Is There an Increased Risk of Hip Fracture in Parkinson's Disease? A Nationwide Inpatient Sample
Identifieur interne : 001080 ( Main/Exploration ); précédent : 001079; suivant : 001081Is There an Increased Risk of Hip Fracture in Parkinson's Disease? A Nationwide Inpatient Sample
Auteurs : Rajib K. Bhattacharya [États-Unis] ; Richard M. Dubinsky [États-Unis] ; SUE MIN LAI [États-Unis] ; Hilary Dubinsky [États-Unis]Source :
- Movement disorders [ 0885-3185 ] ; 2012.
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- Pascal (Inist)
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Abstract
Objective: The aim of this study was to determine whether people with Parkinson's disease (PD) are overrepresented in a national cohort of hip-fracture admissions. Background: Frequent falls, combined with a higher rate of osteoporosis in people with PD, should lead to an increased risk of hip fracture. Methods: This work was a retrospective cohort analysis from the Nationwide Inpatient Sample from 1988 to 2007, a stratified sample of 20% of U.S. hospital admissions. Admissions with a primary diagnosis of acute hip fracture were identified, as was a subset with a secondary diagnosis of PD. Results: A total of 3.63% of 1,066,404 hip-fracture admissions had PD. When compared to the population of prevalence among patients with hip fracture, the prevalence of PD was up to 4.48 times (95% confidence interval [CI]: 4.46, 4.49) more than predicted, and when adjusted for gender and age, it was 4.02 (95% CI: 4.00, 4.03). Conclusions: In this 20-year nationwide sample of hip fractures, patients with PD were overrepresented by a factor of 4.
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Dubinsky</name><affiliation wicri:level="2"><inist:fA14 i1="02"><s1>Department of Neurology, University of Kansas Medical Center</s1><s2>Kansas City, Kansas</s2><s3>USA</s3><sZ>2 aut.</sZ><sZ>4 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">Kansas</region></placeName></affiliation></author><author><name sortKey="Sue Min Lai" sort="Sue Min Lai" uniqKey="Sue Min Lai" last="Sue Min Lai">SUE MIN LAI</name><affiliation wicri:level="2"><inist:fA14 i1="03"><s1>Department of Public Health and Preventive Medicine, University of Kansas Medical Center</s1><s2>Kansas City, Kansas</s2><s3>USA</s3><sZ>3 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">Kansas</region></placeName></affiliation></author><author><name sortKey="Dubinsky, Hilary" sort="Dubinsky, Hilary" uniqKey="Dubinsky H" first="Hilary" last="Dubinsky">Hilary Dubinsky</name><affiliation wicri:level="2"><inist:fA14 i1="02"><s1>Department of Neurology, University of Kansas Medical Center</s1><s2>Kansas City, Kansas</s2><s3>USA</s3><sZ>2 aut.</sZ><sZ>4 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">Kansas</region></placeName></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">INIST</idno><idno type="inist">12-0393086</idno><date when="2012">2012</date><idno type="stanalyst">PASCAL 12-0393086 INIST</idno><idno type="RBID">Pascal:12-0393086</idno><idno type="wicri:Area/PascalFrancis/Corpus">000073</idno><idno type="wicri:Area/PascalFrancis/Curation">002C41</idno><idno type="wicri:Area/PascalFrancis/Checkpoint">000153</idno><idno type="wicri:doubleKey">0885-3185:2012:Bhattacharya R:is:there:an</idno><idno type="wicri:Area/Main/Merge">001132</idno><idno type="wicri:Area/Main/Curation">001080</idno><idno type="wicri:Area/Main/Exploration">001080</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a">Is There an Increased Risk of Hip Fracture in Parkinson's Disease? A Nationwide Inpatient Sample</title><author><name sortKey="Bhattacharya, Rajib K" sort="Bhattacharya, Rajib K" uniqKey="Bhattacharya R" first="Rajib K." last="Bhattacharya">Rajib K. Bhattacharya</name><affiliation wicri:level="2"><inist:fA14 i1="01"><s1>Department of Internal Medicine, Division of Endocrinology, Metabolism, and Genetics, University of Kansas Medical Center</s1><s2>Kansas City, Kansas</s2><s3>USA</s3><sZ>1 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">Kansas</region></placeName></affiliation></author><author><name sortKey="Dubinsky, Richard M" sort="Dubinsky, Richard M" uniqKey="Dubinsky R" first="Richard M." last="Dubinsky">Richard M. Dubinsky</name><affiliation wicri:level="2"><inist:fA14 i1="02"><s1>Department of Neurology, University of Kansas Medical Center</s1><s2>Kansas City, Kansas</s2><s3>USA</s3><sZ>2 aut.</sZ><sZ>4 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">Kansas</region></placeName></affiliation></author><author><name sortKey="Sue Min Lai" sort="Sue Min Lai" uniqKey="Sue Min Lai" last="Sue Min Lai">SUE MIN LAI</name><affiliation wicri:level="2"><inist:fA14 i1="03"><s1>Department of Public Health and Preventive Medicine, University of Kansas Medical Center</s1><s2>Kansas City, Kansas</s2><s3>USA</s3><sZ>3 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">Kansas</region></placeName></affiliation></author><author><name sortKey="Dubinsky, Hilary" sort="Dubinsky, Hilary" uniqKey="Dubinsky H" first="Hilary" last="Dubinsky">Hilary Dubinsky</name><affiliation wicri:level="2"><inist:fA14 i1="02"><s1>Department of Neurology, University of Kansas Medical Center</s1><s2>Kansas City, Kansas</s2><s3>USA</s3><sZ>2 aut.</sZ><sZ>4 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">Kansas</region></placeName></affiliation></author></analytic><series><title level="j" type="main">Movement disorders</title><title level="j" type="abbreviated">Mov. disord.</title><idno type="ISSN">0885-3185</idno><imprint><date when="2012">2012</date></imprint></series></biblStruct></sourceDesc><seriesStmt><title level="j" type="main">Movement disorders</title><title level="j" type="abbreviated">Mov. disord.</title><idno type="ISSN">0885-3185</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Epidemiology</term><term>Fracture</term><term>Hip</term><term>Nervous system diseases</term><term>Osteoporosis</term><term>Parkinson disease</term><term>Risk factor</term></keywords><keywords scheme="Pascal" xml:lang="fr"><term>Fracture</term><term>Maladie de Parkinson</term><term>Ostéoporose</term><term>Pathologie du système nerveux</term><term>Facteur risque</term><term>Hanche</term><term>Epidémiologie</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Objective: The aim of this study was to determine whether people with Parkinson's disease (PD) are overrepresented in a national cohort of hip-fracture admissions. Background: Frequent falls, combined with a higher rate of osteoporosis in people with PD, should lead to an increased risk of hip fracture. Methods: This work was a retrospective cohort analysis from the Nationwide Inpatient Sample from 1988 to 2007, a stratified sample of 20% of U.S. hospital admissions. Admissions with a primary diagnosis of acute hip fracture were identified, as was a subset with a secondary diagnosis of PD. Results: A total of 3.63% of 1,066,404 hip-fracture admissions had PD. When compared to the population of prevalence among patients with hip fracture, the prevalence of PD was up to 4.48 times (95% confidence interval [CI]: 4.46, 4.49) more than predicted, and when adjusted for gender and age, it was 4.02 (95% CI: 4.00, 4.03). Conclusions: In this 20-year nationwide sample of hip fractures, patients with PD were overrepresented by a factor of 4.</div></front></TEI><affiliations><list><country><li>États-Unis</li></country><region><li>Kansas</li></region></list><tree><country name="États-Unis"><region name="Kansas"><name sortKey="Bhattacharya, Rajib K" sort="Bhattacharya, Rajib K" uniqKey="Bhattacharya R" first="Rajib K." last="Bhattacharya">Rajib K. Bhattacharya</name></region><name sortKey="Dubinsky, Hilary" sort="Dubinsky, Hilary" uniqKey="Dubinsky H" first="Hilary" last="Dubinsky">Hilary Dubinsky</name><name sortKey="Dubinsky, Richard M" sort="Dubinsky, Richard M" uniqKey="Dubinsky R" first="Richard M." last="Dubinsky">Richard M. Dubinsky</name><name sortKey="Sue Min Lai" sort="Sue Min Lai" uniqKey="Sue Min Lai" last="Sue Min Lai">SUE MIN LAI</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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