Coronaviruses: an overview of their replication and pathogenesis.
Identifieur interne : 001688 ( PubMed/Corpus ); précédent : 001687; suivant : 001689Coronaviruses: an overview of their replication and pathogenesis.
Auteurs : Anthony R. Fehr ; Stanley PerlmanSource :
- Methods in molecular biology (Clifton, N.J.) [ 1940-6029 ] ; 2015.
English descriptors
- KwdEn :
- MESH :
- chemical , genetics : Viral Proteins.
- diagnosis : Coronavirus Infections.
- chemical , metabolism : Viral Proteins.
- physiology : Coronavirus.
- therapy : Coronavirus Infections.
- virology : Coronavirus Infections.
- Animals, Gene Expression, Genome, Viral, Humans, Virus Attachment, Virus Release, Virus Replication.
Abstract
Coronaviruses (CoVs), enveloped positive-sense RNA viruses, are characterized by club-like spikes that project from their surface, an unusually large RNA genome, and a unique replication strategy. Coronaviruses cause a variety of diseases in mammals and birds ranging from enteritis in cows and pigs and upper respiratory disease in chickens to potentially lethal human respiratory infections. Here we provide a brief introduction to coronaviruses discussing their replication and pathogenicity, and current prevention and treatment strategies. We also discuss the outbreaks of the highly pathogenic Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) and the recently identified Middle Eastern Respiratory Syndrome Coronavirus (MERS-CoV).
DOI: 10.1007/978-1-4939-2438-7_1
PubMed: 25720466
Links to Exploration step
pubmed:25720466Le document en format XML
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<front><div type="abstract" xml:lang="en">Coronaviruses (CoVs), enveloped positive-sense RNA viruses, are characterized by club-like spikes that project from their surface, an unusually large RNA genome, and a unique replication strategy. Coronaviruses cause a variety of diseases in mammals and birds ranging from enteritis in cows and pigs and upper respiratory disease in chickens to potentially lethal human respiratory infections. Here we provide a brief introduction to coronaviruses discussing their replication and pathogenicity, and current prevention and treatment strategies. We also discuss the outbreaks of the highly pathogenic Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) and the recently identified Middle Eastern Respiratory Syndrome Coronavirus (MERS-CoV). </div>
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