Questionnaire‐based assessment of pelvic organ dysfunction in multiple system atrophy
Identifieur interne : 001E54 ( Istex/Corpus ); précédent : 001E53; suivant : 001E55Questionnaire‐based assessment of pelvic organ dysfunction in multiple system atrophy
Auteurs : Tatsuya Yamamoto ; Ryuji Sakakibara ; Tomoyuki Uchiyama ; Zhi Liu ; Takashi Ito ; Yusuke Awa ; Tomonori Yamanishi ; Takamichi HattoriSource :
- Movement Disorders [ 0885-3185 ] ; 2009-05-15.
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Abstract
Multiple system atrophy (MSA) is a neurodegenerative disease characterized clinically by any combination of autonomic, cerebellar, and extrapyramidal symptoms. Autonomic symptoms are usually severe, and urinary symptoms are one of the cardinal features of MSA. Bowel dysfunction and sexual dysfunction are also common in MSA. Quality of life (QOL) in patients with MSA is severely impaired by the presence of pelvic organ dysfunction. Therefore, we aimed to examine the prevalence of pelvic organ dysfunction in patients with MSA. We recruited 256 patients with MSA seen at our neurology clinic. The mean age was 62 years. The control group comprised 158 individuals, and the mean age was 52 years. We administered a questionnaire on pelvic organ dysfunction to the MSA and control groups. The questionnaire had sections focusing on the bladder, bowel, and sexual function. Dysfunction, as described in the responses, was evaluated as normal, mild (>once a month), moderate (>once a week), or severe (>once a day). The Mann‐Whitney's U‐test was used for statistical analysis. When compared with the control group, the prevalence of pelvic organ dysfunction in the MSA group was significantly higher for urinary storage and voiding dysfunction, bowel dysfunction, and sexual dysfunction. QOL in the MSA group was therefore significantly impaired because of urinary dysfunction (70%, 76%), bowel dysfunction (40% of the men), and sexual dysfunction (26%, 45%). Pelvic organ dysfunction is common in MSA, and QOL is severely impaired in patients with MSA. © 2009 Movement Disorder Society
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DOI: 10.1002/mds.22332
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ISTEX:798CC1AD377204E2370ACDAAC8A18B9DD81A22FDLe document en format XML
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Tochigi, Japan</mods:affiliation></affiliation></author><author><name sortKey="Hattori, Takamichi" sort="Hattori, Takamichi" uniqKey="Hattori T" first="Takamichi" last="Hattori">Takamichi Hattori</name><affiliation><mods:affiliation>Department of Neurology, Chiba University, Chiba, Japan</mods:affiliation></affiliation></author></analytic><monogr></monogr><series><title level="j">Movement Disorders</title><title level="j" type="abbrev">Mov. 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Autonomic symptoms are usually severe, and urinary symptoms are one of the cardinal features of MSA. Bowel dysfunction and sexual dysfunction are also common in MSA. Quality of life (QOL) in patients with MSA is severely impaired by the presence of pelvic organ dysfunction. Therefore, we aimed to examine the prevalence of pelvic organ dysfunction in patients with MSA. We recruited 256 patients with MSA seen at our neurology clinic. The mean age was 62 years. The control group comprised 158 individuals, and the mean age was 52 years. We administered a questionnaire on pelvic organ dysfunction to the MSA and control groups. The questionnaire had sections focusing on the bladder, bowel, and sexual function. Dysfunction, as described in the responses, was evaluated as normal, mild (>once a month), moderate (>once a week), or severe (>once a day). The Mann‐Whitney's U‐test was used for statistical analysis. When compared with the control group, the prevalence of pelvic organ dysfunction in the MSA group was significantly higher for urinary storage and voiding dysfunction, bowel dysfunction, and sexual dysfunction. QOL in the MSA group was therefore significantly impaired because of urinary dysfunction (70%, 76%), bowel dysfunction (40% of the men), and sexual dysfunction (26%, 45%). Pelvic organ dysfunction is common in MSA, and QOL is severely impaired in patients with MSA. © 2009 Movement Disorder Society</div></front></TEI><istex><corpusName>wiley</corpusName><author><json:item><name>Tatsuya Yamamoto MD</name><affiliations><json:string>Department of Neurology, Chiba University, Chiba, Japan</json:string></affiliations></json:item><json:item><name>Ryuji Sakakibara MD</name><affiliations><json:string>Department of Neurology, Chiba University, Chiba, Japan</json:string><json:string>Neurology Division, Department of Internal Medicine, Sakura Medical Center, Toho University, Sakura, Japan</json:string></affiliations></json:item><json:item><name>Tomoyuki Uchiyama MD</name><affiliations><json:string>Department of Neurology, Chiba University, Chiba, Japan</json:string></affiliations></json:item><json:item><name>Zhi Liu MD</name><affiliations><json:string>Department of Neurology, Chiba University, Chiba, Japan</json:string></affiliations></json:item><json:item><name>Takashi Ito MD</name><affiliations><json:string>Department of Neurology, Chiba University, Chiba, Japan</json:string></affiliations></json:item><json:item><name>Yusuke Awa MD</name><affiliations><json:string>Department of Urology, Chiba University, Chiba, Japan</json:string></affiliations></json:item><json:item><name>Tomonori Yamanishi MD</name><affiliations><json:string>Department of Urology, Dokkyo Medical College, Tochigi, Japan</json:string></affiliations></json:item><json:item><name>Takamichi Hattori MD</name><affiliations><json:string>Department of Neurology, Chiba University, Chiba, Japan</json:string></affiliations></json:item></author><subject><json:item><lang><json:string>eng</json:string></lang><value>multiple system atrophy</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>autonomic dysfunction</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>pelvic organ dysfunction</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>urinary dysfunction</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>quality of life</value></json:item></subject><language><json:string>eng</json:string></language><abstract>Multiple system atrophy (MSA) is a neurodegenerative disease characterized clinically by any combination of autonomic, cerebellar, and extrapyramidal symptoms. Autonomic symptoms are usually severe, and urinary symptoms are one of the cardinal features of MSA. Bowel dysfunction and sexual dysfunction are also common in MSA. Quality of life (QOL) in patients with MSA is severely impaired by the presence of pelvic organ dysfunction. Therefore, we aimed to examine the prevalence of pelvic organ dysfunction in patients with MSA. We recruited 256 patients with MSA seen at our neurology clinic. The mean age was 62 years. The control group comprised 158 individuals, and the mean age was 52 years. We administered a questionnaire on pelvic organ dysfunction to the MSA and control groups. The questionnaire had sections focusing on the bladder, bowel, and sexual function. Dysfunction, as described in the responses, was evaluated as normal, mild (>once a month), moderate (>once a week), or severe (>once a day). The Mann‐Whitney's U‐test was used for statistical analysis. When compared with the control group, the prevalence of pelvic organ dysfunction in the MSA group was significantly higher for urinary storage and voiding dysfunction, bowel dysfunction, and sexual dysfunction. QOL in the MSA group was therefore significantly impaired because of urinary dysfunction (70%, 76%), bowel dysfunction (40% of the men), and sexual dysfunction (26%, 45%). 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When compared with the control group, the prevalence of pelvic organ dysfunction in the MSA group was significantly higher for urinary storage and voiding dysfunction, bowel dysfunction, and sexual dysfunction. QOL in the MSA group was therefore significantly impaired because of urinary dysfunction (70%, 76%), bowel dysfunction (40% of the men), and sexual dysfunction (26%, 45%). 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affiliationRef="#af1"><personName><givenNames>Takamichi</givenNames><familyName>Hattori</familyName><degrees>MD</degrees></personName></creator></creators><affiliationGroup><affiliation xml:id="af1" countryCode="JP" type="organization"><unparsedAffiliation>Department of Neurology, Chiba University, Chiba, Japan</unparsedAffiliation></affiliation><affiliation xml:id="af2" countryCode="JP" type="organization"><unparsedAffiliation>Neurology Division, Department of Internal Medicine, Sakura Medical Center, Toho University, Sakura, Japan</unparsedAffiliation></affiliation><affiliation xml:id="af3" countryCode="JP" type="organization"><unparsedAffiliation>Department of Urology, Chiba University, Chiba, Japan</unparsedAffiliation></affiliation><affiliation xml:id="af4" countryCode="JP" type="organization"><unparsedAffiliation>Department of Urology, Dokkyo Medical College, Tochigi, Japan</unparsedAffiliation></affiliation></affiliationGroup><keywordGroup xml:lang="en" type="author"><keyword xml:id="kwd1">multiple system atrophy</keyword><keyword xml:id="kwd2">autonomic dysfunction</keyword><keyword xml:id="kwd3">pelvic organ dysfunction</keyword><keyword xml:id="kwd4">urinary dysfunction</keyword><keyword xml:id="kwd5">quality of life</keyword></keywordGroup><abstractGroup><abstract type="main" xml:lang="en"><title type="main">Abstract</title><p>Multiple system atrophy (MSA) is a neurodegenerative disease characterized clinically by any combination of autonomic, cerebellar, and extrapyramidal symptoms. Autonomic symptoms are usually severe, and urinary symptoms are one of the cardinal features of MSA. Bowel dysfunction and sexual dysfunction are also common in MSA. Quality of life (QOL) in patients with MSA is severely impaired by the presence of pelvic organ dysfunction. Therefore, we aimed to examine the prevalence of pelvic organ dysfunction in patients with MSA. We recruited 256 patients with MSA seen at our neurology clinic. The mean age was 62 years. The control group comprised 158 individuals, and the mean age was 52 years. We administered a questionnaire on pelvic organ dysfunction to the MSA and control groups. The questionnaire had sections focusing on the bladder, bowel, and sexual function. Dysfunction, as described in the responses, was evaluated as normal, mild (>once a month), moderate (>once a week), or severe (>once a day). The Mann‐Whitney's U‐test was used for statistical analysis. When compared with the control group, the prevalence of pelvic organ dysfunction in the MSA group was significantly higher for urinary storage and voiding dysfunction, bowel dysfunction, and sexual dysfunction. QOL in the MSA group was therefore significantly impaired because of urinary dysfunction (70%, 76%), bowel dysfunction (40% of the men), and sexual dysfunction (26%, 45%). Pelvic organ dysfunction is common in MSA, and QOL is severely impaired in patients with MSA. © 2009 Movement Disorder Society</p></abstract></abstractGroup></contentMeta><noteGroup><note xml:id="fn1"><p>Potential conflict of interest: None reported.</p></note></noteGroup></header></component></istex:document></istex:metadataXml><!--Version 0.6 générée le 4-12-2015--><mods version="3.6"><titleInfo lang="en"><title>Questionnaire‐based assessment of pelvic organ dysfunction in multiple system atrophy</title></titleInfo><titleInfo type="abbreviated" lang="en"><title>Pelvic Organ Dysfunction in MSA</title></titleInfo><titleInfo type="alternative" contentType="CDATA" lang="en"><title>Questionnaire‐based assessment of pelvic organ dysfunction in multiple system atrophy</title></titleInfo><name type="personal"><namePart type="given">Tatsuya</namePart><namePart type="family">Yamamoto</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Department of Neurology, Chiba University, Chiba, Japan</affiliation><description>Correspondence: Department of Neurology, Chiba University, 1‐8‐1 Inohana Chuo‐ku, Chiba, 260‐8670, Japan===</description><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Ryuji</namePart><namePart type="family">Sakakibara</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Department of Neurology, Chiba University, Chiba, Japan</affiliation><affiliation>Neurology Division, Department of Internal Medicine, Sakura Medical Center, Toho University, Sakura, Japan</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Tomoyuki</namePart><namePart type="family">Uchiyama</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Department of Neurology, Chiba University, Chiba, Japan</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Zhi</namePart><namePart type="family">Liu</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Department of Neurology, Chiba University, Chiba, Japan</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Takashi</namePart><namePart type="family">Ito</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Department of Neurology, Chiba University, Chiba, Japan</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Yusuke</namePart><namePart type="family">Awa</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Department of Urology, Chiba University, Chiba, Japan</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Tomonori</namePart><namePart type="family">Yamanishi</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Department of Urology, Dokkyo Medical College, Tochigi, Japan</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Takamichi</namePart><namePart type="family">Hattori</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Department of Neurology, Chiba University, Chiba, Japan</affiliation><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre authority="originalCategForm">article</genre><originInfo><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><place><placeTerm type="text">Hoboken</placeTerm></place><dateIssued encoding="w3cdtf">2009-05-15</dateIssued><dateCaptured encoding="w3cdtf">2007-12-24</dateCaptured><dateValid encoding="w3cdtf">2008-08-28</dateValid><copyrightDate encoding="w3cdtf">2009</copyrightDate></originInfo><language><languageTerm type="code" authority="rfc3066">en</languageTerm><languageTerm type="code" authority="iso639-2b">eng</languageTerm></language><physicalDescription><internetMediaType>text/html</internetMediaType><extent unit="figures">6</extent><extent unit="tables">1</extent><extent unit="references">15</extent><extent unit="words">3335</extent></physicalDescription><abstract lang="en">Multiple system atrophy (MSA) is a neurodegenerative disease characterized clinically by any combination of autonomic, cerebellar, and extrapyramidal symptoms. Autonomic symptoms are usually severe, and urinary symptoms are one of the cardinal features of MSA. Bowel dysfunction and sexual dysfunction are also common in MSA. Quality of life (QOL) in patients with MSA is severely impaired by the presence of pelvic organ dysfunction. Therefore, we aimed to examine the prevalence of pelvic organ dysfunction in patients with MSA. We recruited 256 patients with MSA seen at our neurology clinic. The mean age was 62 years. The control group comprised 158 individuals, and the mean age was 52 years. We administered a questionnaire on pelvic organ dysfunction to the MSA and control groups. The questionnaire had sections focusing on the bladder, bowel, and sexual function. Dysfunction, as described in the responses, was evaluated as normal, mild (>once a month), moderate (>once a week), or severe (>once a day). The Mann‐Whitney's U‐test was used for statistical analysis. When compared with the control group, the prevalence of pelvic organ dysfunction in the MSA group was significantly higher for urinary storage and voiding dysfunction, bowel dysfunction, and sexual dysfunction. QOL in the MSA group was therefore significantly impaired because of urinary dysfunction (70%, 76%), bowel dysfunction (40% of the men), and sexual dysfunction (26%, 45%). Pelvic organ dysfunction is common in MSA, and QOL is severely impaired in patients with MSA. © 2009 Movement Disorder Society</abstract><note type="content">*Potential conflict of interest: None reported.</note><subject lang="en"><genre>Keywords</genre><topic>multiple system atrophy</topic><topic>autonomic dysfunction</topic><topic>pelvic organ dysfunction</topic><topic>urinary dysfunction</topic><topic>quality of life</topic></subject><relatedItem type="host"><titleInfo><title>Movement Disorders</title></titleInfo><titleInfo type="abbreviated"><title>Mov. Disord.</title></titleInfo><subject><genre>article category</genre><topic>Research Article</topic></subject><identifier type="ISSN">0885-3185</identifier><identifier type="eISSN">1531-8257</identifier><identifier type="DOI">10.1002/(ISSN)1531-8257</identifier><identifier type="PublisherID">MDS</identifier><part><date>2009</date><detail type="volume"><caption>vol.</caption><number>24</number></detail><detail type="issue"><caption>no.</caption><number>7</number></detail><extent unit="pages"><start>972</start><end>978</end><total>7</total></extent></part></relatedItem><identifier type="istex">798CC1AD377204E2370ACDAAC8A18B9DD81A22FD</identifier><identifier type="DOI">10.1002/mds.22332</identifier><identifier type="ArticleID">MDS22332</identifier><accessCondition type="use and reproduction" contentType="copyright">Copyright © 2009 Movement Disorder Society</accessCondition><recordInfo><recordOrigin>Wiley Subscription Services, Inc., A Wiley Company</recordOrigin><recordContentSource>WILEY</recordContentSource></recordInfo></mods></metadata><serie></serie></istex></record>Pour manipuler ce document sous Unix (Dilib)
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