Unified Huntington's disease rating scale: Reliability and consistency
Identifieur interne : 005561 ( Main/Exploration ); précédent : 005560; suivant : 005562Unified Huntington's disease rating scale: Reliability and consistency
Auteurs :Source :
- Movement Disorders [ 0885-3185 ] ; 1996-03.
English descriptors
- KwdEn :
- Activities of Daily Living (classification), Activities of Daily Living (psychology), Adolescent, Adult, Aged, Aged, 80 and over, Behavioral abnormalities, Child, Clinical research, Cognitive function, Cohort Studies, Female, Follow-Up Studies, Functional capacity, Humans, Huntington Disease (diagnosis), Huntington Disease (genetics), Huntington Disease (psychology), Huntington's disease, Male, Middle Aged, Neuropsychological Tests (statistics & numerical data), Observer Variation, Prospective Studies, Psychometrics, Reproducibility of Results.
- MESH :
- classification : Activities of Daily Living.
- diagnosis : Huntington Disease.
- genetics : Huntington Disease.
- psychology : Activities of Daily Living, Huntington Disease.
- statistics & numerical data : Neuropsychological Tests.
- Adolescent, Adult, Aged, Aged, 80 and over, Child, Cohort Studies, Female, Follow-Up Studies, Humans, Male, Middle Aged, Observer Variation, Prospective Studies, Psychometrics, Reproducibility of Results.
Abstract
The Unified Huntington's disease Rating Scale (UHDRS) was developed as a clinical rating scale to assess four domains of clinical performance and capacity in HD: motor function, cognitive function, behavioral abnormalities, and functional capacity. We assessed the internal consistency and the intercorrelations for the four domains and examined changes in ratings over time. We also performed an interrater reliability study of the motor assessment. We found there was a high degree of internal consistency within each of the domains of the UHDRS and that there were significant intercorrelations between the domains of the UHDRS, with the exception of the total behavioral score. There was an excellent degree of interrater reliability for the motor scores. Our limited longitudinal database indicates that the UHDRS may be useful for tracking changes in the clinical features of HD over time. The UHDRS assesses relevant clinical features of HD and appears to be appropriate for repeated administration during clinical studies.
Url:
DOI: 10.1002/mds.870110204
Affiliations:
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Disord.</title><idno type="ISSN">0885-3185</idno><idno type="eISSN">1531-8257</idno><imprint><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><pubPlace>Hoboken</pubPlace><date type="published" when="1996-03">1996-03</date><biblScope unit="vol">11</biblScope><biblScope unit="issue">2</biblScope><biblScope unit="page" from="136">136</biblScope><biblScope unit="page" to="142">142</biblScope></imprint><idno type="ISSN">0885-3185</idno></series><idno type="istex">F93C238ED8CF01CC170C0B11BDA808524E9CE6D2</idno><idno type="DOI">10.1002/mds.870110204</idno><idno type="ArticleID">MDS870110204</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0885-3185</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Activities of Daily Living (classification)</term><term>Activities of Daily Living (psychology)</term><term>Adolescent</term><term>Adult</term><term>Aged</term><term>Aged, 80 and over</term><term>Behavioral abnormalities</term><term>Child</term><term>Clinical research</term><term>Cognitive function</term><term>Cohort Studies</term><term>Female</term><term>Follow-Up Studies</term><term>Functional capacity</term><term>Humans</term><term>Huntington Disease (diagnosis)</term><term>Huntington Disease (genetics)</term><term>Huntington Disease (psychology)</term><term>Huntington's disease</term><term>Male</term><term>Middle Aged</term><term>Neuropsychological Tests (statistics & numerical data)</term><term>Observer Variation</term><term>Prospective Studies</term><term>Psychometrics</term><term>Reproducibility of Results</term></keywords><keywords scheme="MESH" qualifier="classification" xml:lang="en"><term>Activities of Daily Living</term></keywords><keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Huntington Disease</term></keywords><keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Huntington Disease</term></keywords><keywords scheme="MESH" qualifier="psychology" xml:lang="en"><term>Activities of Daily Living</term><term>Huntington Disease</term></keywords><keywords scheme="MESH" qualifier="statistics & numerical data" xml:lang="en"><term>Neuropsychological Tests</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adolescent</term><term>Adult</term><term>Aged</term><term>Aged, 80 and over</term><term>Child</term><term>Cohort Studies</term><term>Female</term><term>Follow-Up Studies</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Observer Variation</term><term>Prospective Studies</term><term>Psychometrics</term><term>Reproducibility of Results</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">The Unified Huntington's disease Rating Scale (UHDRS) was developed as a clinical rating scale to assess four domains of clinical performance and capacity in HD: motor function, cognitive function, behavioral abnormalities, and functional capacity. We assessed the internal consistency and the intercorrelations for the four domains and examined changes in ratings over time. We also performed an interrater reliability study of the motor assessment. We found there was a high degree of internal consistency within each of the domains of the UHDRS and that there were significant intercorrelations between the domains of the UHDRS, with the exception of the total behavioral score. There was an excellent degree of interrater reliability for the motor scores. Our limited longitudinal database indicates that the UHDRS may be useful for tracking changes in the clinical features of HD over time. The UHDRS assesses relevant clinical features of HD and appears to be appropriate for repeated administration during clinical studies.</div></front></TEI><affiliations><list></list><tree></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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