Evaluating posterolateral linearization of the putaminal margin with magnetic resonance imaging to diagnose the Parkinson variant of multiple system atrophy
Identifieur interne : 002A71 ( Istex/Corpus ); précédent : 002A70; suivant : 002A72Evaluating posterolateral linearization of the putaminal margin with magnetic resonance imaging to diagnose the Parkinson variant of multiple system atrophy
Auteurs : Shoichi Ito ; Wakako Shirai ; Takamichi HattoriSource :
- Movement Disorders [ 0885-3185 ] ; 2007-03-15.
English descriptors
Abstract
The objective was to develop a simple method for evaluating putaminal atrophy in patients with the Parkinson variant of multiple system atrophy (MSA‐P). We used magnetic resonance imaging to study 9 patients with MSA‐P, 24 patients with cerebellar variants of multiple system atrophy (MSA‐C), 38 patients with Parkinson's disease (PD), and 27 healthy control subjects. Posterolateral linearization of the putaminal margin was semiquantitatively scored and the putaminal area per intracranial area was calculated as the adjusted putaminal area. There was a negative correlation between the linearization scores and adjusted putaminal areas (r = −0.43, P < 0.001), such that the mean adjusted putaminal area in the group without putaminal linearization (0.0148 ± 0.0022) was greater than that of the group with linearization (0.0124 ± 0.0029, P < 0.005). Moreover, the occurrence of putaminal linearization was significantly higher in MSA‐P patients (88.8%) than in MSA‐C (8.3%), PD (7.9%) and healthy subjects (7.4%; P < 0.005). Putaminal linearization was a highly sensitive (0.89) and specific (0.91) measure for differentiating MSA‐P. Our results suggest that evaluating posterolateral putaminal linearization is useful for assessing putaminal atrophy and for differentiating MSA‐P from MSA‐C, PD, and healthy subjects. © 2007 Movement Disorder Society
Url:
DOI: 10.1002/mds.21329
Links to Exploration step
ISTEX:553DCE51003DF733F8D6D7CFE4D07A47BF5B1747Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Evaluating posterolateral linearization of the putaminal margin with magnetic resonance imaging to diagnose the Parkinson variant of multiple system atrophy</title><author><name sortKey="Ito, Shoichi" sort="Ito, Shoichi" uniqKey="Ito S" first="Shoichi" last="Ito">Shoichi Ito</name><affiliation><mods:affiliation>Department of Neurology, Graduate School of Medicine, Chiba University, Chuo‐ku, Chiba, Japan</mods:affiliation></affiliation></author><author><name sortKey="Shirai, Wakako" sort="Shirai, Wakako" uniqKey="Shirai W" first="Wakako" last="Shirai">Wakako Shirai</name><affiliation><mods:affiliation>Department of Neurology, Graduate School of Medicine, Chiba University, Chuo‐ku, Chiba, Japan</mods:affiliation></affiliation></author><author><name sortKey="Hattori, Takamichi" sort="Hattori, Takamichi" uniqKey="Hattori T" first="Takamichi" last="Hattori">Takamichi Hattori</name><affiliation><mods:affiliation>Department of Neurology, Graduate School of Medicine, Chiba University, Chuo‐ku, Chiba, Japan</mods:affiliation></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:553DCE51003DF733F8D6D7CFE4D07A47BF5B1747</idno><date when="2007" year="2007">2007</date><idno type="doi">10.1002/mds.21329</idno><idno type="url">https://api.istex.fr/document/553DCE51003DF733F8D6D7CFE4D07A47BF5B1747/fulltext/pdf</idno><idno type="wicri:Area/Istex/Corpus">002A71</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Evaluating posterolateral linearization of the putaminal margin with magnetic resonance imaging to diagnose the Parkinson variant of multiple system atrophy</title><author><name sortKey="Ito, Shoichi" sort="Ito, Shoichi" uniqKey="Ito S" first="Shoichi" last="Ito">Shoichi Ito</name><affiliation><mods:affiliation>Department of Neurology, Graduate School of Medicine, Chiba University, Chuo‐ku, Chiba, Japan</mods:affiliation></affiliation></author><author><name sortKey="Shirai, Wakako" sort="Shirai, Wakako" uniqKey="Shirai W" first="Wakako" last="Shirai">Wakako Shirai</name><affiliation><mods:affiliation>Department of Neurology, Graduate School of Medicine, Chiba University, Chuo‐ku, Chiba, Japan</mods:affiliation></affiliation></author><author><name sortKey="Hattori, Takamichi" sort="Hattori, Takamichi" uniqKey="Hattori T" first="Takamichi" last="Hattori">Takamichi Hattori</name><affiliation><mods:affiliation>Department of Neurology, Graduate School of Medicine, Chiba University, Chuo‐ku, Chiba, Japan</mods:affiliation></affiliation></author></analytic><monogr></monogr><series><title level="j">Movement Disorders</title><title level="j" type="abbrev">Mov. Disord.</title><idno type="ISSN">0885-3185</idno><idno type="eISSN">1531-8257</idno><imprint><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><pubPlace>Hoboken</pubPlace><date type="published" when="2007-03-15">2007-03-15</date><biblScope unit="vol">22</biblScope><biblScope unit="issue">4</biblScope><biblScope unit="page" from="578">578</biblScope><biblScope unit="page" to="581">581</biblScope></imprint><idno type="ISSN">0885-3185</idno></series><idno type="istex">553DCE51003DF733F8D6D7CFE4D07A47BF5B1747</idno><idno type="DOI">10.1002/mds.21329</idno><idno type="ArticleID">MDS21329</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0885-3185</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>linearization</term><term>multiple system atrophy</term><term>putaminal atrophy</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">The objective was to develop a simple method for evaluating putaminal atrophy in patients with the Parkinson variant of multiple system atrophy (MSA‐P). We used magnetic resonance imaging to study 9 patients with MSA‐P, 24 patients with cerebellar variants of multiple system atrophy (MSA‐C), 38 patients with Parkinson's disease (PD), and 27 healthy control subjects. Posterolateral linearization of the putaminal margin was semiquantitatively scored and the putaminal area per intracranial area was calculated as the adjusted putaminal area. There was a negative correlation between the linearization scores and adjusted putaminal areas (r = −0.43, P < 0.001), such that the mean adjusted putaminal area in the group without putaminal linearization (0.0148 ± 0.0022) was greater than that of the group with linearization (0.0124 ± 0.0029, P < 0.005). Moreover, the occurrence of putaminal linearization was significantly higher in MSA‐P patients (88.8%) than in MSA‐C (8.3%), PD (7.9%) and healthy subjects (7.4%; P < 0.005). Putaminal linearization was a highly sensitive (0.89) and specific (0.91) measure for differentiating MSA‐P. Our results suggest that evaluating posterolateral putaminal linearization is useful for assessing putaminal atrophy and for differentiating MSA‐P from MSA‐C, PD, and healthy subjects. © 2007 Movement Disorder Society</div></front></TEI><istex><corpusName>wiley</corpusName><author><json:item><name>Shoichi Ito MD</name><affiliations><json:string>Department of Neurology, Graduate School of Medicine, Chiba University, Chuo‐ku, Chiba, Japan</json:string></affiliations></json:item><json:item><name>Wakako Shirai MD</name><affiliations><json:string>Department of Neurology, Graduate School of Medicine, Chiba University, Chuo‐ku, Chiba, Japan</json:string></affiliations></json:item><json:item><name>Takamichi Hattori MD</name><affiliations><json:string>Department of Neurology, Graduate School of Medicine, Chiba University, Chuo‐ku, Chiba, Japan</json:string></affiliations></json:item></author><subject><json:item><lang><json:string>eng</json:string></lang><value>putaminal atrophy</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>linearization</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>multiple system atrophy</value></json:item></subject><language><json:string>eng</json:string></language><abstract>The objective was to develop a simple method for evaluating putaminal atrophy in patients with the Parkinson variant of multiple system atrophy (MSA‐P). We used magnetic resonance imaging to study 9 patients with MSA‐P, 24 patients with cerebellar variants of multiple system atrophy (MSA‐C), 38 patients with Parkinson's disease (PD), and 27 healthy control subjects. Posterolateral linearization of the putaminal margin was semiquantitatively scored and the putaminal area per intracranial area was calculated as the adjusted putaminal area. There was a negative correlation between the linearization scores and adjusted putaminal areas (r = −0.43, P > 0.001), such that the mean adjusted putaminal area in the group without putaminal linearization (0.0148 ± 0.0022) was greater than that of the group with linearization (0.0124 ± 0.0029, P > 0.005). Moreover, the occurrence of putaminal linearization was significantly higher in MSA‐P patients (88.8%) than in MSA‐C (8.3%), PD (7.9%) and healthy subjects (7.4%; P > 0.005). Putaminal linearization was a highly sensitive (0.89) and specific (0.91) measure for differentiating MSA‐P. Our results suggest that evaluating posterolateral putaminal linearization is useful for assessing putaminal atrophy and for differentiating MSA‐P from MSA‐C, PD, and healthy subjects. © 2007 Movement Disorder Society</abstract><qualityIndicators><score>4.738</score><pdfVersion>1.3</pdfVersion><pdfPageSize>594 x 792 pts</pdfPageSize><refBibsNative>true</refBibsNative><abstractCharCount>1354</abstractCharCount><pdfWordCount>2374</pdfWordCount><pdfCharCount>15657</pdfCharCount><pdfPageCount>4</pdfPageCount><abstractWordCount>197</abstractWordCount></qualityIndicators><title>Evaluating posterolateral linearization of the putaminal margin with magnetic resonance imaging to diagnose the Parkinson variant of multiple system atrophy</title><genre><json:string>Serial article</json:string></genre><host><volume>22</volume><pages><total>4</total><last>581</last><first>578</first></pages><issn><json:string>0885-3185</json:string></issn><issue>4</issue><subject><json:item><value>Brief Report</value></json:item></subject><genre></genre><language><json:string>unknown</json:string></language><title>Movement Disorders</title><doi><json:string>10.1002/(ISSN)1531-8257</json:string></doi></host><publicationDate>2007</publicationDate><copyrightDate>2007</copyrightDate><doi><json:string>10.1002/mds.21329</json:string></doi><id>553DCE51003DF733F8D6D7CFE4D07A47BF5B1747</id><fulltext><json:item><original>true</original><mimetype>application/pdf</mimetype><extension>pdf</extension><uri>https://api.istex.fr/document/553DCE51003DF733F8D6D7CFE4D07A47BF5B1747/fulltext/pdf</uri></json:item><json:item><original>false</original><mimetype>application/zip</mimetype><extension>zip</extension><uri>https://api.istex.fr/document/553DCE51003DF733F8D6D7CFE4D07A47BF5B1747/fulltext/zip</uri></json:item><istex:fulltextTEI uri="https://api.istex.fr/document/553DCE51003DF733F8D6D7CFE4D07A47BF5B1747/fulltext/tei"><teiHeader type="text"><fileDesc><titleStmt><title level="a" type="main" xml:lang="en">Evaluating posterolateral linearization of the putaminal margin with magnetic resonance imaging to diagnose the Parkinson variant of multiple system atrophy</title></titleStmt><publicationStmt><authority>ISTEX</authority><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><pubPlace>Hoboken</pubPlace><availability><p>Wiley Subscription Services, Inc., A Wiley Company</p></availability><date>2007</date></publicationStmt><sourceDesc><biblStruct type="inbook"><analytic><title level="a" type="main" xml:lang="en">Evaluating posterolateral linearization of the putaminal margin with magnetic resonance imaging to diagnose the Parkinson variant of multiple system atrophy</title><author><persName><forename type="first">Shoichi</forename><surname>Ito</surname><roleName type="degree">MD</roleName></persName><note type="correspondence"><p>Correspondence: Department of Neurology, Graduate School of Medicine, Chiba University, 1–8‐1 Inohana, Chuo‐ku, Chiba, 260‐8670, Japan</p></note><affiliation>Department of Neurology, Graduate School of Medicine, Chiba University, Chuo‐ku, Chiba, Japan</affiliation></author><author><persName><forename type="first">Wakako</forename><surname>Shirai</surname><roleName type="degree">MD</roleName></persName><affiliation>Department of Neurology, Graduate School of Medicine, Chiba University, Chuo‐ku, Chiba, Japan</affiliation></author><author><persName><forename type="first">Takamichi</forename><surname>Hattori</surname><roleName type="degree">MD</roleName></persName><affiliation>Department of Neurology, Graduate School of Medicine, Chiba University, Chuo‐ku, Chiba, Japan</affiliation></author></analytic><monogr><title level="j">Movement Disorders</title><title level="j" type="abbrev">Mov. Disord.</title><idno type="pISSN">0885-3185</idno><idno type="eISSN">1531-8257</idno><idno type="DOI">10.1002/(ISSN)1531-8257</idno><imprint><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><pubPlace>Hoboken</pubPlace><date type="published" when="2007-03-15"></date><biblScope unit="vol">22</biblScope><biblScope unit="issue">4</biblScope><biblScope unit="page" from="578">578</biblScope><biblScope unit="page" to="581">581</biblScope></imprint></monogr><idno type="istex">553DCE51003DF733F8D6D7CFE4D07A47BF5B1747</idno><idno type="DOI">10.1002/mds.21329</idno><idno type="ArticleID">MDS21329</idno></biblStruct></sourceDesc></fileDesc><profileDesc><creation><date>2007</date></creation><langUsage><language ident="en">en</language></langUsage><abstract xml:lang="en"><p>The objective was to develop a simple method for evaluating putaminal atrophy in patients with the Parkinson variant of multiple system atrophy (MSA‐P). We used magnetic resonance imaging to study 9 patients with MSA‐P, 24 patients with cerebellar variants of multiple system atrophy (MSA‐C), 38 patients with Parkinson's disease (PD), and 27 healthy control subjects. Posterolateral linearization of the putaminal margin was semiquantitatively scored and the putaminal area per intracranial area was calculated as the adjusted putaminal area. There was a negative correlation between the linearization scores and adjusted putaminal areas (r = −0.43, P < 0.001), such that the mean adjusted putaminal area in the group without putaminal linearization (0.0148 ± 0.0022) was greater than that of the group with linearization (0.0124 ± 0.0029, P < 0.005). Moreover, the occurrence of putaminal linearization was significantly higher in MSA‐P patients (88.8%) than in MSA‐C (8.3%), PD (7.9%) and healthy subjects (7.4%; P < 0.005). Putaminal linearization was a highly sensitive (0.89) and specific (0.91) measure for differentiating MSA‐P. Our results suggest that evaluating posterolateral putaminal linearization is useful for assessing putaminal atrophy and for differentiating MSA‐P from MSA‐C, PD, and healthy subjects. © 2007 Movement Disorder Society</p></abstract><textClass xml:lang="en"><keywords scheme="keyword"><list><head>Keywords</head><item><term>putaminal atrophy</term></item><item><term>linearization</term></item><item><term>multiple system atrophy</term></item></list></keywords></textClass><textClass><keywords scheme="Journal Subject"><list><head>Article category</head><item><term>Brief Report</term></item></list></keywords></textClass></profileDesc><revisionDesc><change when="2006-09-27">Received</change><change when="2006-10-23">Registration</change><change when="2007-03-15">Published</change></revisionDesc></teiHeader></istex:fulltextTEI><json:item><original>false</original><mimetype>text/plain</mimetype><extension>txt</extension><uri>https://api.istex.fr/document/553DCE51003DF733F8D6D7CFE4D07A47BF5B1747/fulltext/txt</uri></json:item></fulltext><metadata><istex:metadataXml wicri:clean="Wiley, elements deleted: body"><istex:xmlDeclaration>version="1.0" encoding="UTF-8" standalone="yes"</istex:xmlDeclaration><istex:document><component version="2.0" type="serialArticle" xml:lang="en"><header><publicationMeta level="product"><publisherInfo><publisherName>Wiley Subscription Services, Inc., A Wiley Company</publisherName><publisherLoc>Hoboken</publisherLoc></publisherInfo><doi registered="yes">10.1002/(ISSN)1531-8257</doi><issn type="print">0885-3185</issn><issn type="electronic">1531-8257</issn><idGroup><id type="product" value="MDS"></id></idGroup><titleGroup><title type="main" xml:lang="en" sort="MOVEMENT DISORDERS">Movement Disorders</title><title type="short">Mov. Disord.</title></titleGroup></publicationMeta><publicationMeta level="part" position="40"><doi origin="wiley" registered="yes">10.1002/mds.v22:4</doi><numberingGroup><numbering type="journalVolume" number="22">22</numbering><numbering type="journalIssue">4</numbering></numberingGroup><coverDate startDate="2007-03-15">15 March 2007</coverDate></publicationMeta><publicationMeta level="unit" type="article" position="260" status="forIssue"><doi origin="wiley" registered="yes">10.1002/mds.21329</doi><idGroup><id type="unit" value="MDS21329"></id></idGroup><countGroup><count type="pageTotal" number="4"></count></countGroup><titleGroup><title type="articleCategory">Brief Report</title><title type="tocHeading1">Brief Reports</title></titleGroup><copyright ownership="thirdParty">Copyright © 2007 Movement Disorder Society</copyright><eventGroup><event type="manuscriptReceived" date="2006-09-27"></event><event type="manuscriptAccepted" date="2006-10-23"></event><event type="firstOnline" date="2007-01-26"></event><event type="publishedOnlineFinalForm" date="2007-03-27"></event><event type="publishedOnlineAcceptedOrEarlyUnpaginated" date="2007-01-26"></event><event type="xmlConverted" agent="Converter:JWSART34_TO_WML3G version:2.4.7 mode:FullText source:FullText result:FullText" date="2011-02-24"></event><event type="xmlConverted" agent="Converter:WILEY_ML3G_TO_WILEY_ML3GV2 version:3.8.8" date="2014-02-02"></event><event type="xmlConverted" agent="Converter:WML3G_To_WML3G version:4.1.7 mode:FullText,remove_FC" date="2014-10-31"></event></eventGroup><numberingGroup><numbering type="pageFirst">578</numbering><numbering type="pageLast">581</numbering></numberingGroup><correspondenceTo>Department of Neurology, Graduate School of Medicine, Chiba University, 1–8‐1 Inohana, Chuo‐ku, Chiba, 260‐8670, Japan</correspondenceTo><linkGroup><link type="toTypesetVersion" href="file:MDS.MDS21329.pdf"></link></linkGroup></publicationMeta><contentMeta><countGroup><count type="figureTotal" number="1"></count><count type="tableTotal" number="1"></count><count type="referenceTotal" number="16"></count><count type="wordTotal" number="2224"></count></countGroup><titleGroup><title type="main" xml:lang="en">Evaluating posterolateral linearization of the putaminal margin with magnetic resonance imaging to diagnose the Parkinson variant of multiple system atrophy</title><title type="short" xml:lang="en">Putaminal Atrophy</title></titleGroup><creators><creator xml:id="au1" creatorRole="author" affiliationRef="#af1" corresponding="yes"><personName><givenNames>Shoichi</givenNames><familyName>Ito</familyName><degrees>MD</degrees></personName><contactDetails><email normalForm="sito@faculty.chiba-u.jp">sito@faculty.chiba‐u.jp</email></contactDetails></creator><creator xml:id="au2" creatorRole="author" affiliationRef="#af1"><personName><givenNames>Wakako</givenNames><familyName>Shirai</familyName><degrees>MD</degrees></personName></creator><creator xml:id="au3" creatorRole="author" affiliationRef="#af1"><personName><givenNames>Takamichi</givenNames><familyName>Hattori</familyName><degrees>MD</degrees></personName></creator></creators><affiliationGroup><affiliation xml:id="af1" countryCode="JP" type="organization"><unparsedAffiliation>Department of Neurology, Graduate School of Medicine, Chiba University, Chuo‐ku, Chiba, Japan</unparsedAffiliation></affiliation></affiliationGroup><keywordGroup xml:lang="en" type="author"><keyword xml:id="kwd1">putaminal atrophy</keyword><keyword xml:id="kwd2">linearization</keyword><keyword xml:id="kwd3">multiple system atrophy</keyword></keywordGroup><abstractGroup><abstract type="main" xml:lang="en"><title type="main">Abstract</title><p>The objective was to develop a simple method for evaluating putaminal atrophy in patients with the Parkinson variant of multiple system atrophy (MSA‐P). We used magnetic resonance imaging to study 9 patients with MSA‐P, 24 patients with cerebellar variants of multiple system atrophy (MSA‐C), 38 patients with Parkinson's disease (PD), and 27 healthy control subjects. Posterolateral linearization of the putaminal margin was semiquantitatively scored and the putaminal area per intracranial area was calculated as the adjusted putaminal area. There was a negative correlation between the linearization scores and adjusted putaminal areas (r = −0.43, <i>P</i> < 0.001), such that the mean adjusted putaminal area in the group without putaminal linearization (0.0148 ± 0.0022) was greater than that of the group with linearization (0.0124 ± 0.0029, <i>P</i> < 0.005). Moreover, the occurrence of putaminal linearization was significantly higher in MSA‐P patients (88.8%) than in MSA‐C (8.3%), PD (7.9%) and healthy subjects (7.4%; <i>P</i> < 0.005). Putaminal linearization was a highly sensitive (0.89) and specific (0.91) measure for differentiating MSA‐P. Our results suggest that evaluating posterolateral putaminal linearization is useful for assessing putaminal atrophy and for differentiating MSA‐P from MSA‐C, PD, and healthy subjects. © 2007 Movement Disorder Society</p></abstract></abstractGroup></contentMeta></header></component></istex:document></istex:metadataXml><!--Version 0.6 générée le 3-12-2015--><mods version="3.6"><titleInfo lang="en"><title>Evaluating posterolateral linearization of the putaminal margin with magnetic resonance imaging to diagnose the Parkinson variant of multiple system atrophy</title></titleInfo><titleInfo type="abbreviated" lang="en"><title>Putaminal Atrophy</title></titleInfo><titleInfo type="alternative" contentType="CDATA" lang="en"><title>Evaluating posterolateral linearization of the putaminal margin with magnetic resonance imaging to diagnose the Parkinson variant of multiple system atrophy</title></titleInfo><name type="personal"><namePart type="given">Shoichi</namePart><namePart type="family">Ito</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Department of Neurology, Graduate School of Medicine, Chiba University, Chuo‐ku, Chiba, Japan</affiliation><description>Correspondence: Department of Neurology, Graduate School of Medicine, Chiba University, 1–8‐1 Inohana, Chuo‐ku, Chiba, 260‐8670, Japan</description><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Wakako</namePart><namePart type="family">Shirai</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Department of Neurology, Graduate School of Medicine, Chiba University, Chuo‐ku, Chiba, Japan</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Takamichi</namePart><namePart type="family">Hattori</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Department of Neurology, Graduate School of Medicine, Chiba University, Chuo‐ku, Chiba, Japan</affiliation><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre authority="originalCategForm">article</genre><originInfo><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><place><placeTerm type="text">Hoboken</placeTerm></place><dateIssued encoding="w3cdtf">2007-03-15</dateIssued><dateCaptured encoding="w3cdtf">2006-09-27</dateCaptured><dateValid encoding="w3cdtf">2006-10-23</dateValid><copyrightDate encoding="w3cdtf">2007</copyrightDate></originInfo><language><languageTerm type="code" authority="rfc3066">en</languageTerm><languageTerm type="code" authority="iso639-2b">eng</languageTerm></language><physicalDescription><internetMediaType>text/html</internetMediaType><extent unit="figures">1</extent><extent unit="tables">1</extent><extent unit="references">16</extent><extent unit="words">2224</extent></physicalDescription><abstract lang="en">The objective was to develop a simple method for evaluating putaminal atrophy in patients with the Parkinson variant of multiple system atrophy (MSA‐P). We used magnetic resonance imaging to study 9 patients with MSA‐P, 24 patients with cerebellar variants of multiple system atrophy (MSA‐C), 38 patients with Parkinson's disease (PD), and 27 healthy control subjects. Posterolateral linearization of the putaminal margin was semiquantitatively scored and the putaminal area per intracranial area was calculated as the adjusted putaminal area. There was a negative correlation between the linearization scores and adjusted putaminal areas (r = −0.43, P < 0.001), such that the mean adjusted putaminal area in the group without putaminal linearization (0.0148 ± 0.0022) was greater than that of the group with linearization (0.0124 ± 0.0029, P < 0.005). Moreover, the occurrence of putaminal linearization was significantly higher in MSA‐P patients (88.8%) than in MSA‐C (8.3%), PD (7.9%) and healthy subjects (7.4%; P < 0.005). Putaminal linearization was a highly sensitive (0.89) and specific (0.91) measure for differentiating MSA‐P. Our results suggest that evaluating posterolateral putaminal linearization is useful for assessing putaminal atrophy and for differentiating MSA‐P from MSA‐C, PD, and healthy subjects. © 2007 Movement Disorder Society</abstract><subject lang="en"><genre>Keywords</genre><topic>putaminal atrophy</topic><topic>linearization</topic><topic>multiple system atrophy</topic></subject><relatedItem type="host"><titleInfo><title>Movement Disorders</title></titleInfo><titleInfo type="abbreviated"><title>Mov. Disord.</title></titleInfo><subject><genre>article category</genre><topic>Brief Report</topic></subject><identifier type="ISSN">0885-3185</identifier><identifier type="eISSN">1531-8257</identifier><identifier type="DOI">10.1002/(ISSN)1531-8257</identifier><identifier type="PublisherID">MDS</identifier><part><date>2007</date><detail type="volume"><caption>vol.</caption><number>22</number></detail><detail type="issue"><caption>no.</caption><number>4</number></detail><extent unit="pages"><start>578</start><end>581</end><total>4</total></extent></part></relatedItem><identifier type="istex">553DCE51003DF733F8D6D7CFE4D07A47BF5B1747</identifier><identifier type="DOI">10.1002/mds.21329</identifier><identifier type="ArticleID">MDS21329</identifier><accessCondition type="use and reproduction" contentType="copyright">Copyright © 2007 Movement Disorder Society</accessCondition><recordInfo><recordOrigin>Wiley Subscription Services, Inc., A Wiley Company</recordOrigin><recordContentSource>WILEY</recordContentSource></recordInfo></mods></metadata><serie></serie></istex></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Santé/explor/MovDisordV3/Data/Istex/Corpus
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 002A71 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Istex/Corpus/biblio.hfd -nk 002A71 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Santé
|area= MovDisordV3
|flux= Istex
|étape= Corpus
|type= RBID
|clé= ISTEX:553DCE51003DF733F8D6D7CFE4D07A47BF5B1747
|texte= Evaluating posterolateral linearization of the putaminal margin with magnetic resonance imaging to diagnose the Parkinson variant of multiple system atrophy
}}
| This area was generated with Dilib version V0.6.23. |  |