Middle East respiratory syndrome coronavirus: a comprehensive review.
Identifieur interne : 001290 ( PubMed/Curation ); précédent : 001289; suivant : 001291Middle East respiratory syndrome coronavirus: a comprehensive review.
Auteurs : Mahmoud M. Shehata [Égypte] ; Mokhtar R. Gomaa [Égypte] ; Mohamed A. Ali [Égypte] ; Ghazi Kayali [États-Unis]Source :
- Frontiers of medicine [ 2095-0225 ] ; 2016.
Descripteurs français
- KwdFr :
- Animaux, Antiviraux (usage thérapeutique), Chameaux, Chiroptera, Coronavirus du syndrome respiratoire du Moyen-Orient (), Coronavirus du syndrome respiratoire du Moyen-Orient (physiologie), Flambées de maladies, Furets, Humains, Infection croisée (virologie), Infections à coronavirus (traitement médicamenteux), Infections à coronavirus (transmission), Infections à coronavirus (épidémiologie), Lapins, Macaca mulatta, Mesocricetus, Modèles animaux de maladie humaine, Saisons, Souris, Vaccination (), Vaccins (usage thérapeutique), Voyage.
- MESH :
- physiologie : Coronavirus du syndrome respiratoire du Moyen-Orient.
- traitement médicamenteux : Infections à coronavirus.
- usage thérapeutique : Antiviraux, Infections à coronavirus, Vaccins.
- virologie : Infection croisée.
- épidémiologie : Infections à coronavirus.
- Animaux, Chameaux, Chiroptera, Coronavirus du syndrome respiratoire du Moyen-Orient, Flambées de maladies, Furets, Humains, Lapins, Macaca mulatta, Mesocricetus, Modèles animaux de maladie humaine, Saisons, Souris, Vaccination, Voyage.
English descriptors
- KwdEn :
- Animals, Antiviral Agents (therapeutic use), Camelus, Chiroptera, Coronavirus Infections (drug therapy), Coronavirus Infections (epidemiology), Coronavirus Infections (transmission), Cross Infection (virology), Disease Models, Animal, Disease Outbreaks, Ferrets, Humans, Macaca mulatta, Mesocricetus, Mice, Middle East Respiratory Syndrome Coronavirus (classification), Middle East Respiratory Syndrome Coronavirus (physiology), Rabbits, Seasons, Travel, Vaccination (methods), Vaccines (therapeutic use).
- MESH :
- chemical , therapeutic use : Antiviral Agents, Vaccines.
- classification : Middle East Respiratory Syndrome Coronavirus.
- drug therapy : Coronavirus Infections.
- epidemiology : Coronavirus Infections.
- methods : Vaccination.
- physiology : Middle East Respiratory Syndrome Coronavirus.
- transmission : Coronavirus Infections.
- virology : Cross Infection.
- Animals, Camelus, Chiroptera, Disease Models, Animal, Disease Outbreaks, Ferrets, Humans, Macaca mulatta, Mesocricetus, Mice, Rabbits, Seasons, Travel.
Abstract
The Middle East respiratory syndrome coronavirus was first identified in 2012 and has since then remained uncontrolled. Cases have been mostly reported in the Middle East, however travel-associated cases and outbreaks have also occurred. Nosocomial and zoonotic transmission of the virus appear to be the most important routes. The infection is severe and highly fatal thus necessitating rapid and efficacious interventions. Here, we performed a comprehensive review of published literature and summarized the epidemiology of the virus. In addition, we summarized the virological aspects of the infection and reviewed the animal models used as well as vaccination and antiviral tested against it.
DOI: 10.1007/s11684-016-0430-6
PubMed: 26791756
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Cases have been mostly reported in the Middle East, however travel-associated cases and outbreaks have also occurred. Nosocomial and zoonotic transmission of the virus appear to be the most important routes. The infection is severe and highly fatal thus necessitating rapid and efficacious interventions. Here, we performed a comprehensive review of published literature and summarized the epidemiology of the virus. In addition, we summarized the virological aspects of the infection and reviewed the animal models used as well as vaccination and antiviral tested against it. </div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">26791756</PMID><DateCompleted><Year>2017</Year><Month>04</Month><Day>17</Day></DateCompleted><DateRevised><Year>2020</Year><Month>03</Month><Day>24</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">2095-0225</ISSN><JournalIssue CitedMedium="Internet"><Volume>10</Volume><Issue>2</Issue><PubDate><Year>2016</Year><Month>Jun</Month></PubDate></JournalIssue><Title>Frontiers of medicine</Title><ISOAbbreviation>Front Med</ISOAbbreviation></Journal><ArticleTitle>Middle East respiratory syndrome coronavirus: a comprehensive review.</ArticleTitle><Pagination><MedlinePgn>120-36</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1007/s11684-016-0430-6</ELocationID><Abstract><AbstractText>The Middle East respiratory syndrome coronavirus was first identified in 2012 and has since then remained uncontrolled. Cases have been mostly reported in the Middle East, however travel-associated cases and outbreaks have also occurred. Nosocomial and zoonotic transmission of the virus appear to be the most important routes. The infection is severe and highly fatal thus necessitating rapid and efficacious interventions. Here, we performed a comprehensive review of published literature and summarized the epidemiology of the virus. In addition, we summarized the virological aspects of the infection and reviewed the animal models used as well as vaccination and antiviral tested against it. </AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Shehata</LastName><ForeName>Mahmoud M</ForeName><Initials>MM</Initials><AffiliationInfo><Affiliation>Center of Scientific Excellence for Influenza Viruses, National Research Centre, Giza, Egypt.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Gomaa</LastName><ForeName>Mokhtar R</ForeName><Initials>MR</Initials><AffiliationInfo><Affiliation>Center of Scientific Excellence for Influenza Viruses, National Research Centre, Giza, Egypt.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ali</LastName><ForeName>Mohamed A</ForeName><Initials>MA</Initials><AffiliationInfo><Affiliation>Center of Scientific Excellence for Influenza Viruses, National Research Centre, Giza, 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