Neurophysiological investigations in patients with primary writing tremor
Identifieur interne : 002D59 ( Istex/Corpus ); précédent : 002D58; suivant : 002D60Neurophysiological investigations in patients with primary writing tremor
Auteurs : Nicola Modugno ; Yusaku Nakamura ; Sven Bestmann ; Antonio Curra ; Alfredo Berardelli ; John RothwellSource :
- Movement Disorders [ 0885-3185 ] ; 2002-11.
English descriptors
- KwdEn :
Abstract
The pathophysiology of primary writing tremor (PWT) is still unknown: it has been classified as a focal form of essential tremor and as a tremulous form of writer's cramp. We studied cortical and spinal excitability in patients with PWT and compared the results with published data of patients with essential tremor, and writer's cramp. We used electrical stimulation of median and radial nerve to study reciprocal inhibition of forearm antagonist muscles and paired transcranial magnetic stimulation at short and long interstimulus intervals (ISIs) to assess intracortical excitability. Both studies were conducted on patients with PWT and on control subjects. The early (presynaptic) and late (disynaptic) phases of reciprocal inhibition were normal as was intracortical excitability at short and long ISIs. Our study suggests that the pathophysiology of PWT is different from that of writer's cramp and partially also from that of essential tremor. © 2002 Movement Disorder Society
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DOI: 10.1002/mds.10292
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<front><div type="abstract" xml:lang="en">The pathophysiology of primary writing tremor (PWT) is still unknown: it has been classified as a focal form of essential tremor and as a tremulous form of writer's cramp. We studied cortical and spinal excitability in patients with PWT and compared the results with published data of patients with essential tremor, and writer's cramp. We used electrical stimulation of median and radial nerve to study reciprocal inhibition of forearm antagonist muscles and paired transcranial magnetic stimulation at short and long interstimulus intervals (ISIs) to assess intracortical excitability. Both studies were conducted on patients with PWT and on control subjects. The early (presynaptic) and late (disynaptic) phases of reciprocal inhibition were normal as was intracortical excitability at short and long ISIs. Our study suggests that the pathophysiology of PWT is different from that of writer's cramp and partially also from that of essential tremor. © 2002 Movement Disorder Society</div>
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<keywordGroup xml:lang="en" type="author"><keyword xml:id="kwd1">primary writing tremor</keyword>
<keyword xml:id="kwd2">writer's cramp</keyword>
<keyword xml:id="kwd3">essential tremor</keyword>
<keyword xml:id="kwd4">transcranial magnetic stimulation</keyword>
<keyword xml:id="kwd5">reciprocal inhibition</keyword>
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<abstractGroup><abstract type="main" xml:lang="en"><title type="main">Abstract</title>
<p>The pathophysiology of primary writing tremor (PWT) is still unknown: it has been classified as a focal form of essential tremor and as a tremulous form of writer's cramp. We studied cortical and spinal excitability in patients with PWT and compared the results with published data of patients with essential tremor, and writer's cramp. We used electrical stimulation of median and radial nerve to study reciprocal inhibition of forearm antagonist muscles and paired transcranial magnetic stimulation at short and long interstimulus intervals (ISIs) to assess intracortical excitability. Both studies were conducted on patients with PWT and on control subjects. The early (presynaptic) and late (disynaptic) phases of reciprocal inhibition were normal as was intracortical excitability at short and long ISIs. Our study suggests that the pathophysiology of PWT is different from that of writer's cramp and partially also from that of essential tremor. © 2002 Movement Disorder Society</p>
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<!--Version 0.6 générée le 3-12-2015--><mods version="3.6"><titleInfo lang="en"><title>Neurophysiological investigations in patients with primary writing tremor</title>
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<titleInfo type="abbreviated" lang="en"><title>Pathophysiology of Primary Writing Tremor</title>
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<titleInfo type="alternative" contentType="CDATA" lang="en"><title>Neurophysiological investigations in patients with primary writing tremor</title>
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<name type="personal"><namePart type="given">Nicola</namePart>
<namePart type="family">Modugno</namePart>
<namePart type="termsOfAddress">MD, PhD</namePart>
<affiliation>Dipartimento di Scienze Neurologiche, Universitá di Roma La Sapienza, Roma, and Istituto Neurologico Mediterraneo Neuromed, Pozzilli, Italy</affiliation>
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<name type="personal"><namePart type="given">Yusaku</namePart>
<namePart type="family">Nakamura</namePart>
<namePart type="termsOfAddress">MD</namePart>
<affiliation>Dipartimento di Scienze Neurologiche, Universitá di Roma La Sapienza, Roma, and Istituto Neurologico Mediterraneo Neuromed, Pozzilli, Italy</affiliation>
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<name type="personal"><namePart type="given">Sven</namePart>
<namePart type="family">Bestmann</namePart>
<namePart type="termsOfAddress">MD</namePart>
<affiliation>Sobell Department of Neurophysiology. The Institute of Neurology, National Hospital for Neurology and Neurosurgery, Queen Square, London, United Kingdom</affiliation>
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<name type="personal"><namePart type="given">Antonio</namePart>
<namePart type="family">Curra</namePart>
<namePart type="termsOfAddress">MD, PhD</namePart>
<affiliation>Dipartimento di Scienze Neurologiche, Universitá di Roma La Sapienza, Roma, and Istituto Neurologico Mediterraneo Neuromed, Pozzilli, Italy</affiliation>
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<name type="personal"><namePart type="given">Alfredo</namePart>
<namePart type="family">Berardelli</namePart>
<namePart type="termsOfAddress">MD</namePart>
<affiliation>Dipartimento di Scienze Neurologiche, Universitá di Roma La Sapienza, Roma, and Istituto Neurologico Mediterraneo Neuromed, Pozzilli, Italy</affiliation>
<description>Correspondence: Dipartimento di Scienze Neurologiche, Universitá di Roma La Sapienza, Viale dell'Universitá 30, Rome, 00185 Italy</description>
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<name type="personal"><namePart type="given">John</namePart>
<namePart type="family">Rothwell</namePart>
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<affiliation>Sobell Department of Neurophysiology. The Institute of Neurology, National Hospital for Neurology and Neurosurgery, Queen Square, London, United Kingdom</affiliation>
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<dateIssued encoding="w3cdtf">2002-11</dateIssued>
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<abstract lang="en">The pathophysiology of primary writing tremor (PWT) is still unknown: it has been classified as a focal form of essential tremor and as a tremulous form of writer's cramp. We studied cortical and spinal excitability in patients with PWT and compared the results with published data of patients with essential tremor, and writer's cramp. We used electrical stimulation of median and radial nerve to study reciprocal inhibition of forearm antagonist muscles and paired transcranial magnetic stimulation at short and long interstimulus intervals (ISIs) to assess intracortical excitability. Both studies were conducted on patients with PWT and on control subjects. The early (presynaptic) and late (disynaptic) phases of reciprocal inhibition were normal as was intracortical excitability at short and long ISIs. Our study suggests that the pathophysiology of PWT is different from that of writer's cramp and partially also from that of essential tremor. © 2002 Movement Disorder Society</abstract>
<subject lang="en"><genre>Keywords</genre>
<topic>primary writing tremor</topic>
<topic>writer's cramp</topic>
<topic>essential tremor</topic>
<topic>transcranial magnetic stimulation</topic>
<topic>reciprocal inhibition</topic>
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<relatedItem type="host"><titleInfo><title>Movement Disorders</title>
<subTitle>Official Journal of the Movement Disorder Society</subTitle>
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<identifier type="ISSN">0885-3185</identifier>
<identifier type="eISSN">1531-8257</identifier>
<identifier type="DOI">10.1002/(ISSN)1531-8257</identifier>
<identifier type="PublisherID">MDS</identifier>
<part><date>2002</date>
<detail type="volume"><caption>vol.</caption>
<number>17</number>
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<accessCondition type="use and reproduction" contentType="copyright">Copyright © 2002 Movement Disorders Society</accessCondition>
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