Cognitive impairment in multiple system atrophy
Identifieur interne : 000629 ( Main/Exploration ); précédent : 000628; suivant : 000630Cognitive impairment in multiple system atrophy
Auteurs : Iva Stankovic [Serbie] ; Florian Krismer [Autriche] ; Aleksandar Jesic [Serbie] ; Angelo Antonini [Italie] ; Thomas Benke [Autriche] ; Richard G. Brown [Royaume-Uni] ; David J. Burn [Royaume-Uni] ; Janice L. Holton [Royaume-Uni] ; Horacio Kaufmann [États-Unis] ; Vladimir S. Kostic [Serbie] ; Helen Ling [Royaume-Uni] ; Wassilios G. Meissner [France] ; Werner Poewe [Autriche] ; Marija Semnic [Serbie] ; Klaus Seppi [Autriche] ; Atsushi Takeda [Japon] ; Daniel Weintraub [États-Unis] ; Gregor K. Wenning [Autriche]Source :
- Movement disorders : official journal of the Movement Disorder Society [ 0885-3185 ] ; 2014.
English descriptors
- KwdEn :
- Animals, Cognition (physiology), Cognition Disorders (diagnosis), Cognition Disorders (etiology), Cognition Disorders (therapy), Dementia (diagnosis), Dementia (etiology), Humans, Memory (physiology), Multiple System Atrophy (complications), Multiple System Atrophy (diagnosis), Multiple System Atrophy (therapy), Neuropsychological Tests.
- MESH :
- complications : Multiple System Atrophy.
- diagnosis : Cognition Disorders, Dementia, Multiple System Atrophy.
- etiology : Cognition Disorders, Dementia.
- physiology : Cognition, Memory.
- therapy : Cognition Disorders, Multiple System Atrophy.
- Animals, Humans, Neuropsychological Tests.
Abstract
Consensus diagnostic criteria for multiple system atrophy consider dementia as a non-supporting feature, despite emerging evidence demonstrating that cognitive impairments are an integral part of the disease. Cognitive disturbances in multiple system atrophy occur across a wide spectrum from mild single domain deficits to impairments in multiple domains and even to frank dementia in some cases. Frontal-executive dysfunction is the most common presentation, while memory and visuospatial functions may also be impaired. Imaging and neuropathological findings support the concept that cognitive impairments in MSA originate from striatofrontal deafferentation with additional contributions from intrinsic cortical degeneration and cerebellar pathology. Based on a comprehensive evidence-based review we here propose future avenues of research that may ultimately lead to diagnostic criteria for cognitive impairment and dementia associated with multiple system atrophy.
Url:
DOI: 10.1002/mds.25880
PubMed: 24753321
PubMed Central: 4175376
Affiliations:
- Autriche, France, Italie, Japon, Royaume-Uni, Serbie, États-Unis
- Angleterre, Aquitaine, Aquitaine-Limousin-Poitou-Charentes, Grand Londres, Pennsylvanie, Tyrol (Land), État de New York
- Bordeaux, Innsbruck, Londres
- Université de médecine d'Innsbruck
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Le document en format XML
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</author>
<author><name sortKey="Weintraub, Daniel" sort="Weintraub, Daniel" uniqKey="Weintraub D" first="Daniel" last="Weintraub">Daniel Weintraub</name>
<affiliation wicri:level="2"><nlm:aff id="A11">Departments of Psychiatry and Neurology, Perelman School of Medicine at the University of Pennsylvania, and Parkinson's Disease Research, Education and Clinical Center, Philadelphia Veterans Affairs Medical Center, Philadelphia, Pennsylvania</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Pennsylvanie</region>
</placeName>
<wicri:cityArea>Departments of Psychiatry and Neurology, Perelman School of Medicine at the University of Pennsylvania, and Parkinson's Disease Research, Education and Clinical Center, Philadelphia Veterans Affairs Medical Center, Philadelphia</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Wenning, Gregor K" sort="Wenning, Gregor K" uniqKey="Wenning G" first="Gregor K." last="Wenning">Gregor K. Wenning</name>
<affiliation wicri:level="1"><nlm:aff id="A2">Department of Neurology, Innsbruck Medical University, Austria</nlm:aff>
<country xml:lang="fr">Autriche</country>
<wicri:regionArea>Department of Neurology, Innsbruck Medical University</wicri:regionArea>
<wicri:noRegion>Innsbruck Medical University</wicri:noRegion>
</affiliation>
</author>
</analytic>
<series><title level="j">Movement disorders : official journal of the Movement Disorder Society</title>
<idno type="ISSN">0885-3185</idno>
<idno type="eISSN">1531-8257</idno>
<imprint><date when="2014">2014</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Animals</term>
<term>Cognition (physiology)</term>
<term>Cognition Disorders (diagnosis)</term>
<term>Cognition Disorders (etiology)</term>
<term>Cognition Disorders (therapy)</term>
<term>Dementia (diagnosis)</term>
<term>Dementia (etiology)</term>
<term>Humans</term>
<term>Memory (physiology)</term>
<term>Multiple System Atrophy (complications)</term>
<term>Multiple System Atrophy (diagnosis)</term>
<term>Multiple System Atrophy (therapy)</term>
<term>Neuropsychological Tests</term>
</keywords>
<keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Multiple System Atrophy</term>
</keywords>
<keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Cognition Disorders</term>
<term>Dementia</term>
<term>Multiple System Atrophy</term>
</keywords>
<keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Cognition Disorders</term>
<term>Dementia</term>
</keywords>
<keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Cognition</term>
<term>Memory</term>
</keywords>
<keywords scheme="MESH" qualifier="therapy" xml:lang="en"><term>Cognition Disorders</term>
<term>Multiple System Atrophy</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Animals</term>
<term>Humans</term>
<term>Neuropsychological Tests</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en"><p id="P1">Consensus diagnostic criteria for multiple system atrophy consider dementia as a non-supporting feature, despite emerging evidence demonstrating that cognitive impairments are an integral part of the disease. Cognitive disturbances in multiple system atrophy occur across a wide spectrum from mild single domain deficits to impairments in multiple domains and even to frank dementia in some cases. Frontal-executive dysfunction is the most common presentation, while memory and visuospatial functions may also be impaired. Imaging and neuropathological findings support the concept that cognitive impairments in MSA originate from striatofrontal deafferentation with additional contributions from intrinsic cortical degeneration and cerebellar pathology. Based on a comprehensive evidence-based review we here propose future avenues of research that may ultimately lead to diagnostic criteria for cognitive impairment and dementia associated with multiple system atrophy.</p>
</div>
</front>
</TEI>
<affiliations><list><country><li>Autriche</li>
<li>France</li>
<li>Italie</li>
<li>Japon</li>
<li>Royaume-Uni</li>
<li>Serbie</li>
<li>États-Unis</li>
</country>
<region><li>Angleterre</li>
<li>Aquitaine</li>
<li>Aquitaine-Limousin-Poitou-Charentes</li>
<li>Grand Londres</li>
<li>Pennsylvanie</li>
<li>Tyrol (Land)</li>
<li>État de New York</li>
</region>
<settlement><li>Bordeaux</li>
<li>Innsbruck</li>
<li>Londres</li>
</settlement>
<orgName><li>Université de médecine d'Innsbruck</li>
</orgName>
</list>
<tree><country name="Serbie"><noRegion><name sortKey="Stankovic, Iva" sort="Stankovic, Iva" uniqKey="Stankovic I" first="Iva" last="Stankovic">Iva Stankovic</name>
</noRegion>
<name sortKey="Jesic, Aleksandar" sort="Jesic, Aleksandar" uniqKey="Jesic A" first="Aleksandar" last="Jesic">Aleksandar Jesic</name>
<name sortKey="Kostic, Vladimir S" sort="Kostic, Vladimir S" uniqKey="Kostic V" first="Vladimir S." last="Kostic">Vladimir S. Kostic</name>
<name sortKey="Semnic, Marija" sort="Semnic, Marija" uniqKey="Semnic M" first="Marija" last="Semnic">Marija Semnic</name>
</country>
<country name="Autriche"><noRegion><name sortKey="Krismer, Florian" sort="Krismer, Florian" uniqKey="Krismer F" first="Florian" last="Krismer">Florian Krismer</name>
</noRegion>
<name sortKey="Benke, Thomas" sort="Benke, Thomas" uniqKey="Benke T" first="Thomas" last="Benke">Thomas Benke</name>
<name sortKey="Poewe, Werner" sort="Poewe, Werner" uniqKey="Poewe W" first="Werner" last="Poewe">Werner Poewe</name>
<name sortKey="Seppi, Klaus" sort="Seppi, Klaus" uniqKey="Seppi K" first="Klaus" last="Seppi">Klaus Seppi</name>
<name sortKey="Wenning, Gregor K" sort="Wenning, Gregor K" uniqKey="Wenning G" first="Gregor K." last="Wenning">Gregor K. Wenning</name>
</country>
<country name="Italie"><noRegion><name sortKey="Antonini, Angelo" sort="Antonini, Angelo" uniqKey="Antonini A" first="Angelo" last="Antonini">Angelo Antonini</name>
</noRegion>
</country>
<country name="Royaume-Uni"><noRegion><name sortKey="Brown, Richard G" sort="Brown, Richard G" uniqKey="Brown R" first="Richard G." last="Brown">Richard G. Brown</name>
</noRegion>
<name sortKey="Burn, David J" sort="Burn, David J" uniqKey="Burn D" first="David J." last="Burn">David J. Burn</name>
<name sortKey="Holton, Janice L" sort="Holton, Janice L" uniqKey="Holton J" first="Janice L." last="Holton">Janice L. Holton</name>
<name sortKey="Ling, Helen" sort="Ling, Helen" uniqKey="Ling H" first="Helen" last="Ling">Helen Ling</name>
</country>
<country name="États-Unis"><region name="État de New York"><name sortKey="Kaufmann, Horacio" sort="Kaufmann, Horacio" uniqKey="Kaufmann H" first="Horacio" last="Kaufmann">Horacio Kaufmann</name>
</region>
<name sortKey="Weintraub, Daniel" sort="Weintraub, Daniel" uniqKey="Weintraub D" first="Daniel" last="Weintraub">Daniel Weintraub</name>
</country>
<country name="France"><region name="Aquitaine-Limousin-Poitou-Charentes"><name sortKey="Meissner, Wassilios G" sort="Meissner, Wassilios G" uniqKey="Meissner W" first="Wassilios G." last="Meissner">Wassilios G. Meissner</name>
</region>
</country>
<country name="Japon"><noRegion><name sortKey="Takeda, Atsushi" sort="Takeda, Atsushi" uniqKey="Takeda A" first="Atsushi" last="Takeda">Atsushi Takeda</name>
</noRegion>
</country>
</tree>
</affiliations>
</record>
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