultan" last="Tarlaci">Sultan Tarlaci</name><name sortKey="Yuceyar, Nur" sort="Yuceyar, Nur" uniqKey="Yuceyar N" first="Nur" last="Yuceyar">Nur Yuceyar</name></country><country name="Australie"><noRegion><name sortKey="Turman, A Bulent" sort="Turman, A Bulent" uniqKey="Turman A" first="A. Bulent" last="Turman">A. Bulent Turman</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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