Decision making in Parkinson's disease: Analysis of behavioral and physiological patterns in the Iowa gambling task
Identifieur interne : 001808 ( Istex/Curation ); précédent : 001807; suivant : 001809Decision making in Parkinson's disease: Analysis of behavioral and physiological patterns in the Iowa gambling task
Auteurs : Mutsutaka Kobayakawa [Japon] ; Shinichi Koyama [Japon] ; Masaru Mimura [Japon] ; Mitsuru Kawamura [Japon]Source :
- Movement Disorders [ 0885-3185 ] ; 2008-03-15.
English descriptors
- KwdEn :
Abstract
Recent studies suggest that social recognition processes are affected by Parkinson's disease (PD). However, whether PD patients exhibit behavioral changes is still controversial. The purpose of the present study was to examine the decision making of PD patients performing the Iowa Gambling Task (IGT). We recruited a large number of early, nondemented PD patients for the IGT. We also recorded the skin conductance responses (SCRs) during the task as a measure of emotional arousal. Compared with the normal control (NC) subjects, PD patients selected more disadvantageous decks in the IGT, and their SCRs were lower than those of NC subjects before making decisions and after receiving reward or punishment. The tendency toward risky choices was not correlated with age, education, global cognitive function, or the severity of the disease. These results confirmed that the decision making of PD patients was affected by the disease, rather than by other cognitive functions; moreover, such behavior was related to lower emotional responses. Behavioral and SCR patterns of PD patients were similar to those of amygdala‐damaged patients. The response bias toward risky choices in PD may be explained by the dysfunction of the amygdala, which is known to be involved in risk evaluation. © 2007 Movement Disorder Society
Url:
DOI: 10.1002/mds.21865
Links toward previous steps (curation, corpus...)
- to stream Istex, to step Corpus: Pour aller vers cette notice dans l'étape Curation :001808
Links to Exploration step
ISTEX:E56B642AB05CE15DEFB44A21BD273470A883D11BLe document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Decision making in Parkinson's disease: Analysis of behavioral and physiological patterns in the Iowa gambling task</title>
<author><name sortKey="Kobayakawa, Mutsutaka" sort="Kobayakawa, Mutsutaka" uniqKey="Kobayakawa M" first="Mutsutaka" last="Kobayakawa">Mutsutaka Kobayakawa</name>
<affiliation wicri:level="1"><mods:affiliation>Department of Neurology, Showa University School of Medicine, Tokyo, Japan</mods:affiliation>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>Department of Neurology, Showa University School of Medicine, Tokyo</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Koyama, Shinichi" sort="Koyama, Shinichi" uniqKey="Koyama S" first="Shinichi" last="Koyama">Shinichi Koyama</name>
<affiliation wicri:level="1"><mods:affiliation>Department of Neurology, Showa University School of Medicine, Tokyo, Japan</mods:affiliation>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>Department of Neurology, Showa University School of Medicine, Tokyo</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><mods:affiliation>Design Psychology Unit, Department of Design Science, Graduate School of Engineering, Chiba University, Chiba, Japan</mods:affiliation>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>Design Psychology Unit, Department of Design Science, Graduate School of Engineering, Chiba University, Chiba</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Mimura, Masaru" sort="Mimura, Masaru" uniqKey="Mimura M" first="Masaru" last="Mimura">Masaru Mimura</name>
<affiliation wicri:level="1"><mods:affiliation>Department of Neuropsychiatry, Showa University School of Medicine, Tokyo, Japan</mods:affiliation>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>Department of Neuropsychiatry, Showa University School of Medicine, Tokyo</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Kawamura, Mitsuru" sort="Kawamura, Mitsuru" uniqKey="Kawamura M" first="Mitsuru" last="Kawamura">Mitsuru Kawamura</name>
<affiliation wicri:level="1"><mods:affiliation>Department of Neurology, Showa University School of Medicine, Tokyo, Japan</mods:affiliation>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>Department of Neurology, Showa University School of Medicine, Tokyo</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><mods:affiliation>Core Research for Evolutional Science and Technology (CREST), Japan Science and Technology Agency (JST), Saitama, Japan</mods:affiliation>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>Core Research for Evolutional Science and Technology (CREST), Japan Science and Technology Agency (JST), Saitama</wicri:regionArea>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">ISTEX</idno>
<idno type="RBID">ISTEX:E56B642AB05CE15DEFB44A21BD273470A883D11B</idno>
<date when="2008" year="2008">2008</date>
<idno type="doi">10.1002/mds.21865</idno>
<idno type="url">https://api.istex.fr/document/E56B642AB05CE15DEFB44A21BD273470A883D11B/fulltext/pdf</idno>
<idno type="wicri:Area/Istex/Corpus">001808</idno>
<idno type="wicri:Area/Istex/Curation">001808</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Decision making in Parkinson's disease: Analysis of behavioral and physiological patterns in the Iowa gambling task</title>
<author><name sortKey="Kobayakawa, Mutsutaka" sort="Kobayakawa, Mutsutaka" uniqKey="Kobayakawa M" first="Mutsutaka" last="Kobayakawa">Mutsutaka Kobayakawa</name>
<affiliation wicri:level="1"><mods:affiliation>Department of Neurology, Showa University School of Medicine, Tokyo, Japan</mods:affiliation>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>Department of Neurology, Showa University School of Medicine, Tokyo</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Koyama, Shinichi" sort="Koyama, Shinichi" uniqKey="Koyama S" first="Shinichi" last="Koyama">Shinichi Koyama</name>
<affiliation wicri:level="1"><mods:affiliation>Department of Neurology, Showa University School of Medicine, Tokyo, Japan</mods:affiliation>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>Department of Neurology, Showa University School of Medicine, Tokyo</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><mods:affiliation>Design Psychology Unit, Department of Design Science, Graduate School of Engineering, Chiba University, Chiba, Japan</mods:affiliation>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>Design Psychology Unit, Department of Design Science, Graduate School of Engineering, Chiba University, Chiba</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Mimura, Masaru" sort="Mimura, Masaru" uniqKey="Mimura M" first="Masaru" last="Mimura">Masaru Mimura</name>
<affiliation wicri:level="1"><mods:affiliation>Department of Neuropsychiatry, Showa University School of Medicine, Tokyo, Japan</mods:affiliation>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>Department of Neuropsychiatry, Showa University School of Medicine, Tokyo</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Kawamura, Mitsuru" sort="Kawamura, Mitsuru" uniqKey="Kawamura M" first="Mitsuru" last="Kawamura">Mitsuru Kawamura</name>
<affiliation wicri:level="1"><mods:affiliation>Department of Neurology, Showa University School of Medicine, Tokyo, Japan</mods:affiliation>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>Department of Neurology, Showa University School of Medicine, Tokyo</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><mods:affiliation>Core Research for Evolutional Science and Technology (CREST), Japan Science and Technology Agency (JST), Saitama, Japan</mods:affiliation>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>Core Research for Evolutional Science and Technology (CREST), Japan Science and Technology Agency (JST), Saitama</wicri:regionArea>
</affiliation>
</author>
</analytic>
<monogr></monogr>
<series><title level="j">Movement Disorders</title>
<title level="j" type="sub">Official Journal of the Movement Disorder Society</title>
<title level="j" type="abbrev">Mov. Disord.</title>
<idno type="ISSN">0885-3185</idno>
<idno type="eISSN">1531-8257</idno>
<imprint><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher>
<pubPlace>Hoboken</pubPlace>
<date type="published" when="2008-03-15">2008-03-15</date>
<biblScope unit="vol">23</biblScope>
<biblScope unit="issue">4</biblScope>
<biblScope unit="page" from="547">547</biblScope>
<biblScope unit="page" to="552">552</biblScope>
</imprint>
<idno type="ISSN">0885-3185</idno>
</series>
<idno type="istex">E56B642AB05CE15DEFB44A21BD273470A883D11B</idno>
<idno type="DOI">10.1002/mds.21865</idno>
<idno type="ArticleID">MDS21865</idno>
</biblStruct>
</sourceDesc>
<seriesStmt><idno type="ISSN">0885-3185</idno>
</seriesStmt>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Iowa gambling task</term>
<term>Parkinson's disease</term>
<term>decision‐making</term>
<term>skin conductance response</term>
<term>social cognition</term>
</keywords>
</textClass>
<langUsage><language ident="en">en</language>
</langUsage>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">Recent studies suggest that social recognition processes are affected by Parkinson's disease (PD). However, whether PD patients exhibit behavioral changes is still controversial. The purpose of the present study was to examine the decision making of PD patients performing the Iowa Gambling Task (IGT). We recruited a large number of early, nondemented PD patients for the IGT. We also recorded the skin conductance responses (SCRs) during the task as a measure of emotional arousal. Compared with the normal control (NC) subjects, PD patients selected more disadvantageous decks in the IGT, and their SCRs were lower than those of NC subjects before making decisions and after receiving reward or punishment. The tendency toward risky choices was not correlated with age, education, global cognitive function, or the severity of the disease. These results confirmed that the decision making of PD patients was affected by the disease, rather than by other cognitive functions; moreover, such behavior was related to lower emotional responses. Behavioral and SCR patterns of PD patients were similar to those of amygdala‐damaged patients. The response bias toward risky choices in PD may be explained by the dysfunction of the amygdala, which is known to be involved in risk evaluation. © 2007 Movement Disorder Society</div>
</front>
</TEI>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Santé/explor/MovDisordV3/Data/Istex/Curation
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 001808 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Istex/Curation/biblio.hfd -nk 001808 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Wicri/Santé |area= MovDisordV3 |flux= Istex |étape= Curation |type= RBID |clé= ISTEX:E56B642AB05CE15DEFB44A21BD273470A883D11B |texte= Decision making in Parkinson's disease: Analysis of behavioral and physiological patterns in the Iowa gambling task }}
![]() | This area was generated with Dilib version V0.6.23. | ![]() |