Neurophysiological investigations in patients with primary writing tremor
Identifieur interne : 002D59 ( Istex/Corpus ); précédent : 002D58; suivant : 002D60Neurophysiological investigations in patients with primary writing tremor
Auteurs : Nicola Modugno ; Yusaku Nakamura ; Sven Bestmann ; Antonio Curra ; Alfredo Berardelli ; John RothwellSource :
- Movement Disorders [ 0885-3185 ] ; 2002-11.
English descriptors
- KwdEn :
Abstract
The pathophysiology of primary writing tremor (PWT) is still unknown: it has been classified as a focal form of essential tremor and as a tremulous form of writer's cramp. We studied cortical and spinal excitability in patients with PWT and compared the results with published data of patients with essential tremor, and writer's cramp. We used electrical stimulation of median and radial nerve to study reciprocal inhibition of forearm antagonist muscles and paired transcranial magnetic stimulation at short and long interstimulus intervals (ISIs) to assess intracortical excitability. Both studies were conducted on patients with PWT and on control subjects. The early (presynaptic) and late (disynaptic) phases of reciprocal inhibition were normal as was intracortical excitability at short and long ISIs. Our study suggests that the pathophysiology of PWT is different from that of writer's cramp and partially also from that of essential tremor. © 2002 Movement Disorder Society
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DOI: 10.1002/mds.10292
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ISTEX:48B0611479C9260A3E8EE59D956BDE52502FEA32Le document en format XML
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We used electrical stimulation of median and radial nerve to study reciprocal inhibition of forearm antagonist muscles and paired transcranial magnetic stimulation at short and long interstimulus intervals (ISIs) to assess intracortical excitability. Both studies were conducted on patients with PWT and on control subjects. The early (presynaptic) and late (disynaptic) phases of reciprocal inhibition were normal as was intracortical excitability at short and long ISIs. Our study suggests that the pathophysiology of PWT is different from that of writer's cramp and partially also from that of essential tremor. © 2002 Movement Disorder Society</p></abstract></abstractGroup></contentMeta></header></component></istex:document></istex:metadataXml><!--Version 0.6 générée le 3-12-2015--><mods version="3.6"><titleInfo lang="en"><title>Neurophysiological investigations in patients with primary writing tremor</title></titleInfo><titleInfo type="abbreviated" lang="en"><title>Pathophysiology of Primary Writing Tremor</title></titleInfo><titleInfo type="alternative" contentType="CDATA" lang="en"><title>Neurophysiological investigations in patients with primary writing tremor</title></titleInfo><name type="personal"><namePart type="given">Nicola</namePart><namePart type="family">Modugno</namePart><namePart type="termsOfAddress">MD, PhD</namePart><affiliation>Dipartimento di Scienze Neurologiche, Universitá di Roma La Sapienza, Roma, and Istituto Neurologico Mediterraneo Neuromed, Pozzilli, Italy</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Yusaku</namePart><namePart type="family">Nakamura</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Dipartimento di Scienze Neurologiche, Universitá di Roma La Sapienza, Roma, and Istituto Neurologico Mediterraneo Neuromed, Pozzilli, Italy</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Sven</namePart><namePart type="family">Bestmann</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Sobell Department of Neurophysiology. The Institute of Neurology, National Hospital for Neurology and Neurosurgery, Queen Square, London, United Kingdom</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Antonio</namePart><namePart type="family">Curra</namePart><namePart type="termsOfAddress">MD, PhD</namePart><affiliation>Dipartimento di Scienze Neurologiche, Universitá di Roma La Sapienza, Roma, and Istituto Neurologico Mediterraneo Neuromed, Pozzilli, Italy</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Alfredo</namePart><namePart type="family">Berardelli</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Dipartimento di Scienze Neurologiche, Universitá di Roma La Sapienza, Roma, and Istituto Neurologico Mediterraneo Neuromed, Pozzilli, Italy</affiliation><description>Correspondence: Dipartimento di Scienze Neurologiche, Universitá di Roma La Sapienza, Viale dell'Universitá 30, Rome, 00185 Italy</description><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">John</namePart><namePart type="family">Rothwell</namePart><namePart type="termsOfAddress">PhD</namePart><affiliation>Sobell Department of Neurophysiology. The Institute of Neurology, National Hospital for Neurology and Neurosurgery, Queen Square, London, United Kingdom</affiliation><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre authority="originalCategForm">article</genre><originInfo><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><place><placeTerm type="text">New York</placeTerm></place><dateIssued encoding="w3cdtf">2002-11</dateIssued><dateCaptured encoding="w3cdtf">2001-10-18</dateCaptured><dateValid encoding="w3cdtf">2002-05-15</dateValid><copyrightDate encoding="w3cdtf">2002</copyrightDate></originInfo><language><languageTerm type="code" authority="rfc3066">en</languageTerm><languageTerm type="code" authority="iso639-2b">eng</languageTerm></language><physicalDescription><internetMediaType>text/html</internetMediaType><extent unit="figures">2</extent><extent unit="tables">1</extent><extent unit="references">20</extent><extent unit="words">2462</extent></physicalDescription><abstract lang="en">The pathophysiology of primary writing tremor (PWT) is still unknown: it has been classified as a focal form of essential tremor and as a tremulous form of writer's cramp. We studied cortical and spinal excitability in patients with PWT and compared the results with published data of patients with essential tremor, and writer's cramp. We used electrical stimulation of median and radial nerve to study reciprocal inhibition of forearm antagonist muscles and paired transcranial magnetic stimulation at short and long interstimulus intervals (ISIs) to assess intracortical excitability. Both studies were conducted on patients with PWT and on control subjects. The early (presynaptic) and late (disynaptic) phases of reciprocal inhibition were normal as was intracortical excitability at short and long ISIs. Our study suggests that the pathophysiology of PWT is different from that of writer's cramp and partially also from that of essential tremor. © 2002 Movement Disorder Society</abstract><subject lang="en"><genre>Keywords</genre><topic>primary writing tremor</topic><topic>writer's cramp</topic><topic>essential tremor</topic><topic>transcranial magnetic stimulation</topic><topic>reciprocal inhibition</topic></subject><relatedItem type="host"><titleInfo><title>Movement Disorders</title><subTitle>Official Journal of the Movement Disorder Society</subTitle></titleInfo><titleInfo type="abbreviated"><title>Mov. Disord.</title></titleInfo><subject><genre>article category</genre><topic>Brief Report</topic></subject><identifier type="ISSN">0885-3185</identifier><identifier type="eISSN">1531-8257</identifier><identifier type="DOI">10.1002/(ISSN)1531-8257</identifier><identifier type="PublisherID">MDS</identifier><part><date>2002</date><detail type="volume"><caption>vol.</caption><number>17</number></detail><detail type="issue"><caption>no.</caption><number>6</number></detail><extent unit="pages"><start>1336</start><end>1340</end><total>5</total></extent></part></relatedItem><identifier type="istex">48B0611479C9260A3E8EE59D956BDE52502FEA32</identifier><identifier type="DOI">10.1002/mds.10292</identifier><identifier type="ArticleID">MDS10292</identifier><accessCondition type="use and reproduction" contentType="copyright">Copyright © 2002 Movement Disorders Society</accessCondition><recordInfo><recordOrigin>Wiley Subscription Services, Inc., A Wiley Company</recordOrigin><recordContentSource>WILEY</recordContentSource></recordInfo></mods></metadata><serie></serie></istex></record>Pour manipuler ce document sous Unix (Dilib)
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