Movement Disorders (revue)

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Alpha‐synuclein immunohistochemistry in two cases of co‐occurring idiopathic Parkinson's disease and motor neuron disease

Identifieur interne : 002F69 ( Istex/Corpus ); précédent : 002F68; suivant : 002F70

Alpha‐synuclein immunohistochemistry in two cases of co‐occurring idiopathic Parkinson's disease and motor neuron disease

Auteurs : Kevin J. Klos ; Keith A. Josephs ; Joseph E. Parisi ; Dennis W. Dickson

Source :

RBID : ISTEX:E666596F8731DB503E0C0680FF5F9ABFEB241967

English descriptors

Abstract

We report on two cases of sporadic idiopathic Parkinson's disease with motor neuron disease co‐occurring in the same individuals. Pathological analysis revealed the presence of Lewy bodies in brainstem nuclei and basal forebrain consistent with Lewy body disease (LBD), as well as motor neuron degeneration and argyrophilic grain disease. We compared our two cases to all previously published pathological cases of combined LBD and motor neuron degeneration. © 2005 Movement Disorder Society

Url:
DOI: 10.1002/mds.20604

Links to Exploration step

ISTEX:E666596F8731DB503E0C0680FF5F9ABFEB241967

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<languageTerm type="code" authority="iso639-2b">eng</languageTerm>
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<abstract lang="en">We report on two cases of sporadic idiopathic Parkinson's disease with motor neuron disease co‐occurring in the same individuals. Pathological analysis revealed the presence of Lewy bodies in brainstem nuclei and basal forebrain consistent with Lewy body disease (LBD), as well as motor neuron degeneration and argyrophilic grain disease. We compared our two cases to all previously published pathological cases of combined LBD and motor neuron degeneration. © 2005 Movement Disorder Society</abstract>
<subject lang="en">
<genre>Keywords</genre>
<topic>sporadic idiopathic Parkinson's disease</topic>
<topic>motor neuron disease</topic>
<topic>Lewy bodies</topic>
<topic>argyrophilic grain disease</topic>
</subject>
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<titleInfo>
<title>Movement Disorders</title>
<subTitle>Official Journal of the Movement Disorder Society</subTitle>
</titleInfo>
<titleInfo type="abbreviated">
<title>Mov. Disord.</title>
</titleInfo>
<subject>
<genre>article category</genre>
<topic>Brief Report</topic>
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<identifier type="ISSN">0885-3185</identifier>
<identifier type="eISSN">1531-8257</identifier>
<identifier type="DOI">10.1002/(ISSN)1531-8257</identifier>
<identifier type="PublisherID">MDS</identifier>
<part>
<date>2005</date>
<detail type="volume">
<caption>vol.</caption>
<number>20</number>
</detail>
<detail type="issue">
<caption>no.</caption>
<number>11</number>
</detail>
<extent unit="pages">
<start>1515</start>
<end>1520</end>
<total>6</total>
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</part>
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<identifier type="istex">E666596F8731DB503E0C0680FF5F9ABFEB241967</identifier>
<identifier type="DOI">10.1002/mds.20604</identifier>
<identifier type="ArticleID">MDS20604</identifier>
<accessCondition type="use and reproduction" contentType="copyright">Copyright © 2005 Movement Disorder Society</accessCondition>
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<recordContentSource>WILEY</recordContentSource>
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