Movement Disorders (revue)

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Assessment of autonomic dysfunction in Parkinson's disease: The SCOPA‐AUT

Identifieur interne : 001373 ( Istex/Corpus ); précédent : 001372; suivant : 001374

Assessment of autonomic dysfunction in Parkinson's disease: The SCOPA‐AUT

Auteurs : Martine Visser ; Johan Marinus ; Anne M. Stiggelbout ; Jacobus J. Van Hilten

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RBID : ISTEX:3D5C1896107BC1055954876688E9525F46888556

English descriptors

Abstract

We developed a questionnaire to assess autonomic symptoms in patients with Parkinson's disease (PD) and evaluated its reliability and validity. Based on the results of a postal survey in 46 PD patients, 21 multiple system atrophy patients, and 8 movement disorders specialists, items were included according to their frequency, burden, and clinical relevance. The questionnaire was evaluated in 140 PD patients and 100 controls, and test–retest reliability was established in a sample of 55 PD patients. The SCOPA‐AUT consists of 25 items assessing the following regions: gastrointestinal (7), urinary (6), cardiovascular (3), thermoregulatory (4), pupillomotor (1), and sexual (2 items for men and 2 items for women) dysfunction. Test–retest reliability was good. Autonomic problems increased significantly with increasing disease severity for all autonomic regions, except sexual dysfunction. We conclude that SCOPA‐AUT is a reliable and valid questionnaire that evaluates autonomic dysfunction in PD. © 2004 Movement Disorder Society

Url:
DOI: 10.1002/mds.20153

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ISTEX:3D5C1896107BC1055954876688E9525F46888556

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<namePart type="given">Jacobus J.</namePart>
<namePart type="family">Van Hilten</namePart>
<namePart type="termsOfAddress">MD, PhD</namePart>
<affiliation>Department of Neurology, Leiden University Medical Center, Leiden, The Netherlands</affiliation>
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<dateIssued encoding="w3cdtf">2004-11</dateIssued>
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<abstract lang="en">We developed a questionnaire to assess autonomic symptoms in patients with Parkinson's disease (PD) and evaluated its reliability and validity. Based on the results of a postal survey in 46 PD patients, 21 multiple system atrophy patients, and 8 movement disorders specialists, items were included according to their frequency, burden, and clinical relevance. The questionnaire was evaluated in 140 PD patients and 100 controls, and test–retest reliability was established in a sample of 55 PD patients. The SCOPA‐AUT consists of 25 items assessing the following regions: gastrointestinal (7), urinary (6), cardiovascular (3), thermoregulatory (4), pupillomotor (1), and sexual (2 items for men and 2 items for women) dysfunction. Test–retest reliability was good. Autonomic problems increased significantly with increasing disease severity for all autonomic regions, except sexual dysfunction. We conclude that SCOPA‐AUT is a reliable and valid questionnaire that evaluates autonomic dysfunction in PD. © 2004 Movement Disorder Society</abstract>
<note type="funding">The Netherlands Organisation for Scientific Research - No. 0940‐33‐021; </note>
<subject lang="en">
<genre>Keywords</genre>
<topic>Parkinson's disease</topic>
<topic>autonomic dysfunction</topic>
<topic>questionnaire</topic>
</subject>
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<title>Movement Disorders</title>
<subTitle>Official Journal of the Movement Disorder Society</subTitle>
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<title>Mov. Disord.</title>
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<topic>Brief Report</topic>
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<identifier type="ISSN">0885-3185</identifier>
<identifier type="eISSN">1531-8257</identifier>
<identifier type="DOI">10.1002/(ISSN)1531-8257</identifier>
<identifier type="PublisherID">MDS</identifier>
<part>
<date>2004</date>
<detail type="volume">
<caption>vol.</caption>
<number>19</number>
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<detail type="issue">
<caption>no.</caption>
<number>11</number>
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<start>1306</start>
<end>1312</end>
<total>7</total>
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<accessCondition type="use and reproduction" contentType="copyright">Copyright © 2004 Movement Disorder Society</accessCondition>
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