MovDisordV3, Main, Curation, bibRecord, 002232

Levosulpiride‐induced movement disorders

Identifieur interne : 002232 ( Main/Curation ); précédent : 002231; suivant : 002233

Levosulpiride‐induced movement disorders

Auteurs : Hae-Won Shin [Corée du Sud] ; Mi J. Kim [Corée du Sud] ; Jong S. Kim [Corée du Sud] ; Myoung C. Lee [Corée du Sud] ; Sun J. Chung [Corée du Sud]

Source :

Movement Disorders [ 0885-3185 ] ; 2009-11-15.

RBID : ISTEX:0E863B81DEB3FE5A3F083702B586A9FCC29E9D9C

Descripteurs français

Pascal (Inist)
- Abus de substance, Dyskinésie, Lévosulpiride, Parkinsonisme, Pathologie du système nerveux, Tremblement.

English descriptors

KwdEn :
- Adult, Aged, Aged, 80 and over, Antipsychotic Agents (adverse effects), Brain (pathology), Dyskinesia, Female, Humans, Levosulpiride, Magnetic Resonance Imaging (methods), Male, Middle Aged, Movement Disorders (classification), Movement Disorders (diagnosis), Movement Disorders (etiology), Nervous system diseases, Parkinson Disease (etiology), Parkinsonism, Retrospective Studies, Substance abuse, Sulpiride (adverse effects), Sulpiride (analogs & derivatives), Tremor, Tremor (chemically induced), drug‐induced movement disorders, dyskinesia, levosulpiride, tremor.
MESH :
- chemical , adverse effects : Antipsychotic Agents, Sulpiride.
- chemical , analogs & derivatives : Sulpiride.
- chemically induced : Tremor.
- classification : Movement Disorders.
- diagnosis : Movement Disorders.
- etiology : Movement Disorders, Parkinson Disease.
- methods : Magnetic Resonance Imaging.
- pathology : Brain.
- Adult, Aged, Aged, 80 and over, Female, Humans, Male, Middle Aged, Retrospective Studies.

Abstract

Levosulpiride is a substituted benzamide that is widely used for the management of dyspepsia and emesis. However, little is known about levosulpiride‐induced movement disorders (LIM). The aim of this study was to investigate the clinical characteristics of patients with LIM. Among 132 consecutive patients who were diagnosed with drug‐induced movement disorders between January 2002 and March 2008, 91 patients with LIM were identified and their medical records reviewed. Seventy‐eight (85.7%) patients were aged more than 60 years. The most common LIM was parkinsonism (LIP) (n = 85, 93.4%), followed by tardive dyskinesia (n = 9, 9.9%) and isolated tremor (n = 3, 3.3%). Twenty‐one (24.7%) of the 85 patients with LIP were rated as Hoehn and Yahr stage III–V. The oro‐lingual area was the only body part that was involved by tardive dyskinesia. LIM persisted after withdrawal of levosulpiride in 48.1% of patients with LIP, 66.7% with dyskinesia, and none with isolated tremor. None of clinical and MRI features predicted the reversibility of LIP. Levosulpiride frequently causes drug‐induced movement disorders, presenting mainly with LIP followed by lower face dyskinesia. The symptoms are often severe, and irreversible even after the withdrawal of levosulpiride. Physicians should be cautious in using levosulpiride, especially in elderly patients. © 2009 Movement Disorder Society

Url:

https://api.istex.fr/document/0E863B81DEB3FE5A3F083702B586A9FCC29E9D9C/fulltext/pdf

DOI: 10.1002/mds.22805

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ISTEX:0E863B81DEB3FE5A3F083702B586A9FCC29E9D9C

Le document en format XML

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<front><div type="abstract" xml:lang="en">Levosulpiride is a substituted benzamide that is widely used for the management of dyspepsia and emesis. However, little is known about levosulpiride‐induced movement disorders (LIM). The aim of this study was to investigate the clinical characteristics of patients with LIM. Among 132 consecutive patients who were diagnosed with drug‐induced movement disorders between January 2002 and March 2008, 91 patients with LIM were identified and their medical records reviewed. Seventy‐eight (85.7%) patients were aged more than 60 years. The most common LIM was parkinsonism (LIP) (n = 85, 93.4%), followed by tardive dyskinesia (n = 9, 9.9%) and isolated tremor (n = 3, 3.3%). Twenty‐one (24.7%) of the 85 patients with LIP were rated as Hoehn and Yahr stage III–V. The oro‐lingual area was the only body part that was involved by tardive dyskinesia. LIM persisted after withdrawal of levosulpiride in 48.1% of patients with LIP, 66.7% with dyskinesia, and none with isolated tremor. None of clinical and MRI features predicted the reversibility of LIP. Levosulpiride frequently causes drug‐induced movement disorders, presenting mainly with LIP followed by lower face dyskinesia. The symptoms are often severe, and irreversible even after the withdrawal of levosulpiride. Physicians should be cautious in using levosulpiride, especially in elderly patients. © 2009 Movement Disorder Society</div>
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<front><div type="abstract" xml:lang="en">Levosulpiride is a substituted benzamide that is widely used for the management of dyspepsia and emesis. However, little is known about levosulpiride-induced movement disorders (LIM). The aim of this study was to investigate the clinical characteristics of patients with LIM. Among 1 32 consecutive patients who were diagnosed with drug-induced movement disorders between January 2002 and March 2008, 91 patients with LIM were identified and their medical records reviewed. Seventy-eight (85.7%) patients were aged more than 60 years. The most common LIM was parkinsonism (LIP) (n = 85, 93.4%), followed by tardive dyskinesia (n = 9, 9.9%) and isolated tremor (n = 3, 3.3%). Twenty-one (24.7%) of the 85 patients with LIP were rated as Hoehn and Yahr stage III-V. The oro-lingual area was the only body part that was involved by tardive dyskinesia. LIM persisted after withdrawal of levosulpiride in 48.1 % of patients with LIP, 66.7% with dyskinesia, and none with isolated tremor. None of clinical and MRI features predicted the reversibility of LIP. Levosulpiride frequently causes drug-induced movement disorders, presenting mainly with LIP followed by lower face dyskinesia. The symptoms are often severe, and irreversible even after the withdrawal of levosulpiride. Physicians should be cautious in using levosulpiride, especially in elderly patients.</div>
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<front><div type="abstract" xml:lang="en">Levosulpiride is a substituted benzamide that is widely used for the management of dyspepsia and emesis. However, little is known about levosulpiride‐induced movement disorders (LIM). The aim of this study was to investigate the clinical characteristics of patients with LIM. Among 132 consecutive patients who were diagnosed with drug‐induced movement disorders between January 2002 and March 2008, 91 patients with LIM were identified and their medical records reviewed. Seventy‐eight (85.7%) patients were aged more than 60 years. The most common LIM was parkinsonism (LIP) (n = 85, 93.4%), followed by tardive dyskinesia (n = 9, 9.9%) and isolated tremor (n = 3, 3.3%). Twenty‐one (24.7%) of the 85 patients with LIP were rated as Hoehn and Yahr stage III–V. The oro‐lingual area was the only body part that was involved by tardive dyskinesia. LIM persisted after withdrawal of levosulpiride in 48.1% of patients with LIP, 66.7% with dyskinesia, and none with isolated tremor. None of clinical and MRI features predicted the reversibility of LIP. Levosulpiride frequently causes drug‐induced movement disorders, presenting mainly with LIP followed by lower face dyskinesia. The symptoms are often severe, and irreversible even after the withdrawal of levosulpiride. Physicians should be cautious in using levosulpiride, especially in elderly patients. © 2009 Movement Disorder Society</div>
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	Movement Disorders (revue)
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Movement Disorders (revue)

Levosulpiride‐induced movement disorders

Levosulpiride‐induced movement disorders

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