Transient elevation of cerebrospinal fluid protein in a patient of mild encephalitis with reversible lesion in the splenium: a case report.
Identifieur interne : 001843 ( PubMed/Curation ); précédent : 001842; suivant : 001844Transient elevation of cerebrospinal fluid protein in a patient of mild encephalitis with reversible lesion in the splenium: a case report.
Auteurs : Bhawna Sharma ; Rahul Handa ; Kadam Nagpal ; Swayam Prakash ; Ashok PanagariyaSource :
- The Malaysian journal of medical sciences : MJMS [ 1394-195X ] ; 2014.
Abstract
Mild encephalitis with reversible lesion in the splenium (MERS) is a clinicoradiological syndrome presenting as a solitary lesion in the central portion of the splenium of the corpus callosum (SCC) with a radiological finding of restricted diffusion and low apparent diffusion coefficient (ADC) values. Complete resolution of the lesion on follow-up imaging and full clinical recovery are the hallmarks of this syndrome, even with only supportive therapy. MERS is usually associated with normal Cerebrospinal fluid (CSF) findings and an excellent prognosis, even without corticosteroid therapy. Magnetic resonance imaging (MRI) is the ideal modality for initial diagnosis and follow-up. Not many cases of this uncommon clinicoradiological syndrome with transient elevation of CSF proteins have been reported. In the subsequent sections, we present a case report of this unusual clinicoradiological entity with raised CSF protein. We also elaborate on possible differential diagnoses and the syndrome's proposed pathophysiology.
PubMed: 25246843
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Bhawna Sharma<affiliation><nlm:affiliation>Department of Neurology, Sawai Man Singh Medical College, Jaipur, Rajasthan, PIN: 302004.</nlm:affiliation><wicri:noCountry code="subField">PIN: 302004</wicri:noCountry></affiliation><affiliation><nlm:affiliation>Department of Neurology, Sawai Man Singh Medical College, Jaipur, Rajasthan, PIN: 302004.</nlm:affiliation><wicri:noCountry code="subField">PIN: 302004</wicri:noCountry></affiliation><affiliation><nlm:affiliation>Department of Neurology, Sawai Man Singh Medical College, Jaipur, Rajasthan, PIN: 302004.</nlm:affiliation><wicri:noCountry code="subField">PIN: 302004</wicri:noCountry></affiliation><affiliation><nlm:affiliation>Department of Neurology, Sawai Man Singh Medical College, Jaipur, Rajasthan, PIN: 302004.</nlm:affiliation><wicri:noCountry code="subField">PIN: 302004</wicri:noCountry></affiliation><affiliation><nlm:affiliation>Rajasthan University of Health Sciences (RUHS), Jaipur, Rajasthan, PIN: 302033.</nlm:affiliation><wicri:noCountry code="subField">PIN: 302033</wicri:noCountry></affiliation>Le document en format XML
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302004.</nlm:affiliation><wicri:noCountry code="subField">PIN: 302004</wicri:noCountry></affiliation></author><author><name sortKey="Handa, Rahul" sort="Handa, Rahul" uniqKey="Handa R" first="Rahul" last="Handa">Rahul Handa</name><affiliation><nlm:affiliation>Department of Neurology, Sawai Man Singh Medical College, Jaipur, Rajasthan, PIN: 302004.</nlm:affiliation><wicri:noCountry code="subField">PIN: 302004</wicri:noCountry></affiliation></author><author><name sortKey="Nagpal, Kadam" sort="Nagpal, Kadam" uniqKey="Nagpal K" first="Kadam" last="Nagpal">Kadam Nagpal</name><affiliation><nlm:affiliation>Department of Neurology, Sawai Man Singh Medical College, Jaipur, Rajasthan, PIN: 302004.</nlm:affiliation><wicri:noCountry code="subField">PIN: 302004</wicri:noCountry></affiliation></author><author><name sortKey="Prakash, Swayam" sort="Prakash, Swayam" uniqKey="Prakash S" first="Swayam" last="Prakash">Swayam Prakash</name><affiliation><nlm:affiliation>Department of Neurology, Sawai Man Singh Medical College, Jaipur, Rajasthan, PIN: 302004.</nlm:affiliation><wicri:noCountry code="subField">PIN: 302004</wicri:noCountry></affiliation></author><author><name sortKey="Panagariya, Ashok" sort="Panagariya, Ashok" uniqKey="Panagariya A" first="Ashok" last="Panagariya">Ashok Panagariya</name><affiliation><nlm:affiliation>Rajasthan University of Health Sciences (RUHS), Jaipur, Rajasthan, PIN: 302033.</nlm:affiliation><wicri:noCountry code="subField">PIN: 302033</wicri:noCountry></affiliation></author></analytic><series><title level="j">The Malaysian journal of medical sciences : MJMS</title><idno type="ISSN">1394-195X</idno><imprint><date when="2014" type="published">2014</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Mild encephalitis with reversible lesion in the splenium (MERS) is a clinicoradiological syndrome presenting as a solitary lesion in the central portion of the splenium of the corpus callosum (SCC) with a radiological finding of restricted diffusion and low apparent diffusion coefficient (ADC) values. Complete resolution of the lesion on follow-up imaging and full clinical recovery are the hallmarks of this syndrome, even with only supportive therapy. MERS is usually associated with normal Cerebrospinal fluid (CSF) findings and an excellent prognosis, even without corticosteroid therapy. Magnetic resonance imaging (MRI) is the ideal modality for initial diagnosis and follow-up. Not many cases of this uncommon clinicoradiological syndrome with transient elevation of CSF proteins have been reported. In the subsequent sections, we present a case report of this unusual clinicoradiological entity with raised CSF protein. We also elaborate on possible differential diagnoses and the syndrome's proposed pathophysiology. </div></front></TEI><pubmed><MedlineCitation Status="PubMed-not-MEDLINE" Owner="NLM"><PMID Version="1">25246843</PMID><DateCompleted><Year>2014</Year><Month>09</Month><Day>23</Day></DateCompleted><DateRevised><Year>2018</Year><Month>11</Month><Day>13</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Print">1394-195X</ISSN><JournalIssue CitedMedium="Print"><Volume>21</Volume><Issue>3</Issue><PubDate><Year>2014</Year><Month>May</Month></PubDate></JournalIssue><Title>The Malaysian journal of medical sciences : MJMS</Title><ISOAbbreviation>Malays J Med Sci</ISOAbbreviation></Journal><ArticleTitle>Transient elevation of cerebrospinal fluid protein in a patient of mild encephalitis with reversible lesion in the splenium: a case report.</ArticleTitle><Pagination><MedlinePgn>94-7</MedlinePgn></Pagination><Abstract><AbstractText>Mild encephalitis with reversible lesion in the splenium (MERS) is a clinicoradiological syndrome presenting as a solitary lesion in the central portion of the splenium of the corpus callosum (SCC) with a radiological finding of restricted diffusion and low apparent diffusion coefficient (ADC) values. Complete resolution of the lesion on follow-up imaging and full clinical recovery are the hallmarks of this syndrome, even with only supportive therapy. MERS is usually associated with normal Cerebrospinal fluid (CSF) findings and an excellent prognosis, even without corticosteroid therapy. Magnetic resonance imaging (MRI) is the ideal modality for initial diagnosis and follow-up. Not many cases of this uncommon clinicoradiological syndrome with transient elevation of CSF proteins have been reported. In the subsequent sections, we present a case report of this unusual clinicoradiological entity with raised CSF protein. We also elaborate on possible differential diagnoses and the syndrome's proposed pathophysiology. </AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Sharma</LastName><ForeName>Bhawna</ForeName><Initials>B</Initials><AffiliationInfo><Affiliation>Department of Neurology, Sawai Man Singh Medical College, Jaipur, Rajasthan, PIN: 302004.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Handa</LastName><ForeName>Rahul</ForeName><Initials>R</Initials><AffiliationInfo><Affiliation>Department of Neurology, Sawai Man Singh Medical College, Jaipur, Rajasthan, PIN: 302004.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Nagpal</LastName><ForeName>Kadam</ForeName><Initials>K</Initials><AffiliationInfo><Affiliation>Department of Neurology, Sawai Man Singh Medical College, Jaipur, Rajasthan, PIN: 302004.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Prakash</LastName><ForeName>Swayam</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Department of Neurology, Sawai Man Singh Medical College, Jaipur, Rajasthan, PIN: 302004.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Panagariya</LastName><ForeName>Ashok</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Rajasthan University of Health Sciences (RUHS), Jaipur, Rajasthan, PIN: 302033.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList></Article><MedlineJournalInfo><Country>Malaysia</Country><MedlineTA>Malays J Med Sci</MedlineTA><NlmUniqueID>101126308</NlmUniqueID><ISSNLinking>1394-195X</ISSNLinking></MedlineJournalInfo><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">cerebrospinal fluid protein</Keyword><Keyword MajorTopicYN="N">corpus callosum</Keyword><Keyword MajorTopicYN="N">diffusion magnetic resonance imaging</Keyword><Keyword MajorTopicYN="N">encephalitis</Keyword><Keyword MajorTopicYN="N">reversible lesion</Keyword><Keyword MajorTopicYN="N">splenium</Keyword></KeywordList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2013</Year><Month>10</Month><Day>24</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2014</Year><Month>01</Month><Day>09</Day></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2014</Year><Month>9</Month><Day>24</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2014</Year><Month>9</Month><Day>24</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2014</Year><Month>9</Month><Day>24</Day><Hour>6</Hour><Minute>1</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">25246843</ArticleId><ArticleId IdType="pmc">PMC4163566</ArticleId></ArticleIdList><ReferenceList><Reference><Citation>Ann Indian Acad Neurol. 2012 Apr;15(2):151-7</Citation><ArticleIdList><ArticleId IdType="pubmed">22566735</ArticleId></ArticleIdList></Reference><Reference><Citation>AJNR Am J Neuroradiol. 2006 Apr;27(4):836-8</Citation><ArticleIdList><ArticleId IdType="pubmed">16611774</ArticleId></ArticleIdList></Reference><Reference><Citation>BMJ Case Rep. 2013 Oct 17;2013:null</Citation><ArticleIdList><ArticleId IdType="pubmed">24136911</ArticleId></ArticleIdList></Reference><Reference><Citation>Singapore Med J. 2005 Dec;46(12):726-30</Citation><ArticleIdList><ArticleId IdType="pubmed">16308649</ArticleId></ArticleIdList></Reference><Reference><Citation>Br J Radiol. 2011 Jan;84(997):5-18</Citation><ArticleIdList><ArticleId IdType="pubmed">21172964</ArticleId></ArticleIdList></Reference><Reference><Citation>J Clin Neurol. 2007 Mar;3(1):53-6</Citation><ArticleIdList><ArticleId IdType="pubmed">19513344</ArticleId></ArticleIdList></Reference></ReferenceList></PubmedData></pubmed></record>Pour manipuler ce document sous Unix (Dilib)
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