Bilateral deep brain stimulation of the globus pallidus internus in tardive dystonia
Identifieur interne : 001756 ( Istex/Curation ); précédent : 001755; suivant : 001757Bilateral deep brain stimulation of the globus pallidus internus in tardive dystonia
Auteurs : Wataru Sako [Japon] ; Satoshi Goto [Japon] ; Hideki Shimazu [Japon] ; Nagako Murase [Japon] ; Kazuhito Matsuzaki [Japon] ; Tetsuya Tamura [Japon] ; Hideo Mure [Japon] ; Yusuke Tomogane [Japon] ; Norio Arita [Japon] ; Hiroo Yoshikawa [Japon] ; Shinji Nagahiro [Japon] ; Ryuji Kaji [Japon]Source :
- Movement Disorders [ 0885-3185 ] ; 2008-10-15.
English descriptors
Abstract
Tardive dystonia is a disabling movement disorder as a consequence of exposure to neuroleptic drugs. We followed 6 patients with medically refractory tardive dystonia treated by bilateral globus pallidus internus (GPi) deep brain stimulation (DBS) for 21 ± 18 months. At last follow‐up, the Burke‐Fahn‐Marsden Dystonia Rating Scale (BFMDRS) motor score improved by 86% ± 14%, and the BFMDRS disability score improved by 80% ± 12%. Bilateral GPi‐DBS is a beneficial therapeutic option for the long‐term relief of tardive dystonia. © 2008 Movement Disorder Society
Url:
DOI: 10.1002/mds.22100
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<front><div type="abstract" xml:lang="en">Tardive dystonia is a disabling movement disorder as a consequence of exposure to neuroleptic drugs. We followed 6 patients with medically refractory tardive dystonia treated by bilateral globus pallidus internus (GPi) deep brain stimulation (DBS) for 21 ± 18 months. At last follow‐up, the Burke‐Fahn‐Marsden Dystonia Rating Scale (BFMDRS) motor score improved by 86% ± 14%, and the BFMDRS disability score improved by 80% ± 12%. Bilateral GPi‐DBS is a beneficial therapeutic option for the long‐term relief of tardive dystonia. © 2008 Movement Disorder Society</div>
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