Restless legs syndrome and Parkinson's disease in men
Identifieur interne : 001A39 ( Main/Exploration ); précédent : 001A38; suivant : 001A40Restless legs syndrome and Parkinson's disease in men
Auteurs : Xiang Gao [États-Unis] ; Michael A. Schwarzschild [États-Unis] ; Eilis J. O'Reilly [États-Unis] ; Hao Wang [États-Unis] ; Alberto Ascherio [États-Unis]Source :
- Movement Disorders [ 0885-3185 ] ; 2010-11-15.
Descripteurs français
- Wicri :
- geographic : États-Unis.
English descriptors
- KwdEn :
- Adult, Aged, Comorbidity, Health Surveys, Humans, Logistic Models, Male, Middle Aged, Odds Ratio, Parkinson Disease (epidemiology), Parkinson's disease, Prevalence, Questionnaires, Restless Legs Syndrome (diagnosis), Restless Legs Syndrome (epidemiology), United States (epidemiology), men, restless legs syndrome.
- MESH :
- geographic , epidemiology : United States.
- diagnosis : Restless Legs Syndrome.
- epidemiology : Parkinson Disease, Restless Legs Syndrome.
- Adult, Aged, Comorbidity, Health Surveys, Humans, Logistic Models, Male, Middle Aged, Odds Ratio, Prevalence, Questionnaires.
Abstract
We examined whether men with restless legs syndrome (RLS) have a higher prevalence of Parkinson's disease (PD) among 23,119 US participants of the Health Professional Follow‐up Study who were free of diabetes and arthritis. RLS was assessed using a set of standardized questions recommended by the International RLS Study Group. PD cases were identified by self‐reported questionnaires and confirmed by review of medical records. Compared to men without RLS, multivariate‐adjusted odds ratios for PD were 1.1 (95% confidence interval: 0.4, 3.0) for men with RLS symptoms 5–14 times per month and 3.09 (95% confidence interval: 1.5, 6.2; P trend = 0.003) for those with symptoms 15 times or more per month, after adjusting for age, smoking, use of antidepressant, and other covariates. In conclusion, men with RLS are more likely to have concurrent PD. Prospective studies are warranted to clarify the temporal relationship between RLS and PD. © 2010 Movement Disorder Society
Url:
- https://api.istex.fr/document/1F75677F8A72242F46E44990DC076AB064BEF8AD/fulltext/pdf
- http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3114885
DOI: 10.1002/mds.23256
Affiliations:
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Le document en format XML
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<front><div type="abstract" xml:lang="en">We examined whether men with restless legs syndrome (RLS) have a higher prevalence of Parkinson's disease (PD) among 23,119 US participants of the Health Professional Follow‐up Study who were free of diabetes and arthritis. RLS was assessed using a set of standardized questions recommended by the International RLS Study Group. PD cases were identified by self‐reported questionnaires and confirmed by review of medical records. Compared to men without RLS, multivariate‐adjusted odds ratios for PD were 1.1 (95% confidence interval: 0.4, 3.0) for men with RLS symptoms 5–14 times per month and 3.09 (95% confidence interval: 1.5, 6.2; P trend = 0.003) for those with symptoms 15 times or more per month, after adjusting for age, smoking, use of antidepressant, and other covariates. In conclusion, men with RLS are more likely to have concurrent PD. Prospective studies are warranted to clarify the temporal relationship between RLS and PD. © 2010 Movement Disorder Society</div>
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<name sortKey="Gao, Xiang" sort="Gao, Xiang" uniqKey="Gao X" first="Xiang" last="Gao">Xiang Gao</name>
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