Elemental mercury poisoning probably causes cortical myoclonus
Identifieur interne : 003116 ( Istex/Corpus ); précédent : 003115; suivant : 003117Elemental mercury poisoning probably causes cortical myoclonus
Auteurs : Mona Ragothaman ; Girish Kulkarni ; Valappil V. Ashraf ; Pramod K. Pal ; Yasha Chickabasavaiah ; Susarla K. Shankar ; Srikanth S. Govindappa ; Parthasarthy Satishchandra ; Uday B. MuthaneSource :
- Movement Disorders [ 0885-3185 ] ; 2007-10-15.
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Abstract
Mercury toxicity causes postural tremors, commonly referred to as “mercurial tremors,” and cerebellar dysfunction. A 23‐year woman, 2 years after injecting herself with elemental mercury developed disabling generalized myoclonus and ataxia. Electrophysiological studies confirmed the myoclonus was probably of cortical origin. Her deficits progressed over 2 years and improved after subcutaneous mercury deposits at the injection site were surgically cleared. Myoclonus of cortical origin has never been described in mercury poisoning. It is important to ask patients presenting with jerks about exposure to elemental mercury even if they have a progressive illness, as it is a potentially reversible condition as in our patient. © 2007 Movement Disorder Society
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DOI: 10.1002/mds.21641
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A 23‐year woman, 2 years after injecting herself with elemental mercury developed disabling generalized myoclonus and ataxia. Electrophysiological studies confirmed the myoclonus was probably of cortical origin. Her deficits progressed over 2 years and improved after subcutaneous mercury deposits at the injection site were surgically cleared. Myoclonus of cortical origin has never been described in mercury poisoning. It is important to ask patients presenting with jerks about exposure to elemental mercury even if they have a progressive illness, as it is a potentially reversible condition as in our patient. © 2007 Movement Disorder Society</div></front></TEI><istex><corpusName>wiley</corpusName><author><json:item><name>Mona Ragothaman MBBS</name><affiliations><json:string>Department of Neurology, National Institute of Mental Health & Neurosciences, Bangalore, India</json:string></affiliations></json:item><json:item><name>Girish Kulkarni DM</name><affiliations><json:string>Department of Neurology, National Institute of Mental Health & Neurosciences, Bangalore, India</json:string><json:string>Department of Neurology, Malabar Institute of Medical Sciences, Calicut, India</json:string><json:string>Department of Neuropathology, National Institute of Mental Health & Neurosciences, Bangalore, India</json:string><json:string>Department of Neuroradiology, National Institute of Mental Health & Neurosciences, Bangalore, India</json:string></affiliations></json:item><json:item><name>Valappil V. Ashraf DM</name><affiliations><json:string>Department of Neurology, Malabar Institute of Medical Sciences, Calicut, India</json:string></affiliations></json:item><json:item><name>Pramod K. Pal DM</name><affiliations><json:string>Department of Neurology, National Institute of Mental Health & Neurosciences, Bangalore, India</json:string></affiliations></json:item><json:item><name>Yasha Chickabasavaiah MD</name><affiliations><json:string>Department of Neuropathology, National Institute of Mental Health & Neurosciences, Bangalore, India</json:string></affiliations></json:item><json:item><name>Susarla K. Shankar MD</name><affiliations><json:string>Department of Neuropathology, National Institute of Mental Health & Neurosciences, Bangalore, India</json:string></affiliations></json:item><json:item><name>Srikanth S. Govindappa MD</name><affiliations><json:string>Department of Neuroradiology, National Institute of Mental Health & Neurosciences, Bangalore, India</json:string></affiliations></json:item><json:item><name>Parthasarthy Satishchandra DM</name><affiliations><json:string>Department of Neurology, National Institute of Mental Health & Neurosciences, Bangalore, India</json:string></affiliations></json:item><json:item><name>Uday B. Muthane DM</name><affiliations><json:string>Department of Neurology, National Institute of Mental Health & Neurosciences, Bangalore, India</json:string></affiliations></json:item></author><subject><json:item><lang><json:string>eng</json:string></lang><value>elemental mercury</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>Cortical myoclonus</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>mercury poisoning</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>mercurial tremors</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>cerebellar ataxia</value></json:item></subject><language><json:string>eng</json:string></language><abstract>Mercury toxicity causes postural tremors, commonly referred to as “mercurial tremors,” and cerebellar dysfunction. A 23‐year woman, 2 years after injecting herself with elemental mercury developed disabling generalized myoclonus and ataxia. Electrophysiological studies confirmed the myoclonus was probably of cortical origin. Her deficits progressed over 2 years and improved after subcutaneous mercury deposits at the injection site were surgically cleared. Myoclonus of cortical origin has never been described in mercury poisoning. 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creatorRole="author" affiliationRef="#af1"><personName><givenNames>Pramod K.</givenNames><familyName>Pal</familyName><degrees>DM</degrees></personName></creator><creator xml:id="au5" creatorRole="author" affiliationRef="#af3"><personName><givenNames>Yasha</givenNames><familyName>Chickabasavaiah</familyName><degrees>MD</degrees></personName></creator><creator xml:id="au6" creatorRole="author" affiliationRef="#af3"><personName><givenNames>Susarla K.</givenNames><familyName>Shankar</familyName><degrees>MD</degrees></personName></creator><creator xml:id="au7" creatorRole="author" affiliationRef="#af4"><personName><givenNames>Srikanth S.</givenNames><familyName>Govindappa</familyName><degrees>MD</degrees></personName></creator><creator xml:id="au8" creatorRole="author" affiliationRef="#af1"><personName><givenNames>Parthasarthy</givenNames><familyName>Satishchandra</familyName><degrees>DM</degrees></personName></creator><creator xml:id="au9" creatorRole="author" affiliationRef="#af1" corresponding="yes"><personName><givenNames>Uday B.</givenNames><familyName>Muthane</familyName><degrees>DM</degrees></personName><contactDetails><email>umuthane@usa.net</email></contactDetails></creator></creators><affiliationGroup><affiliation xml:id="af1" countryCode="IN" type="organization"><unparsedAffiliation>Department of Neurology, National Institute of Mental Health & Neurosciences, Bangalore, India</unparsedAffiliation></affiliation><affiliation xml:id="af2" countryCode="IN" type="organization"><unparsedAffiliation>Department of Neurology, Malabar Institute of Medical Sciences, Calicut, India</unparsedAffiliation></affiliation><affiliation xml:id="af3" countryCode="IN" type="organization"><unparsedAffiliation>Department of Neuropathology, National Institute of Mental Health & Neurosciences, Bangalore, India</unparsedAffiliation></affiliation><affiliation xml:id="af4" countryCode="IN" type="organization"><unparsedAffiliation>Department of Neuroradiology, National Institute of Mental Health & Neurosciences, Bangalore, India</unparsedAffiliation></affiliation></affiliationGroup><keywordGroup xml:lang="en" type="author"><keyword xml:id="kwd1">elemental mercury</keyword><keyword xml:id="kwd2">Cortical myoclonus</keyword><keyword xml:id="kwd3">mercury poisoning</keyword><keyword xml:id="kwd4">mercurial tremors</keyword><keyword xml:id="kwd5">cerebellar ataxia</keyword></keywordGroup><supportingInformation><p> This article includes supplementary video clips, available online at <url href="http://www.interscience.wiley.com/jpages/0885-3185/suppmat"> http://www.interscience.wiley.com/jpages/0885–3185/suppmat </url></p></supportingInformation><abstractGroup><abstract type="main" xml:lang="en"><title type="main">Abstract</title><p>Mercury toxicity causes postural tremors, commonly referred to as “mercurial tremors,” and cerebellar dysfunction. A 23‐year woman, 2 years after injecting herself with elemental mercury developed disabling generalized myoclonus and ataxia. Electrophysiological studies confirmed the myoclonus was probably of cortical origin. Her deficits progressed over 2 years and improved after subcutaneous mercury deposits at the injection site were surgically cleared. Myoclonus of cortical origin has never been described in mercury poisoning. It is important to ask patients presenting with jerks about exposure to elemental mercury even if they have a progressive illness, as it is a potentially reversible condition as in our patient. © 2007 Movement Disorder Society</p></abstract></abstractGroup></contentMeta></header></component></istex:document></istex:metadataXml><!--Version 0.6 générée le 3-12-2015--><mods version="3.6"><titleInfo lang="en"><title>Elemental mercury poisoning probably causes cortical myoclonus</title></titleInfo><titleInfo type="abbreviated" lang="en"><title>Chronic Elemental Mercury Poisoning</title></titleInfo><titleInfo type="alternative" contentType="CDATA" lang="en"><title>Elemental mercury poisoning probably causes cortical myoclonus</title></titleInfo><name type="personal"><namePart type="given">Mona</namePart><namePart type="family">Ragothaman</namePart><namePart type="termsOfAddress">MBBS</namePart><affiliation>Department of Neurology, National Institute of Mental Health & Neurosciences, Bangalore, India</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Girish</namePart><namePart type="family">Kulkarni</namePart><namePart type="termsOfAddress">DM</namePart><affiliation>Department of Neurology, National Institute of Mental Health & Neurosciences, Bangalore, India</affiliation><affiliation>Department of Neurology, Malabar Institute of Medical Sciences, Calicut, India</affiliation><affiliation>Department of Neuropathology, National Institute of Mental Health & Neurosciences, Bangalore, India</affiliation><affiliation>Department of Neuroradiology, National Institute of Mental Health & Neurosciences, Bangalore, India</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Valappil V.</namePart><namePart type="family">Ashraf</namePart><namePart type="termsOfAddress">DM</namePart><affiliation>Department of Neurology, Malabar Institute of Medical Sciences, Calicut, India</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Pramod K.</namePart><namePart type="family">Pal</namePart><namePart type="termsOfAddress">DM</namePart><affiliation>Department of Neurology, National Institute of Mental Health & Neurosciences, Bangalore, India</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Yasha</namePart><namePart type="family">Chickabasavaiah</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Department of Neuropathology, National Institute of Mental Health & Neurosciences, Bangalore, India</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Susarla K.</namePart><namePart type="family">Shankar</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Department of Neuropathology, National Institute of Mental Health & Neurosciences, Bangalore, India</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Srikanth S.</namePart><namePart type="family">Govindappa</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Department of Neuroradiology, National Institute of Mental Health & Neurosciences, Bangalore, India</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Parthasarthy</namePart><namePart type="family">Satishchandra</namePart><namePart type="termsOfAddress">DM</namePart><affiliation>Department of Neurology, National Institute of Mental Health & Neurosciences, Bangalore, India</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Uday B.</namePart><namePart type="family">Muthane</namePart><namePart type="termsOfAddress">DM</namePart><affiliation>Department of Neurology, National Institute of Mental Health & Neurosciences, Bangalore, India</affiliation><description>Correspondence: Department of Neurology, National Institute of Mental Health & Neurosciences, Bangalore 560 029, India</description><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre authority="originalCategForm">article</genre><originInfo><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><place><placeTerm type="text">Hoboken</placeTerm></place><dateIssued encoding="w3cdtf">2007-10-15</dateIssued><dateCaptured encoding="w3cdtf">2007-03-07</dateCaptured><dateValid encoding="w3cdtf">2007-05-23</dateValid><copyrightDate encoding="w3cdtf">2007</copyrightDate></originInfo><language><languageTerm type="code" authority="rfc3066">en</languageTerm><languageTerm type="code" authority="iso639-2b">eng</languageTerm></language><physicalDescription><internetMediaType>text/html</internetMediaType><extent unit="figures">2</extent><extent unit="references">10</extent><extent unit="words">2203</extent></physicalDescription><abstract lang="en">Mercury toxicity causes postural tremors, commonly referred to as “mercurial tremors,” and cerebellar dysfunction. A 23‐year woman, 2 years after injecting herself with elemental mercury developed disabling generalized myoclonus and ataxia. Electrophysiological studies confirmed the myoclonus was probably of cortical origin. Her deficits progressed over 2 years and improved after subcutaneous mercury deposits at the injection site were surgically cleared. Myoclonus of cortical origin has never been described in mercury poisoning. It is important to ask patients presenting with jerks about exposure to elemental mercury even if they have a progressive illness, as it is a potentially reversible condition as in our patient. © 2007 Movement Disorder Society</abstract><subject lang="en"><genre>Keywords</genre><topic>elemental mercury</topic><topic>Cortical myoclonus</topic><topic>mercury poisoning</topic><topic>mercurial tremors</topic><topic>cerebellar ataxia</topic></subject><relatedItem type="host"><titleInfo><title>Movement Disorders</title></titleInfo><titleInfo type="abbreviated"><title>Mov. Disord.</title></titleInfo><note type="content"> This article includes supplementary video clips, available online at http://www.interscience.wiley.com/jpages/0885–3185/suppmat</note><subject><genre>article category</genre><topic>Brief Report</topic></subject><identifier type="ISSN">0885-3185</identifier><identifier type="eISSN">1531-8257</identifier><identifier type="DOI">10.1002/(ISSN)1531-8257</identifier><identifier type="PublisherID">MDS</identifier><part><date>2007</date><detail type="volume"><caption>vol.</caption><number>22</number></detail><detail type="issue"><caption>no.</caption><number>13</number></detail><extent unit="pages"><start>1964</start><end>1968</end><total>5</total></extent></part></relatedItem><identifier type="istex">0E45601FBC11DF2B54421136DDE3555E2132B3E4</identifier><identifier type="DOI">10.1002/mds.21641</identifier><identifier type="ArticleID">MDS21641</identifier><accessCondition type="use and reproduction" contentType="copyright">Copyright © 2007 Movement Disorder Society</accessCondition><recordInfo><recordOrigin>Wiley Subscription Services, Inc., A Wiley Company</recordOrigin><recordContentSource>WILEY</recordContentSource></recordInfo></mods></metadata><serie></serie></istex></record>Pour manipuler ce document sous Unix (Dilib)
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