End of day dyskinesia in advanced Parkinson's disease can be eliminated by bilateral subthalamic nucleus or globus pallidus deep brain stimulation
Identifieur interne : 003449 ( Main/Exploration ); précédent : 003448; suivant : 003450End of day dyskinesia in advanced Parkinson's disease can be eliminated by bilateral subthalamic nucleus or globus pallidus deep brain stimulation
Auteurs : Diana Apetauerova [États-Unis] ; R. Kevin Ryan [États-Unis] ; Susie I. Ro [États-Unis] ; Jeffrey Arle [États-Unis] ; Jay Shils [États-Unis] ; Efstathios Papavassiliou [États-Unis] ; Daniel Tarsy [États-Unis]Source :
- Movement Disorders [ 0885-3185 ] ; 2006-08.
Descripteurs français
- Pascal (Inist)
English descriptors
- KwdEn :
- Advanced stage, DBS, Deep Brain Stimulation, Deep brain stimulation, Dyskinesia, Dyskinesias (etiology), Dyskinesias (therapy), Female, Functional Laterality, Globus Pallidus, Humans, Middle Aged, Nervous system diseases, Parkinson Disease (therapy), Parkinson disease, Parkinson's disease, Subthalamic Nucleus, Subthalamic nucleus, deep brain stimulation, end of dose dyskinesia.
- MESH :
- etiology : Dyskinesias.
- therapy : Dyskinesias, Parkinson Disease.
- Deep Brain Stimulation, Female, Functional Laterality, Globus Pallidus, Humans, Middle Aged, Subthalamic Nucleus.
Abstract
We report the therapeutic effects of deep brain stimulation (DBS) in 2 patients with Parkinson's disease (PD) with severe end of dose dyskinesia that was resistant to medical therapy. In both patients, severe, end of day ballistic dyskinesias occurred when the last levodopa dose of the day was wearing off. Globus pallidus (GPi) DBS in 1 case and subthalamic (STN) DBS in the second case produced full resolution of end of day dyskinesia. © 2006 Movement Disorder Society
Url:
DOI: 10.1002/mds.20896
Affiliations:
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Le document en format XML
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<front><div type="abstract" xml:lang="en">We report the therapeutic effects of deep brain stimulation (DBS) in 2 patients with Parkinson's disease (PD) with severe end of dose dyskinesia that was resistant to medical therapy. In both patients, severe, end of day ballistic dyskinesias occurred when the last levodopa dose of the day was wearing off. Globus pallidus (GPi) DBS in 1 case and subthalamic (STN) DBS in the second case produced full resolution of end of day dyskinesia. © 2006 Movement Disorder Society</div>
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