Bilateral deep brain stimulation of the globus pallidus internus in tardive dystonia
Identifieur interne : 002976 ( Main/Exploration ); précédent : 002975; suivant : 002977Bilateral deep brain stimulation of the globus pallidus internus in tardive dystonia
Auteurs : Wataru Sako [Japon] ; Satoshi Goto [Japon] ; Hideki Shimazu [Japon] ; Nagako Murase [Japon] ; Kazuhito Matsuzaki [Japon] ; Tetsuya Tamura [Japon] ; Hideo Mure [Japon] ; Yusuke Tomogane [Japon] ; Norio Arita [Japon] ; Hiroo Yoshikawa [Japon] ; Shinji Nagahiro [Japon] ; Ryuji Kaji [Japon]Source :
- Movement Disorders [ 0885-3185 ] ; 2008-10-15.
Descripteurs français
- Pascal (Inist)
English descriptors
- KwdEn :
- MESH :
- methods : Deep Brain Stimulation.
- physiology : Globus Pallidus.
- therapy : Dystonia.
- Adult, Biophysics, Female, Humans, Male, Middle Aged, Treatment Outcome.
Abstract
Tardive dystonia is a disabling movement disorder as a consequence of exposure to neuroleptic drugs. We followed 6 patients with medically refractory tardive dystonia treated by bilateral globus pallidus internus (GPi) deep brain stimulation (DBS) for 21 ± 18 months. At last follow‐up, the Burke‐Fahn‐Marsden Dystonia Rating Scale (BFMDRS) motor score improved by 86% ± 14%, and the BFMDRS disability score improved by 80% ± 12%. Bilateral GPi‐DBS is a beneficial therapeutic option for the long‐term relief of tardive dystonia. © 2008 Movement Disorder Society
Url:
DOI: 10.1002/mds.22100
Affiliations:
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<term>Deep brain stimulation</term>
<term>Dystonia</term>
<term>Dystonia (therapy)</term>
<term>Female</term>
<term>Globus Pallidus (physiology)</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Nervous system diseases</term>
<term>Treatment Outcome</term>
<term>deep brain stimulation</term>
<term>globus pallidus internus</term>
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<term>Middle Aged</term>
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<front><div type="abstract" xml:lang="en">Tardive dystonia is a disabling movement disorder as a consequence of exposure to neuroleptic drugs. We followed 6 patients with medically refractory tardive dystonia treated by bilateral globus pallidus internus (GPi) deep brain stimulation (DBS) for 21 ± 18 months. At last follow‐up, the Burke‐Fahn‐Marsden Dystonia Rating Scale (BFMDRS) motor score improved by 86% ± 14%, and the BFMDRS disability score improved by 80% ± 12%. Bilateral GPi‐DBS is a beneficial therapeutic option for the long‐term relief of tardive dystonia. © 2008 Movement Disorder Society</div>
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<name sortKey="Matsuzaki, Kazuhito" sort="Matsuzaki, Kazuhito" uniqKey="Matsuzaki K" first="Kazuhito" last="Matsuzaki">Kazuhito Matsuzaki</name>
<name sortKey="Murase, Nagako" sort="Murase, Nagako" uniqKey="Murase N" first="Nagako" last="Murase">Nagako Murase</name>
<name sortKey="Mure, Hideo" sort="Mure, Hideo" uniqKey="Mure H" first="Hideo" last="Mure">Hideo Mure</name>
<name sortKey="Nagahiro, Shinji" sort="Nagahiro, Shinji" uniqKey="Nagahiro S" first="Shinji" last="Nagahiro">Shinji Nagahiro</name>
<name sortKey="Shimazu, Hideki" sort="Shimazu, Hideki" uniqKey="Shimazu H" first="Hideki" last="Shimazu">Hideki Shimazu</name>
<name sortKey="Tamura, Tetsuya" sort="Tamura, Tetsuya" uniqKey="Tamura T" first="Tetsuya" last="Tamura">Tetsuya Tamura</name>
<name sortKey="Tomogane, Yusuke" sort="Tomogane, Yusuke" uniqKey="Tomogane Y" first="Yusuke" last="Tomogane">Yusuke Tomogane</name>
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