Animal model of posthypoxic myoclonus: II. Neurochemical, pathologic, and pharmacologic characterization
Identifieur interne : 004B46 ( Main/Exploration ); précédent : 004B45; suivant : 004B47Animal model of posthypoxic myoclonus: II. Neurochemical, pathologic, and pharmacologic characterization
Auteurs : Anumantha G. Kanthasamy [États-Unis] ; Bang Q. Nguyen [États-Unis] ; Daniel D. Truong [États-Unis]Source :
- Movement Disorders [ 0885-3185 ] ; 2000-09.
Descripteurs français
- Pascal (Inist)
- Wicri :
- topic : Oxygène, Pharmacologie.
English descriptors
- KwdEn :
- Animal, Animal model, Animals, Anticonvulsant, Behavioral disorder, Brain (pathology), Brain (physiopathology), Brain Mapping, Cardiac arrest, Cardiocirculatory arrest, DDT, Disease Models, Animal, Epilepsies, Myoclonic (pathology), Epilepsies, Myoclonic (physiopathology), Exploration, Hypoxia, Hypoxia, Brain (pathology), Hypoxia, Brain (physiopathology), Lamotrigine, Male, Movement disorder, Myoclonus, Myoclonus (pathology), Myoclonus (physiopathology), Oxygen, Pathology, Pharmacology, Rat, Rats, Rats, Sprague-Dawley, Review, Riluzole, Serotonin, Serotonin (physiology), Symptomatology.
- MESH :
- chemical , physiology : Serotonin.
- pathology : Brain, Epilepsies, Myoclonic, Hypoxia, Brain, Myoclonus.
- physiopathology : Brain, Epilepsies, Myoclonic, Hypoxia, Brain, Myoclonus.
- Animals, Brain Mapping, Disease Models, Animal, Male, Rats, Rats, Sprague-Dawley.
Abstract
The sudden, brief, shock‐like, involuntary movements caused by active muscular contractions or inhibitions characterize myoclonus. It is manifested in a wide variety of pathologic conditions affecting the brain, spinal cord, or peripheral nerves, and is thought to be related to neuronal hyper‐excitability. The pathology, physiology, and pharmacology of myoclonus are not well understood as a result of the rarity of the disorder in people and the lack of a suitable animal model. Posthypoxic myoclonus is a major myoclonus syndrome which occurs as a result of severe cerebral ischemia/hypoxia. There has been tremendous interest in the development of a suitable animal model that reflects the etiology and clinical pathology of posthypoxic myoclonus. Recently, we have developed a new animal model of posthypoxic myoclonus in which rats were subjected to a mechanically induced cardiac arrest procedure. Herein, we describe the neurochemical, pharmacologic, and pathologic characteristics of this animal model of posthypoxic myoclonus.
Url:
DOI: 10.1002/mds.870150707
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Istex, to step Corpus: 001E00
- to stream Istex, to step Curation: 001E00
- to stream Istex, to step Checkpoint: 003347
- to stream Main, to step Merge: 007444
- to stream PascalFrancis, to step Corpus: 002C22
- to stream PascalFrancis, to step Curation: 000099
- to stream PascalFrancis, to step Checkpoint: 002C62
- to stream Main, to step Merge: 007654
- to stream PubMed, to step Corpus: 003F92
- to stream PubMed, to step Curation: 003F92
- to stream PubMed, to step Checkpoint: 004047
- to stream Ncbi, to step Merge: 000259
- to stream Ncbi, to step Curation: 000259
- to stream Ncbi, to step Checkpoint: 000259
- to stream Main, to step Merge: 007190
- to stream Main, to step Curation: 004B46
Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Animal model of posthypoxic myoclonus: II. Neurochemical, pathologic, and pharmacologic characterization</title>
<author><name sortKey="Kanthasamy, Anumantha G" sort="Kanthasamy, Anumantha G" uniqKey="Kanthasamy A" first="Anumantha G." last="Kanthasamy">Anumantha G. Kanthasamy</name>
</author>
<author><name sortKey="Nguyen, Bang Q" sort="Nguyen, Bang Q" uniqKey="Nguyen B" first="Bang Q." last="Nguyen">Bang Q. Nguyen</name>
</author>
<author><name sortKey="Truong, Daniel D" sort="Truong, Daniel D" uniqKey="Truong D" first="Daniel D." last="Truong">Daniel D. Truong</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">ISTEX</idno>
<idno type="RBID">ISTEX:9F594A31A342D2B1A5794ED146A3F6402F6B2266</idno>
<date when="2000" year="2000">2000</date>
<idno type="doi">10.1002/mds.870150707</idno>
<idno type="url">https://api.istex.fr/document/9F594A31A342D2B1A5794ED146A3F6402F6B2266/fulltext/pdf</idno>
<idno type="wicri:Area/Istex/Corpus">001E00</idno>
<idno type="wicri:Area/Istex/Curation">001E00</idno>
<idno type="wicri:Area/Istex/Checkpoint">003347</idno>
<idno type="wicri:doubleKey">0885-3185:2000:Kanthasamy A:animal:model:of</idno>
<idno type="wicri:Area/Main/Merge">007444</idno>
<idno type="wicri:source">INIST</idno>
<idno type="RBID">Pascal:00-0252427</idno>
<idno type="wicri:Area/PascalFrancis/Corpus">002C22</idno>
<idno type="wicri:Area/PascalFrancis/Curation">000099</idno>
<idno type="wicri:Area/PascalFrancis/Checkpoint">002C62</idno>
<idno type="wicri:doubleKey">0885-3185:2000:Kanthasamy A:animal:model:of</idno>
<idno type="wicri:Area/Main/Merge">007654</idno>
<idno type="wicri:source">PubMed</idno>
<idno type="RBID">pubmed:10755270</idno>
<idno type="wicri:Area/PubMed/Corpus">003F92</idno>
<idno type="wicri:Area/PubMed/Curation">003F92</idno>
<idno type="wicri:Area/PubMed/Checkpoint">004047</idno>
<idno type="wicri:Area/Ncbi/Merge">000259</idno>
<idno type="wicri:Area/Ncbi/Curation">000259</idno>
<idno type="wicri:Area/Ncbi/Checkpoint">000259</idno>
<idno type="wicri:doubleKey">0885-3185:2000:Kanthasamy A:animal:model:of</idno>
<idno type="wicri:Area/Main/Merge">007190</idno>
<idno type="wicri:Area/Main/Curation">004B46</idno>
<idno type="wicri:Area/Main/Exploration">004B46</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Animal model of posthypoxic myoclonus: II. Neurochemical, pathologic, and pharmacologic characterization</title>
<author><name sortKey="Kanthasamy, Anumantha G" sort="Kanthasamy, Anumantha G" uniqKey="Kanthasamy A" first="Anumantha G." last="Kanthasamy">Anumantha G. Kanthasamy</name>
<affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country>
<wicri:regionArea>The Parkinson's and Movement Disorder Institute, Long Beach Memorial Medical Center, Long Beach, California</wicri:regionArea>
<placeName><region type="state">Californie</region>
</placeName>
</affiliation>
<affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Orange Coast Memorial Medical Center, Fountain Valley, California</wicri:regionArea>
<placeName><region type="state">Californie</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Nguyen, Bang Q" sort="Nguyen, Bang Q" uniqKey="Nguyen B" first="Bang Q." last="Nguyen">Bang Q. Nguyen</name>
<affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country>
<wicri:regionArea>The Parkinson's and Movement Disorder Institute, Long Beach Memorial Medical Center, Long Beach, California</wicri:regionArea>
<placeName><region type="state">Californie</region>
</placeName>
</affiliation>
<affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Orange Coast Memorial Medical Center, Fountain Valley, California</wicri:regionArea>
<placeName><region type="state">Californie</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Truong, Daniel D" sort="Truong, Daniel D" uniqKey="Truong D" first="Daniel D." last="Truong">Daniel D. Truong</name>
<affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country>
<wicri:regionArea>The Parkinson's and Movement Disorder Institute, Long Beach Memorial Medical Center, Long Beach, California</wicri:regionArea>
<placeName><region type="state">Californie</region>
</placeName>
</affiliation>
<affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Orange Coast Memorial Medical Center, Fountain Valley, California</wicri:regionArea>
<placeName><region type="state">Californie</region>
</placeName>
</affiliation>
</author>
</analytic>
<monogr></monogr>
<series><title level="j">Movement Disorders</title>
<title level="j" type="abbrev">Mov. Disord.</title>
<idno type="ISSN">0885-3185</idno>
<idno type="eISSN">1531-8257</idno>
<imprint><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher>
<pubPlace>Hoboken</pubPlace>
<date type="published" when="2000-09">2000-09</date>
<biblScope unit="vol">15</biblScope>
<biblScope unit="issue">S1</biblScope>
<biblScope unit="supplement">S1</biblScope>
<biblScope unit="page" from="31">31</biblScope>
<biblScope unit="page" to="38">38</biblScope>
</imprint>
<idno type="ISSN">0885-3185</idno>
</series>
<idno type="istex">9F594A31A342D2B1A5794ED146A3F6402F6B2266</idno>
<idno type="DOI">10.1002/mds.870150707</idno>
<idno type="ArticleID">MDS870150707</idno>
</biblStruct>
</sourceDesc>
<seriesStmt><idno type="ISSN">0885-3185</idno>
</seriesStmt>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Animal</term>
<term>Animal model</term>
<term>Animals</term>
<term>Anticonvulsant</term>
<term>Behavioral disorder</term>
<term>Brain (pathology)</term>
<term>Brain (physiopathology)</term>
<term>Brain Mapping</term>
<term>Cardiac arrest</term>
<term>Cardiocirculatory arrest</term>
<term>DDT</term>
<term>Disease Models, Animal</term>
<term>Epilepsies, Myoclonic (pathology)</term>
<term>Epilepsies, Myoclonic (physiopathology)</term>
<term>Exploration</term>
<term>Hypoxia</term>
<term>Hypoxia, Brain (pathology)</term>
<term>Hypoxia, Brain (physiopathology)</term>
<term>Lamotrigine</term>
<term>Male</term>
<term>Movement disorder</term>
<term>Myoclonus</term>
<term>Myoclonus (pathology)</term>
<term>Myoclonus (physiopathology)</term>
<term>Oxygen</term>
<term>Pathology</term>
<term>Pharmacology</term>
<term>Rat</term>
<term>Rats</term>
<term>Rats, Sprague-Dawley</term>
<term>Review</term>
<term>Riluzole</term>
<term>Serotonin</term>
<term>Serotonin (physiology)</term>
<term>Symptomatology</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="physiology" xml:lang="en"><term>Serotonin</term>
</keywords>
<keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Brain</term>
<term>Epilepsies, Myoclonic</term>
<term>Hypoxia, Brain</term>
<term>Myoclonus</term>
</keywords>
<keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Brain</term>
<term>Epilepsies, Myoclonic</term>
<term>Hypoxia, Brain</term>
<term>Myoclonus</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Animals</term>
<term>Brain Mapping</term>
<term>Disease Models, Animal</term>
<term>Male</term>
<term>Rats</term>
<term>Rats, Sprague-Dawley</term>
</keywords>
<keywords scheme="Pascal" xml:lang="fr"><term>Anatomopathologie</term>
<term>Animal</term>
<term>Anticonvulsivant</term>
<term>Arrêt cardiocirculatoire</term>
<term>Article synthèse</term>
<term>Exploration</term>
<term>Hypoxie</term>
<term>Lamotrigine</term>
<term>Modèle animal</term>
<term>Myoclonie</term>
<term>Oxygène</term>
<term>Pharmacologie</term>
<term>Rat</term>
<term>Riluzole</term>
<term>Symptomatologie</term>
<term>Trouble comportement</term>
</keywords>
<keywords scheme="Wicri" type="topic" xml:lang="fr"><term>Oxygène</term>
<term>Pharmacologie</term>
</keywords>
</textClass>
<langUsage><language ident="en">en</language>
</langUsage>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">The sudden, brief, shock‐like, involuntary movements caused by active muscular contractions or inhibitions characterize myoclonus. It is manifested in a wide variety of pathologic conditions affecting the brain, spinal cord, or peripheral nerves, and is thought to be related to neuronal hyper‐excitability. The pathology, physiology, and pharmacology of myoclonus are not well understood as a result of the rarity of the disorder in people and the lack of a suitable animal model. Posthypoxic myoclonus is a major myoclonus syndrome which occurs as a result of severe cerebral ischemia/hypoxia. There has been tremendous interest in the development of a suitable animal model that reflects the etiology and clinical pathology of posthypoxic myoclonus. Recently, we have developed a new animal model of posthypoxic myoclonus in which rats were subjected to a mechanically induced cardiac arrest procedure. Herein, we describe the neurochemical, pharmacologic, and pathologic characteristics of this animal model of posthypoxic myoclonus.</div>
</front>
</TEI>
<affiliations><list><country><li>États-Unis</li>
</country>
<region><li>Californie</li>
</region>
</list>
<tree><country name="États-Unis"><region name="Californie"><name sortKey="Kanthasamy, Anumantha G" sort="Kanthasamy, Anumantha G" uniqKey="Kanthasamy A" first="Anumantha G." last="Kanthasamy">Anumantha G. Kanthasamy</name>
</region>
<name sortKey="Kanthasamy, Anumantha G" sort="Kanthasamy, Anumantha G" uniqKey="Kanthasamy A" first="Anumantha G." last="Kanthasamy">Anumantha G. Kanthasamy</name>
<name sortKey="Nguyen, Bang Q" sort="Nguyen, Bang Q" uniqKey="Nguyen B" first="Bang Q." last="Nguyen">Bang Q. Nguyen</name>
<name sortKey="Nguyen, Bang Q" sort="Nguyen, Bang Q" uniqKey="Nguyen B" first="Bang Q." last="Nguyen">Bang Q. Nguyen</name>
<name sortKey="Truong, Daniel D" sort="Truong, Daniel D" uniqKey="Truong D" first="Daniel D." last="Truong">Daniel D. Truong</name>
<name sortKey="Truong, Daniel D" sort="Truong, Daniel D" uniqKey="Truong D" first="Daniel D." last="Truong">Daniel D. Truong</name>
</country>
</tree>
</affiliations>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Santé/explor/MovDisordV3/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 004B46 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 004B46 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Wicri/Santé |area= MovDisordV3 |flux= Main |étape= Exploration |type= RBID |clé= ISTEX:9F594A31A342D2B1A5794ED146A3F6402F6B2266 |texte= Animal model of posthypoxic myoclonus: II. Neurochemical, pathologic, and pharmacologic characterization }}
![]() | This area was generated with Dilib version V0.6.23. | ![]() |