The international cooperative ataxia rating scale in Machado‐Joseph disease. Comparison with the unified multiple system atrophy rating scale
Identifieur interne : 003115 ( Istex/Corpus ); précédent : 003114; suivant : 003116The international cooperative ataxia rating scale in Machado‐Joseph disease. Comparison with the unified multiple system atrophy rating scale
Auteurs : Anelyssa D'Abreu ; Marcondes Franca Jr. ; Iscia Lopes-Cendes ; Fernando CendesSource :
- Movement Disorders [ 0885-3185 ] ; 2007-10-15.
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Abstract
Our purpose was to evaluate and compare the international cooperative ataxia rating scale (ICARS) and the unified multiple system atrophy rating scale (UMSARS) in patients with Machado‐Joseph disease (MJD). We assessed 52 consecutive subjects with MJD using each scale. Both scales had adequate internal consistency (α > 0.90), except for the oculomotor (OD) subscore (α = 0.08). Patients with dystonia had the highest scores in both scales, and symptoms other than ataxia clearly confounded the total ICARS score. There was a very strong correlation between the ICARS and UMSARS‐II (motor function), and the correlations between the ICARS and UMSARS‐I (r = 0.79) (history) and UMSARS‐IV (r = 0.69) (disability) were also statistically significant. We found no significant changes in scores after a mean interval of 7.7 months, although there was after a mean interval of 13.3 months. We conclude that the total ICARS score is a reliable method for longitudinal evaluation of ataxia in MJD, but a disease specific scale should be developed. © 2007 Movement Disorder Society
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DOI: 10.1002/mds.21735
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We assessed 52 consecutive subjects with MJD using each scale. Both scales had adequate internal consistency (α > 0.90), except for the oculomotor (OD) subscore (α = 0.08). Patients with dystonia had the highest scores in both scales, and symptoms other than ataxia clearly confounded the total ICARS score. There was a very strong correlation between the ICARS and UMSARS‐II (motor function), and the correlations between the ICARS and UMSARS‐I (<i>r</i> = 0.79) (history) and UMSARS‐IV (<i>r</i> = 0.69) (disability) were also statistically significant. We found no significant changes in scores after a mean interval of 7.7 months, although there was after a mean interval of 13.3 months. We conclude that the total ICARS score is a reliable method for longitudinal evaluation of ataxia in MJD, but a disease specific scale should be developed. © 2007 Movement Disorder Society</p></abstract></abstractGroup></contentMeta></header></component></istex:document></istex:metadataXml><!--Version 0.6 générée le 3-12-2015--><mods version="3.6"><titleInfo lang="en"><title>The international cooperative ataxia rating scale in Machado‐Joseph disease. Comparison with the unified multiple system atrophy rating scale</title></titleInfo><titleInfo type="abbreviated" lang="en"><title>ICARS in MJD</title></titleInfo><titleInfo type="alternative" contentType="CDATA" lang="en"><title>The international cooperative ataxia rating scale in Machado‐Joseph disease. 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We assessed 52 consecutive subjects with MJD using each scale. Both scales had adequate internal consistency (α > 0.90), except for the oculomotor (OD) subscore (α = 0.08). Patients with dystonia had the highest scores in both scales, and symptoms other than ataxia clearly confounded the total ICARS score. There was a very strong correlation between the ICARS and UMSARS‐II (motor function), and the correlations between the ICARS and UMSARS‐I (r = 0.79) (history) and UMSARS‐IV (r = 0.69) (disability) were also statistically significant. We found no significant changes in scores after a mean interval of 7.7 months, although there was after a mean interval of 13.3 months. We conclude that the total ICARS score is a reliable method for longitudinal evaluation of ataxia in MJD, but a disease specific scale should be developed. © 2007 Movement Disorder Society</abstract><subject lang="en"><genre>Keywords</genre><topic>ICARS</topic><topic>UMARS</topic><topic>Machado‐Joseph disease</topic><topic>ataxia</topic><topic>scale</topic></subject><relatedItem type="host"><titleInfo><title>Movement Disorders</title></titleInfo><titleInfo type="abbreviated"><title>Mov. Disord.</title></titleInfo><subject><genre>article category</genre><topic>Brief Report</topic></subject><identifier type="ISSN">0885-3185</identifier><identifier type="eISSN">1531-8257</identifier><identifier type="DOI">10.1002/(ISSN)1531-8257</identifier><identifier type="PublisherID">MDS</identifier><part><date>2007</date><detail type="volume"><caption>vol.</caption><number>22</number></detail><detail type="issue"><caption>no.</caption><number>13</number></detail><extent unit="pages"><start>1976</start><end>1979</end><total>4</total></extent></part></relatedItem><identifier type="istex">65406B93E5E20B3B78F3BF3C9E11A70A0CF7E3F3</identifier><identifier type="DOI">10.1002/mds.21735</identifier><identifier type="ArticleID">MDS21735</identifier><accessCondition type="use and reproduction" contentType="copyright">Copyright © 2007 Movement Disorder Society</accessCondition><recordInfo><recordOrigin>Wiley Subscription Services, Inc., A Wiley Company</recordOrigin><recordContentSource>WILEY</recordContentSource></recordInfo></mods></metadata><serie></serie></istex></record>Pour manipuler ce document sous Unix (Dilib)
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|texte= The international cooperative ataxia rating scale in Machado‐Joseph disease. Comparison with the unified multiple system atrophy rating scale
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