Movement Disorders (revue)

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Exposure to well water and pesticides in Parkinson's disease: A case‐control study in the madrid area

Identifieur interne : 002F68 ( Istex/Corpus ); précédent : 002F67; suivant : 002F69

Exposure to well water and pesticides in Parkinson's disease: A case‐control study in the madrid area

Auteurs : Félix Javier Jiménez-Jiménez ; Dolores Mateo ; Santiago Giménez-Roldán

Source :

RBID : ISTEX:2387DE501581F7E4E353C49A349D7C11FC629787

English descriptors

Abstract

Past exposure to well water and pesticides was assessed in 128 unselected Parkinson's disease (PD) patients and 256 age and sex‐matched controls. All were residents in a defined urban area of Madrid, Spain. In keeping with other reports, we found that exposure to well water might be a factor associated with the likelihood of developing PD, though only prolonged exposures of 30 years or longer were significantly different between PD and controls (p < 0.02). In contrast, past exposure to pesticides did not appear to be associated with an increased risk of developing PD. Prolonged well water drinking antedating the development of PD was not associated with early onset of the disease, nor did such cases progress to greater disability. Future casecontrol studies addressing prolonged well water consumption as a risk factor in PD should look for differences in the content of substances other than pesticides in the water as determined by the source of water to which patients may have been specifically exposed.

Url:
DOI: 10.1002/mds.870070209

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ISTEX:2387DE501581F7E4E353C49A349D7C11FC629787

Le document en format XML

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<abstract lang="en">Past exposure to well water and pesticides was assessed in 128 unselected Parkinson's disease (PD) patients and 256 age and sex‐matched controls. All were residents in a defined urban area of Madrid, Spain. In keeping with other reports, we found that exposure to well water might be a factor associated with the likelihood of developing PD, though only prolonged exposures of 30 years or longer were significantly different between PD and controls (p < 0.02). In contrast, past exposure to pesticides did not appear to be associated with an increased risk of developing PD. Prolonged well water drinking antedating the development of PD was not associated with early onset of the disease, nor did such cases progress to greater disability. Future casecontrol studies addressing prolonged well water consumption as a risk factor in PD should look for differences in the content of substances other than pesticides in the water as determined by the source of water to which patients may have been specifically exposed.</abstract>
<subject lang="en">
<genre>Keywords</genre>
<topic>Parkinson's disease</topic>
<topic>Etiology</topic>
<topic>Well water exposure</topic>
<topic>Pesticides</topic>
<topic>Epidemiology</topic>
</subject>
<relatedItem type="host">
<titleInfo>
<title>Movement Disorders</title>
<subTitle>Official Journal of the Movement Disorder Society</subTitle>
</titleInfo>
<titleInfo type="abbreviated">
<title>Mov. Disord.</title>
</titleInfo>
<subject>
<genre>article category</genre>
<topic>Article</topic>
</subject>
<identifier type="ISSN">0885-3185</identifier>
<identifier type="eISSN">1531-8257</identifier>
<identifier type="DOI">10.1002/(ISSN)1531-8257</identifier>
<identifier type="PublisherID">MDS</identifier>
<part>
<date>1992</date>
<detail type="volume">
<caption>vol.</caption>
<number>7</number>
</detail>
<detail type="issue">
<caption>no.</caption>
<number>2</number>
</detail>
<extent unit="pages">
<start>149</start>
<end>152</end>
<total>4</total>
</extent>
</part>
</relatedItem>
<identifier type="istex">2387DE501581F7E4E353C49A349D7C11FC629787</identifier>
<identifier type="DOI">10.1002/mds.870070209</identifier>
<identifier type="ArticleID">MDS870070209</identifier>
<accessCondition type="use and reproduction" contentType="copyright">Copyright © 1992 Movement Disorder Society</accessCondition>
<recordInfo>
<recordOrigin>Wiley Subscription Services, Inc., A Wiley Company</recordOrigin>
<recordContentSource>WILEY</recordContentSource>
</recordInfo>
</mods>
</metadata>
<serie></serie>
</istex>
</record>

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