Movement Disorders (revue)

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Eyelid movements during blinking in patients with Parkinson's disease

Identifieur interne : 003344 ( Istex/Corpus ); précédent : 003343; suivant : 003345

Eyelid movements during blinking in patients with Parkinson's disease

Auteurs : Marko Korošec ; Ignac Zidar ; Dik Reits ; Craig Evinger ; Frans Vanderwerf

Source :

RBID : ISTEX:698FB06DAA7DED13EFD0649DEEF2A2313746A857

English descriptors

Abstract

We examined eyelid movements during spontaneous, voluntary, and trigeminal reflex blinks in 16 patients with mild to moderate Parkinson's disease (PD) off medication and 14 controls. Voluntary and reflex blink amplitudes tended to be smaller than normal for PD patients, whereas eyelid kinematics (amplitude–maximum velocity relationship) for all three blink types were normal. Spontaneous blink rate was less than normal for 10 patients and abnormally high for 6 patients. A significant positive correlation between spontaneous blink amplitude and blink rate was found. These observations suggest that PD modifies the gain of a premotor blink circuit shared by spontaneous, voluntary, and reflex blinks. © 2006 Movement Disorder Society

Url:
DOI: 10.1002/mds.20930

Links to Exploration step

ISTEX:698FB06DAA7DED13EFD0649DEEF2A2313746A857

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<title>Eyelid movements during blinking in patients with Parkinson's disease</title>
</titleInfo>
<titleInfo type="abbreviated" lang="en">
<title>Eyelid Movements During Blinking in PD</title>
</titleInfo>
<titleInfo type="alternative" contentType="CDATA" lang="en">
<title>Eyelid movements during blinking in patients with Parkinson's disease</title>
</titleInfo>
<name type="personal">
<namePart type="given">Marko</namePart>
<namePart type="family">Korošec</namePart>
<namePart type="termsOfAddress">MD, MSc</namePart>
<affiliation>Institute of Clinical Neurophysiology, Division of Neurology, University Medical Center, Ljubljana, Slovenia</affiliation>
<description>Correspondence: Institute of Clinical Neurophysiology, Division of Neurology, University Medical Center, Zaloška 7, SI‐1525 Ljubljana, Slovenia</description>
<role>
<roleTerm type="text">author</roleTerm>
</role>
</name>
<name type="personal">
<namePart type="given">Ignac</namePart>
<namePart type="family">Zidar</namePart>
<namePart type="termsOfAddress">BSc</namePart>
<affiliation>Institute of Clinical Neurophysiology, Division of Neurology, University Medical Center, Ljubljana, Slovenia</affiliation>
<role>
<roleTerm type="text">author</roleTerm>
</role>
</name>
<name type="personal">
<namePart type="given">Dik</namePart>
<namePart type="family">Reits</namePart>
<namePart type="termsOfAddress">PhD</namePart>
<affiliation>Department of Neuroscience, Erasmus Medical Center, Rotterdam, The Netherlands</affiliation>
<role>
<roleTerm type="text">author</roleTerm>
</role>
</name>
<name type="personal">
<namePart type="given">Craig</namePart>
<namePart type="family">Evinger</namePart>
<namePart type="termsOfAddress">PhD</namePart>
<affiliation>Departments of Neurobiology & Behavior and Ophthalmology, State University of New York Stony Brook, Stony Brook, New York, USA</affiliation>
<role>
<roleTerm type="text">author</roleTerm>
</role>
</name>
<name type="personal">
<namePart type="given">Frans</namePart>
<namePart type="family">VanderWerf</namePart>
<namePart type="termsOfAddress">PhD</namePart>
<affiliation>Department of Neuroscience, Erasmus Medical Center, Rotterdam, The Netherlands</affiliation>
<role>
<roleTerm type="text">author</roleTerm>
</role>
</name>
<typeOfResource>text</typeOfResource>
<genre authority="originalCategForm">article</genre>
<originInfo>
<publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher>
<place>
<placeTerm type="text">Hoboken</placeTerm>
</place>
<dateIssued encoding="w3cdtf">2006-08</dateIssued>
<dateCaptured encoding="w3cdtf">2005-06-28</dateCaptured>
<dateValid encoding="w3cdtf">2005-12-23</dateValid>
<copyrightDate encoding="w3cdtf">2006</copyrightDate>
</originInfo>
<language>
<languageTerm type="code" authority="rfc3066">en</languageTerm>
<languageTerm type="code" authority="iso639-2b">eng</languageTerm>
</language>
<physicalDescription>
<internetMediaType>text/html</internetMediaType>
<extent unit="figures">2</extent>
<extent unit="tables">2</extent>
<extent unit="references">14</extent>
<extent unit="words">2611</extent>
</physicalDescription>
<abstract lang="en">We examined eyelid movements during spontaneous, voluntary, and trigeminal reflex blinks in 16 patients with mild to moderate Parkinson's disease (PD) off medication and 14 controls. Voluntary and reflex blink amplitudes tended to be smaller than normal for PD patients, whereas eyelid kinematics (amplitude–maximum velocity relationship) for all three blink types were normal. Spontaneous blink rate was less than normal for 10 patients and abnormally high for 6 patients. A significant positive correlation between spontaneous blink amplitude and blink rate was found. These observations suggest that PD modifies the gain of a premotor blink circuit shared by spontaneous, voluntary, and reflex blinks. © 2006 Movement Disorder Society</abstract>
<note type="funding">NATO Science Program Collaborative Linkage Grant - No. LST.CLG.978872; </note>
<note type="funding">National Eye Institute - No. EY07391; </note>
<subject lang="en">
<genre>Keywords</genre>
<topic>Parkinson's disease</topic>
<topic>eyelid movements</topic>
<topic>blink kinematics</topic>
<topic>blink rate</topic>
</subject>
<relatedItem type="host">
<titleInfo>
<title>Movement Disorders</title>
<subTitle>Official Journal of the Movement Disorder Society</subTitle>
</titleInfo>
<titleInfo type="abbreviated">
<title>Mov. Disord.</title>
</titleInfo>
<subject>
<genre>article category</genre>
<topic>Brief Report</topic>
</subject>
<identifier type="ISSN">0885-3185</identifier>
<identifier type="eISSN">1531-8257</identifier>
<identifier type="DOI">10.1002/(ISSN)1531-8257</identifier>
<identifier type="PublisherID">MDS</identifier>
<part>
<date>2006</date>
<detail type="volume">
<caption>vol.</caption>
<number>21</number>
</detail>
<detail type="issue">
<caption>no.</caption>
<number>8</number>
</detail>
<extent unit="pages">
<start>1248</start>
<end>1251</end>
<total>4</total>
</extent>
</part>
</relatedItem>
<identifier type="istex">698FB06DAA7DED13EFD0649DEEF2A2313746A857</identifier>
<identifier type="DOI">10.1002/mds.20930</identifier>
<identifier type="ArticleID">MDS20930</identifier>
<accessCondition type="use and reproduction" contentType="copyright">Copyright © 2006 Movement Disorder Society</accessCondition>
<recordInfo>
<recordOrigin>Wiley Subscription Services, Inc., A Wiley Company</recordOrigin>
<recordContentSource>WILEY</recordContentSource>
</recordInfo>
</mods>
</metadata>
<serie></serie>
</istex>
</record>

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